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Monolithic Integration of a Widely Tunable Laser with SOA Using Quantum-Well Intermixing
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作者 刘泓波 赵玲娟 +5 位作者 阚强 潘教青 王路 朱洪亮 周帆 王圩 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第9期1657-1660,共4页
This paper presents an SG-DBR with a monolithically integrated SOA fabricated using quantum-well intermixing (QWI) for the first time in China's Mainland. The wavelength tuning range covers 33nm and the output p... This paper presents an SG-DBR with a monolithically integrated SOA fabricated using quantum-well intermixing (QWI) for the first time in China's Mainland. The wavelength tuning range covers 33nm and the output power reaches 10mW with an SOA current of 50mA. The device can work at available channels with SMSR over 35dB. 展开更多
关键词 tunable laser semiconductor-optical-amplifier ion implantation quantum-well intermixing
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An Integratable Distributed Bragg Reflector Laser by Low-Energy Ion Implantation Induced Quantum Well Intermixing
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作者 张靖 陆羽 +4 位作者 赵玲娟 周帆 王宝军 王鲁峰 王圩 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2004年第8期894-897,共4页
An integratable distributed Bragg reflector laser is fabricated by low energy ion implantation induced quantum well intermixing.A 4 6nm quasi continuous wavelength tuning range is achieved by controlling phase curr... An integratable distributed Bragg reflector laser is fabricated by low energy ion implantation induced quantum well intermixing.A 4 6nm quasi continuous wavelength tuning range is achieved by controlling phase current and grating current simultaneously,and side mode suppression ratio maintains over 30dB throughout the tuning range except a few mode jump points. 展开更多
关键词 photonic integrated circuit distributed Bragg reflector laser quantum well intermixing wavelength tuning
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Quantum Well Intermixing of InGaAsP QWs by Impurity Free Vacancy Diffusion Using SiO_2 Encapsulation
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作者 张靖 陆羽 王圩 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2003年第8期785-788,共4页
Experiment on quantum well intermixing (QWI) of InGaAsP QWs by impurity free vacancy diffusion (IFVD) using SiO 2 encapsulation is reported.A maximum band gap wavelength blue shift as large as 200nm is realized.Furt... Experiment on quantum well intermixing (QWI) of InGaAsP QWs by impurity free vacancy diffusion (IFVD) using SiO 2 encapsulation is reported.A maximum band gap wavelength blue shift as large as 200nm is realized.Furthermore,an FP laser blue shifted 21nm by QWI is fabricated with characteristics comparable with the as grown one. 展开更多
关键词 photonic integrated circuit quantum well intermixing IFVD wavelength blue shift
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Si-Ge异质结基区BMHMT三端特性的器件模拟
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作者 毛陆虹 郭维廉 +2 位作者 陈培毅 牛萍娟 沙亚男 《微电子学》 CAS CSCD 北大核心 2000年第3期141-143,共3页
在常规混合模式晶体管的基础上 ,提出了一种新的器件结构—— Si- Ge异质结基区 Bi-MOS混合模式晶体管 ( BMHMT)。由于基区采用禁带宽度较窄的 Si- Ge合金材料 ,引起空穴向发射区反注入的势垒提高 ,这样 ,一方面减小了空穴电流 IB,提高... 在常规混合模式晶体管的基础上 ,提出了一种新的器件结构—— Si- Ge异质结基区 Bi-MOS混合模式晶体管 ( BMHMT)。由于基区采用禁带宽度较窄的 Si- Ge合金材料 ,引起空穴向发射区反注入的势垒提高 ,这样 ,一方面减小了空穴电流 IB,提高了注入效率 ;同时又增大了迁移率 ,从而提高特征频率。因此 ,这种器件具有 β高、基区电阻低。 展开更多
关键词 混合模式晶体管 si-ge异质结 三端特性 BMHMT
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Wavelength Tuning in Two-Section Distributed Bragg Reflector Laser by Selective Intermixing of InGaAsP-InGaAsP Quantum Well Structure
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作者 陆羽 张靖 +5 位作者 王圩 朱洪亮 周帆 王保军 张静媛 赵玲娟 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2003年第9期903-906,共4页
The two-section tunable ridge waveguide distribu ted Bragg reflector (DBR) laser fabricated by the selective intermixing of an InGaAsP-InGaAsP quantum well structure is presented.The threshold current of the laser is ... The two-section tunable ridge waveguide distribu ted Bragg reflector (DBR) laser fabricated by the selective intermixing of an InGaAsP-InGaAsP quantum well structure is presented.The threshold current of the laser is 51mA.The tunable range of the laser is 4.6nm,and the side mode suppress ion ratio (SMSR) is 40dB. 展开更多
关键词 tunable laser DBR laser quantum well intermixing MOCVD
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Plasma-enhanced Chemical Vapordeposition SiO_2 Film after Ion Implantation Induces Quantum Well Intermixing 被引量:1
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作者 彭菊村 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2006年第4期105-107,共3页
A method of QWI ( quantum well intermixing) realizing through plasma-enhanced chemical vapordepositiom (PECVD) SiO2 film following ion implantation was investigated. PECVD 200 mn SiO2 film after 160 keV phosphorus... A method of QWI ( quantum well intermixing) realizing through plasma-enhanced chemical vapordepositiom (PECVD) SiO2 film following ion implantation was investigated. PECVD 200 mn SiO2 film after 160 keV phosphorus(P) ion implantation was performed to induce InP-based multiple-quantum-well (MQW) laser structural intermixing, annealing process was carried out at 780 ℃ for 30 seconds under N2 flue, the blue shift ofphotoluminescenee (PL) peak related to implanted dose : 1 × 10^11, 1 × 10^12, 1×10^13 ,3 × 10^13 , 7× 10^13 ion/ cm^2 is 22 nm, 65 nm, 104 nm, 109 nm, 101 nm, respectively. Under the same conditions, by comparing the blue shift of PL peak with P ion implantation only, slight differentiation between the two methods was observed, and results reveal that the defects in the implanting layers generated by ion implantation are much more than those in SiO2 film. So, the blue shift results mainly from ion implantation. However, SiO2 film also may promote the quantum well intermixing. 展开更多
关键词 quantum well intermixing P ion implantation PECVD SiO2 PL blue shift
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Research on quantum well intermixing of 680 nm AlGaInP/GaInP semiconductor lasers induced by composited Si-Si_(3)N_(4) dielectric layer 被引量:3
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作者 Tianjiang He Suping Liu +4 位作者 Wei Li Cong Xiong Nan Lin Li Zhong Xiaoyu Ma 《Journal of Semiconductors》 EI CAS CSCD 2022年第8期46-52,共7页
The optical catastrophic damage that usually occurs at the cavity surface of semiconductor lasers has become the main bottleneck affecting the improvement of laser output power and long-term reliability.To improve the... The optical catastrophic damage that usually occurs at the cavity surface of semiconductor lasers has become the main bottleneck affecting the improvement of laser output power and long-term reliability.To improve the output power of 680 nm AlGaInP/GaInP quantum well red semiconductor lasers,Si-Si_(3)N_(4)composited dielectric layers are used to induce its quantum wells to be intermixed at the cavity surface to make a non-absorption window.Si with a thickness of 100 nm and Si_(3)N_(4)with a thickness of 100 nm were grown on the surface of the epitaxial wafer by magnetron sputtering and PECVD as diffusion source and driving source,respectively.Compared with traditional Si impurity induced quantum well intermixing,this paper realizes the blue shift of 54.8 nm in the nonabsorbent window region at a lower annealing temperature of 600 ℃ and annealing time of 10 min.Under this annealing condition,the wavelength of the gain luminescence region basically does not shift to short wavelength,and the surface morphology of the whole epitaxial wafer remains fine after annealing.The application of this process condition can reduce the difficulty of production and save cost,which provides an effective method for upcoming fabrication. 展开更多
关键词 high power semiconductor laser rapid thermal annealing composited dielectric layer quantum well intermixing optical catastrophic damage nonabsorbent window
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InGaAsP/InP Double Quantum Well Intermixing Induced by Phosphorus Ion Implantation 被引量:2
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作者 CHEN Jie ZHAO Jie +1 位作者 WANG Yong-chen HAN De-jun 《Semiconductor Photonics and Technology》 CAS 2005年第4期217-220,共4页
A quantum well intermixing(QW1) investigation on double quantum well(DQW) structure with two different emitting wavelength caused by phosphorus ion implantation and following rapid thermal annealing (RTA) was ca... A quantum well intermixing(QW1) investigation on double quantum well(DQW) structure with two different emitting wavelength caused by phosphorus ion implantation and following rapid thermal annealing (RTA) was carried out by means of photoluminescence(PL). The ion implantation was performed at the energy of 120 keV with the dose ranging from 1 × 10^11cm^-2 to 1× 10^14cm^-2. The RTA was performed at the temperature of 700 ℃ for 30 s under pure nitrogen protection. The PL measurement implied that the band gap blue-shift from the upper well increases with the ion dose faster than that from lower well and the PL peaks from both QWs remained well separated under the lower dose implantation(-1 × 10^11cm^-2) indicating that the implant vacancy distribution affects the QWl. When the ion dose is over - 1 × 10^12cm^-2, the band gap blue-shift from both wells increases with the ion dose and finally the two peaks merge together as one peak indicating the ion implantation caused a total intermixing of both quantum wells. 展开更多
关键词 Ion implantation l InGaAsP/InP DOuble quantum well(DQW) Quantum well intermixing
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Monolithic integration of electroabsorption modulators and tunnel injection distributed feedback lasers using quantum well intermixing
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作者 汪洋 潘教青 +2 位作者 赵玲娟 朱洪亮 王圩 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第12期328-333,共6页
Electroabsorption modulators combining Franz-Keldysh effect and quantum confined Stark effect have been mono-lithically integrated with tunnel-injection quantum-well distributed feedback lasers using a quantum well in... Electroabsorption modulators combining Franz-Keldysh effect and quantum confined Stark effect have been mono-lithically integrated with tunnel-injection quantum-well distributed feedback lasers using a quantum well intermixing method. Superior characteristics such as extinction ratio and temperature insensitivity have been demonstrated at wide temperature ranges. 展开更多
关键词 electroabsorption modulator tunnel injection wide temperature range operation quantum well intermixing
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A Calorimetric Study Assisted with First Principle Calculations of Specific Heat for Si-Ge Alloys within a Broad Temperature Range
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作者 王庆 王海鹏 +2 位作者 耿德路 李明星 魏炳波 《Chinese Physics Letters》 SCIE CAS CSCD 2018年第12期37-40,共4页
Calorimetric measurements are performed to determine the specific heat of Si-xat.% Ge(where x = 0, 10, 30,50, 70, 90 and 100) alloys within a broad temperature range from 123 to 823 K. The measured specific heat incre... Calorimetric measurements are performed to determine the specific heat of Si-xat.% Ge(where x = 0, 10, 30,50, 70, 90 and 100) alloys within a broad temperature range from 123 to 823 K. The measured specific heat increases dramatically at low temperatures, and the composition dependence of specific heat is evaluated from the experimental results. Meanwhile, the specific heat at constant volume, the thermal expansion, and the bulk modulus of Si and Ge are investigated by the first principle calculations combined with the quasiharmonic approximation. The negative thermal expansion is observed for both Si and Ge. Furthermore, the isobaric specific heat of Si and Ge is calculated correspondingly from OK to their melting points, which is verified by the measured results and accounts for the temperature dependence in a still boarder range. 展开更多
关键词 Ge Si A Calorimetric Study Assisted with First Principle Calculations of Specific Heat for si-ge Alloys within a Broad Temperature Range
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Si-Ge核壳纳米线禁带宽度的形貌效应
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作者 贺言 韩太坤 +1 位作者 祁玲敏 朱伟玲 《广东石油化工学院学报》 2019年第6期68-72,共5页
基于连续介质力学和键弛豫理论等方法,从原子键长和键强的变化以及应变的角度出发研究了包括三边形、四边形、六边形和圆形等不同形貌Si纳米线的能隙。研究结果表明,表面原子,特别是顶角和棱边上的原子,对多边形纳米线能带结构会产生重... 基于连续介质力学和键弛豫理论等方法,从原子键长和键强的变化以及应变的角度出发研究了包括三边形、四边形、六边形和圆形等不同形貌Si纳米线的能隙。研究结果表明,表面原子,特别是顶角和棱边上的原子,对多边形纳米线能带结构会产生重大影响。此外,研究发现纳米线的能隙随尺寸的减少而增大,并且Ge外延层厚度的改变也可实现对能带的调控。结果与实验测量吻合较好,这也说明该理论方法的可行,可为今后分析多边形核壳纳米结构的能隙以及为Si基材料的应用提供借鉴。 展开更多
关键词 si-ge核壳纳米线 能隙 形貌效应
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Gd-Si-Ge材料为基的主动磁致冷剂及磁致冷装置与工艺
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作者 邱巨峰 《稀土信息》 1998年第11期14-14,共1页
本专利提供一种主动磁蓄热器及将Gd<sub>5</sub>(Si<sub>x</sub>Ge<sub>1-x</sub>)<sub>4</sub>(x≤0.5)材料用作磁致冷剂的致冷方法。Gd<sub>5</sub>(Si<sub>x&l... 本专利提供一种主动磁蓄热器及将Gd<sub>5</sub>(Si<sub>x</sub>Ge<sub>1-x</sub>)<sub>4</sub>(x≤0.5)材料用作磁致冷剂的致冷方法。Gd<sub>5</sub>(Si<sub>x</sub>Ge<sub>1-x</sub>)<sub>4</sub>磁致冷剂具有可逆的铁磁—反铁磁或铁磁Ⅱ-铁磁Ⅰ一级相变,并具有优异的磁热性能。对于磁蓄热器商业化应用,这种新型磁致冷剂比现有的磁致冷剂效率更高。通过调整Gd<sub>5</sub>(Si<sub>x</sub>Ge<sub>1-x</sub>)<sub>4</sub> 展开更多
关键词 致冷剂 磁致冷 蓄热器 si-ge 动磁 磁热性能 一级相变温度 二级相变温度 铁磁—反铁磁 商业化应用
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Zn杂质诱导GaInP/AlGaInP红光半导体激光器量子阱混杂的研究
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作者 何天将 刘素平 +3 位作者 李伟 林楠 熊聪 马骁宇 《光子学报》 EI CAS CSCD 北大核心 2024年第1期1-12,共12页
在GaAs基GaInP/AlGaInP单量子阱结构外延片上分别使用磁控溅射设备生长ZnO薄膜和等离子增强化学气相沉积设备生长SiO2薄膜,以ZnO介质层作为Zn杂质诱导源,采用固态扩Zn的方式对激光器进行选择性区域诱导以制备非吸收窗口来提高器件的腔... 在GaAs基GaInP/AlGaInP单量子阱结构外延片上分别使用磁控溅射设备生长ZnO薄膜和等离子增强化学气相沉积设备生长SiO2薄膜,以ZnO介质层作为Zn杂质诱导源,采用固态扩Zn的方式对激光器进行选择性区域诱导以制备非吸收窗口来提高器件的腔面光学灾变损伤阈值,从而提高半导体激光器的输出功率和长期可靠性。在580~680℃、20~60 min退火条件下对Zn杂质诱导量子阱混杂展开研究,实验发现,ZnO/SiO2或ZnO/Si3N4复合介质层的采用比单一Zn介质层的杂质诱导蓝移量大,且在680℃、30 min的条件下获得了最大55 nm的蓝移量。分析结果表明,介质层所施加的压应变会将外延片表面GaAs层中Ga原子析出,促使Zn原子进入外延层中以诱导量子阱混杂。通过测量光致发光光谱发现发光强度并没有明显下降,可为后期器件制作提供借鉴。 展开更多
关键词 半导体激光器 量子阱混杂 复合介质层 蓝移 非吸收窗口
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热处理强化铝灰-磷石膏-钢渣粉稳定钢渣-碎石互配骨料力学性能
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作者 卿三成 王昕 +5 位作者 李文岗 马丽萍 王永光 薛广海 潘社卫 吴萌 《有色金属(冶炼部分)》 CAS 北大核心 2024年第9期142-153,共12页
高速发展的规模型路基建设可消纳大宗工业固废,为此,试验利用大宗工业固废磷石膏(PG)、热闷钢渣(HBSS)、铝灰(AD)、硅酸盐水泥(PC)、天然碎石(NA)开发制备了复合水稳层材料。将PG和AD进行热处理改性,同时除去环境危害。再用改性后的PG-H... 高速发展的规模型路基建设可消纳大宗工业固废,为此,试验利用大宗工业固废磷石膏(PG)、热闷钢渣(HBSS)、铝灰(AD)、硅酸盐水泥(PC)、天然碎石(NA)开发制备了复合水稳层材料。将PG和AD进行热处理改性,同时除去环境危害。再用改性后的PG-HBSS-AD-PC复合胶凝灰浆经过优化的HBSS-NA互配骨料。结果表明,用细粒HBSS部分代替碎石,可通过增加试件密实度优化水稳层的骨料架构。160℃处理后的PG与900℃处理后的AD加入PC后,通过CaSO_(4)·0.5H_(2)O硬化、水化铝酸钙(C-A-H)及钙矾石(AFt)的生成能进一步增强水稳层力学性能,固废利用率高。 展开更多
关键词 水稳层 热处理 铝灰 磷石膏 热闷钢渣 互配骨料
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水泥基混杂自修复微胶囊的二次修复特性与机理 被引量:2
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作者 王信刚 张轩哲 +1 位作者 邹府兵 朱街禄 《功能材料》 CAS CSCD 北大核心 2023年第2期2001-2005,共5页
以水泥基混杂微胶囊为研究对象,采用环扫电镜(ESEM)、激光粒度分布仪(LA)、激光共聚焦显微镜(LSM)分别表征其微观形貌、颗粒特性和修复特征,采用强度恢复率、孔结构分析水泥基混杂微胶囊的二次修复能力。结果表明:缓释微胶囊囊壁孔洞分... 以水泥基混杂微胶囊为研究对象,采用环扫电镜(ESEM)、激光粒度分布仪(LA)、激光共聚焦显微镜(LSM)分别表征其微观形貌、颗粒特性和修复特征,采用强度恢复率、孔结构分析水泥基混杂微胶囊的二次修复能力。结果表明:缓释微胶囊囊壁孔洞分布均匀,具有缓慢释放和多次释放特点;普通微胶囊表面粗糙易破裂,具有快速释放和破裂释放特点。水泥基混杂微胶囊一次强度恢复率相比单掺缓释微胶囊提升28.72%,二次强度恢复率相比单掺普通微胶囊提升252.34%。水泥基混杂微胶囊具备快速修复能力且可以实现二次修复,二次修复主要是缓释微胶囊发挥作用。 展开更多
关键词 自修复微胶囊 混杂 水泥基材料 强度恢复率 二次修复
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多变量Si杂质诱导InGaAs/AlGaAs量子阱混杂研究
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作者 刘翠翠 林楠 +2 位作者 马骁宇 张月明 刘素平 《中国光学(中英文)》 EI CAS CSCD 北大核心 2023年第6期1512-1523,共12页
腔面光学灾变损伤是导致高功率量子阱半导体激光器阈值输出功率受限制的关键因素。通过量子阱混杂技术调整半导体激光器腔面局部区域处有源区材料的带隙宽度,形成对输出光透明的非吸收窗口,可提高激光器输出功率。本文基于InGaAs/AlGaA... 腔面光学灾变损伤是导致高功率量子阱半导体激光器阈值输出功率受限制的关键因素。通过量子阱混杂技术调整半导体激光器腔面局部区域处有源区材料的带隙宽度,形成对输出光透明的非吸收窗口,可提高激光器输出功率。本文基于InGaAs/AlGaAs高功率量子阱半导体激光器初级外延片,以外延Si单晶层作为扩散源,结合快速热退火方法开展了杂质诱导量子阱混杂研究。探索了介质层生长温度、介质层厚度、热处理温度、热处理时间等条件对混杂效果的影响。结果表明,50 nm的650℃低温外延Si介质层并结合875℃/90 s快速热退火处理可在保证光致发光谱的同时获得约57 nm的波长蓝移量。能谱测试发现,Si杂质扩散到初级外延片上的波导层是导致量子阱混杂效果显著的关键。 展开更多
关键词 半导体激光器 量子阱混杂 快速热退火 波长蓝移 光致发光谱
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纳米硼对Al/CuFe_(2)O_(4)@NC复合物点火和燃烧反应特性的影响
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作者 王为民 贾睿 +6 位作者 张笑笑 于佳 杨航 陈苏杭 蒿银伟 徐抗震 赵凤起 《火炸药学报》 EI CAS CSCD 北大核心 2023年第8期696-706,I0002,共12页
为实现纳米铝热剂复合物反应活性的调节,采用静电喷雾技术制备了一系列不同Al/B摩尔比的Al/B/CuFe_(2)O_(4)@NC复合物,并通过XRD、FT-IR、SEM、DSC、激光点火和燃烧实验对复合物的相组成、结构和铝热反应特性进行系统表征分析。DSC结果... 为实现纳米铝热剂复合物反应活性的调节,采用静电喷雾技术制备了一系列不同Al/B摩尔比的Al/B/CuFe_(2)O_(4)@NC复合物,并通过XRD、FT-IR、SEM、DSC、激光点火和燃烧实验对复合物的相组成、结构和铝热反应特性进行系统表征分析。DSC结果表明,纳米B有益于增加复合物的热释放能和提高其热稳定性,Al/B摩尔比为5/5工况下的热释放能由1138.5增至1426.9J/g,铝热反应温度随B含量的增加而提高。点火和燃烧实验发现,静电喷雾能显著增强复合物的反应活性,使其点火延迟由16ms降至10ms,燃速由3.34增至6.01cm/s;通过改变Al/B摩尔比,复合物的燃速、燃烧室压力增速和静电火花感度分别在6.01~36.36cm/s、0.05~0.17MPa/ms和61.25~11.25mJ之间可调,而当Al/B摩尔比小于5/5时,其点火和燃烧困难,表明B粉是调节复合物活性的有效添加剂。 展开更多
关键词 物理化学 亚稳态混合复合物 MICS 静电喷雾 纳米铝热剂 激光点火 燃烧反应
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Study of quantum well mixing induced by impurity-free vacancy in the primary epitaxial wafers of a 915 nm semiconductor laser
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作者 Tianjiang He Suping Liu +5 位作者 Wei Li Li Zhong Xiaoyu Ma Cong Xiong Nan Lin Zhennuo Wang 《Journal of Semiconductors》 EI CAS CSCD 2023年第10期70-76,共7页
Output power and reliability are the most important characteristic parameters of semiconductor lasers.However,catas-trophic optical damage(COD),which usually occurs on the cavity surface,will seriously damage the furt... Output power and reliability are the most important characteristic parameters of semiconductor lasers.However,catas-trophic optical damage(COD),which usually occurs on the cavity surface,will seriously damage the further improvement of the output power and affect the reliability.To improve the anti-optical disaster ability of the cavity surface,a non-absorption window(NAW)is adopted for the 915 nm InGaAsP/GaAsP single-quantum well semiconductor laser using quantum well mix-ing(QWI)induced by impurity-free vacancy.Both the principle and the process of point defect diffusion are described in detail in this paper.We also studied the effects of annealing temperature,annealing time,and the thickness of SiO_(2) film on the quan-tum well mixing in a semiconductor laser with a primary epitaxial structure,which is distinct from the previous structures.We found that when compared with the complete epitaxial structure,the blue shift of the semiconductor laser with the primary epi-taxial structure is larger under the same conditions.To obtain the appropriate blue shift window,the primary epitaxial struc-ture can use a lower annealing temperature and shorter annealing time.In addition,the process is less expensive.We also pro-vide references for upcoming device fabrication. 展开更多
关键词 catastrophic optical damage primary epitaxial structure impurity-free vacancy disordering quantum well intermixing non-absorption window
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儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的治疗经验
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作者 郑曼娜 李嘉豪 +13 位作者 李乐 谭天宝 潘静 胡超 杨纪亮 沈远超 吴慧莹 牛会林 徐涛 张晓红 陈希文 鹿连伟 邹焱 杨天佑 《中国小儿血液与肿瘤杂志》 CAS 2023年第2期113-117,共5页
目的总结治疗儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的经验。方法回顾性分析2009年5月—2019年11月在广州市妇女儿童医疗中心诊治的神经节细胞瘤及神经节神经母细胞瘤混杂型病例。采用Mann-Whitney U检验、卡方检验和费希尔精确... 目的总结治疗儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的经验。方法回顾性分析2009年5月—2019年11月在广州市妇女儿童医疗中心诊治的神经节细胞瘤及神经节神经母细胞瘤混杂型病例。采用Mann-Whitney U检验、卡方检验和费希尔精确检验进行比较各指标,采用Kaplan-Meier进行生存分析、Log-rank比较生存曲线。结果本研究共纳入88例患儿,中位年龄为54.7(13.7~192.0)个月。肿瘤原发于颈部(2例)、胸部(54例)、胸腹(2例)、腹部(24例)、盆腔(6例)。INSS分期1期、2A、2B、3期、4期分别为58例、9例、10例、9例、2例。所有患儿均接受手术切除,术中失血量中位数为50(2~4700)mL,术中输注红细胞中位数为1.(0~7)单位、输注血浆中位数为100(0~1700)mL。5例(5.7%)患儿发生了并发症。20例(22.7%)有肿瘤残留,其中11例肿瘤残留大于2cm,2例残留小于2cm,另外7例未记录具体残留组织大小。术后病理确诊神经节细胞瘤32例(36.4%),神经节神经母细胞瘤混杂型56例(63.6%)。神经节细胞瘤患儿发病年龄较神经节神经母细胞瘤混杂型患儿大[69.1(47.4~88.3)个月vs 49.6(32.1~68.9)个月,P=0.005]。中位随访时间为23.5(0.0~89.0)个月,2例(2.3%)复发、3例(3.4%)死亡、9例(10.2%)失访。术后肿瘤残留对无事件生存率及总体生存率没有显著影响(P=0.691,P=0.128)。结论神经节细胞瘤及神经节神经母细胞瘤混杂型总体治疗效果良好,手术治疗安全有效,术后肿瘤残留对临床结局可能无显著影响。 展开更多
关键词 神经节细胞瘤 神经节神经母细胞瘤混杂型 儿童 手术
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基于PHOENICS的顺序输送大落差管道混油研究 被引量:27
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作者 赵会军 张青松 +2 位作者 张国忠 周诗岽 王树立 《石油天然气学报》 CAS CSCD 北大核心 2006年第4期139-142,共4页
建立了顺序输送高差混油模型,通过计算流体力学软件PHOENICS对它进行了模拟。分析了竖直管道顺序输送油品时,密度和粘度对混油的影响,并给出了模拟结果。结果表明,密度对大落差管道顺序输送过程中层流底层的影响比较明显,不可忽略。研... 建立了顺序输送高差混油模型,通过计算流体力学软件PHOENICS对它进行了模拟。分析了竖直管道顺序输送油品时,密度和粘度对混油的影响,并给出了模拟结果。结果表明,密度对大落差管道顺序输送过程中层流底层的影响比较明显,不可忽略。研究结果对于研究我国西部地形复杂地区的顺序输送管道混油问题具有理论指导意义。 展开更多
关键词 顺序输送 混油 落差 PHOENICS
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