Aim: The aim of this study was to compare the effects of bicycle and arm ergometer exercises on physical and psychosocial functions in patients who underwent Coronary Artery Bypass Surgery. Methods: A total of 39 case...Aim: The aim of this study was to compare the effects of bicycle and arm ergometer exercises on physical and psychosocial functions in patients who underwent Coronary Artery Bypass Surgery. Methods: A total of 39 cases (35 males, 4 females) were included in the study, with 23 participants aged between 52 and 65 using bicycle ergometers and a group of 16 people who performed arm ergometers opposite. After the demographic data were recorded, physical functions of all individuals participating in the study were evaluated with a 6-minute walk test, bioimpedance analysis, HDL, LDL, Triglyceride and Total cholesterol values, and psychosocial functions were evaluated with the Beck depression scale, modified borg scale and SF 36 questionnaires before and after the training. All participants were given bicycle or arm ergometer exercises for 6 weeks, 5 sessions per week, for a total of 30 sessions. Result: When the results were examined, it was observed that there was a statistically significant increase in walking distance of the people in the bicycle ergometer group compared to the arm ergometer group (p < 0.05). In addition, it was revealed that there was a statistically significant difference in the general health parameter, which is one of the sub-parameters of SF 36, in the arm ergometer group compared to the bicycle ergometer group (p Conclusion: When we look at the results of this study, it is important in terms of revealing that bicycle and arm ergometer exercises similarly improve the physical and psychosocial functions of patients who have undergone Coronary Artery Bypass Surgery. However, it has been shown that cycling exercises are much more advantageous in improving functional capacity. Summary Statement: What is already known about this topic? 1) Walking and arm exercises are good for heart diseases. What this paper adds? 2) Demonstrated that cycling and arm ergometer exercises have curative aspects for patients undergoing Coronary Artery Bypass Surgery. The implications of this paper: 3) As a result, it has been revealed that cycling and arm ergometry techniques are good indicators in patients who have undergone Coronary Artery Bypass Surgery.展开更多
目的检测个人和社会功能量表（Personal and Social Performance scale，PSP）在抑郁症患者中的信度和效度，了解PSP在抑郁症中的适用性。方法在全国6个精神卫生中心收集84例门诊抑郁症患者。所有的病例进行PSP、Montgomery--Asberg抑...目的检测个人和社会功能量表（Personal and Social Performance scale，PSP）在抑郁症患者中的信度和效度，了解PSP在抑郁症中的适用性。方法在全国6个精神卫生中心收集84例门诊抑郁症患者。所有的病例进行PSP、Montgomery--Asberg抑郁量表（Montgomery--Asberg Depression Rating Scale，MADRS）、大体社会功能量表（Global Assessment of Functioning Scale，GAF）评定，分析PSP在抑郁症患者中的内部一致性、与GAF的一致性以及与MADRS的相关性。另外，6例抑郁症病例在首次评定后的1周进行再次评定用以PSP重测一致性的检验。结果PSP的内部一致性Cron—bachd系数为0．760，PSP总分与GAF评分具有良好的正相关（r=0．906，P〈0．01），与MADRs总分呈负相关，具有统计学意义（r=-0．652，P〈0．01），重测一致性的kappa值为0．945（n=6，P=0．01）。结论PSP是一个操作简单、稳定性高的评估工具，可用于抑郁症患者社会功能的评估。量表中d维度（冲动和攻击行为）对整个量表的权重大，在抑郁症患者中与总分相关性欠佳。展开更多
The resolution of single molecule localization imaging techniques largely depends on the precision of localization algorithms.However,the commonly used Gaussian function is not appropriate for anisotropic dipoles beca...The resolution of single molecule localization imaging techniques largely depends on the precision of localization algorithms.However,the commonly used Gaussian function is not appropriate for anisotropic dipoles because it is not the true point spread function.We derived the theoretical point spread function of tilted dipoles with restricted mobility and developed an algorithm based on an artifi cial neural network for estimating the localization,orientation and mobility of individual dipoles.Compared with fi tting-based methods,our algorithm demonstrated ultrafast speed and higher accuracy,reduced sensitivity to defocusing,strong robustness and adaptability,making it an optimal choice for both two-dimensional and threedimensional super-resolution imaging analysis.展开更多
文摘Aim: The aim of this study was to compare the effects of bicycle and arm ergometer exercises on physical and psychosocial functions in patients who underwent Coronary Artery Bypass Surgery. Methods: A total of 39 cases (35 males, 4 females) were included in the study, with 23 participants aged between 52 and 65 using bicycle ergometers and a group of 16 people who performed arm ergometers opposite. After the demographic data were recorded, physical functions of all individuals participating in the study were evaluated with a 6-minute walk test, bioimpedance analysis, HDL, LDL, Triglyceride and Total cholesterol values, and psychosocial functions were evaluated with the Beck depression scale, modified borg scale and SF 36 questionnaires before and after the training. All participants were given bicycle or arm ergometer exercises for 6 weeks, 5 sessions per week, for a total of 30 sessions. Result: When the results were examined, it was observed that there was a statistically significant increase in walking distance of the people in the bicycle ergometer group compared to the arm ergometer group (p < 0.05). In addition, it was revealed that there was a statistically significant difference in the general health parameter, which is one of the sub-parameters of SF 36, in the arm ergometer group compared to the bicycle ergometer group (p Conclusion: When we look at the results of this study, it is important in terms of revealing that bicycle and arm ergometer exercises similarly improve the physical and psychosocial functions of patients who have undergone Coronary Artery Bypass Surgery. However, it has been shown that cycling exercises are much more advantageous in improving functional capacity. Summary Statement: What is already known about this topic? 1) Walking and arm exercises are good for heart diseases. What this paper adds? 2) Demonstrated that cycling and arm ergometer exercises have curative aspects for patients undergoing Coronary Artery Bypass Surgery. The implications of this paper: 3) As a result, it has been revealed that cycling and arm ergometry techniques are good indicators in patients who have undergone Coronary Artery Bypass Surgery.
文摘目的检测个人和社会功能量表（Personal and Social Performance scale，PSP）在抑郁症患者中的信度和效度，了解PSP在抑郁症中的适用性。方法在全国6个精神卫生中心收集84例门诊抑郁症患者。所有的病例进行PSP、Montgomery--Asberg抑郁量表（Montgomery--Asberg Depression Rating Scale，MADRS）、大体社会功能量表（Global Assessment of Functioning Scale，GAF）评定，分析PSP在抑郁症患者中的内部一致性、与GAF的一致性以及与MADRS的相关性。另外，6例抑郁症病例在首次评定后的1周进行再次评定用以PSP重测一致性的检验。结果PSP的内部一致性Cron—bachd系数为0．760，PSP总分与GAF评分具有良好的正相关（r=0．906，P〈0．01），与MADRs总分呈负相关，具有统计学意义（r=-0．652，P〈0．01），重测一致性的kappa值为0．945（n=6，P=0．01）。结论PSP是一个操作简单、稳定性高的评估工具，可用于抑郁症患者社会功能的评估。量表中d维度（冲动和攻击行为）对整个量表的权重大，在抑郁症患者中与总分相关性欠佳。
基金We thank L.L.Looger(Janelia Farm Research Campus)for providing the mEos2 cDNA and Toshio Yanagida(Osaka University,Japan)for sharing the Q rods.This work was supported by grants from the National Basic Research Program(973 Program)(Nos.2010CB833701 and 2010CB912303)the National Key Technology R&D Program(SQ2011SF11B01041)+2 种基金the National Natural Science Foundation of China(Grant Nos.31130065,31170818,90913022,31127901,and 31100615)the Beijing Natural Science Foundation(7121008)the Chinese Academy of Sciences Project(KSCX1-1W-J-3,KSCX2-EWQ-11,and 2009-154-27).
文摘The resolution of single molecule localization imaging techniques largely depends on the precision of localization algorithms.However,the commonly used Gaussian function is not appropriate for anisotropic dipoles because it is not the true point spread function.We derived the theoretical point spread function of tilted dipoles with restricted mobility and developed an algorithm based on an artifi cial neural network for estimating the localization,orientation and mobility of individual dipoles.Compared with fi tting-based methods,our algorithm demonstrated ultrafast speed and higher accuracy,reduced sensitivity to defocusing,strong robustness and adaptability,making it an optimal choice for both two-dimensional and threedimensional super-resolution imaging analysis.
