Correlation between the Six-Minute Walk Test and Subjective Functional Class in Patients with Heart Failure

Introduction: The Six-Minute Walk Test (6MWT) is an inexpensive method to objectively evaluate physical capacity or limitation and stratify prognosis in patients with Heart Failure (HF). Since the clinical perception of symptoms may be adapted or compromised, regular evaluation from medical interviews often fails to determine functional classification. This study aimed to assess the correlation between New York Heart Association Functional Class (NYHA-FC) and the distance walked in the 6MWT. Methods: We conducted a cross-sectional observational study that included patients with HF with reduced ejection fraction followed up at an outpatient service of a teaching hospital, from August 2018 to April 2019. Patients in NYHA-FC I, II, or III were included. We compared NYHA-FC subjectively obtained during the consultation with the 6MWT performed after medical consultation, and the correlation between these two parameters was assessed. Results: The study included 70 patients with HF, 41 (58.6%) of whom were female. The mean age was 61.2 ± 12.7 years. The most prevalent etiologies were dilated idiopathic cardiomyopathy (35.7%) followed by ischemic cardiomyopathy (25.7%). The mean ejection fraction was 34.1% ± 9.8%. The average distance walked in the 6MWT by NYHA-FC I patients was 437.8 ± 95.8 meters, NYHA-FC II 360.1 ± 96.4, and NYHA-FC III 248.4 ± 98.3. Functional class measured by the 6MWT was different than that estimated by NYHA-FC in 34 patients (48.6%), 23 (32.9%) for a higher functional class and 11 (15.7%) for a lower one (p = 0.07). Pearson’s correlation coefficient between NYHA-FC and the 6MWT was -0.55. Conclusion: There was a moderate correlation between the subjective NYHA-FC and the 6MWT. The 6MWT revealed a different classification from NYHA-FC in almost half of the patients. Among those who presented discrepancies between methods, 6MWT reclassification towards a higher functional class was more common.

Six-Minute Walk Test in Patients with Rheumatoid Arthritis

Background: The 6-minute walk test (6TC) was initially used as an instrument for assessing physical and cardiorespiratory capacity, but is currently being used to monitor treatments, and compare physical interventions and prognostic evaluation. Although already recognized as a research method in several specialties, 6TC has not been used in rheumatology. Patients with rheumatoid arthritis (RA) may have impaired functional capacity as well as increased cardiovascular mortality. An adequate functional evaluation of these patients is necessary and the 6TC may be useful in this sense. Objective: The aim of this study was to perform the 6-minute walk test in RA patients and to compare the performance with a control group. Method: A cross-sectional study was carried out in which the sample consisted of 85 women, 46 patients with rheumatoid arthritis and 39 healthy controls. A descriptive analysis of the data was performed. One-Way ANOVA methodology was used to compare the patient and control groups followed by the graphic analysis. Results: The distance walked on the 6TC by RA patients was on average 522.2 meters. In the distance control group found in the 6TC was on average 628.8 meters, the difference being statistically significant. Conclusion: In this study the distance covered in 6TC by women with RA was lower than that of healthy women of the same age.

A Study of Real-time Peak Oxygen Consumption and Six-minute Walk Test

Objectives To assess the relationship between peak oxygen consumption （PVO2） and the ambulation distance in six-minute walk test （6MWT）among the healthy subjects. Methods The 51 healthy subjects were recruited for the six-minute walk test. Data of pulmonary gas exchange breath by breath, such as VO2 , VCO2 were real-time measured with wireless remote sensing K4B2, so to study the relationship between peak oxygen uptake and the ambulation distance. Results It was noticed that there was a positive linear correlation between the ambulation distance and PVO2 （ r =0. 619, P 〈0. 001 ） in six-minute walk test. The regression equation was set up （ VO2/kg =0. 05D -6. 331, P 〈 0. 001 ）. PVO2 〉 PVCO2 ,R 〈 1 were found,which suggested that 6MWT was a test below anaerobic threshold. Conclusions There was a closely positive linear correlation between the ambulation distance and PVO2, which is safety, convenient and valuable for the evaluation of cardiopulmonary function and the treatment of cardiopulmonary rehabilitation.

An Assessment of Cardiovascular Functional Capacity of a Group of Chronic Heart Failure Patients Using the 6-Minute Walk Test in a Cameroonian Urban Setting

Background: Chronic heart failure is a public health problem worldwide. It has a high mortality rate and is accompanied by a decreased functional capacity and alteration of the quality of life. Objective: This study aimed to assess the cardiovascular functional capacity of a group of patients suffering from heart failure using the 6-minute walk test (6 MWT). Methods: This was a cross-sectional study carried out in the cardiology unit of Douala’s general hospital for 4 months. We included all eligible patients aged 18 years or more who had stable chronic heart failure and gave informed consent. Those who had an acute coronary syndrome (≤1 month), tachycardia (HR ≥ 120 bpm), high blood pressure (SBP ≥ 180 mmHg and/or DBP ≥ 100 mmHg) and reduced mobility due to orthopaedic reasons were excluded. A 6 MWT was done according to the American Thoracic Society guidelines. The 6 MWT result was considered poor for - 450 m and good for >450 m. Results: We recruited a total of 81 patients (61.7% women) with a mean age of 65.9 ± 10.6 years. The most frequent risk factor for heart failure was high blood pressure (77.8%), alcohol consumption(69.1%) and a sedentary lifestyle (53.1%). The left ventricular ejection fraction was mostly preserved (42.0%) or mildly altered (46.9). The 6 MWT results were poor in 55.6% of cases, average in 19.8% of cases and good in only 24.7% of cases. More than half (59.3%) of the participants perceived the effort as being difficult. The cardiovascular functional capacity was significantly associated with age, heart failure stage and physical activity (p Conclusion: Most patients suffering from chronic stable heart failure in the general hospital of Douala have poor cardiovascular functional capacity.

Application of Six-minute Walk Test in Heart Transplantation Patients

Objectives To analyze the six-minute walk test （6MWT） and gas exchange of 5 heart transplantation patients and to approach the variation tendency of exercise tolerance, oxygen uptake （ VO2 ） and heart rate chronotropic response. Methods 5 cases of heart transplantation patients （ age 25 - 52 years） were undertaken 6MWT 6 - 30 months after operation, synchronizing gas exchanging parameters were measured by wireless portable remote sensing K4B^2 gas analyzer, 51 normal controls were compared. Results The six-minute walk distance （6MWD） of 5 patients were （592.6 ± 26.7 ） m （558 - 625 ） m, the ascending tendency during exercise was slower, the maximum heart rates were 80% ± 6% of age-predicting maximal heart rate, lower than normal control （86%） ; the end point VO2/kg were （21.8 ± 1.4 ） mL/min · kg （ 19. 94 - 23.60） mL/min · kg. Conclusions The 6WMD and VO2 of 5 patients reached normal range, but the heart rate chronotropic response and VO2 ascending tendency were slower than those of normal controls.

Six Minute Walk Test to assess functional capacity in chronic liver disease patients

AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis.

Value of the 6 minute walk test in predicting multi vessel coronary arterial disease

The 6 minute walk test (6MWT) is well established in the clinical assessment of heart failure, pulmonary hypertension and COPD. Its value as a submaximal stress test in the risk stratification of chronic stable ischaemic syndromes is as yet not validated. 95 patients undergoing coronary angiography for assessment of chronic stable angina performed the 6MWT according to a modified protocol. The gamma correlation test indicated a moderately significant relationship between ECG changes plus symptoms at the end of the 6MWT and multi vessel coronary arterial disease. The T wave changes showed no significant correlation. Hence the 6MWT is a useful tool in the risk stratification of stable ischaemic syndromes which can be safely performed in a general ward prior to hospital discharge. It would be a useful preliminary test before planning a programme of cardiac rehabilitation.

Validation of a 2 Minute Step Test for Assessing Functional Improvement

Introduction: Although many cardiopulmonary patients require home care services, the 6-minute walk test (6MWT) is unusable in most dwellings for objectively evaluating exercise capacity because it requires a 20 - 30 meter hallway. To meet this need, we developed a 2-minute step test (2MST): stepping up and down an 8 inch step for 2 minutes (1 step = bilateral step up + step down). Purpose: Evaluate the statistical validity, reproducibility, and sensitivity of the 2MST in assessing exercise capacity. Method: We compared the heart rate, oxygen saturation and perceived exertion obtained during performance of 2MST with those obtained during the 6MWT. Results: Comparing 2MST and 6MWT in 158 subjects for validity, r = 0.925 (P Conclusion: The 2MST is valid, reproducible, sensitive, safe, well-tolerated, and is a suitable substitute for the 6MWT.

Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities

Background The relationship between the 6-minute walk test （6MWT） and pulmonary function test in stable chronic obstructive pulmonary disease （COPD） remains unclear. We evaluate the correlation of 6MWT and spirometric parameters in stable COPD with different severities. 6MWT data assessed included three variables： the 6-minute walk distance （6MWD）, 6-minute walk work （6MWORK）, and pulse oxygen desaturation rate （SPO2%）. Methods 6MWT and pulmonary function test were assessed for 150 stable COPD patients with different severities. Means and standard deviations were calculated for the variables of interest. Analysis of variance was performed to compare means. Correlation coefficients were calculated for 6MWT data with the spirometric parameters and dyspnea Borg scale. Multiple stepwise regression analysis was used to screen pulmonary function-related predictors of 6MWT data. Results The three variables of 6MWT all varied as the severities of the disease. The 6MWD and 6MWORK both correlated with some spirometric parameters （positive or negative correlation; the absolute value of r ranging from 0.34 to 0.67; P 〈0.05） in severe and very severe patients, and the SPO2% correlated with the dyspnea Borg scale in four severities （t= -0.33, -0.34, -0.39, -0.53 respectively; P 〈0.05）. The 6MWD was correlated with the 6MWORK in four severities （r=0.56, 0.57, 0.72, 0.81 respectively, P 〈0.05）, and neither of them correlated with the SPO2%. The percent of predicted forced expiratory volume in 1 second （FEV1% predicted） and residual volume to total lung capacity ratio （RV/TLC） were predictors of the 6MWD, and the maximum voluntary ventilation （MW） was the predictor of the 6MWORK. Conclusions 6MWT correlated with the spirometric parameters in severe and very severe COPD patients. 6MWT may be used to monitor changes of pulmonary function in these patients.

17~45岁肥胖门诊患者的6分钟步行试验距离参考方程研究

背景 目前6分钟步行试验(6MWT)已经被广泛用于评估肥胖人群的运动能力,并为制订干预措施提供了参考依据。国外已有研究提出了其他人群的6MWT距离参考方程,但中国17~45岁且BMI≥30 kg/m^(2)肥胖受试者的6MWT距离参考方程研究较少。目的 为17~45岁门诊肥胖受试者制订6MWT距离参考方程,并评估其影响因素。方法 根据美国胸科学会指南,前瞻性选取2022年6月—2023年9月于江苏省苏北人民医院内分泌科肥胖门诊部就诊的143名年龄17~45岁且BMI≥30 kg/m^(2)的成年人(71名男性和72名女性),进行人体测量和6MWT。采用逐步多元回归模型建立6MWT距离参考方程,将新建立的6MWT距离参考方程与现有的预测方程进行比较。结果 143名受试者的平均6MWT距离为(506.1±49.8)m,其中男性平均6MWT距离为(515.7±50.1)m,大于女性的平均6MWT距离(496.6±47.9)m(P<0.05)。在年龄段17~23岁、24~30岁、31~37岁以及38~45岁中,男性与女性6MWT距离比较,差异均有统计学意义(P<0.05)。男性受试者的体质量、BMI、最大心率(HR_(max))、心率差(ΔHR)、腰围、舒张压差(ΔDBP)、Borg量表评分差(ΔBorg)与6MWT距离相关(P<0.05),女性受试者的体质量、BMI、腰围与6MWT距离相关(P<0.05)。以步进的方法将潜在的影响因素纳入多元线性回归方程中,最终建立6MWT距离参考公式:男性y=494.463+1.414×ΔHR-3.903×BMI+0.874×HR_(max),R^(2)=0.429,女性y=670.448+0.299×ΔHR-4.342×BMI-0.195×HR_(max),R^(2)=0.312。结论 17~45岁门诊肥胖受试者中,男性的平均6MWT距离长于女性,且在不同年龄段均有显著差异。男性的体质量、BMI、HR_(max)、ΔHR、腰围、ΔDBP、ΔBorg与6MWT距离相关,女性的体质量、BMI、腰围、ΔSBP与6MWT距离相关。通过多元线性回归分析,为男性和女性分别建立了预测6MWT距离的参考方程,这些公式可能为评估个体的体能水平提供有价值的参考。

特发性肺纤维化患者免疫球蛋白A、TGF-β1、IL-6和IL-17水平变化的意义

目的分析特发性肺纤维化(IPF)患者血清中免疫球蛋白A(IgA)、转化生长因子β(TGF-β1),白介素6(IL-6)和白介素17(IL-17)表达水平,研究其在IPF患者的诊断及对病情评估中的应用价值。方法选择石家庄市第二医院、河北省中医院、河北医科大学第四医院进行治疗的IPF的38例患者为病例组,选择30例因胸痛等原因进行相关检查为健康就诊者30例为对照组,分析2组研究对象血清中IgA、TGF-β1、IL-6和IL-17水平,并测定肺功能和6 min步行试验相关指标。结果病例组患者血清IgA、TGF-β1、IL-6和IL-17水平均明显高于对照组(P<0.01);病例组患者FVC、FEV1、 FEV1/FVC和步行距离明显低于对照组,而血氧饱和度下降分数明显高于对照组,差异均有统计学意义(P<0.01),病例组血清IgA、TGF-β1、IL-6和IL-17水平与FVC、FEV1和步行距离水平均呈现明显的负相关性,和血氧饱和度下降分数呈明显的正相关性(P<0.01)。结论血清IgA、TGF-β1、IL-6和IL-17水平与IPF患者发病及肺功能等情况具有一定的相关性,可能成为判断IPF病情的诊断指标。

左卡尼汀对急性心肌梗死急诊PCI患者血清H-FABP及6MWT的影响

目的探讨急性心肌梗死（AMI）急诊PCI术后应用左卡尼汀，对血清心型脂肪酸结合蛋白（H-FABP）及近期预后的影响。方法选择AMI行急诊PCI患者102例，随机分为治疗组54例和对照组48例，实验组在急诊PCI中加用左卡尼汀3．0g＋0．9％生理盐水250mL静脉滴注，以后每日1次，连续7d以上。对照组行急诊PCI治疗及常规药物治疗。比较两组血浆H-FABP、CK-MB、cTnI水平和住院期间LVEF值，随访90d后六分钟步行试验（6MWT）距离。结果实验组术后血浆H-FABP、CK-MB、cTnI水平较对照组明显降低，LVEF高于对照组（P〈0．05），随访90d后实验组6MWT距离明显高于对照组（P〈0．05）。结论AMI急诊PCI患者补充左卡尼汀对缺血心肌细胞有保护作用，可明显改善患者的心功能。

6分钟步行试验--一种值得在社区推广的老年心脏病患者心功能评价方法

目的探讨在老年心脏病患者心功能评价中6min步行试验（6-MWT）与脑钠肽前体（pro—BNP）之间的相关性。方法选择54例无器质性心脏病的老年患者及150例按照NYHA分级心功能在Ⅱ～Ⅳ级的老年心脏病患者，测定其血pro—BNP的同时行6-MWT，研究两者的相关性。结果不同心功能分级心衰患者与对照组pro—BNP间差异均有统计学意义（P〈0.05），两组患者6min步行距离（6-MWD）间差异亦有统计学意义（P〈0．01）。心衰患者pro—BNP水平与6-MWD呈负相关（r=-0．774，P〈0.01）。结论6-MWT简便易行，与pro—BNP相关性好，是一种值得在社区卫生服务机构中推广的老年心脏病患者心功能评价方法。

中药利心Ⅰ号治疗充血性心力衰竭疗效观察——血清sICAM-1浓度及6min步行试验的影响

目的:通过对CHF患者血清sICAM-1浓度及6min步行试验的观测,观察利心Ⅰ号治疗CHF的临床疗效并探讨其作用机制。方法:选择40例CHF患者随机分为治疗组和对照组,对照组给予西药常规治疗,治疗组在常规治疗的基础上给予利心Ⅰ号口服。采用酶联免疫法检测治疗前后两组患者血清中sICAM-1浓度,参照Vera Bittner报道的方法观测两组患者6MWT在治疗前后的变化情况。结果:2组患者治疗前血清中sICAM-1浓度均升高P>0.05,两组患者治疗后血清中sICAM-1与本组治疗前比较均降低P<0.01,且治疗组较对照组降低更为明显P<0.05;2组患者6MWT与本组治疗前比较均明显改善P<0.01,且治疗组与对照组比较有显著差异P<0.05。结论:利心Ⅰ号可降低CHF患者血清sICAM-1浓度,纠正细胞因子网络的紊乱;可改善CHF患者6min步行试验距离。

有氧运动对血液透析患者6分钟步行距离及血网膜素-1的影响

目的探讨有氧运动对维持性血液透析(MHD)患者6分钟步行距离及血网膜素-1的影响。方法选取2013年12月—2014年11月天津市第五中心医院MHD(MHD组)患者89例,随机分为常规治疗组(常规组,43例)和有氧运动治疗组(有氧运动组,46例),选取50例健康体检者作为正常对照组(对照组)。有氧运动组在常规治疗基础上进行6个月的透析间期有氧运动,常规组避免任何运动干预。2组MHD患者治疗前及治疗6个月后行6分钟步行试验,测量体质量、身高及血压。检测血网膜素-1、C反应蛋白(CRP)、血常规、血生化,彩色超声心动测定心血管参数,对6分钟步行距离(6MWDs)与年龄、CRP、左室射血分数(LVEF)、血网膜素-1间进行相关分析。结果 MHD组网膜素-1、CRP均较对照组升高,LVEF较对照组下降(均P<0.01);有氧运动组经有氧运动6个月后,6MWDs、LVEF、血红蛋白及血网膜素-1较治疗前增加,并且6MWDs、LVEF、血红蛋白较常规组治疗后增加;CRP、空腹血糖、收缩压较治疗前下降,CRP、空腹血糖、收缩压亦较常规组治疗后下降;治疗前MHD患者6MWDs与年龄、CRP呈负相关,与LVEF、血网膜素-1呈正相关(r分别为-0.418、-0.229、0.252、0.234,均P<0.05)。结论有氧运动可明显增加MHD患者6MWDs、LVEF、血红蛋白及血网膜素-1,降低CRP、空腹血糖和收缩压,改善身体活动能力、心功能及微炎症状态,从而降低心血管事件的发生和死亡风险。

三级医院-社区-家庭心脏康复体系对稳定期慢性心力衰竭患者心功能和活动耐量的改善效果

目的探讨三级医院-社区-家庭心脏康复体系对稳定期慢性心力衰竭患者心功能和活动耐量的改善效果。方法将150例慢性稳定期心力衰竭患者随机分为观察组和对照组,每组75例。对照组出院后采用传统方式进行康复,观察组出院后在传统康复方式基础上采用三级医院-社区-家庭心脏康复体系一体化管理模式进行康复。比较两组患者康复治疗1年后的心功能疗效,以及康复治疗前和康复治疗1年后两组患者6分钟步行试验(6MWT)距离及代谢当量。结果康复治疗1年后,观察组心功能总有效率高于对照组,两组患者6MWT距离、代谢当量均高于治疗前,且观察组均高于对照组(均P<0.05)。结论对于稳定期慢性心力衰竭患者,采用三级医院-社区-家庭心脏康复管理体系可明显改善心功能,增加6MWT距离,提高活动耐量。

心脉隆注射液对冠心病心力衰竭病人心脏功能及血浆NT-proBNP的影响

目的评价心脉隆注射液治疗冠心病心力衰竭的疗效,并观察其对病人心脏功能及血浆N末端脑钠肽原(NT-proBNP)水平的影响。方法选取2015年—2016年南阳市中心医院心内科住院治疗的冠心病心力衰竭病人116例,釆用随机、双盲的方法将其分为治疗组和对照组,各58例。两组除了接受常规的西药规范治疗外,治疗组加用心脉隆注射液4 mL加入0.9%氯化钠溶液250 mL(或5%葡萄糖溶液250 mL)静脉输注,每日1次,疗程14 d,比较两组治疗效果,测定两组治疗前后6 min步行距离、左心室舒张末期内径(LVDd)、左心室射血分数(LVEF)及NT-proBNP水平。结果治疗后对照组及治疗组6 min步行距离、LVDd及LVEF均较治疗前明显改善(P<0.05),且治疗组中6 min步行距离、LVDd及LVEF提高幅度均高于对照组(P<0.05);两组病人血浆NT-proBNP水平均较治疗前降低(P<0.05),且治疗组NT-proBNP水平较对照组降低更显著(P<0.05)。结论冠心病心力衰竭病人在西药常规治疗基础上,加用心脉隆注射液治疗,可提高病人的活动耐量,改善病人心脏功能,降低血浆NT-proBNP水平。

运动训练对慢性心力衰竭患者运动能力及MMP-9的影响——附50例报告

目的：探讨运动训练对慢性心力衰竭（chronic heart failure，CHF）患者的运动能力及血清基质金属蛋白酶-9（matrix metallopmteinase-9，MMP-9）的影响。方法：将10例NYHA心功能Ⅱ～Ⅲ级CHF患者随机分为训练组（50例）和对照组（50例），两组均予常规抗心力衰竭药物治疗，训练组每日2次行6分钟步行训练，疗程10周。分别在入院后24小时内（治疗前）及治疗10周后进行6分钟步行试验（6-minute walking test，6-MWT）及检测血清MMP-9水平，比较2组的结果。结果：治疗10周后，训练组6-MWT的行走距离从治疗前的（220±72）m增加到（372±97）m；对照组相应为（220±76）m、（287±91）m；训练组治疗前、后的运动后的血清MMP-9分别为（184±61）μg／L、（128±36）μg／L；对照组相应为（180±59）μg／L、（154±50）μg／L；上述指标两组治疗前、后比较，差异均有统计学意义（均为P〈0．01），训练组较对照组更明显（P〈0．05～0．01）。结论：心功能Ⅱ～Ⅲ级的CHF患者采用运动训练可以增加运动耐力，并可降低患者的血清MMP-9水平，减轻心室重塑的程度而起康复作用.

充血性心力衰竭患者运动前后血浆细胞间粘附分子-1含量及临床意义

目的 探讨充血性心力衰竭(CHF)患者运动前后血浆细胞间粘附分子－1(ICAM－1)的含量变化及其意义。方法 应用双抗体夹心法测定54例充血性心力衰竭患者静息状态及六分钟步行运动后即刻CHF患者血浆ICAM－1含量。结果 运动前,CHF患者的血浆ICAM－1显著高于对照组,且含量与心功能级别密切相关;低钠组CHF患者ICAM－1含量明显高于正常血钠组(P＝0.039);运动后CHF患者ICAM－1含量较运动前明显增加(P＝0．033)。结论ICAM－1在CHF发生发展中起重要作用,且与病情严重程度相关。CHF患者运动后血浆ICAM－1显著高于正常人的现象说明CHF患者对运动的耐受性明显低于正常人。

医院-家庭肺康复训练在稳定期慢性阻塞性肺疾病患者中的临床应用

目的:探讨基于多学科协作的康复团队指导下的医院-家庭肺康复训练在稳定期慢性阻塞性肺疾病患者中的应用效果。方法:选取2018年4月-2020年12月在萍乡市人民医院呼吸内科门诊就诊的稳定期慢性阻塞性肺疾病患者60例,随机分为试验组(n=30)和对照组(n=30)。试验组由肺康复团队为其制订个性化的康复方案,按既定的流程为患者进行详细全面的健康宣教及康复指导,对照组由接诊医生对患者进行常规的宣教和康复建议。比较患者干预前及干预12周后肺功能、呼吸困难量表(MMRC)评分、症状评分、6分钟步行试验(6MWT)、日常生活活动能力评分、Beck抑郁自评问卷、观察期间急性加重次数及康复训练的依从性。结果:干预后,两组MMRC评分、6MWT、症状评分、Beek抑郁自评问卷评分及急性加重次数较干预前均改善,且试验组呼吸困难改善程度优于对照组,差异均有统计学意义(P<0.05);干预后,两组第一秒用力呼气量(FEV_(1))、用力肺活量(FVC)、日常生活活动能力量表评分较干预前无改善,差异无统计学意义(P>0.05)。试验组上、下肢训练、呼吸训练及营养治疗的依从性均高于对照组,差异均有统计学意义(P<0.05)。结论:医院-家庭肺康复训练可改善稳定期慢性阻塞性肺疾病患者呼吸困难、咳嗽、咳痰等症状及提高运动耐力、减轻焦虑状态,在提高稳定期慢性阻塞性肺疾病患者的康复依从性及改善呼吸困难症状方面更优,值得临床推广。