Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants...Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants that contain RING-like zinc finger domain and are associated with the regulation of several physiological and biochemical processes.They also play vital roles in plant growth and development such as root formation,leaf development,floral development,hormone biosynthesis,signal transduction,and biotic and abiotic stress responses.Nevertheless,the SRS gene family was not reported in sesame yet.In this study,identification,molecular characterization,phylogenetic relationship,cis-acting regulatory elements,protein-protein interaction,syntenic relationship,duplication events and expression pattern of SRS genes were analyzed in S.indicum.We identified total six SiSRS genes on seven different linkage groups in the S.indicum genome by comparing with the other species,including the model plant Arabidopsis thaliana.The SiSRS genes showed variation in their structure like2–5 exons and 1–4 introns.Like other species,SiSRS proteins also contained‘RING-like zinc finger'and‘LRP1'domains.Then,the SiSRS genes were clustered into subclasses via phylogenetic analysis with proteins of S.indicum,A.thaliana,and some other plant species.The cis-acting regulatory elements analysis revealed that the promoter region of SiSRS4(SIN_1011561)showed the highest 13 and 16 elements for light-and phytohormone-responses whereas,SiSRS1(SIN_1015187)showed the highest 15 elements for stress-response.The ABREs,or ABA-responsive elements,were found in a maximum of 8 copies in the SiSRS3(SIN 1009100).Moreover,the available RNA-seq based expression of SiSRS genes revealed variation in expression patterns between stress-treated and non-treated samples,especially in drought and salinity conditions in.S.indicum.Two SiSRS genes like SiSRS1(SIN_1015187)and SiSRS5(SIN_1021065),also exhibited variable expression patterns between control vs PEG-treated sesame root samples and three SiSRS genes,including SiSRS1(SIN_1015187),SiSRS2(SIN_1003328)and SiSRS5(SIN_1021065)were responsive to salinity treatments.The present outcomes will encourage more research into the gene expression and functionality analysis of SiSRS genes in S.indicum and other related species.展开更多
Sesame(Sesamum indicum L.)is a significantly lucrative cash crop for millions of small-holder farmers.Its seeds are an important source of a highly appreciated vegetable oil globally and two clinically essential antio...Sesame(Sesamum indicum L.)is a significantly lucrative cash crop for millions of small-holder farmers.Its seeds are an important source of a highly appreciated vegetable oil globally and two clinically essential antioxidant lignans,sesamin and sesamolin.Accordingly,many countries import millions of tons of sesame seed every year.The demand for lignan-rich sesame seeds has been increasing in recent years due to the continuous discovery of several pharmacological attributes of sesamin and sesamolin.To meet this demand,the sesame breeder’s primary objective is to release sesame cultivars that are enriched in oil and lignans.Thus,it is necessary to summarize the information related to the sesamin and sesamolin contents in sesame in order to promote the joint efforts of specialized research teams on this important oilseed crop.In this article,we present the current knowledge on the sesamin and sesamolin contents in S.indicum L.with respect to the updated biosynthesis pathway,associated markers,governing loci,available variability in sesame germplasm,the in planta potential roles of these compounds in sesame,and the newly discovered pharmacological attributes.In addition,we propose and discuss some required studies that might facilitate genomics-assisted breeding of high lignan content sesame varieties.展开更多
Objective:To evaluate the potential immunomodulatory effects of an aqueous extract of Sesamum indicum seeds with regard to splenocyte proliferation,Th1/Th2 balance,macrophage function,and the cytotoxic activity of nat...Objective:To evaluate the potential immunomodulatory effects of an aqueous extract of Sesamum indicum seeds with regard to splenocyte proliferation,Th1/Th2 balance,macrophage function,and the cytotoxic activity of natural killer(NK)cells.Methods:Splenocyte proliferation was measured by[~3H]-thymidine incorporation.Griess assay was performed to evaluate the production of nitric oxide by macrophages.The levels of cytokines secreted by splenocytes and macrophages were measured by ELISA.JAM assay was performed to examine the cytotoxic activity of NK cells against YAC-1 tumor cells.Results:Sesamum indicum significantly enhanced splenocyte proliferation in a dose-dependent manner.Sesamum indicum also increased and suppressed the secretion of Th1 and Th2 cytokines,respectively,by splenocytes.The secretion of key pro-inflammatory mediators(IL-6,TNFα,and nitric oxide)by primary macrophages was significantly inhibited by Sesamum indicum.Moreover,Sesamum indicum increased the cytotoxic activity of NK cells against YAC-1 tumor cells.Conclusions:Sesamum indicum shows potent immunomodulatory,anti-inflammatory,and anti-cancer effects.Constituents of Sesamum indicum may be used as effective therapeutic agents in regulating immune reactions implicated in various infectious and noninfectious conditions including cancer.展开更多
Knowledge of genetic diversity is essential for any future varietal improvement program. Thus, the objective of this study is to contribute to a better knowledge of the genetic diversity within 15 sesame accessions, u...Knowledge of genetic diversity is essential for any future varietal improvement program. Thus, the objective of this study is to contribute to a better knowledge of the genetic diversity within 15 sesame accessions, using biochemical markers and RAPD. The accessions are of various sources and seeds of different colors;color being an important feature in the sesame market. SDS-PAGE on protein extracts of sesame seeds revealed 31 protein markers, only 4 of which were polymorphic, indicating that this technique is not suitable for studying genetic diversity in S. indicum. The analyses on isoenzymatic extracts of esterase from sesame seedlings made it possible, to distinguish and classify the accessions into 2 major groups. RAPD analysis of genomic DNA using 10-mer primers revealed a high inter-accession genetic diversity. A total of 53 DNA markers, including 48 polymorphic, were produced. The coefficient of similarity between accessions ranged from 0.343 to 0.897. RAPD markers were found to be more suitable for studying genetic diversity within sesame germplasm than isozyme analyzes. Nevertheless, geographical distributions and seed colors are not related to the classes formed.展开更多
Sesame (Sesamum indicum Linn.) (Pedaliaceae) is an important oilseed crop grown in many countries. Among the insect pests infesting sesame, the webworm, Antigastra catalaunalis Duponchel (Pyraustidae: Lepidoptera) is ...Sesame (Sesamum indicum Linn.) (Pedaliaceae) is an important oilseed crop grown in many countries. Among the insect pests infesting sesame, the webworm, Antigastra catalaunalis Duponchel (Pyraustidae: Lepidoptera) is predominant throughout the crop period. For managing this insect, resistant sesame varieties with higher yield potential and better adaptability to varied locations are essentially needed. Keeping this in view and based on earlier work, three promising accessions viz., IVTS-2001-7, KMR-102 and TMV-3 were selected. To enhance resistance and/or yield traits, these three accessions in comparison with a susceptible check SVPR 1 were subjected to mutagenesis using gamma rays as physical mutagen;Ethyl Methane Sulphonate (EMS) and Diethyl Sulphate (DES) as chemical mutants. The first and generation mutants were evaluated under field conditions at Methikudi village, Cuddalore district, Tamil Nadu, Southern India during May, 2012-September, 2014. Webworm infestation was evaluated based on leaf, flower and capsule damage. Among the first mutant (M1) and second mutant (M2) generations, plants of the accessions namely IVTS 2001-7 and TMV-3 were rated as resistant and plants of SVPR-1 were highly susceptible to A. catalaunalis.展开更多
Sesamum indicum L. (family: Pedaliaceae) is an economically important oil seed crop grown in tropical and sub-tropical countries. It is widely used in food, nutraceutical, pharmaceutical industries. Sesamum is widely ...Sesamum indicum L. (family: Pedaliaceae) is an economically important oil seed crop grown in tropical and sub-tropical countries. It is widely used in food, nutraceutical, pharmaceutical industries. Sesamum is widely distributed in all the climatic stages and great diversity. The exploration of genetic diversity is a pre-requisite for genome organization in the landraces and the related domesticated ones. Agromorphological and molecular markers were used to assess the identification of 33 Sesamum genotypes and determination of the genetic relationships among these genotypes. Out of 30 Inter-Simple Sequence Repeat (ISSR) primers tested, 18 primers produced 114 detectable fragments, of which 97 (85.08%) were polymorphic across the varieties. Molecular profiling could be solely used for their identification of genotypes. Genetic relationships among these genotypes were evaluated by generating a similarity matrix based on the Jacard’s coefficient and the Unweighted Pair Group Method with Arithmetic Average (UPGMA) dendogram. The results showed a clear cut separation of the 33 genotypes and were in broad agreement with the morphology. Both molecular and morphological markers will be useful for preservation of the germplasm as well as breeding program.展开更多
Sesame cultivation is strategic for the economy of Burkina Faso. Indeed, after cotton, sesame is the second most important agricultural product for exportation. However, its production is limited by plant diseases and...Sesame cultivation is strategic for the economy of Burkina Faso. Indeed, after cotton, sesame is the second most important agricultural product for exportation. However, its production is limited by plant diseases and pest attacks. Facing this situation, large amounts of pesticides are used to boost productivity. But, these chemicals have a negative impact on soil fertility. In this instance, the effects of Supraxone and Lambda-super in the presence of compost on soil microbial activity under rainfed sesame cultivation in a peasant environment were studied. The experiment design was a block of Fisher (BCR) comparing the non-treated parcel (TNT) to the parcel amended only with compost (C) and to the parcel amended with compost and treated with the pesticides (C + P), respectively. Soil samples were taken at depths of 0 - 20 cm before sowing at 41st and 81st days after sowing. Respiratory activity and soil microbial biomass were monitored respectively by respirometric tests and by the fumigation-incubation method. The results show that the addition of compost into the soil with or without supraxone treatment and Lambda-super resulted in an increase in microbial biomass and soil respiratory quotient. These results show that the provision of compost in sufficient quantity corrects the inhibitory effect of soil biological activity by pesticides.展开更多
Genetic diversity of Moroccan sesame(Sesamum indicum L.)was analyzed for the first time using agro-morphological traits.Thirty-three sesame populations collected from Tadla region in Morocco were evaluated for 13 para...Genetic diversity of Moroccan sesame(Sesamum indicum L.)was analyzed for the first time using agro-morphological traits.Thirty-three sesame populations collected from Tadla region in Morocco were evaluated for 13 parameters in three contrasted environments,Afr-13,Afr-14 and Atj-14.Broad and significant variation among populations was observed only for three agro-morphologic traits,namely first capsule height(FCH),number of seeds per capsule(NSC)and thousand seeds weight(TSW).The respective overall averages were 71.82 cm(ranging from 65 cm to 77 cm),61.39(varying from 57 to 65)and 3.20 g(ranging from 3.0 g to 3.4 g).Environment had a highly significant effect on all studied parameters,except capsule size and oil content.The obtained mean values of parameters studied showed that environment Afr-14 was the most favorable for most of them,particularly seed yield(1.32 t/ha)and TSW(3.57 g).Significant and interesting correlations were observed between seed yield per plant(SYP)and other parameters.As relevant implication of this finding,number of capsules per plant(NCP)and NSC could be used as valuable selection criteria in sesame breeding program.However,limited and non-significant variation among sesame populations for most of parameters studied suggests that they are genetically very close and may be derived from a single cultivar or germplasm.Molecular characterization is needed to confirm or refute this hypothesis.Besides,when compared with sesame grown throughout the world,Moroccan sesame was found to be very promising,which open up the possibility to develop this crop in this country.展开更多
Studies on Soil Test Crop Response Based Integrated Plant Nutrition System(STCR-IPNS)were conducted for three years adopting the Inductive cum Targeted Yield Model,on alfisols of Unified Andhra Pradesh,Southern India ...Studies on Soil Test Crop Response Based Integrated Plant Nutrition System(STCR-IPNS)were conducted for three years adopting the Inductive cum Targeted Yield Model,on alfisols of Unified Andhra Pradesh,Southern India during summer 2016-2018 in order to develop fertilizer prescriptions through IPNS for the desired yield targets of Sesamum under field conditions.The bases for making the fertilizer prescriptions viz.nutrient requirement(NR),contribution of nutrients from soil(Cs),fertilizer(Cf)and vermicompost(CVC)were computed using the field experimental data.Making use of these basic parameters,the fertilizer prescription equations were developed under NPK alone and under IPNS for the desired yield targets of Sesamum for a range of soil test values.The quantity of fertilizers contributed by the application of vermicompost was assessed.Nutrient requirement to produce 100 kg of sesame seed was worked out to be 10.20 kg N,3.90 kg P2O5 and 5.22 kg K2O.In the present investigation,the requirement of N was higher which is followed by K2O and P2O5.The requirement of N was 2.62 times higher than P and 1.95 times higher than K.The percent contribution of N,P and K was 12.25,15.75 and 6.00 from soils,41.68,22.85 and 59.97 from fertilizer and 9.87,6.74 and 18.65 from organic manures,respectively.Thus the Inductive cum Targeted Yield Model used to develop fertilizer prescription equations provides a strong basis for soil fertility maintenance consistent with high productivity and efficient nutrient management in farming for sustainable and enduring agriculture.展开更多
文摘Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants that contain RING-like zinc finger domain and are associated with the regulation of several physiological and biochemical processes.They also play vital roles in plant growth and development such as root formation,leaf development,floral development,hormone biosynthesis,signal transduction,and biotic and abiotic stress responses.Nevertheless,the SRS gene family was not reported in sesame yet.In this study,identification,molecular characterization,phylogenetic relationship,cis-acting regulatory elements,protein-protein interaction,syntenic relationship,duplication events and expression pattern of SRS genes were analyzed in S.indicum.We identified total six SiSRS genes on seven different linkage groups in the S.indicum genome by comparing with the other species,including the model plant Arabidopsis thaliana.The SiSRS genes showed variation in their structure like2–5 exons and 1–4 introns.Like other species,SiSRS proteins also contained‘RING-like zinc finger'and‘LRP1'domains.Then,the SiSRS genes were clustered into subclasses via phylogenetic analysis with proteins of S.indicum,A.thaliana,and some other plant species.The cis-acting regulatory elements analysis revealed that the promoter region of SiSRS4(SIN_1011561)showed the highest 13 and 16 elements for light-and phytohormone-responses whereas,SiSRS1(SIN_1015187)showed the highest 15 elements for stress-response.The ABREs,or ABA-responsive elements,were found in a maximum of 8 copies in the SiSRS3(SIN 1009100).Moreover,the available RNA-seq based expression of SiSRS genes revealed variation in expression patterns between stress-treated and non-treated samples,especially in drought and salinity conditions in.S.indicum.Two SiSRS genes like SiSRS1(SIN_1015187)and SiSRS5(SIN_1021065),also exhibited variable expression patterns between control vs PEG-treated sesame root samples and three SiSRS genes,including SiSRS1(SIN_1015187),SiSRS2(SIN_1003328)and SiSRS5(SIN_1021065)were responsive to salinity treatments.The present outcomes will encourage more research into the gene expression and functionality analysis of SiSRS genes in S.indicum and other related species.
基金study was supported by the Open Project of Key Laboratory of Biology and Genetic Improvement of Oil Crops,Ministry of Agriculture and Rural Affairs,China(KF2020004,KF2022002)the Agricultural Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences(CAAS-ASTIP-2016-OCRI)+3 种基金the Key Research Projects of Hubei Province,China(2020BBA045,2020BHB028)the Science and Technology Innovation Project of Hubei Province,China(2021-620-000-001-035)the China Agriculture Research System of MOF and MARA(CARS-14)the Fundamental Research Funds for Central Non-profit Scientific Institution,China(Y2022XK11).
文摘Sesame(Sesamum indicum L.)is a significantly lucrative cash crop for millions of small-holder farmers.Its seeds are an important source of a highly appreciated vegetable oil globally and two clinically essential antioxidant lignans,sesamin and sesamolin.Accordingly,many countries import millions of tons of sesame seed every year.The demand for lignan-rich sesame seeds has been increasing in recent years due to the continuous discovery of several pharmacological attributes of sesamin and sesamolin.To meet this demand,the sesame breeder’s primary objective is to release sesame cultivars that are enriched in oil and lignans.Thus,it is necessary to summarize the information related to the sesamin and sesamolin contents in sesame in order to promote the joint efforts of specialized research teams on this important oilseed crop.In this article,we present the current knowledge on the sesamin and sesamolin contents in S.indicum L.with respect to the updated biosynthesis pathway,associated markers,governing loci,available variability in sesame germplasm,the in planta potential roles of these compounds in sesame,and the newly discovered pharmacological attributes.In addition,we propose and discuss some required studies that might facilitate genomics-assisted breeding of high lignan content sesame varieties.
文摘Objective:To evaluate the potential immunomodulatory effects of an aqueous extract of Sesamum indicum seeds with regard to splenocyte proliferation,Th1/Th2 balance,macrophage function,and the cytotoxic activity of natural killer(NK)cells.Methods:Splenocyte proliferation was measured by[~3H]-thymidine incorporation.Griess assay was performed to evaluate the production of nitric oxide by macrophages.The levels of cytokines secreted by splenocytes and macrophages were measured by ELISA.JAM assay was performed to examine the cytotoxic activity of NK cells against YAC-1 tumor cells.Results:Sesamum indicum significantly enhanced splenocyte proliferation in a dose-dependent manner.Sesamum indicum also increased and suppressed the secretion of Th1 and Th2 cytokines,respectively,by splenocytes.The secretion of key pro-inflammatory mediators(IL-6,TNFα,and nitric oxide)by primary macrophages was significantly inhibited by Sesamum indicum.Moreover,Sesamum indicum increased the cytotoxic activity of NK cells against YAC-1 tumor cells.Conclusions:Sesamum indicum shows potent immunomodulatory,anti-inflammatory,and anti-cancer effects.Constituents of Sesamum indicum may be used as effective therapeutic agents in regulating immune reactions implicated in various infectious and noninfectious conditions including cancer.
文摘Knowledge of genetic diversity is essential for any future varietal improvement program. Thus, the objective of this study is to contribute to a better knowledge of the genetic diversity within 15 sesame accessions, using biochemical markers and RAPD. The accessions are of various sources and seeds of different colors;color being an important feature in the sesame market. SDS-PAGE on protein extracts of sesame seeds revealed 31 protein markers, only 4 of which were polymorphic, indicating that this technique is not suitable for studying genetic diversity in S. indicum. The analyses on isoenzymatic extracts of esterase from sesame seedlings made it possible, to distinguish and classify the accessions into 2 major groups. RAPD analysis of genomic DNA using 10-mer primers revealed a high inter-accession genetic diversity. A total of 53 DNA markers, including 48 polymorphic, were produced. The coefficient of similarity between accessions ranged from 0.343 to 0.897. RAPD markers were found to be more suitable for studying genetic diversity within sesame germplasm than isozyme analyzes. Nevertheless, geographical distributions and seed colors are not related to the classes formed.
文摘Sesame (Sesamum indicum Linn.) (Pedaliaceae) is an important oilseed crop grown in many countries. Among the insect pests infesting sesame, the webworm, Antigastra catalaunalis Duponchel (Pyraustidae: Lepidoptera) is predominant throughout the crop period. For managing this insect, resistant sesame varieties with higher yield potential and better adaptability to varied locations are essentially needed. Keeping this in view and based on earlier work, three promising accessions viz., IVTS-2001-7, KMR-102 and TMV-3 were selected. To enhance resistance and/or yield traits, these three accessions in comparison with a susceptible check SVPR 1 were subjected to mutagenesis using gamma rays as physical mutagen;Ethyl Methane Sulphonate (EMS) and Diethyl Sulphate (DES) as chemical mutants. The first and generation mutants were evaluated under field conditions at Methikudi village, Cuddalore district, Tamil Nadu, Southern India during May, 2012-September, 2014. Webworm infestation was evaluated based on leaf, flower and capsule damage. Among the first mutant (M1) and second mutant (M2) generations, plants of the accessions namely IVTS 2001-7 and TMV-3 were rated as resistant and plants of SVPR-1 were highly susceptible to A. catalaunalis.
文摘Sesamum indicum L. (family: Pedaliaceae) is an economically important oil seed crop grown in tropical and sub-tropical countries. It is widely used in food, nutraceutical, pharmaceutical industries. Sesamum is widely distributed in all the climatic stages and great diversity. The exploration of genetic diversity is a pre-requisite for genome organization in the landraces and the related domesticated ones. Agromorphological and molecular markers were used to assess the identification of 33 Sesamum genotypes and determination of the genetic relationships among these genotypes. Out of 30 Inter-Simple Sequence Repeat (ISSR) primers tested, 18 primers produced 114 detectable fragments, of which 97 (85.08%) were polymorphic across the varieties. Molecular profiling could be solely used for their identification of genotypes. Genetic relationships among these genotypes were evaluated by generating a similarity matrix based on the Jacard’s coefficient and the Unweighted Pair Group Method with Arithmetic Average (UPGMA) dendogram. The results showed a clear cut separation of the 33 genotypes and were in broad agreement with the morphology. Both molecular and morphological markers will be useful for preservation of the germplasm as well as breeding program.
文摘Sesame cultivation is strategic for the economy of Burkina Faso. Indeed, after cotton, sesame is the second most important agricultural product for exportation. However, its production is limited by plant diseases and pest attacks. Facing this situation, large amounts of pesticides are used to boost productivity. But, these chemicals have a negative impact on soil fertility. In this instance, the effects of Supraxone and Lambda-super in the presence of compost on soil microbial activity under rainfed sesame cultivation in a peasant environment were studied. The experiment design was a block of Fisher (BCR) comparing the non-treated parcel (TNT) to the parcel amended only with compost (C) and to the parcel amended with compost and treated with the pesticides (C + P), respectively. Soil samples were taken at depths of 0 - 20 cm before sowing at 41st and 81st days after sowing. Respiratory activity and soil microbial biomass were monitored respectively by respirometric tests and by the fumigation-incubation method. The results show that the addition of compost into the soil with or without supraxone treatment and Lambda-super resulted in an increase in microbial biomass and soil respiratory quotient. These results show that the provision of compost in sufficient quantity corrects the inhibitory effect of soil biological activity by pesticides.
文摘Genetic diversity of Moroccan sesame(Sesamum indicum L.)was analyzed for the first time using agro-morphological traits.Thirty-three sesame populations collected from Tadla region in Morocco were evaluated for 13 parameters in three contrasted environments,Afr-13,Afr-14 and Atj-14.Broad and significant variation among populations was observed only for three agro-morphologic traits,namely first capsule height(FCH),number of seeds per capsule(NSC)and thousand seeds weight(TSW).The respective overall averages were 71.82 cm(ranging from 65 cm to 77 cm),61.39(varying from 57 to 65)and 3.20 g(ranging from 3.0 g to 3.4 g).Environment had a highly significant effect on all studied parameters,except capsule size and oil content.The obtained mean values of parameters studied showed that environment Afr-14 was the most favorable for most of them,particularly seed yield(1.32 t/ha)and TSW(3.57 g).Significant and interesting correlations were observed between seed yield per plant(SYP)and other parameters.As relevant implication of this finding,number of capsules per plant(NCP)and NSC could be used as valuable selection criteria in sesame breeding program.However,limited and non-significant variation among sesame populations for most of parameters studied suggests that they are genetically very close and may be derived from a single cultivar or germplasm.Molecular characterization is needed to confirm or refute this hypothesis.Besides,when compared with sesame grown throughout the world,Moroccan sesame was found to be very promising,which open up the possibility to develop this crop in this country.
基金This work was carried out under part of AICRP on Soil Test Crop Response,ICAR at PJTSAU,Hyderabad-500030,India.
文摘Studies on Soil Test Crop Response Based Integrated Plant Nutrition System(STCR-IPNS)were conducted for three years adopting the Inductive cum Targeted Yield Model,on alfisols of Unified Andhra Pradesh,Southern India during summer 2016-2018 in order to develop fertilizer prescriptions through IPNS for the desired yield targets of Sesamum under field conditions.The bases for making the fertilizer prescriptions viz.nutrient requirement(NR),contribution of nutrients from soil(Cs),fertilizer(Cf)and vermicompost(CVC)were computed using the field experimental data.Making use of these basic parameters,the fertilizer prescription equations were developed under NPK alone and under IPNS for the desired yield targets of Sesamum for a range of soil test values.The quantity of fertilizers contributed by the application of vermicompost was assessed.Nutrient requirement to produce 100 kg of sesame seed was worked out to be 10.20 kg N,3.90 kg P2O5 and 5.22 kg K2O.In the present investigation,the requirement of N was higher which is followed by K2O and P2O5.The requirement of N was 2.62 times higher than P and 1.95 times higher than K.The percent contribution of N,P and K was 12.25,15.75 and 6.00 from soils,41.68,22.85 and 59.97 from fertilizer and 9.87,6.74 and 18.65 from organic manures,respectively.Thus the Inductive cum Targeted Yield Model used to develop fertilizer prescription equations provides a strong basis for soil fertility maintenance consistent with high productivity and efficient nutrient management in farming for sustainable and enduring agriculture.