Real-time prediction of mechanical behaviors of underwater shield tunnel structure using machine learning method based on structural health monitoring data

Predicting the mechanical behaviors of structure and perceiving the anomalies in advance are essential to ensuring the safe operation of infrastructures in the long run.In addition to the incomplete consideration of influencing factors,the prediction time scale of existing studies is rough.Therefore,this study focuses on the development of a real-time prediction model by coupling the spatio-temporal correlation with external load through autoencoder network(ATENet)based on structural health monitoring(SHM)data.An autoencoder mechanism is performed to acquire the high-level representation of raw monitoring data at different spatial positions,and the recurrent neural network is applied to understanding the temporal correlation from the time series.Then,the obtained temporal-spatial information is coupled with dynamic loads through a fully connected layer to predict structural performance in next 12 h.As a case study,the proposed model is formulated on the SHM data collected from a representative underwater shield tunnel.The robustness study is carried out to verify the reliability and the prediction capability of the proposed model.Finally,the ATENet model is compared with some typical models,and the results indicate that it has the best performance.ATENet model is of great value to predict the realtime evolution trend of tunnel structure.

Genome-wide identification,characterization and functional prediction of the SRS gene family in sesame(Sesamum indicum L.)

Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants that contain RING-like zinc finger domain and are associated with the regulation of several physiological and biochemical processes.They also play vital roles in plant growth and development such as root formation,leaf development,floral development,hormone biosynthesis,signal transduction,and biotic and abiotic stress responses.Nevertheless,the SRS gene family was not reported in sesame yet.In this study,identification,molecular characterization,phylogenetic relationship,cis-acting regulatory elements,protein-protein interaction,syntenic relationship,duplication events and expression pattern of SRS genes were analyzed in S.indicum.We identified total six SiSRS genes on seven different linkage groups in the S.indicum genome by comparing with the other species,including the model plant Arabidopsis thaliana.The SiSRS genes showed variation in their structure like2–5 exons and 1–4 introns.Like other species,SiSRS proteins also contained‘RING-like zinc finger'and‘LRP1'domains.Then,the SiSRS genes were clustered into subclasses via phylogenetic analysis with proteins of S.indicum,A.thaliana,and some other plant species.The cis-acting regulatory elements analysis revealed that the promoter region of SiSRS4(SIN_1011561)showed the highest 13 and 16 elements for light-and phytohormone-responses whereas,SiSRS1(SIN_1015187)showed the highest 15 elements for stress-response.The ABREs,or ABA-responsive elements,were found in a maximum of 8 copies in the SiSRS3(SIN 1009100).Moreover,the available RNA-seq based expression of SiSRS genes revealed variation in expression patterns between stress-treated and non-treated samples,especially in drought and salinity conditions in.S.indicum.Two SiSRS genes like SiSRS1(SIN_1015187)and SiSRS5(SIN_1021065),also exhibited variable expression patterns between control vs PEG-treated sesame root samples and three SiSRS genes,including SiSRS1(SIN_1015187),SiSRS2(SIN_1003328)and SiSRS5(SIN_1021065)were responsive to salinity treatments.The present outcomes will encourage more research into the gene expression and functionality analysis of SiSRS genes in S.indicum and other related species.

An Overview of the Achievements of Modern Research on the Flying Shadow Pavilion Pictorial

The current academic research on the Dian Shi Zhai Pictorial founded in 1884 has been perfected,but there is very little research on the Flying Shadow Pavilion Pictorial,which can be said to be derived from Dian Shi Zhai Pictorial terms of both content and form,and which was founded by the Haiist painter Wu Youru in 1890 in order to reward the increasing number of admirers,but it is still in the initial stage.Flying Shadow Pavilion Pictorial consisted of four parts:pictures of ladies in Shanghai costumes,news about current affairs,pictures of animals,and compilations of women,each of which was accompanied by the then popular notebooks,which were popular at the time among the then readers because of the matching of pictures with text and the mixing of narratives and discussions.This paper takes Flying Shadow Pavilion Pictorial as the main object,summarizes the existing literature about Flying Shadow Pavilion Pictorial,points out the deficiencies of the current research on this basis,and points out the development trend of Flying Shadow Pavilion Pictorial in the future research.

A Network Pharmacology Study on the Effects of Ma Xing Shi Gan Decoction on Influenza

Objective Pharmacological methods were used to screen targets and signaling pathways of Ma Xing Shi Gan Decoction(MXSGD)during influenza treatments,and mechanisms underlying antiinfluenza effects were elucidated.Methods The Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)and relevant literature were searched under predefined conditions to identify the main compounds and their targets.Interactions between the target proteins were predicted using the STRING database.Gene Ontology(GO)functional enrichment analyses and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analyses were performed on the core targets involved in the influenza protein-protein interaction(PPI)network,using WebGestalt and the reactome database.iGEMDOCK was used for molecular docking of receptors and ligands to produce docking scores,and the results were visualized using Autodock and PyMOL.Results In total,126 major compounds and their respective targets were screened.355 influenza target proteins and 1221 influenza protein interactions were predicted using the STRING database.Influenza-related signaling pathways were strongly enriched in pharmacodynamic targets of MXSGD such as cytokine signaling in immune system and signaling by interleukin.The main biological process was response to the stimulates.Molecular docking results showed that RELALicochalcone A docking elicited by MXSGD,was superior to that of other target proteins and active compounds,suggesting that the docking site is also the main effector site of MXSGD during influenza treatments.Conclusions The results showed that MXSGD exerts antiinfluenza effects by interfering with virus adsorption,inhibiting virus proliferation,influencing immune functions and protecting host cells,which may prevent inflammation-induced tissue damage.

A Comparative Study of Two Spanish Versions of the Poem Junzi Xielao of Shi Jing

The purpose of this paper is to do a comparative study of two complete Spanish versions of Shi Jing with a detailed analysis of the poem Junzi Xielao.The culture and personal backgrounds of the two translators,their translation purposes and intended readers largely influenced the translating style and technique of the two versions.

Systematic Pharmacological Strategies to Explore the Regulatory Mechanism of Ma Xing Shi Gan Decoction on COVID-19

Objective To use systematic pharmacological strategies to explore the regulatory mechanisms of Ma Xing Shi Gan Decoction(MXSGD)against the coronavirus disease 2019(COVID-19).Methods Data on the compounds and targets of MXSGD were collected from the Traditional Chinese Medicene Systems Parmacology Database and Analysis Platform(TCMSP)and TCM Databases@Taiwan.Data on ACE2-related targets and the protein-protein interaction(PPI)were collected from the String database.The Cytoscape 3.7.2 was used to construct and analyze the networks.The DAVID platform was used for Gene Ontology(GO)and pathway enrichment analyses.Results Data on 272 MXSGD targets and 21 SARS-CoV-2 potential targets were collected.Four networks were constructed and analyzed based on the data:(1)compound-target network of MXSGD;(2)MXSGD-SARS-CoV-2-PPI network;(3)cluster of MXSGD-SARS-CoV-2-PPI network;(4)Herb-Pathway-Target network.The core targets included AKT1,MAPK3,IL-6,TP53,VEGFA,TNF,CASP3,EGFR,EGF and MAPK1.The antiviral biological processes were inflammatory responses(inflammatory cells,inflammatory cytokines and their signaling pathways),immune responses(T cells,monocytes,B cells and other immune cells),immune factors(IFN-γ,TNF-αand so on),virus defense,humoral immunity and mucosal innate immune response.The antivirus-related signaling pathways included TNF,NOD-like receptor,FoxO,PI3K-AKT and Toll-like receptor signaling pathways.Conclusions MXSGD can control disease progression by regulating multiple compounds and targets;it can reduce inflammation and balance immunity by regulating several proteins that interact with ACE2 and signaling pathways closely related to disease development.

Review: Hu Houxuan, "Xia and the Tu State in the Oracle Inscriptions: A Consideration" Gudai Chengbang Shi Yanjiu (Studies on Ancient City States) Renmin Press, 1989, Pp. 340-353.

This article verified that the Tu state mentioned in the oracle inscriptions was the Xia people after the Xia Dynasty had been conquered by Tang, the first king of the Shang Dynasty m c.a. 16th century B.C. The state of Xia, which originated from Yu, was entitled "Xia Hou"; its king was hence called "Xia Hou Di" (Emperor of Xia Hou), e.g."Xia Hou Di Qi". The Xia people, together with the Yin (Shang) people, and the Zhou people, were the so-called "people of San Dai" (Three Dynasties). As mentioned in "Lunyu, Bayi", they founded the states, with the Xia people being associated with the pine, the Yin people with the cypress, and the Zhou people with the chestnut.

An Analysis of Tree English Translations of “To the Tune of ‘Water Dragon Song^1’” by Su Shi

Su Shi is known for his poems of haofang style as well as wanyue style. The author takes a comparative reading of three English renderings of"Water Dragon Song"; both achievements and problems in each version are discussed regarding imagery, meaning, poet's sentiments and poetic atmosphere, for the purpose of working out a better rendering.

李时珍（Li Shi Zhen，1518-1593）中国医学家和药物学家（Hakeem and Pharmacologist，China）

李时珍，字东璧，号濒湖，蕲州（今湖北省蕲春县）人。世业医。继承家学，更重视药物研究。通过实物考察和深入民间采访，并参考历代医药等文献800余种，历时27年写成《本草纲目》。收入各种药物1892种，插图1100余幅，附处方10000多条，总结了16世纪以前中国民间丰富的药物经验，对后世药物学发展有重大的贡献。在疗效方面重视临床实践，如对大枫子治麻风、土茯苓治梅毒等有新的结论。

An Example of the Scientists—Congratulate Professor SHI Changxu on His Seventyth Birthday

November 15 is the seventyth anniver-sary of Prof.SHI Changxu(C.H.Shih),honorary director of the Institute of MetalResearch,Academia Sinica.As a memberof Chinese Academy of Sciences and direc-tor of the First Division of Technical Sci-ence,Academia Sinica,vice president ofthe National Natural Science Foundation ofChina,and editor-in-chief of ActaMetallurgica Sinica,Prof.Shi is learnedand distinguished in his study,and showsenergy and initiative in his work.And he isextremely loyal and devoted to his countryand his people,so that he commands ourdeep respect and sets an example to the

New Interpretation on“Qin Bu Shi(寝不尸)”in The Analects of Confucius

“When sacrifices are to be offered to ancestors,Shi(尸)is indispensable.This ceremonial convention has been kept intact in the dynasties of Yu,Xia,Shang and Zhou.”Shi refers to a person alive in place of the deceased to be sacrificed.Shi is required to stand in the sacrificial ceremony in Xia dynasty,which is called the standing Shi,while in dynasties of Shang and Zhou,Shi is supposed to be seated,calling the sitting Shi.The sitting posture of Shi at the sacrificial ritual then is different considerably from the way we sit on the buttocks today.Shi is expected to sit on the knees.Specifically,Shi should keep a kneeling position,with knees on the ground and buttocks on the heels whilst his head bowing and his back arching.Accordingly,Qin Bu Shi(寝不尸)in The Analects of Confucius should be interpreted as one should not bother to adopt the sitting Shi posture while retiring to bed,rather than the version,as has been annotated by Yang Bojun,“Confucius does not sleep(lying stretched out)like a dead body.”

Minister Shi Dazhen Answers the Reporters' (of Britain "Financial Times") Questions

On June 3 1996, Minister of Electric Power Shi Dazhen accepted news-covering of Britain "Financial Times" resident reporter in Beijing Tony Walker, resident reporter in Hong Kong John Ridding and Asian Editor Peter Montagnon, and answered their questions in the aspects of the 9th Five-year Development Planning of China’s Electric Power and some related issues.

An interview with Shi Guangsheng

A short time ago, Yang Lan, hostess of the Hong Kong Phoenix Cable TV, interviewed Shi Guangsheng, minister of foreign trade and economic cooperation, on China’s economic growth and foreign trade situation.

On Beijing Dialect Translation from the Perspective of Domestication and Foreignization --A Case Study of Shi Xiaojing＇ s English Version of Luotuo Xiangzi

In Lao She＇s works, the use of the Beijing dialect has a strong local characteristic, and readers can fully appreciate the essence of old Beijing＇ s flavor. His famous work Luotuo Xiangzi has embodied the characteristics of Beijing, that is why it is popular among both the public and mmslators. Threrfore, it is significant to study the English translation of Luotuo Xiangzi. Shi Xiaojing has the background of living abroad, and she has also been influenced by Chinese culture. So, her translation ofLuotuo Xiangzi is worth analyzing. This paper will analyze some examples of Beijing dialect in Shi Xiaojing＇s English Version of Luotuo Xiangzi by using the theory of domestication and foreignization to make a summary and to identify deficiencies.

Shi Mingxian──Academician of the Chinese Academy of Engineering

ＳｈｉＭｉｎｇｘｉａｎ──ＡｃａｄｅｍｉｃｉａｎｏｆｔｈｅＣｈｉｎｅｓｅＡｃａｄｅｍｙｏｆＥｎｇｉｎｅｅｒｉｎｇＳｈｉＭｉｎｇｘｉａｎｗａｓｂｏｒｎｉｎＣｈａｎｇｓｈｕ，Ｊｉａｎｇｓｈｕｐｒｏｖｉｎｃｅｉｎ１９３３，ａｎｄｇｒａｄｕａｔｅｄａｓａｐｏ...

老官山汉墓天回医简《治六十病和齐汤法》含细辛方剂组方配伍规律研究

目的:探讨老官山汉墓天回医简《治六十病和齐汤法》含细辛方剂组方配伍规律。方法:运用文献学方法,对本书含细辛方组成药物进行考证、梳理;通过分类统计各药物使用频次、频率等,结合方剂主治,对含细辛方组方配伍规律进行总结、提炼。结果:本书15首含细辛方共配伍药物39味,累计运用92次;其中使用频次最多的三味药为蜀椒与桂各11次、姜9次。按功效分类,与细辛配伍使用最多的为温里药,其使用总频次为41次;使用频率排第二的药类为化痰药、补虚药和清热药,各使用7次。按药性分类,与细辛配伍使用药物药性以温热类药物为主,共使用63次。结论:本书含细辛方配伍规律是以同类药物相辅相成运用为主,异类药物相反相成运用为辅。“细辛-花椒-桂-姜”的配伍结构辛温散寒、通痹止痛,既切中病机,又针对症状,是本书细辛方以同类药物相辅相成运用为主的配伍规律的体现。