As an emerging molecular imaging modality,cone-beam X-ray luminescence computed tomog-raphy(CB-XLCT)uses X-ray-excitable probes to produce near-infrared(NIR)luminescence and then reconst ructs three-dimensional(3D)dis...As an emerging molecular imaging modality,cone-beam X-ray luminescence computed tomog-raphy(CB-XLCT)uses X-ray-excitable probes to produce near-infrared(NIR)luminescence and then reconst ructs three-dimensional(3D)distribution of the probes from surface measurements.A proper photon-transportation model is critical to accuracy of XLCT.Here,we presented a systematic comparison between the common-used Monte Carlo model and simplified spherical harmonics(SPN).The performance of the two methods was evaluated over several main spec-trums using a known XLCT material.We designed both a global measurement based on the cosine similarity and a locally-averaged relative error,to quantitatively assess these methods.The results show that the SP_(3) could reach a good balance between the modeling accuracy and computational efficiency for all of the tested emission spectrums.Besides,the SP_(1)(which is equivalent to the difusion equation(DE))can be a reasonable alternative model for emission wavelength over 692nm.In vivo experiment further demonstrates the reconstruction perfor-mance of the SP:and DE.This study would provide a valuable guidance for modeling the photon-transportation in CB-XLCT.展开更多
采用假设模态法对旋转运动柔性梁的动力特性进行研究，给出简化的控制模型．首先采用 Hamilton 原理和假设模态离散化方法，在计入柔性梁由于横向变形而引起的轴向变形的二阶耦合量的条件下，推导出基于柔性梁变形位移场一阶完备的一次...采用假设模态法对旋转运动柔性梁的动力特性进行研究，给出简化的控制模型．首先采用 Hamilton 原理和假设模态离散化方法，在计入柔性梁由于横向变形而引起的轴向变形的二阶耦合量的条件下，推导出基于柔性梁变形位移场一阶完备的一次近似耦合模型，然后对该模型进行简化，忽略柔性梁纵向变形的影响，给出一次近似简化模型，最后将采用假设模态离散化方法的结果与采用有限元离散化方法的结果进行了对比研究．研究中考虑了两种情况：非惯性系下的动力特性研究和系统大范围运动为未知豹动力特性研究．研究结果显示，当系统大范运动为高速时，在假设模态离散化方法中应增加模态数目，较少的模态数目将导致较大误差．一次近似简化模型能够较好地反映出系统的动力学行为，可用于主动控制设计的研究．展开更多
基金the School of Life Science and Technology of Xidian University for providing experimental data acquisition system.This work was supported by the National Natural Science Foundation of China under Grant(Nos.61372046,61401264,11571012,61601363,61640418,61572400)the Science and Technology Plan Program in Shaanxi Province of China under Grant(Nos.2013K12-20-12,2015KW-002)+2 种基金the Natural Science Research Plan Program in Shaanxi Province of China under Grant(No.2015JM6322)the Scienti¯c Research Founded by Shaanxi Provincial Education Department under Grant No.16JK1772the Scienti¯c Research Foundation of Northwest University under Grant Nos.338050018 and 338020012.
文摘As an emerging molecular imaging modality,cone-beam X-ray luminescence computed tomog-raphy(CB-XLCT)uses X-ray-excitable probes to produce near-infrared(NIR)luminescence and then reconst ructs three-dimensional(3D)distribution of the probes from surface measurements.A proper photon-transportation model is critical to accuracy of XLCT.Here,we presented a systematic comparison between the common-used Monte Carlo model and simplified spherical harmonics(SPN).The performance of the two methods was evaluated over several main spec-trums using a known XLCT material.We designed both a global measurement based on the cosine similarity and a locally-averaged relative error,to quantitatively assess these methods.The results show that the SP_(3) could reach a good balance between the modeling accuracy and computational efficiency for all of the tested emission spectrums.Besides,the SP_(1)(which is equivalent to the difusion equation(DE))can be a reasonable alternative model for emission wavelength over 692nm.In vivo experiment further demonstrates the reconstruction perfor-mance of the SP:and DE.This study would provide a valuable guidance for modeling the photon-transportation in CB-XLCT.
文摘采用假设模态法对旋转运动柔性梁的动力特性进行研究，给出简化的控制模型．首先采用 Hamilton 原理和假设模态离散化方法，在计入柔性梁由于横向变形而引起的轴向变形的二阶耦合量的条件下，推导出基于柔性梁变形位移场一阶完备的一次近似耦合模型，然后对该模型进行简化，忽略柔性梁纵向变形的影响，给出一次近似简化模型，最后将采用假设模态离散化方法的结果与采用有限元离散化方法的结果进行了对比研究．研究中考虑了两种情况：非惯性系下的动力特性研究和系统大范围运动为未知豹动力特性研究．研究结果显示，当系统大范运动为高速时，在假设模态离散化方法中应增加模态数目，较少的模态数目将导致较大误差．一次近似简化模型能够较好地反映出系统的动力学行为，可用于主动控制设计的研究．
