A novel Schiff base complex with π-conjugated system, [Ni（L1）2（py）2] 1 （L1 =（E）-N′-（2,4-dichlorobenzylidene）-2-oxidobenzohydraizide）, was synthesized and characterized by elemental analysis and single-crys...A novel Schiff base complex with π-conjugated system, [Ni（L1）2（py）2] 1 （L1 =（E）-N′-（2,4-dichlorobenzylidene）-2-oxidobenzohydraizide）, was synthesized and characterized by elemental analysis and single-crystal X-ray determination. Complex 1 crystallizes in the monoclinic system, space group P21/n with a = 12.8286（10）, b = 16.3573（13）, c = 19.0206（14） A, β = 108.2920（10）°, V = 3789.6（5）A^3, Z = 4, Mr = 833.17, Dc = 1.460 g/cm^3,/t = 0.843 mm^-1, F（000） = 1704, the final R = 0.0537 and wR = 0.0640 for 3836 observed reflections with I 〉 2σ（I）. In the molecular structure of 1, the Ni^Ⅱ atoms are six-coordinated by two N and two O atoms from two Schiff base ligands （LI） and two N atoms from two pyridine solvent molecules to form a distorted octahedral geometry. The cytotoxic activities of complex 1 have been experimentally studied against a human HeLa cell in vitro.展开更多
The title complex Zn（HL）（NCS）2 （C14H18N4OS2Zn, Mr = 387.81, HL = N-（3-dimethyl-aminopropyl）-salicylaldimine） has been synthesized by the reaction of ZnSO4·7H2O with the Schiff base N-（3-dimethylaminopro...The title complex Zn（HL）（NCS）2 （C14H18N4OS2Zn, Mr = 387.81, HL = N-（3-dimethyl-aminopropyl）-salicylaldimine） has been synthesized by the reaction of ZnSO4·7H2O with the Schiff base N-（3-dimethylaminopropyl）-salicylaldimine derived from the condensation reaction of 3-dimethylamino- 1-propylamine with salicyladehyde. It crystallizes in the monoclinic system, space group P21/n with a = 9.8360（8）, b = 14.930（1）, c = 12.277（1） A, β= 101.455（2）°, V= 1767.0（3） A 3, Z = 4, F（000） = 800, Dc= 1.458 g/cm^3 and ,μ（MoKα） = 1.631 mm^-1. The structure was refined to R = 0.0463 and wR = 0.1065 for 2681 observed reflections （1 〉 2σ（I））. Crystal analyses revealed that the Zn（Ⅱ） atom is coordinated by two nitrogen atoms of two NCS^-, and an oxygen atom as well as a nitrogen atom of amine from the neutral Schiff base ligand of N-（3-dimethyl-aminopropyl）-salicylaldimine to give a distorted tetrahedral geometry.展开更多
Schiff base derived from amino acid and aldehrde or ketone is an important ligand,which coordinate with metal to form complexes that possess excellent capabilities.The studies of the synthesis approach,biological prop...Schiff base derived from amino acid and aldehrde or ketone is an important ligand,which coordinate with metal to form complexes that possess excellent capabilities.The studies of the synthesis approach,biological properties,catalystal activity and resisting O2-capability in recent years have been summarized in this paper.Moreover some prospects in the future have been given.展开更多
Under microwave irradiation conditions,six Schiff bases containing bi-(4-fluorophenyl)-methyl and 1,3,4-thiadiazole were synthesized via condensation reactions for the first time.The structures of these products were ...Under microwave irradiation conditions,six Schiff bases containing bi-(4-fluorophenyl)-methyl and 1,3,4-thiadiazole were synthesized via condensation reactions for the first time.The structures of these products were analyzed and verified by MS,IR and 1HNMR spectrometry.The antibacterial activities of these compounds were tested.The results showed that compounds 3a and 3b possess good antibacterial activity.All these results had offered some important reference to systematic study on 1,3,4-thiadiazole Schiff Bases compounds in the future.展开更多
基金supported by the National Natural Science Foundation of China (No. 30672516)
文摘A novel Schiff base complex with π-conjugated system, [Ni（L1）2（py）2] 1 （L1 =（E）-N′-（2,4-dichlorobenzylidene）-2-oxidobenzohydraizide）, was synthesized and characterized by elemental analysis and single-crystal X-ray determination. Complex 1 crystallizes in the monoclinic system, space group P21/n with a = 12.8286（10）, b = 16.3573（13）, c = 19.0206（14） A, β = 108.2920（10）°, V = 3789.6（5）A^3, Z = 4, Mr = 833.17, Dc = 1.460 g/cm^3,/t = 0.843 mm^-1, F（000） = 1704, the final R = 0.0537 and wR = 0.0640 for 3836 observed reflections with I 〉 2σ（I）. In the molecular structure of 1, the Ni^Ⅱ atoms are six-coordinated by two N and two O atoms from two Schiff base ligands （LI） and two N atoms from two pyridine solvent molecules to form a distorted octahedral geometry. The cytotoxic activities of complex 1 have been experimentally studied against a human HeLa cell in vitro.
文摘The title complex Zn（HL）（NCS）2 （C14H18N4OS2Zn, Mr = 387.81, HL = N-（3-dimethyl-aminopropyl）-salicylaldimine） has been synthesized by the reaction of ZnSO4·7H2O with the Schiff base N-（3-dimethylaminopropyl）-salicylaldimine derived from the condensation reaction of 3-dimethylamino- 1-propylamine with salicyladehyde. It crystallizes in the monoclinic system, space group P21/n with a = 9.8360（8）, b = 14.930（1）, c = 12.277（1） A, β= 101.455（2）°, V= 1767.0（3） A 3, Z = 4, F（000） = 800, Dc= 1.458 g/cm^3 and ,μ（MoKα） = 1.631 mm^-1. The structure was refined to R = 0.0463 and wR = 0.1065 for 2681 observed reflections （1 〉 2σ（I））. Crystal analyses revealed that the Zn（Ⅱ） atom is coordinated by two nitrogen atoms of two NCS^-, and an oxygen atom as well as a nitrogen atom of amine from the neutral Schiff base ligand of N-（3-dimethyl-aminopropyl）-salicylaldimine to give a distorted tetrahedral geometry.
文摘Schiff base derived from amino acid and aldehrde or ketone is an important ligand,which coordinate with metal to form complexes that possess excellent capabilities.The studies of the synthesis approach,biological properties,catalystal activity and resisting O2-capability in recent years have been summarized in this paper.Moreover some prospects in the future have been given.
文摘Under microwave irradiation conditions,six Schiff bases containing bi-(4-fluorophenyl)-methyl and 1,3,4-thiadiazole were synthesized via condensation reactions for the first time.The structures of these products were analyzed and verified by MS,IR and 1HNMR spectrometry.The antibacterial activities of these compounds were tested.The results showed that compounds 3a and 3b possess good antibacterial activity.All these results had offered some important reference to systematic study on 1,3,4-thiadiazole Schiff Bases compounds in the future.
