66例输液反应分析及对策

目的:通过分析临床发生输液反应的原因,寻找预防措施,减少输液反应发生率。方法:对本院2005年1月—2009年6月66例输液反应资料进行回顾性分析。结果:输液反应的发生与药品种类、合并使用,患者年龄、体质,输液操作、滴注速度等多因素相关。结论:严格执行"四查十对",掌握药品配伍禁忌,加强无菌操作是控制输液反应发生的关键。

Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury

Liver ischemia-reperfusion injury(IRI) is an inherent feature of liver surgery and liver transplantation in which damage to a hypoxic organ(ischemia) is exacerbated following the return of oxygen delivery(reperfusion). IRI is a major cause of primary nonfunction after transplantation and may lead to graft rejection, regardless of immunological considerations. The immediate response involves the disruption of cellular mitochondrial oxidative phosphorylation and the accumulation of metabolic intermediates during the ischemic period, and oxidative stress during blood flow restoration. Moreover, a complex cascade of inflammatory mediators is generated during reperfusion, contributing to the extension of the damage and finally to organ failure. A variety of pharmacological interventions(antioxidants, anticytokines, etc.) have been proposed to alleviate graft injury but their usefulness is limited by the local and specific action of the drugs and by their potential undesirable toxic effects. Polyethylene glycols(PEGs), which are non-toxic water-soluble compounds approved by the FDA, have been widely used as a vehicle or a base in food, cosmetics and pharmaceuticals, and also as adjuvants for ameliorating drug pharmacokinetics. Some PEGs are also currently used as additives in organ preservation solutions prior to transplantation in order to limit the damage associated with cold ischemia reperfusion. More recently, the administration of PEGs of different molecular weights by intravenous injection has emerged as a new therapeutic tool to protect liver grafts from IRI. In this review, we summarize the current knowledge concerning the use of PEGs as a useful target for limiting liver IRI.

Effect of Transition Metals (Cu, Co and Fe) on the Autothermal Reforming of Methane over Ni/Ce_(0.2)Zr_(0.1)Al_(0.7)O_δ Catalyst

The transition metals （Cu, Co, and Fe） were applied to modify Ni/Ce0.2Zr0.1Al0.7Oδ catalyst. The effects of transition metals on the catalytic properties of Ni/Ce0.2Zr0.1Al0.7Oδ autothermal reforming of methane were investigated. The Ni-supported catalysts were characterized by XRD, TPR and XPS. Tests in autothermal reforming of methane to hydrogen showed that the addition of transition metals （Cu and Co） significantly increased the activity of catalyst under the conditions of lower reaction temperature, and Ni/Cu0.05Ce0.2Zr0.1Al0.65Oδ was found to have the highest conversion of CH4 among all catalysts in the operation temperatures ranging from 923 K to 1023 K. TPR, XRD and XPS measurements indicated that the cubic phases of CexZr1-xO2 solid solution were formed in the preparation process of catalysts. Strong interaction was found to exist between NiO and CexZr1-xO2 solid solution. The addition of Cu improved the dispersion of NiO, inhibited the formation of NiAl2O4, and thus significantly promoted the activity of the catalyst Ni/Cu0.05Ce0.2Zr0.1Al0.65Oδ

EXACT BOUNDARY CONTROLLABILITY FOR HIGHER ORDER QUASILINEAR HYPERBOLIC EQUATIONS

By means of the existence and uniqueness of semi-global C1 solution to the mixed initial-boundary value problem with general nonlinear boundary conditions for first order quasilinear hyperbolic systems with zero eigenvalues,the local exact boundary controllability for higher order quasilinear hyperbolic equations is established.

Analytical Modeling of Threshold Voltage for Double-Gate MOSFET Fully Comprising Quantum Mechanical Effects

The analytical solutions to 1D Schrdinger equation (in depth direction) in double gate (DG) MOSFETs are derived to calculate electron density and threshold voltage.The non uniform potential in the channel is concerned with an arbitrary depth so that the analytical solutions agree well with numerical ones.Then,an implicit expression for electron density and a closed form of threshold voltage are presented fully comprising quantum mechanical (QM) effects.This model predicts an increased electron density with an increasing channel depth in subthreshold region or mild inversion region.However,it becomes independent on channel depth in strong inversion region,which is in accordance with numerical analysis.It is also concluded that the QM model,which barely considers a box like potential in the channel,slightly over predicts threshold voltage and underestimates electron density,and the error increases with an increasing channel depth or a decreasing gate oxide thickness.

Thermal Stability and Reductive Property of Ce_xZr_(1-x)O_2 Solid Solution Doped Simultaneously by Fe, Mn or Fe, Cu

CexZr1-xO2 complex oxides doped by transition metal(Fe, Mn, Cu) were prepared by precipitation method. Thermal stability of samples was characterized by XRD, surface areas were measured by BET method and reductive property was characterized by TPR. The results show that MnO2 can be dispersed in solid solution after calcined at 1273 K, when the loading is 12%, while Fe and Cu is easy to separate from samples at this temperature. Samples doped simultaneously by Fe, Mn or Fe, Cu demonstrated high reactive property at low temperature. The starting reduction temperature are 413 and 373 K, respectively. TPR results also show a broad range of reductive temperature exists in these bi-metal doped samples.

Solute carrier family 2 members 1 and 2 as prognostic biomarkers in hepatocellular carcinoma associated with immune infiltration

BACKGROUND Metabolic reprogramming has been identified as a core hallmark of cancer.Solute carrier family 2 is a major glucose carrier family.It consists of 14 members,and we mainly study solute carrier family 2 member 1(SLC2A1)and solute carrier family 2 member 2(SLC2A2)here.SLC2A1,mainly existing in human erythrocytes,brain endothelial cells,and normal placenta,was found to be increased in hepatocellular carcinoma(HCC),while SLC2A2,the major transporter of the normal liver,was decreased in HCC.AIM To identify if SLC2A1 and SLC2A2 were associated with immune infiltration in addition to participating in the metabolic reprogramming in HCC.METHODS The expression levels of SLC2A1 and SLC2A2 were tested in HepG2 cells,HepG215 cells,and multiple databases.The clinical characteristics and survival data of SLC2A1 and SLC2A2 were examined by multiple databases.The correlation between SLC2A1 and SLC2A2 was analyzed by multiple databases.The functions and pathways in which SLC2A1,SLC2A2,and frequently altered neighbor genes were involved were discussed in String.Immune infiltration levels and immune marker genes associated with SLC2A1 and SLC2A2 were discussed from multiple databases.RESULTS The expression level of SLC2A1 was up-regulated,but the expression level of SLC2A2 was down-regulated in HepG2 cells,HepG215 cells,and liver cancer patients.The expression levels of SLC2A1 and SLC2A2 were related to tumor volume,grade,and stage in HCC.Interestingly,the expression levels of SLC2A1 and SLC2A2 were negatively correlated.Further,high SLC2A1 expression and low SLC2A2 expression were linked to poor overall survival and relapse-free survival.SLC2A1,SLC2A2,and frequently altered neighbor genes played a major role in the occurrence and development of tumors.Notably,SLC2A1 was positively correlated with tumor immune infiltration,while SLC2A2 was negatively correlated with tumor immune infiltration.Particularly,SLC2A2 methylation was positively correlated with lymphocytes.CONCLUSION SLC2A1 and SLC2A2 are independent therapeutic targets for HCC,and they are quintessential marker molecules for predicting and regulating the number and status of immune cells in HCC.

ANALYTICAL SOLUTION OF FILLING AND EXHAUSTING PROCESS IN PNEUMATIC SYSTEM

The filling and exhausting processes in a pneumatic system are involved with many factors, and numerical solutions of many partial differential equations are always adapted in the study of those processes, which have been proved to be troublesome and less intuitive. Analytical solutions based on loss-less tube model and average friction tube model are found respectively by using fluid net theory, and they fit the experimental results well. The research work shows that： Fluid net theory can be used to solve the analytical solution of filling and exhausting processes of pneumatic system, and the result of loss-less tube model is close to that of average friction model, so loss-less tube model is recommended since it is simpler, and the difference between filling time and exhausting time is determined by initial and final pressures, the volume of container and the section area of tube, and has nothing to do with the length of the tube.

New Generalized Transformation Method and Its Application in Higher-Dimensional Soliton Equation

A new generalized transformation method is differential equation. As an application of the method, we presented to find more exact solutions of nonlinear partial choose the （3＋1）-dimensional breaking soliton equation to illustrate the method. As a result many types of explicit and exact traveling wave solutions, which contain solitary wave solutions, trigonometric function solutions, Jacobian elliptic function solutions, and rational solutions, are obtained. The new method can be extended to other nonlinear partial differential equations in mathematical physics.

Preparation and Characterization of Ce_x Th_(1-x)O_2 Solid Solutions Prepared by Sol-Gel Method

The Ce_xTh_(1-x)O_2 solid solutions were prepared by citrate sol-gel method,and their structure and reduction properties were studied. XRD shows that solid solution with cubicphase formed in all the solid solutions (x = 0.2, 0.5, 0.8) Ce_xTh_(1-x)O_2. Raman spectrum showsthat Ce-Th complex oxides can promote the formation of oxygen vacancies. Two reduction peaks appearin the TPR profiles of Ce_xTh_(1-x)O_2 solid solution. The a peak is attributed to the reduction ofCe^(4+) on the surface, and the β peak is attributed to the reduction of bulk CeO_2. Theincorporation of Th atom into CeO_2 improves the reduction of CeO_2. Ce_xTh_(1-x)O_2 mixed oxidesare promising materials for oxygen vacancies produced, as well as catalysts for many reactionsinvolved oxygen, such as the catalysts for three-way reactions for reducing the releasing pollutantsor combustion of VOCs.

EXACT SOLUTIONS OF THE VARIABLE COEFFICIENT KdV AND SG TYPE EQUATIONS

In this paper,the variable cofficient KdV equation with dissipative loss and nonuniformity terms and the variable coefficient SG equation with nonuniformity term are studied. The exact solutions of the KdV and SG equations are obtained.In particular,the soliton solutions of two equations are found. Received November 25,1996.Revised June 30,1997.1991 MR Subject Classification:35Q53.

{P,Q,k+1}-reflexive solutions to a system of matrix equations

In this paper,we investigate the{P,Q,k+1}-reflexive and anti-reflexive solutions to the system of matrix equations AX=C,XB=D and AXB=E.We present the necessary and sufficient conditions for the system men-tioned above to have the{P,Q,k+1}-reflexive and anti-reflexive solutions.We also obtain the expressions of such solutions to the system by the singular value decomposition.Moreover,we consider the least squares{P,Q,k+1}-reflexive and anti-reflexive solutions to the system.Finally,we give an algorithm to illustrate the results of this paper.

2N + 1-soliton Solutions of Boussinesq-Burgers Equation

2N + 1-soliton solutions of Boussinesq-Burgers equation are obtained by using the Hirota bilinear derivative method and the perturbation technique.Further,we give the graphs of corresponding three-and five-soliton solutions.

The (G'/G, 1/G)-expansion method and its application to travelling wave solutions of the Zakharov equations

The （G＇/G, 1/G）-expansion method for finding exact travelling wave solutions of nonlinear evolution equations, which can be thought of as an extension of the （G＇/G）-expansion method proposed recently, is presented. By using this method abundant travelling wave so- lutions with arbitrary parameters of the Zakharov equations are successfully obtained. When the parameters are replaced by special values, the well-known solitary wave solutions of the equations are rediscovered from the travelling waves.

Solving (2+1)-dimensional sine-Poisson equation by a modified variable separated ordinary differential equation method

By introducing a more general auxiliary ordinary differential equation （ODE）, a modified variable separated ordinary differential equation method is presented for solving the （2 ＋ 1）-dimensional sine-Poisson equation. As a result, many explicit and exact solutions of the （2 ＋ 1）-dimensional sine-Poisson equation are derived in a simple manner by this technique.

1/3 SUBHARMONIC SOLUTION OF ELLIPTICAL SANDWICH PLATES

The problem of nonlinear forced oscillations for elliptical sandwich plates is dealt with. Based on the governing equations expressed in terms of five displacement components, the nonlinear dynamic equation of an elliptical sandwich plate under a harmonic force is derived. A superpositive-iterative harmonic balance (SIHB) method is presented for the steady-state analysis of strongly nonlinear oscillators. In a periodic oscillation, the periodic solutions can be expressed in the form of basic harmonics and bifurcate harmonics. Thus, an oscillation system which is described as a second order ordinary differential equation, can be expressed as fundamental differential equation with fundamental harmonics and incremental differential equation with derived harmonics. The 1/3 subharmonic solution of an elliptical sandwich plate is investigated by using the methods of SIHB. The SIHB method is compared with the numerical integration method. Finally, asymptotical stability of the 1/3 subharmonic oscillations is inspected.

Current Carriers Scattering in InP-InAs Solid Solutions

Electrical parameters of n-type InPxAs1-x solid solution crystals have been investigated in the range of 4.2-300 K. Theoretical calculations of current carriers mobility have been carried out and they are in good agreement with experimental results. The contribution of current carriers scattering main mechanisms has been determined. Comparison of experimental and theoretical data has shown minor contribution of disorder scattering associated with the disordered arrangement of atoms in InPxAs1-x solid solutions. Contribution of the disorder scattering increases with increasing of InP composition in solid solutions system at fixed temperatures and weakens with lowering of temperature and never dominates. A maximal share of the ＂alloy＂ scattering observed in experimental samples of lnPxAs1-x solid solutions differs from the similar scattering in SiGe alloys. It does not exceed - 20% of total scattering at 300 K and - 10% at lower temperature. A relative small contribution of disorder scattering is important for the devices designed on the base of InPxAs1-x system.

Effect of Heat Treatment Conditions on Photo sensitivity of CdSexS1-x Polycrystalline Films

The influence of thermal treatment on the lux-ampere characteristics of polycrystalline films from the CdSexS1-x solid solution obtained by the method of thermal evaporation in a vacuum has been investigated. It is shown that at low illumination intensities L μ of electrons increases with a power law μ ~ Lγ, first with the exponent γ > 1, then with γ ≈ 0.5, and their concentration n almost does not change. Starting from the intensity L > 12 - 15 lx, the electron concentration increases strongly n ~ Lβ from β ≈ 3.0, and the parameters n and μ reach relatively high values ~(1015 - 1016) sm-3 and ~(150 - 200) sm2/V·s, however further, at L > 50 lx, a weak dependence of n(L) and μ(L) with β, γ < 1.0 is found. The obtained experimental results are interpreted on the basis of a model of a semiconductor film with intergranular potential barriers when the concentration and barrier mechanisms of photoconductivity operate simultaneously.

ZTE's Solution to Convergence of WLAN and CDMA2000 1x

Based on the analysis on features of WLAN and CDMA2000 1x.the paper details ZTE's solution to the convergence.of WLAN and CD- MA2000 1x from the perspectives of network architecture and sys- tem components,and analyzes the advantages of the scheme,and presents application by Shanghai Unicom.