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Topology Optimization of Metamaterial Microstructures for Negative Poisson’s Ratio under Large Deformation Using a Gradient-Free Method
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作者 Weida Wu Yiqiang Wang +1 位作者 Zhonghao Gao Pai Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期2001-2026,共26页
Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching... Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching,NPR metamaterials designed under small strain assumption may experience a rapid degradation in NPR performance.To address this issue,this study aims to design metamaterials maintaining a targeted NPR under large deformation by taking advantage of the geometry nonlinearity mechanism.A representative periodic unit cell is modeled considering geometry nonlinearity,and its topology is designed using a gradient-free method.The unit cell microstructural topologies are described with the material-field series-expansion(MFSE)method.The MFSE method assumes spatial correlation of the material distribution,which greatly reduces the number of required design variables.To conveniently design metamaterials with desired NPR under large deformation,we propose a two-stage gradient-free metamaterial topology optimization method,which fully takes advantage of the dimension reduction benefits of the MFSE method and the Kriging surrogate model technique.Initially,we use homogenization to find a preliminary NPR design under a small deformation assumption.In the second stage,we begin with this preliminary design and minimize deviations in NPR from a targeted value under large deformation.Using this strategy and solution technique,we successfully obtain a group of NPR metamaterials that can sustain different desired NPRs in the range of[−0.8,−0.1]under uniaxial stretching up to 20% strain.Furthermore,typical microstructure designs are fabricated and tested through experiments.The experimental results show good consistency with our numerical results,demonstrating the effectiveness of the present gradientfree NPR metamaterial design strategy. 展开更多
关键词 Topology optimization microstructural design negative Poisson’s ratio large deformation
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A gated recurrent unit model to predict Poisson’s ratio using deep learning
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作者 Fahd Saeed Alakbari Mysara Eissa Mohyaldinn +4 位作者 Mohammed Abdalla Ayoub Ibnelwaleed A.Hussein Ali Samer Muhsan Syahrir Ridha Abdullah Abduljabbar Salih 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期123-135,共13页
Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to spe... Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs. 展开更多
关键词 static Poisson’s ratio Deep learning Gated recurrent unit(GRU) sand control Trend analysis Geomechanical properties
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How to compare market efficiency? The Sharpe ratio based on the ARMA-GARCH forecast 被引量:5
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作者 Lin Liu Qiguang Chen 《Financial Innovation》 2020年第1期682-702,共21页
This paper derives a new method for comparing the weak-form efficiency of markets.The author derives the formula of the Sharpe ratio from the ARMA-GARCH model and finds that the Sharpe ratio just depends on the coeffi... This paper derives a new method for comparing the weak-form efficiency of markets.The author derives the formula of the Sharpe ratio from the ARMA-GARCH model and finds that the Sharpe ratio just depends on the coefficients of the AR and MA terms and is not affected by the GARCH process.For empirical purposes,the Sharpe ratio can be formulated with a monotonic increasing function of R-squared if the sample size is large enough.One can utilize the Sharpe ratio to compare weak-form efficiency among different markets.The results of stochastic simulation demonstrate the validity of the proposed method.The author also constructs empirical AR-GARCH models and computes the Sharpe ratio for S&P 500 Index and the SSE Composite Index. 展开更多
关键词 ARMA GARCH Measurement of market efficiency sharpe ratio stochastic simulation
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用于择优决策的广义Sharpe比率 被引量:1
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作者 倪苏云 吴冲锋 《系统工程》 CSCD 北大核心 2001年第5期33-36,共4页
在 Dowd对备选资产是否值得投资的研究基础上 ,推导出在可供选择的不同备选资产中择优投资的判据 ,从而扩展了广义 Sharpe比率的使用范围 ,解决了备选资产与原有投资组合中其他资产的收益存在相关性时 ,标准 Sharpe比率无法应用的问题... 在 Dowd对备选资产是否值得投资的研究基础上 ,推导出在可供选择的不同备选资产中择优投资的判据 ,从而扩展了广义 Sharpe比率的使用范围 ,解决了备选资产与原有投资组合中其他资产的收益存在相关性时 ,标准 Sharpe比率无法应用的问题。最后 ,还用图示分析了基准选取不合适可能造成的计算误差。 展开更多
关键词 决策判据 投资组合 广义sharpe比率 证券
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Sharpe比率与RR比率的一致性研究
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作者 文平 贾达明 《常州工学院学报》 2016年第1期1-5,共5页
研究发现在位置-尺度分布族中,只要RR比率中的风险测度与报酬测度满足正齐次性与平移不变性,根据RR比率进行的投资业绩排名与用Sharpe比率的排名是一致的。由于文中的RR比率中的风险测度与报酬测度均满足正齐次性与平移不变性,故在位置... 研究发现在位置-尺度分布族中,只要RR比率中的风险测度与报酬测度满足正齐次性与平移不变性,根据RR比率进行的投资业绩排名与用Sharpe比率的排名是一致的。由于文中的RR比率中的风险测度与报酬测度均满足正齐次性与平移不变性,故在位置-尺度分布族中使用Sharpe比率作为业绩评价指标是一种不错的选择。 展开更多
关键词 sharpe比率 RR比率 位置-尺度分布族 测度
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基于XGBoost算法的v_(P)/v_(S)预测及其在储层检测中的应用
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作者 田仁飞 李山 +1 位作者 刘涛 景洋 《石油地球物理勘探》 EI CSCD 北大核心 2024年第4期653-663,共11页
鄂尔多斯盆地碳酸盐岩地层蕴含着丰富的油气资源。在勘探实践中发现,大牛地气田马家沟组断层发育、断距小,类型多样且成因复杂,给勘探、开发带来了较多挑战。为了应对这些挑战,提高储层预测的精度变得至关重要。在分析大牛地气田敏感弹... 鄂尔多斯盆地碳酸盐岩地层蕴含着丰富的油气资源。在勘探实践中发现,大牛地气田马家沟组断层发育、断距小,类型多样且成因复杂,给勘探、开发带来了较多挑战。为了应对这些挑战,提高储层预测的精度变得至关重要。在分析大牛地气田敏感弹性参数的基础上,建立地震属性与储层纵横波速度比(v_(P)/v_(S))的关系,提出一种基于XGBoost算法的地震多属性v_(P)/v_(S)预测方法。为了进一步提升XGBoost算法的预测精度和泛化能力,采用贝叶斯算法对XGBoost算法的超参数进行优化,从而找到最佳的超参数组合,以确保模型在训练集和测试集上的性能均能得到提升。将XGBoost算法应用于Marmousi 2模型进行横波速度预测,预测值与实际值相关系数超过0.88,而均方误差、平均绝对百分比误差分别低于6.55×10^(-7)和4%,验证了该方法的准确性和可靠性。在鄂尔多斯盆地大牛地气田,应用该方法获得的v_(P)/v_(S)成功识别出含气储层,结果与实际钻井数据一致。理论模型和实际数据应用结果表明,XGBoost作为一种强大的机器学习算法预测精度较高,为直接由叠后地震属性预测v_(P)/v_(S)提供了一种有效的途径。 展开更多
关键词 横波速度 碳酸盐岩储层 地震属性 XGBoost算法 纵横波速度比(v_(P)/v_(s))
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基于SVM-Sharpe方法的动量策略在沪深300市场中的应用 被引量:1
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作者 马雪 陈盛双 余放 《武汉理工大学学报(信息与管理工程版)》 CAS 2016年第5期580-584,共5页
为了提高动量策略的性能,在J/T方法的基础上,提出了新的动量策略并检验我国沪深300市场的有效性,即在C-SVM算法预测股市买点前提下,构造了基于夏普比率方法的动量策略。结果表明,我国股市在短期内存在明显的反转现象,在中长期存在明显... 为了提高动量策略的性能,在J/T方法的基础上,提出了新的动量策略并检验我国沪深300市场的有效性,即在C-SVM算法预测股市买点前提下,构造了基于夏普比率方法的动量策略。结果表明,我国股市在短期内存在明显的反转现象,在中长期存在明显的动量现象,这一现象对我国证券市场的发展和沪深300市场投资者具有参考价值。 展开更多
关键词 动量策略 反转策略 支持向量机 夏普比率
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修正的Sharpe比率在基金评价中的应用 被引量:1
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作者 薛原 胡云姣 《北京化工大学学报(自然科学版)》 CAS CSCD 北大核心 2017年第1期111-117,共7页
为了解决传统Sharpe比率中将投资收益的标准差作为风险度量时存在的问题,同时考虑金融资产收益率分布的偏度和峰度共存、不服从正态分布和具有杠杆效应的特性,应用指数形式广义自回归条件异方差模型(EGARCH模型)在3种分布(正态分布、t... 为了解决传统Sharpe比率中将投资收益的标准差作为风险度量时存在的问题,同时考虑金融资产收益率分布的偏度和峰度共存、不服从正态分布和具有杠杆效应的特性,应用指数形式广义自回归条件异方差模型(EGARCH模型)在3种分布(正态分布、t分布和GED分布)假设下计算风险价值,以代替Sharpe比率中的标准差。另外,构建了流动性因子并将其应用到Sharpe比率的计算中。结果表明:经过修正的Sharpe比率能够很好地评价基金绩效。 展开更多
关键词 基金评价 sharpe比率 非对称EGARCH模型 流动性风险
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Model test of negative Poisson’s ratio cable for supporting super-largespan tunnel using excavation compensation method
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作者 Manchao He Aipeng Guo +4 位作者 Zhifeng Du Songyuan Liu Chun Zhu Shiding Cao Zhigang Tao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第6期1355-1369,共15页
In recent years,there is a scenario in urban tunnel constructions to build super-large-span tunnels for traffic diversion and route optimization purposes.However,the increased size makes tunnel support more difficult.... In recent years,there is a scenario in urban tunnel constructions to build super-large-span tunnels for traffic diversion and route optimization purposes.However,the increased size makes tunnel support more difficult.Unfortunately,there are few studies on the failure and support mechanism of the surrounding rocks in the excavation of supported tunnel,while most model tests of super-large-span tunnels focus on the failure characteristics of surrounding rocks in tunnel excavation without supports.Based on excavation compensation method(ECM),model tests of a super-large-span tunnel excavation by different anchor cable support methods in the initial support stage were carried out.The results indicate that during excavation of super-large-span tunnel,the stress and displacement of the shallow surrounding rocks decrease,following a step-shape pattern,and the tunnel failure is mainly concentrated on the vault and spandrel areas.Compared with conventional anchor cable supports,the NPR(negative Poisson’s ratio)anchor cable support is more suitable for the initial support stage of the super-large-span tunnels.The tunnel support theory,model test materials,methods,and the results obtained in this study could provide references for study of similar super-large-span tunnels。 展开更多
关键词 super-large-span tunnel Excavation compensation method(ECM) NPR(Negative Poisson’s ratio)anchor cable Model test
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Cox-Ingersoll-Ross过程对数似然比的精细大偏差
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作者 吕亚倩 赵守江 《数学杂志》 2024年第1期35-46,共12页
本文研究了平稳状态下Cox-Ingersoll-Ross过程在原假设和备择假设下对数似然比的精细大偏差问题.利用测度变换和特征函数技巧,本文得到了对数似然比的完全展开式.
关键词 Cox-Ingersoll-Ross过程 对数似然比 精细大偏差
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A high resolution inversion method for fluid factor with dynamic dryrock V_(P)/V_(S) ratio squared
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作者 Lin Zhou Jian-Ping Liao +3 位作者 Xing-Ye Liu Pu Wang Ya-Nan Guo Jing-Ye Li 《Petroleum Science》 SCIE EI CSCD 2023年第5期2822-2834,共13页
As an important indicator parameter of fluid identification,fluid factor has always been a concern for scholars.However,when predicting Russell fluid factor or effective pore-fluid bulk modulus,it is necessary to intr... As an important indicator parameter of fluid identification,fluid factor has always been a concern for scholars.However,when predicting Russell fluid factor or effective pore-fluid bulk modulus,it is necessary to introduce a new rock skeleton parameter which is the dry-rock VP/VS ratio squared(DVRS).In the process of fluid factor calculation or inversion,the existing methods take this parameter as a static constant,which has been estimated in advance,and then apply it to the fluid factor calculation and inversion.The fluid identification analysis based on a portion of the Marmousi 2 model and numerical forward modeling test show that,taking the DVRS as a static constant will limit the identification ability of fluid factor and reduce the inversion accuracy.To solve the above problems,we proposed a new method to regard the DVRS as a dynamic variable varying with depth and lithology for the first time,then apply it to fluid factor calculation and inversion.Firstly,the exact Zoeppritz equations are rewritten into a new form containing the fluid factor and DVRS of upper and lower layers.Next,the new equations are applied to the four parameters simultaneous inversion based on the generalized nonlinear inversion(GNI)method.The testing results on a portion of the Marmousi 2 model and field data show that dynamic DVRS can significantly improve the fluid factor identification ability,effectively suppress illusion.Both synthetic and filed data tests also demonstrate that the GNI method based on Bayesian deterministic inversion(BDI)theory can successfully solve the above four parameter simultaneous inversion problem,and taking the dynamic DVRS as a target inversion parameter can effectively improve the inversion accuracy of fluid factor.All these results completely verified the feasibility and effectiveness of the proposed method. 展开更多
关键词 Fluid factor Dry-rock V_(P)/V_(s)ratio squared(DVRs) Dynamic variable Multiple parameters simultaneous inversion Generalized nonlinear inversion(GNI)
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Mg/Ca,Ba/Ca,and S/Ca ratios as environmental and growth proxies for bivalve shells from the Haima cold seep,South China Sea
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作者 Jingya CAO Shengxiong YANG +2 位作者 Danling TANG Junxi FENG Jinqiang LIANG 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2023年第2期660-672,共13页
Bivalve shell fossils,cemented by authigenic carbonates,are widely spread in the Haima cold seep,Qiongdongnan Basin of the South China Sea(SCS).In this study,we examined an element profile of Gigantidas platifrons in ... Bivalve shell fossils,cemented by authigenic carbonates,are widely spread in the Haima cold seep,Qiongdongnan Basin of the South China Sea(SCS).In this study,we examined an element profile of Gigantidas platifrons in the Haima cold seeps at a water depth of 1381 m.Based on the scanning electron microscope(SEM)analyses,the prismatic layer and nacreous layer were identified,which are characterized by prismatic structure and stratified structure,respectively.In addition,the profile can be subdivided into two parts:altered and unaltered zones.Laser inductively coupled plasma mass spectrometry(LA-ICP-MS)mapping shows that the element concentrations of the altered zones were influenced by the authigenic carbonate rocks,whereas the element concentrations of unaltered zones remain stable.In-situ X-ray diffraction(XRD)analyses show that the mineral constituent of the prismatic layer is mainly composed of aragonite.Along with the growth profile,Mg/Ca ratios of unaltered zones have minor variations,ranging 0.72-0.97 mmol/mol(mean=0.87 mmol/mol),with estimated temperatures of 3.8-4.1℃,indicating that the temperature of the surrounding seawater remains constant and agree with the measured data of 3.9℃which was conducted by a conductivity-temperature-depth system(CTD).The minor variations of Ba/Ca ratios(0.01-0.06 mmol/mol;mean=0.04 mmol/mol)indicate a relatively stabilized salinity of the surrounding seawater.S/Ca ratios show large variations of 0.04-4.15 mmol/mol(mean=1.37 mmol/mol).S/Ca ratios have regular variations which generally correspond to the variations of the Mg/Ca ratios,highlighting that the S/Ca ratios of bivalve shells show the potential to reflect the growth rate of the Gigantides.However,further studies should be carried out on the understanding of the links between the S/Ca ratios and seepage intensity of cold-seep fluids. 展开更多
关键词 Mg/Ca Ba/Ca and s/Ca ratios laser inductively coupled plasma mass spectrometry(LA-ICPMs) Gigantidas platifrons Haima cold seep south China sea
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基金业绩评估的创新指标SR——基于Sharpe指数的改进及中国基金业的实证研究
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作者 苟文峰 《西安财经学院学报》 2005年第2期70-74,共5页
Sharpe指数是目前在国内外较为流行的一种基于风险调整后的证券投资基金业绩衡量指标,但由于其模型自身的缺陷,许多学者对其进行了不断改进。本文通过改进的Sharpe指数M2方法和基于VAR的RAROC法对中国基金业绩进行实证研究,并在此基础... Sharpe指数是目前在国内外较为流行的一种基于风险调整后的证券投资基金业绩衡量指标,但由于其模型自身的缺陷,许多学者对其进行了不断改进。本文通过改进的Sharpe指数M2方法和基于VAR的RAROC法对中国基金业绩进行实证研究,并在此基础上首次提出了一个全新的综合业绩评价指标SR,其实质是将投资者的风险偏好及投资成本同时纳入对Sharpe指数进行再调整,创新地提出了Sharpe指数的风险及成本再调节因子"g。经过实证检验,基金业绩的SR指标排名具有相对稳定性,克服了单独使用Sharpe指数或RAROC法进行业绩评价的较大波动性,为基金投资者提供了一个很好的基金业绩参考指标。 展开更多
关键词 sharpe指数 综合业绩评价指标 中国 基金业 sR指标 证券投资基金 证券市场 基金管理公司 创新
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The Impact of Fabric Weave and Anisotropy on the Poisson’s Ratio in Technical Fabrics
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作者 DianaŠimićPenava Željko Penava Tea Jovanović 《Journal of Civil Engineering and Architecture》 2023年第8期373-389,共17页
Poisson’s ratio changes during the tensile stress of technical fabric samples due to the anisotropy of technical fabrics.This paper examines the effects of the type of weave and the anisotropic characteristics of the... Poisson’s ratio changes during the tensile stress of technical fabric samples due to the anisotropy of technical fabrics.This paper examines the effects of the type of weave and the anisotropic characteristics of the technical fabric on maximum tensile force,corresponding elongation,work-to-maximum force,elasticity modulus,and Poisson’s ratio when axial tensile forces are applied to samples cut at various angles in the direction of the weft yarns of the technical fabric.In the lab,3 cotton fabric samples of constant warp and weft density with different structural weave types(plain weave,twill weave,atlas weave)were subjected to the tensile force until they broke at the following angles:0°,15°,30°,45°,60°,75°,90°.Based on the different measured values of technical fabric stretching in the longitudinal direction and lateral narrowing,Poisson’s ratio is calculated.The Poisson’s ratio was calculated up to a relative elongation of the fabric of 8%,as the buckling of the fabric occurs according to this elongation value.According to the results presented in this paper,the type of weave of the fabric,the direction of tensile force,and the relative narrowing of the technical fabrics all play important roles in the Poisson’s ratio value.The Poisson’s ratio curve of a technical fabric under tensile stress(i.e.elongation)is primarily determined by its behaviour in the opposite direction of the elongation.The change in the value of the Poisson’s ratio is represented by a graph that first increases nonlinearly and then decreases after reaching its maximum value. 展开更多
关键词 WARP WEFT technical fabric weave type Poisson’s ratio tensile force
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2021年青海玛多M_(S)7.4地震前后CO异常变化研究
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作者 史延飞 辛存林 +1 位作者 梁浩东 刘海博 《地震工程学报》 CSCD 北大核心 2024年第3期692-702,723,共12页
地震前后气体地球化学信息的研究在地震监测预报中具有较高的应用价值。为研究2021年5月22日青海玛多M_(S)7.4地震与CO时空变化之间的关系,在以瓦里关大气观测站地面数据验证大气红外探测仪(AIRS)反演数据可靠性的基础上,提取玛多M_(S)... 地震前后气体地球化学信息的研究在地震监测预报中具有较高的应用价值。为研究2021年5月22日青海玛多M_(S)7.4地震与CO时空变化之间的关系,在以瓦里关大气观测站地面数据验证大气红外探测仪(AIRS)反演数据可靠性的基础上,提取玛多M_(S)7.4地震前后AIRS反演的CO数据,通过滑动均值法、差值法对玛多地震前后不同尺度的CO浓度数据进行处理和分析。结果表明:利用卫星遥感数据提取CO地球化学信息是可靠的。时间上,玛多M_(S)7.4地震前两个月CO浓度开始波动,出现峰值,地震发生后恢复平静;空间上,震中位置的CO浓度在近地面变化尤其明显,震中及附近区域的CO浓度从3月开始逐渐升高,由离散分布逐渐向震中和发震断裂带聚拢靠近,到4月底达到最大异常18.60×10^(-9),异常高值中心的连线与发震断层江错断裂走向、地表破裂分布一致。排除背景值和季节变化的影响,推断CO浓度异常变化是地震引起的,主要归因于地下气体释放和岩石挤压碰撞产气,气体逸散后在大气圈中发生的一系列化学反应起次要作用。 展开更多
关键词 青海玛多 M_(s)7.4地震 AIRs传感器 CO柱浓度 CO体积混合比
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多期Sharpe比率及在基金评价中的应用研究
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作者 顾亚芳 《无锡职业技术学院学报》 2013年第6期37-40,共4页
在我国新兴的基金投资市场中,传统夏普比率所存在的收益率正态分布局限越发渐显。文章从多期Sharpe比率角度入手,运用MVaR来衡量基金的风险水平,构建出基于MVaR调整后的多期Sharpe比率。同时,选择了国内10只封闭式基金,利用MVaR调整后... 在我国新兴的基金投资市场中,传统夏普比率所存在的收益率正态分布局限越发渐显。文章从多期Sharpe比率角度入手,运用MVaR来衡量基金的风险水平,构建出基于MVaR调整后的多期Sharpe比率。同时,选择了国内10只封闭式基金,利用MVaR调整后的多期Sharpe比率对其业绩水平进行评价,发现基金业绩水平与其投资风格、投资对象等因素有关,与投资期限长短没有明显的关联。 展开更多
关键词 多期sharpe比率 MVaR修正 基金评价
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乌什M_(S)7.1地震前地倾斜、地应变加卸载响应比异常分析
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作者 范亚玲 赵彬彬 《内陆地震》 2024年第2期151-157,共7页
基于岩石应力的本构关系,以2024年1月23日乌什M_(S)7.1地震前震中及周边500 km范围内地倾斜、地应变数据作为“响应量”,利用库伦应力触发模型的加卸载响应比方法进行计算,结果显示,乌什洞体应变等3个测项均出现震前LURR异常,这表明震... 基于岩石应力的本构关系,以2024年1月23日乌什M_(S)7.1地震前震中及周边500 km范围内地倾斜、地应变数据作为“响应量”,利用库伦应力触发模型的加卸载响应比方法进行计算,结果显示,乌什洞体应变等3个测项均出现震前LURR异常,这表明震源区介质存在明显的应力积累过程,同时也说明从倾斜、应变的潮汐频段中能够提取出地震预测的有效信息。 展开更多
关键词 加载卸载响应比(LURR) 地倾斜 地应变 乌什M_(s)7.1地震
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高热惊厥患儿外周血NLR和H_(2)S水平变化及与脑损伤的相关性
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作者 贺元平 王伟 《新疆医科大学学报》 CAS 2024年第4期553-558,共6页
目的探讨高热惊厥患儿外周血中性粒细胞/淋巴细胞比值(NLR)和硫化氢(H_(2)S)水平变化及与脑损伤的相关性。方法选取2021年1月至2023年1月期间本院收治的高热惊厥患儿共220例,其中单纯性153例纳入单纯性组,复杂性67例纳入复杂性组,同期... 目的探讨高热惊厥患儿外周血中性粒细胞/淋巴细胞比值(NLR)和硫化氢(H_(2)S)水平变化及与脑损伤的相关性。方法选取2021年1月至2023年1月期间本院收治的高热惊厥患儿共220例,其中单纯性153例纳入单纯性组,复杂性67例纳入复杂性组,同期选取高热无惊厥患儿109例纳入对照组。所有患儿均检测外周血NLR和H_(2)S水平,采用受试者工作特征(ROC)曲线鉴别单纯性及复杂性高热惊厥患儿。根据高热惊厥患儿有无脑损伤发生情况分为脑损伤组及无脑损伤组,收集两组高热惊厥患儿临床资料,采用多因素Logistic回归模型分析影响高热惊厥患儿脑损伤的独立危险因素。结果与对照组比较,单纯性组及复杂性组外周血NLR水平升高,H_(2)S水平降低(P<0.05),与单纯性组比较,复杂性组外周血NLR水平升高,H_(2)S水平降低(P<0.05)。ROC分析结果显示,外周血NLR、H_(2)S单独检测及二者联合检测鉴别单纯性及复杂性高热惊厥患儿的AUC值(95%CI)分别为0.615(0.547~0.680)、0.731(0.667~0.788)、0.827(0.771~0.875),NLR、H_(2)S联合检测的预测效能高于单独检测(Z=4.488、2.161,P<0.05)。脑损伤组惊厥时体温≥40℃、复杂性高热惊厥、惊厥发作次数≥2次、惊厥持续时间≥15 min例数占比、外周血NLR水平均高于无脑损伤组,H_(2)S水平低于无脑损伤组(P<0.05)。多因素Logistic回归模型分析结果显示,复杂性高热惊厥、惊厥发作次数≥2次,惊厥持续时间≥15 min、外周血NLR高水平及H_(2)S低水平是影响高热惊厥患儿发生脑损伤的独立危险因素(P<0.05)。结论高热惊厥患儿外周血NLR水平升高,H_(2)S水平降低,外周血NLR、H_(2)S水平对于高热惊厥患儿分型具有重要的鉴别价值,且与高热惊厥患儿脑损伤的发生密切相关。 展开更多
关键词 高热惊厥 脑损伤 中性粒细胞/淋巴细胞比值(NLR) 硫化氢(H_(2)s)
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脐动脉血流S/D值联合孕妇血清CX3CL1 HIF-1α对胎儿窘迫的诊断价值
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作者 许旭 王书萍 江楠 《安徽医学》 2024年第4期458-462,共5页
目的探讨脐动脉血流收缩期末最大血流速度/舒张期末最大血流速度(S/D)、血清趋化因子C-X3-C配体1(CX3CL1)、血清缺氧诱导因子-1α(HIF-1α)对胎儿窘迫(FD)的诊断价值。方法选取2020年5月至2022年5月在青岛市妇女儿童医院妇产科分娩且出... 目的探讨脐动脉血流收缩期末最大血流速度/舒张期末最大血流速度(S/D)、血清趋化因子C-X3-C配体1(CX3CL1)、血清缺氧诱导因子-1α(HIF-1α)对胎儿窘迫(FD)的诊断价值。方法选取2020年5月至2022年5月在青岛市妇女儿童医院妇产科分娩且出现FD的128例孕妇为研究对象(FD组),根据新生儿Apgar评分将FD孕妇分为轻度窘迫组74例和重度窘迫组54例,另取同期在本院定期产检并分娩的健康且未出现FD的孕妇78例为正常组;超声检测FD孕妇脐动脉血流S/D值;ELISA法检测FD孕妇血清CX3CL1、HIF-1α水平;Pearson法分析FD孕妇血清CX3CL1、HIF-1α水平与脐动脉血流S/D值的相关性;受试者工作特征(ROC)曲线分析血清CX3CL1、HIF-1α水平及脐动脉血流S/D值对胎儿重度窘迫的诊断价值。结果FD组孕妇脐动脉血流阻力指数(RI)、搏动指数(PI)、S/D值、血清CX3CL1及HIF-1α水平均显著高于正常组(P<0.05),重度窘迫组孕妇RI值、PI值、S/D值、血清CX3CL1及HIF-1α水平均高于轻度窘迫组(P<0.05)。FD组血清CX3CL1、HIF-1α与脐动脉血流S/D值均呈正相关(r=0.531、0.489,P<0.05)。脐动脉血流S/D值、血清CX3CL1、HIF-1α以及3项联合诊断胎儿重度窘迫的AUC分别为0.870、0.802、0.731、0.941,联合诊断的灵敏度为87.04%,特异度为90.54%,3项联合优于脐动脉血流S/D值、血清CX3CL1、HIF-1α各自单独诊断(Z3项联合-S/D=2.775、Z3项联合-CX3CL1=3.998、Z3项联合-HIF-1α=4.925,P均<0.05)。结论FD孕妇脐动脉血流S/D值、血清CX3CL1、HIF-1α水平均上升,且血清CX3CL1、HIF-1α水平与脐动脉血流S/D值均呈正相关,3项联合对诊断胎儿重度窘迫有更高的价值。 展开更多
关键词 胎儿窘迫 脐动脉血流s/D值 趋化因子C-X3-C配体1 缺氧诱导因子-1Α
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红细胞比容、血流S/D比值及同型半胱氨酸在妊娠期糖尿病患者中的表达及对妊娠结局的影响
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作者 冯宗玉 叶丽娥 《医师在线》 2024年第5期44-46,共3页
目的探究红细胞比容、血流S/D比值及同型半胱氨酸在妊娠期糖尿病患者中的表达及对妊娠结局的影响。方法选取我院2021年1月~2023年1月纳入的86例妊娠期糖尿病患者为研究组,另外选取同时期86例妊娠期健康孕妇作为对照组,分别对两组孕妇以... 目的探究红细胞比容、血流S/D比值及同型半胱氨酸在妊娠期糖尿病患者中的表达及对妊娠结局的影响。方法选取我院2021年1月~2023年1月纳入的86例妊娠期糖尿病患者为研究组,另外选取同时期86例妊娠期健康孕妇作为对照组,分别对两组孕妇以及研究组不同疾病严重程度孕妇之间的红细胞比容、血流S/D比值、同型半胱氨酸表达水平进行比较,观察记录两组孕妇不良妊娠结局的发生情况。结果研究组孕妇的红细胞比容明显低于对照组,血流S/D比值及同型半胱氨酸表达水平均明显高于对照组,差异有统计学意义(P<0.05);轻度、中度、重度妊娠期糖尿病患者的红细胞比容、血流S/D比值及同型半胱氨酸水平存在明显差异,且随着疾病严重程度的增高,红细胞比容越低,血流S/D比值及同型半胱氨酸水平越高,差异有统计学意义(P<0.05);研究组孕妇的不良妊娠结局总发生率明显高于对照组,差异有统计学意义(P<0.05)。结论红细胞比容、血流S/D比值及同型半胱氨酸在妊娠期糖尿病患者中的表达水平异于健康孕妇,同时还与孕妇的妊娠结局存在一定的关联,血流S/D比值及同型半胱氨酸较高水平的表达与红细胞比容较低的情况增加了妊娠期糖尿病孕妇不良妊娠结局的发生率。 展开更多
关键词 红细胞比容 血流s/D比值 同型半胱氨酸 妊娠期糖尿病 妊娠结局
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