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Global research status and trends of somatic symptom disorder: A bibliometric study
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作者 Chao Yang Kun Zhang +3 位作者 Qian Wang Shuai Wang Huan Li Kai Zhang 《World Journal of Psychiatry》 SCIE 2025年第1期168-178,共11页
BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is lacking.AIM To conduct a bibliometric analysis to investigate the current status and fronti... BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is lacking.AIM To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.METHODS The documents related to SSD are obtained from the web of science core collection database(WoSCC),and VOSviewer 1.6.16 from January 1,2000 to December 31,2023,and the WoSCC’s literature analysis wire were used to conduct the biblio-metric analysis.RESULTS A total of 567 documents related to SSD were included,and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research,published in 277 journals.The most productive author,institution,country and journal were Löwe B,University of Hamburg,Germany,and Journal of Psycho-somatic Research respectively.The first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues,which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.CONCLUSION In conclusion,the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria,functional impairment of SSD,and the treatment for SSD.More high-quality studies are needed to assess the diagnosis and treatment of SSD. 展开更多
关键词 somatic symptom disorder Validity and reliability Functional impairment Treatment Bibliometric analysis
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Impact of Somatic Symptoms on Identification of Depression among General Outpatients by Family Physicians in North-Western Nigeria
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作者 Auwal Sani Salihu 《Open Journal of Psychiatry》 2015年第3期278-284,共7页
In many places in the world, General Practitioners are only able to identify depression in a small fraction of depressed patients presenting to general outpatient department. The effect of somatic symptoms on its reco... In many places in the world, General Practitioners are only able to identify depression in a small fraction of depressed patients presenting to general outpatient department. The effect of somatic symptoms on its recognition was investigated. The study determines the identification rate of depression by general practitioners among outpatients with somatic symptoms and those without somatic symptoms. This descriptive cross sectional study was conducted in Family Medicine Department, Aminu Kano Teaching Hospital, Kano, Nigeria. The Hospital Anxiety and Depression Scale (HADS) was used to screen selected participants. Forms were used by GPs to itemize medical and psychiatric symptoms elicited as well as medical and psychiatric diagnoses made. Schedule for Clinical Assessment in Neuropsychiatry (SCAN) version 2.1, was used to confirm the diagnosis of depression. Hamilton Depression Rating Scale (HDRS) was used for severity using items 11-14 of Hamilton Depression Rating Scale. Those with somatic symptoms score of 1-3 were rated as having low and those with 4-10 were rated as having high. Of the 410 outpatients recruited, 402 participated in the study. Two hundred and thirteen were screened depressed (HADS). Two hundred were confirmed depressed using SCAN (49.8%). The GPs identified 31.3% of those participants diagnosed depressed without somatic symptoms compared to 15.2% of those who were diagnosed depressed with somatic symptoms. However, no significant association was found between GPs ability to identify depression in the presence or absence of somatic symptoms (p = 0.09). This study found no association between GPs ability to identify depression and presence or absence of somatic symptoms (χ2 = 2.75, p = 0.09). However, this study found that the higher the level of somatic symptoms the more unlikely it’s for GPs to identify depression. To reduce the burden of depression by early detection and treatment, continuing medical education of GPs should include skills in identification of depression. 展开更多
关键词 DEPRESSION GENERAL OUTPATIENTS GENERAL Practitioners NIGERIA IDENTIFICATION somatic symptoms
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Somatization Symptoms in a Primary Care Clinic at a Tertiary Hospital in Southern Nigeria
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作者 Chidi J. Okafor Bassey Edet Udeme Asibong 《Journal of Biosciences and Medicines》 2015年第10期67-73,共7页
Background: Somatic symptoms that are not attributable to organic pathology are common in general practice settings however, data in most parts of Africa including southern Nigeria are still scarce. The aim of our stu... Background: Somatic symptoms that are not attributable to organic pathology are common in general practice settings however, data in most parts of Africa including southern Nigeria are still scarce. The aim of our study was to examine such somatic symptoms reported by patients attending a primary care facility at a tertiary hospital in southern Nigeria as well as to motivate future research in this area. Method: The study was conducted at the General Out Patient Clinic (GOPC) of the University of Calabar Teaching Hospital (UCTH). It was a cross sectional study in which data were obtained from the case notes of 115 patients that presented in the clinic with somatic complaints which could not be attributed to organic pathology by their physicians. Results: While 46 of the patients were males, 69 were females. Their mean age was 37.7 (SD = 11.9). Internal heat, crawling sensation, body pains and palpitations were the most prevalent symptoms reported by the patients. When the symptoms were sorted into various groups, the “subjective abnormal bodily sensation” was the most prevalent and far outnumbered the “pseudo neurological symptoms”. Conclusion: A number of patients attending the GOPC of the UCTH seek consultations for medically unexplained somatic symptom. The most prevalent of these symptoms are internal heat and crawling sensations both of which are not stated in the criteria recognized by the International Classification of Diseases—version 10 (ICD-10) for the diagnosis of psychiatric disorders. 展开更多
关键词 somatIZATION Medically UNEXPLAINED somatic symptom Abnormal Bodily SENSATIONS SOUTHERN NIGERIA
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Simulating the mind and applications-a theory-based chance for understanding psychic transformations in somatic symptom disorders
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作者 Henriette Löffler-Stastka Dietmar Dietrich +2 位作者 Thilo Sauter Martin Fittner Dagmar Steinmair 《World Journal of Meta-Analysis》 2021年第6期474-487,共14页
With the new category of somatic symptom disorder/bodily distress disorder in ICD-11,research into pathogenetic and therapeutic pathways is stimulated.By turning away from the definition of somatoform disorders as“th... With the new category of somatic symptom disorder/bodily distress disorder in ICD-11,research into pathogenetic and therapeutic pathways is stimulated.By turning away from the definition of somatoform disorders as“the lack of something physical explaining everything”,this new classification might offer a way to put the focus on the individual patient’s psychodynamic balance and conflicts and their condensation in the symptom.Modelling and simulation have a long history in science to gain insight also into complex phenomena.Considering the evolution of precision medicine many different parameters are meanwhile operationalised and ready for consequent process research.Calculation models have to fit to the complexity of this disorder category.In an interdisciplinary discourse between computer and medical/psychoanalytic scientists a multilayer,fine grained calculation model is elaborated.Starting from a clinical case history,within iterative discussion,by acknowledging the demand for interdisciplinary synergy and cooperation in science,psychoanalytic theory served as the basis for computer-scientific information technique.A parallelisation with the Mealy model helped to establish a meaningful calculation possibility for further process research.How psychic transformations can be understood properly in order to provide meaningful treatments,the respective training,and to conduct appropriate process-and outcome-research is established in simulating the mind and applications. 展开更多
关键词 Psychic transformation Computer-technology Simulation somatic symptom disorder Bodily distress disorder Mealy model
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Subjective symptoms related to depression and suicidal risk in a Japanese community: a cross-sectional study
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作者 Shigeki Takemura Kouichi Yoshimasu +2 位作者 Jin Fukumoto Hiroichi Yamamoto Kazuhisa Miyashita 《Open Journal of Psychiatry》 2011年第2期40-48,共9页
BACKGROUND: This cross-sectional study aimed to assess the association between self-reported somatic and mental symptoms and the presence of major depressive disorder (MDD) and suicidal risk among community dwellers i... BACKGROUND: This cross-sectional study aimed to assess the association between self-reported somatic and mental symptoms and the presence of major depressive disorder (MDD) and suicidal risk among community dwellers in Japan. METHODS: From two locations in Japan, we recruited 734 community dwellers who underwent an annual health screening. Basic symptoms of MDD, dysthymia, and the presence of associated suicidal risk were determined using a brief structured diagnostic psychiatric interview, Mini International Neuropsychiatric Interview (MINI). Information regarding self-reported somatic and mental symptoms was obtained from a self-administered questionnaire used in the annual health check-up. Suicidal risk was evaluated on the basis of six relevant questions asked in MINI. Logistic regression model was used to calculate age- and gender-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for MDD. Further adjustment for basic symptoms of MDD was performed to calculate ORs and CIs for suicidal risk. RESULTS: A myriad of somatic symptoms, including headache, heavy headedness, eye strain, and shoulder stiffness [adjusted OR (95% CI), 11.4 (1.22 - 107) at location 1;5.17 (1.23 - 21.7) at location 2], were associated with the presence of MDD. Dysmenorrhea [6.07 (1.14 - 32.3) at location 1] and dysesthesia, arthralgia, and swelling in the extremities [2.72 (1.14 - 6.47) at location 2] were significantly associated with an increase in suicidal risk, independent of the presence of basic symptoms of MDD. CONCLUSION: Several somatic symptoms, especially pain-related ones, may serve as possible signs of depression and suicidal risk among community dwellers. 展开更多
关键词 EPIDEMIOLOGY somatic symptoms DEPRESSION SUICIDE COMMUNITY Dwellers
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The need for long-term surveillance of recovery of psychiatric patients with somatic complaints
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作者 Marja Kokkonen Kari Salke +2 位作者 Tarja Saharinen Kaisa Haatainen Heli Koivumaa-Honkanen 《Open Journal of Psychiatry》 2012年第2期157-163,共7页
Objective: Treatment of psychiatric patients with psychosomatic or somatic symptoms needs special attention. Methods: We examined correlates, change and recovery from depression among psychiatric patients (n = 150) du... Objective: Treatment of psychiatric patients with psychosomatic or somatic symptoms needs special attention. Methods: We examined correlates, change and recovery from depression among psychiatric patients (n = 150) during the assessment of their work ability. Patients were referred to an open psychiatric ward during 8/2004-9/2005. Psychiatric diseases were diagnosed with the ICD-10 by the psychiatrist, but also the Structured Clinical Interview for DSM-IV (SCID I and II) was conducted. The patients replied to questionnaires after admission and before discharge including questions on life changes, somatic health, psychosocial and health-related factors as well as psychometric scales for depression (BDI), life satisfaction (LS) and general psychopathology (SCL). RESULTS. At baseline, 75% of the patients reported clinically significant depression (BDI > 15) and a quarter of them experienced their depression as severe (BDI ≥ 30). Whereas, according to ICD-10 guidelines, 91% of the patients suffered from depressive disorder and 66% of them from major depression. The average duration of inpatient evaluation was 24 (SD 9, 4) days. Baseline poor general health, life dissatisfaction, psychosomatic symptoms, bodily pains as well as poor financial situation and adverse life events predicted prevailing depression at discharge. Clinical symptoms improved significantly, especially among younger patients, recovery could not be reached by the time of discharge. Conclusions: Psychiatric patients with somatic complaints tended to under-rate their depression. To enhance their recovery, long-term and individually planned out-patient treatment and surveillance are needed. 展开更多
关键词 DEPRESSION BDI somatic symptoms LIFE SATISFACTION LIFE Events
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Irritable bowel syndrome: Relations with functional, mental, and somatoform disorders 被引量:13
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作者 Constanze Hausteiner-Wiehle Peter Henningsen 《World Journal of Gastroenterology》 SCIE CAS 2014年第20期6024-6030,共7页
This review describes the conceptual and clinical relations between irritable bowel syndrome (IBS), other functional, somatoform, and mental disorders, and points to appropriate future conceptualizations. IBS is consi... This review describes the conceptual and clinical relations between irritable bowel syndrome (IBS), other functional, somatoform, and mental disorders, and points to appropriate future conceptualizations. IBS is considered to be a functional somatic syndrome (FSS) with a considerable symptom overlap with other FSSs like chronic fatigue syndrome or fibromyalgia syndrome. IBS patients show an increased prevalence of psychiatric symptoms and disorders, especially depression and anxiety. IBS is largely congruent with the concepts of somatoform and somatic symptom disorders. Roughly 50% of IBS patients complain of gastrointestinal symptoms only and have no psychiatric comorbidity. IBS concepts, treatment approaches, as well as health care structures should acknowledge its variability and multidimensionality by: (1) awareness of additional extraintestinal and psychobehavioral symptoms in patients with IBS; (2) general and collaborative care rather than specialist and separated care; and (3) implementation of &#x0201c;interface disorders&#x0201d; to abandon the dualistic classification of purely organic or purely mental disorders. 展开更多
关键词 Functional somatic syndrome somatoform disorder somatic symptom disorder Bodily distress syndrome Interface Irritable bowel syndrome
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Efficacy Evaluation for Depression with Somatic Symptoms Treated by Electroacupuncture Combined with Fluoxetine 被引量:4
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作者 段冬梅 图娅 +1 位作者 陈利平 吴整军 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2009年第3期167-173,共7页
Objective: This study is to investigate the clinical therapeutic effects and safety of treating mild or moderate depression with somatic symptoms with electroacupuncture combined with Fluoxetine. Methods: 95 cases of ... Objective: This study is to investigate the clinical therapeutic effects and safety of treating mild or moderate depression with somatic symptoms with electroacupuncture combined with Fluoxetine. Methods: 95 cases of mild or moderate depression with somatic symptoms were randomly divided into a Fluoxetine group, and an electroacupuncture plus Fluoxetine group. Hamilton Depression Scale (HAMD) was used for the assessment of clinical therapeutic effects and Treatment Emergent Symptom Scale (TESS) was used for assessment of adverse reactions. Results: The total effective rate was 77.27% in the Fluoxetine group and 78.26% in the electroacupuncture plus Fluoxetine group, showing no statistically significant difference between these two groups (P>0.05). However, the treatment took effect after two weeks in the electroacupuncture plus Fluoxetine group but after four weeks in Fluoxetine group. During this time, a better therapeutic effect on depression with mild or moderate somatic symptoms was found in the electroacupuncture plus Fluoxetine group, which also had fewer adverse reactions than the Fluoxetine group. Conclusion: Electroacupuncture combined with Fluoxetine takes effect faster for relieving the somatic symptoms with fewer adverse reactions. It is worth popularizing clinically. 展开更多
关键词 ELECTROACUPUNCTURE somatic symptoms FLUOXETINE DEPRESSION
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Do patients with gastroesophageal reflux disease and somatoform tendencies benefit from antireflux surgery? 被引量:2
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作者 Hans Friedrich Fuchs Benjamin Babic +3 位作者 Karl-Hermann Fuchs Wolfram Breithaupt Gabor Varga Frauke Musial 《World Journal of Gastroenterology》 SCIE CAS 2019年第3期388-397,共10页
BACKGROUND The clinical presentation of gastroesophageal reflux disease(GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in th... BACKGROUND The clinical presentation of gastroesophageal reflux disease(GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in the symptomatic spectrum between proven GERD and other disorders such as dyspepsia, functional heartburn and/or somatoform disorders.AIM To prospectively evaluate the GERD patients with and without somatoform disorders before and after laparoscopic antireflux surgery.METHODS In a tertiary referral center for foregut surgery over a period of 3 years patients with GERD, qualifying for the indication of laparoscopic antireflux surgery, were investigated prospectively regarding their symptomatic spectrum in order to identify GERD and associated somatoform disorders. Assessment of symptoms was performed by an instrument for the evaluation of somatoform disorders[Somatoform Symptom Index(SSI) > 17]. Quality of life was evaluated by Gastrointestinal Quality of Life Index(GIQLI).RESULTS In 123 patients an indication for laparoscopic antireflux surgery was established and in 43 patients further medical therapy was suggested. The portion of somatoform tendencies in the total patient population was 20.48%(34 patients).Patients with a positive SSI had a preoperative GIQLI of 77(32-111). Patients with a normal SSI had a GIQLI of 105(29-140)(P < 0.0001). In patients with GERD the quality of life could be normalized from preoperative reduced values of GIQLI102(47-140) to postoperative values of 117(44-144). In patients with GERD and somatoform disorders, the GIQLI was improved from preoperative GIQLI 75(47-111) to postoperative 95(44-122)(P < 0.0043).CONCLUSION Patients with GERD and associated somatoform disorders have significantly worse levels of quality of life. The latter patients can also benefit from laparoscopic fundoplication, however they will not reach a normal level. 展开更多
关键词 GASTROESOPHAGEAL REFLUX DISEASE ANTIREFLUX surgery Laparoscopic fundoplication somatIZATION GASTROESOPHAGEAL REFLUX DISEASE symptoms
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经颅微电流刺激联合本森放松技术在首发抑郁症患者中的临床应用 被引量:1
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作者 吕有良 朱俊芳 +2 位作者 王芳 蔡莹莹 郝以辉 《海南医学》 CAS 2024年第8期1096-1101,共6页
目的探讨经颅微电流刺激(CES)联合本森放松技术(BRT)对首发抑郁症患者神经递质、抑郁及躯体化症状的调控作用。方法选取2022年6月至2023年3月郑州大学第一附属医院精神医学科收治的108例首发抑郁症患者纳入研究,按随机数表法分为观察组... 目的探讨经颅微电流刺激(CES)联合本森放松技术(BRT)对首发抑郁症患者神经递质、抑郁及躯体化症状的调控作用。方法选取2022年6月至2023年3月郑州大学第一附属医院精神医学科收治的108例首发抑郁症患者纳入研究,按随机数表法分为观察组、对照1组和对照2组,每组36例。所有患者均采取常规药物治疗,于此基础上对照1组采取CES治疗,对照2组采取BRT治疗,观察组患者采取CES联合BRT治疗,连续治疗8周。比较三组患者治疗前、治疗4周、8周后的神经递质[5-羟色胺(5-HT)、多巴胺(DA)、去甲肾上腺素(NE)]水平、重复性成套神经心理状态测试(RBANS)、汉密尔顿抑郁量表(HAMD)、自杀意念量表(BSI-CV)及躯体症状群量表(PHQ-15)评分。结果治疗前,三组患者的神经递质水平比较差异均无统计学意义(P>0.05);治疗4周、8周后,三组患者的神经递质水平呈逐渐升高趋势,且治疗4周、8周后,观察组患者的血清5-HT、DA、NE水平>对照1组>对照2组,差异均有统计学意义(P<0.05)。治疗前和治疗4周后,三组患者的认知功能水平比较差异均无统计学意义(P>0.05);治疗4周、8周后,三组患者的认知功能评分呈逐渐升高趋势,且治疗8周后,观察组患者的认知功能评分>对照1组>对照2组,差异均有统计学意义(P<0.05)。治疗前,三组患者的HAMD、BSI-CV评分比较差异均无统计学意义(P>0.05);治疗4周、8周后,三组患者的HAMD、BSI-CV评分呈逐渐降低趋势,且治疗4周、8周后,观察组患者的HAMD、BSI-CV评分<对照2组<对照1组,差异均有统计学意义(P<0.05)。治疗前,三组患者的PHQ-15评分比较差异均无统计学意义(P>0.05);治疗4周、8周后,三组患者的PHQ-15评分呈逐渐降低趋势,且治疗4周、8周后,观察组患者的PHQ-15评分低于对照1组和对照2组,差异均有统计学意义(P<0.05),但对照1组和对照2组间比较差异均无统计学意义(P>0.05)。结论CES联合BRT应用于首发抑郁症患者可发挥协同作用,有助于改善患者神经递质水平,减轻抑郁及躯体化症状,降低自杀意念。 展开更多
关键词 抑郁症 经颅微电流刺激 本森放松技术 神经递质 躯体化症状 认知功能
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文拉法辛联合氟西汀对伴焦虑症状重度抑郁症患者的效果 被引量:3
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作者 林荫 赖珏 +1 位作者 林春燕 李佳 《西北药学杂志》 CAS 2024年第2期200-205,共6页
目的探讨文拉法辛联合氟西汀对伴焦虑症状重度抑郁症(major depressive disorder,MDD)患者躯体症状、睡眠质量及血清5-羟色胺(5-hydroxytryptamine,5-HT)、皮质醇(cortisol,Cor)和脑源性神经营养因子(brain-derived neurotrophic factor... 目的探讨文拉法辛联合氟西汀对伴焦虑症状重度抑郁症(major depressive disorder,MDD)患者躯体症状、睡眠质量及血清5-羟色胺(5-hydroxytryptamine,5-HT)、皮质醇(cortisol,Cor)和脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)水平的影响。方法将收治的149例MDD伴焦虑症状患者用数字表法随机分为对照组(74例)和研究组(75例)。对照组给予氟西汀治疗,研究组在对照组治疗的基础上给予文拉法辛治疗。比较2组治疗8周后的临床疗效、焦虑、抑郁、躯体症状、睡眠质量和血清5-HT、Cor和BDNF水平以及安全性。结果治疗8周后,研究组的治疗有效率(97.33%)显著高于对照组(87.84%),P<0.05;研究组汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分均显著低于对照组(P<0.01);研究组躯体症状群量表(questionnaire-15,PHQ-15)、临床总体印象量表(clinical global impression-severity of illness,CGI-S)和匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评分均显著低于对照组(P<0.01);研究组5-HT、去甲肾上腺素(norepinephrine,NE)均显著高于对照组(P<0.01);研究组Cor显著低于对照组,BDNF显著高于对照组(P<0.01);2组各类不良反应发生率比较差异无统计学意义。结论文拉法辛联合氟西汀治疗伴焦虑症状MDD患者疗效显著,能有效改善患者的焦虑、抑郁症状,躯体症状和睡眠质量;提高血清5-HT和BDNF水平,调节神经递质;抑制Cor的过多分泌,实现对神经细胞功能的有效改善。 展开更多
关键词 文拉法辛 氟西汀 重度抑郁症 躯体症状 睡眠质量 5-羟色胺 皮质醇 脑源性神经营养因子
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慢性偏头痛病人躯体化症状与焦虑、抑郁的横断面分析 被引量:3
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作者 傅增辉 金艳 +6 位作者 林再红 姜岩 杜姝 刘晶 张广萍 刘旸 于绘丽 《中国疼痛医学杂志》 CSCD 北大核心 2024年第1期38-45,共8页
目的:探讨慢性偏头痛(chronic migraine, CM)病人躯体化症状与焦虑、抑郁状况,为慢性偏头痛病人精神心理评估与干预提供借鉴。方法:收集2022年1月至2023年2月齐齐哈尔医学院附属第三医院就诊的278例CM病人。收集病人一般临床资料,采用... 目的:探讨慢性偏头痛(chronic migraine, CM)病人躯体化症状与焦虑、抑郁状况,为慢性偏头痛病人精神心理评估与干预提供借鉴。方法:收集2022年1月至2023年2月齐齐哈尔医学院附属第三医院就诊的278例CM病人。收集病人一般临床资料,采用躯体化症状自评量表(self-rating somatic symptom scale, SSS)、广泛性焦虑障碍量表-7 (generalized anxiety disorder-7, GAD-7)、病人健康问卷-9(9 patient health questionnaire, PHQ-9)、匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index, PSQI)、数字分级评分法(numerical rating scale, NRS)评分和偏头痛失能程度量表(migraine disability assessment,MIDAS)分别对躯体化症状、焦虑、抑郁、睡眠、头痛程度和失能程度进行评价。结果:150名CM病人SSS量表筛查呈阳性,阳性率为53.96%。与128例SSS阴性CM病人相比,SSS阳性CM病人教育年限、头痛程度评分、头痛持续时间、发作频率、头痛病程、失能程度评分、抑郁评分和睡眠评分均较高。CM病人躯体化症状的单险因素分析结果中,受教育年限、头痛程度评分、头痛持续时间、发作频率、病程、失能程度评分、焦虑评分、抑郁评分和睡眠评分为躯体化症状的影响因素。相关因素分析结果显示,头痛程度评分、头痛持续时间、发作频率、病程、失能程度评分、焦虑评分、抑郁评分和睡眠评分是CM病人躯体化症状的危险因素。结论:CM病人伴随躯体化症状较为普遍,头痛程度严重、头痛持续时间长、频繁的头痛发作频率、较长头痛病程、较高失能程度、焦虑、抑郁和睡眠差是CM病人发生躯体化症状的危险因素。 展开更多
关键词 慢性偏头痛 躯体化症状 焦虑 抑郁
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伴躯体症状抑郁症患者磁共振脑灰质体积异常表现
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作者 蒋思雨 董丽平 +3 位作者 童萍 刘晶 姜也 石元洪 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2024年第1期17-22,共6页
目的 采用基于体素的形态学分析(voxel-based morphometry,VBM)比较伴和不伴躯体症状抑郁症患者大脑灰质体积变化,探索伴躯体症状抑郁症患者在MRI上特有表现。方法 纳入52例抑郁症患者,根据入组时健康问卷躯体症状群量表评分是否>9... 目的 采用基于体素的形态学分析(voxel-based morphometry,VBM)比较伴和不伴躯体症状抑郁症患者大脑灰质体积变化,探索伴躯体症状抑郁症患者在MRI上特有表现。方法 纳入52例抑郁症患者,根据入组时健康问卷躯体症状群量表评分是否>9分将其分为伴躯体症状组和不伴躯体症状组,同时纳入性别、年龄匹配的健康志愿者40名作为对照组。所有被试予MRI扫描,采用VBM方法比较各组大脑灰质体积的差异。结果 与对照组相比,伴躯体症状组右颞上回灰质体积增加,右眶额下回、右颞下回、左眶额下回、左颞上回体积减少(P<0.001),不伴躯体症状组右颞中回灰质体积增加,右颞上回、右颞下回体积减少(P<0.01)。抑郁症患者中,伴躯体症状组右舌回、左扣带回的体积较不伴躯体症状组增加(P<0.01)。结论 抑郁症伴躯体症状患者在VBM-MRI上表现为舌回、扣带回体积增加。 展开更多
关键词 抑郁症 躯体症状 灰质体积 基于体素的形态学方法 磁共振成像 舌回 扣带回
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透析患者躯体化症状与抑郁焦虑睡眠障碍心身疾病诊断及实验室指标的相关性分析
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作者 胡汇悦 吴爱华 +2 位作者 沐晓蝶 周华 凌佩瑶 《临床心身疾病杂志》 CAS 2024年第4期16-21,共6页
目的 研究透析患者躯体化症状与睡眠障碍、焦虑、抑郁、心身疾病及实验室指标的关系。方法 收集132例透析患者的一般临床资料和实验室指标数据,采用匹兹堡睡眠质量指数量表(PSQI)、广泛性焦虑障碍-7量表(GAD-7)、患者健康问卷-9抑郁量表... 目的 研究透析患者躯体化症状与睡眠障碍、焦虑、抑郁、心身疾病及实验室指标的关系。方法 收集132例透析患者的一般临床资料和实验室指标数据,采用匹兹堡睡眠质量指数量表(PSQI)、广泛性焦虑障碍-7量表(GAD-7)、患者健康问卷-9抑郁量表(PHQ-9)、健康问卷躯体症状群量表(PHQ-15)、心身研究的诊断标准(DCPR)评估患者的睡眠、焦虑、抑郁、躯体化症状、心身状态。根据PHQ-15评分将入组患者分为观察组63例(有躯体化症状)和对照组69例(无躯体化症状)。比较两组患者一般资料、实验室指标数据和各项量表评分;采用Pearson、Spearman相关分析研究躯体化症状与睡眠障碍、焦虑、抑郁、心身疾病以及各项实验室指标的相关性。结果 两组患者白细胞计数、中性粒细胞计数及血红蛋白、白蛋白水平比较,差异均有统计学意义(P<0.05或0.01)。观察组患者PSQI、PHQ-9、GAD-7评分均高于对照组,综合征诊断个数多于对照组(P<0.01)。Pearson相关分析显示,透析患者PHQ-15评分与中性粒细胞计数呈正相关(P<0.05),与白蛋白呈负相关(P<0.05)。Spearman偏相关分析显示,控制PHQ-9评分、GAD-7评分和综合征诊断个数后,PHQ-15评分与PSQI评分呈正相关(P<0.01);控制PHQ-9评分、PSQI评分和综合征诊断个数后,PHQ-15评分与GAD-7评分呈正相关(P<0.01);控制GAD-7评分、PSQI评分和综合征诊断个数后,PHQ-15评分与PHQ-9评分呈正相关(P<0.01);控制GAD-7评分、PSQI评分和PHQ-9评分后,PHQ-15评分与综合征诊断个数呈正相关(P<0.05)。结论 透析患者躯体化症状与睡眠障碍、焦虑、抑郁、心身疾病诊断情况及患者的中性粒细胞计数、白蛋白水平密切相关。 展开更多
关键词 透析 躯体化症状 睡眠障碍 抑郁 焦虑 心身疾病 白蛋白 中性粒细胞计数
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综合医院儿童精神科联络会诊中躯体化症状障碍患儿焦虑症状、抑郁症状和自我意识的分析
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作者 李桂克 孙华 +2 位作者 孟纲 尤美娜 李南施 《内科》 2024年第2期143-148,共6页
目的探讨综合医院儿童精神科联络会诊中躯体化症状障碍(SSD)患儿的焦虑症状、抑郁症状和自我意识及其影响因素。方法选取83例SSD患儿作为研究对象,依据症状表现分为神经系统症状组(n=44)和消化系统症状组(n=39)。比较两组焦虑症状、抑... 目的探讨综合医院儿童精神科联络会诊中躯体化症状障碍(SSD)患儿的焦虑症状、抑郁症状和自我意识及其影响因素。方法选取83例SSD患儿作为研究对象,依据症状表现分为神经系统症状组(n=44)和消化系统症状组(n=39)。比较两组焦虑症状、抑郁症状和自我意识,应用多因素Logistic回归模型分析SSD患儿自我意识的影响因素。结果神经系统症状组的儿童焦虑性情绪障碍筛查量表总分、社交恐怖因子分和学校恐怖因子分均高于消化系统症状组,消化系统症状组儿童自我意识量表的焦虑因子分高于神经系统症状组(均P<0.05)。多因素Logistic回归模型分析结果显示,人际关系、独生子女、焦虑症状、抑郁症状均是SSD患儿自我意识的影响因素(均P<0.05)。结论综合医院儿童精神科联络会诊中不同症状表现的SSD患儿的焦虑症状和自我意识水平不同,患儿的自我意识跟人际关系、是否独生子女、焦虑症状和抑郁症状均有关,对SSD患儿的治疗应更多关注其情绪状态,提高其自我意识。 展开更多
关键词 躯体化症状障碍 焦虑 抑郁 儿童自我意识量表 联络会诊
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全身免疫炎症指数及躯体化症状评分对首发心梗PCI术后发生院内主要不良心血管事件的预测价值
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作者 郑梦奕 毛家亮 +3 位作者 邹治国 张瑞雷 张厚 李世光 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2024年第3期334-341,共8页
目的·探讨全身免疫炎症指数(systemic immune inflammation index,SII)及躯体化症状评分(somatic symptom scale-China,SSS-CN)对首发急性心肌梗死(acute myocardial infarction,AMI)患者接受经皮冠状动脉介入治疗术(percutaneous ... 目的·探讨全身免疫炎症指数(systemic immune inflammation index,SII)及躯体化症状评分(somatic symptom scale-China,SSS-CN)对首发急性心肌梗死(acute myocardial infarction,AMI)患者接受经皮冠状动脉介入治疗术(percutaneous coronary intervention,PCI)后发生院内主要不良心血管事件(major adverse cardiovascular event,MACE)的预测价值。方法·连续纳入2021年9月至2023年9月就诊于安徽省第二人民医院心内科并接受PCI治疗的首发AMI患者305例。根据患者住院期间是否发生MACE相关事件分为MACEs组(n=203)与非MACEs组(n=102)。对2组患者的性别、年龄、实验室检查结果等资料进行描述性统计分析,并根据分析结果对有统计学意义的项目进行二元Logistic回归检验;进一步绘制受试者操作特征(receiver operating characteristic,ROC)曲线,评估SII及SSS-CN预测院内MACE发生的价值。在此基础上联合冠状动脉syntax评分(syntax score,SS),评价三者联合的预测效能,根据最大约登指数确定诊断的最佳cut-off值。结果·共有203例患者发生MACE事件,其中179例(88.1%)患者发生心力衰竭,16例(7.9%)患者发生严重心律失常,4例(2.0%)患者发生休克,2例(1.0%)患者发生再发心肌梗死,2例(1.0%)患者死亡。与非MACE组相比,MACEs组SII及SSS-CN评分显著升高(1925.86 vs 934.23,38.57 vs 23.30;均P<0.05);二元Logistic回归分析结果提示两者均为MACE发生的独立危险因素。ROC曲线显示:当SII≥952时预测效能最佳,敏感度达64.0%,特异度达62.7%(AUC 0.675,95%CI 0.612~0.737);SSS-CN≥28.5分时预测效能最佳,敏感度达80.7%,特异度达77.5%(AUC 0.840,95%CI 0.794~0.886);联合SS后,三者对MACE的预测效能进一步提高(AUC 0.898,95%CI 0.862~0.933)。结论·首发AMI患者的入院SII及SSS-CN分值为此类患者行PCI术后住院期间发生MACE的独立危险因素,早期监测首发AMI患者PCI术后SII变化,或对有明显躯体化症状的患者及时进行SSS-CN评分能帮助识别院内MACE发生的高危患者。 展开更多
关键词 全身免疫炎症指数 躯体化症状评分 首发急性心肌梗死 主要不良心血管事件 经皮冠状动脉介入治疗术
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MRI检测重度抑郁障碍合并躯体症状大脑灰质的价值分析
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作者 杨胜 蒋烈夫 李新 《生物医学工程学进展》 CAS 2024年第3期191-196,共6页
目的探讨磁共振成像(Magnetic Resonance Imaging,MRI)检测重度抑郁障碍(Major Depressive Disorder,MDD)合并躯体症状的临床价值。方法选取2022年12月至2023年9月本院收治的MDD合并躯体症状患者127例作为研究对象,按健康问卷躯体症状... 目的探讨磁共振成像(Magnetic Resonance Imaging,MRI)检测重度抑郁障碍(Major Depressive Disorder,MDD)合并躯体症状的临床价值。方法选取2022年12月至2023年9月本院收治的MDD合并躯体症状患者127例作为研究对象,按健康问卷躯体症状群量表(Patient Health Questionnaire-15,PHQ-15)评分分成不伴躯体症状组(简称A组,总分:PHQ-15≥10分)和伴躯体症状组(简称B组,总分:PHQ-15<5分),两组分别有46例、81例,同时选取67名健康体检者作为参照对象。使用3.0MRI扫描仪进行扫描。利用VBM8软件包进行磁共振数据预处理,对比大脑灰质的体积差异。结果3组的PHQ-15评分、HAMD-24评分对比差异显著(P<0.05)。其中B组PHQ-15评分与A组PHQ-15评分略有差异,但差异不显著(P>0.05)。抑郁症组与健康对照组间的VBM分析显示,A组、B组右颞下回脑区和左颞上回脑区的体积较对照组减小;A组、B组右颞中回、左距状裂所在脑区体积较对照组增大。其中B组右眶额下回体素数目显著低于A组(P<0.001)。B组右颞中回、左距状裂的体素数目较A组显著增大(P<0.05)。结论相较于不伴躯体症状的抑郁症患者,伴有躯体症状的抑郁症患者经MRI检测可发现更多大脑灰质结构的变化。这些大脑结构的异常可能是导致抑郁症患者出现各种躯体症状的神经基础。 展开更多
关键词 MRI 重度抑郁障碍合并躯体症状 躯体症状 PHQ-15
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度洛西汀联合盐酸舍曲林治疗老年抑郁症的疗效
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作者 张馨媛 郭胡丽 +3 位作者 郝俊慧 孙夏昭 原鹏韬 徐心田 《西北药学杂志》 CAS 2024年第4期181-185,共5页
目的研究度洛西汀联合盐酸舍曲林治疗伴躯体症状老年抑郁症患者的临床疗效。方法对收治的102例伴躯体症状的老年抑郁症患者进行研究,采用投掷法分为对照组和观察组,各51例。对照组使用度洛西汀治疗,观察组在对照组治疗的基础上联合盐酸... 目的研究度洛西汀联合盐酸舍曲林治疗伴躯体症状老年抑郁症患者的临床疗效。方法对收治的102例伴躯体症状的老年抑郁症患者进行研究,采用投掷法分为对照组和观察组,各51例。对照组使用度洛西汀治疗,观察组在对照组治疗的基础上联合盐酸舍曲林治疗,比较2组患者的临床疗效、焦虑与抑郁状态、实验室指标和不良反应发生情况等。结果观察组临床治疗总有效率(96.08%)明显高于对照组(80.39%),P<0.05;治疗后,2组患者老年抑郁量表(geriatric depression scale,GDS)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)和汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分均降低,且观察组明显低于对照组(P<0.05);观察组治疗后1、3、6周不良反应评分(treatment emergent symptom scale,TESS)均低于对照组(P<0.05),且组间、各时间点比较差异均有统计学意义(P<0.05);治疗后,观察组5-羟色胺(5-hydroxytryptamine,5-HT)和脑源性神经营养因子(brainderived neurotrophic factor,BDNF)水平高于对照组(P<0.05),去甲肾上腺素(norepinephrine,NE)水平低于对照组(P<0.05);2组患者的不良反应发生率分别为13.73%、17.65%,组间比较差异无统计学意义。结论度洛西汀联合盐酸舍曲林治疗伴躯体症状老年抑郁症患者疗效明显,患者焦虑、抑郁状态明显改善,血清神经递质水平明显改善,且无明显不良反应发生,安全性良好。 展开更多
关键词 度洛西汀 盐酸舍曲林 伴躯体症状老年抑郁症 临床疗效 不良反应
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新型冠状病毒感染患者潜在的胃肠道症状与心理健康状况相关性研究
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作者 潘雪 苏暾 +1 位作者 陆建萍 黄文 《海军医学杂志》 2024年第9期969-972,共4页
目的 探讨新型冠状病毒感染(COVID-19)患者出现的慢性胃肠道症状与焦虑和抑郁等心理健康状况的相关性。方法 设计一组有关胃肠道症状及心理健康问题的调查问卷,于2023年7月1日至2023年9月1日对326名在海军军医大学第一附属医院消化内科... 目的 探讨新型冠状病毒感染(COVID-19)患者出现的慢性胃肠道症状与焦虑和抑郁等心理健康状况的相关性。方法 设计一组有关胃肠道症状及心理健康问题的调查问卷,于2023年7月1日至2023年9月1日对326名在海军军医大学第一附属医院消化内科门诊就诊的有COVID-19病史的患者进行随机调查。结果 从调查问卷的平均得分来看,患者在感染期间和感染后均表现出躯体症状(PHQ-15=5~9分)和健康焦虑(SHAI>15分)状态,有胃肠道疾病史(P<0.05)和健康焦虑(P<0.001)的患者胃肠道症状发生更加频繁。患者感染期间的躯体状况及胃肠道症状更差(P=0.003),抑郁症状更严重(P=0.004),在感染期间感到不适和在感染之后出现胃肠道症状的患者更有可能出现焦虑症状。结论 COVID-19能增加胃肠道症状的发生频率和抑郁的发生,健康焦虑对胃肠道症状的发生有影响,这为认知行为疗法可能对胃肠门诊患者有益提供证据,并为消化道疾病的治疗提供了新的视角。 展开更多
关键词 心理健康状况 抑郁 焦虑 胃肠道症状 躯体症状 新型冠状病毒感染
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柴胡疏肝汤联合无抽搐电休克在女性躯体化障碍患者中的应用分析
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作者 陈晓敏 何君珍 吴惠玲 《辽宁中医杂志》 CAS 北大核心 2024年第7期68-71,共4页
目的 探究柴胡疏肝汤联合无抽搐电休克(MECT)在女性躯体化障碍患者中的应用效果。方法 将2021年6月—2022年6月该院收治的84例女性躯体化障碍患随机分为对照组42例和试验组42例。对照组予以MECT联合常规西药治疗,试验组在对照组基础上... 目的 探究柴胡疏肝汤联合无抽搐电休克(MECT)在女性躯体化障碍患者中的应用效果。方法 将2021年6月—2022年6月该院收治的84例女性躯体化障碍患随机分为对照组42例和试验组42例。对照组予以MECT联合常规西药治疗,试验组在对照组基础上联合柴胡疏肝汤治疗。比较两组治疗前后临床症状、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评分、症状自评量表(SCL-90)各因子评分,评价两组的临床疗效及安全性。结果 治疗后两组临床症状均减轻,且试验组临床症状较对照组缓解更显著(P<0.05);治疗后,两组HAMD、HAMA评分均降低,且试验组低于对照组(P<0.05);治疗后,两组SCL-90各因子评分均降低,且试验组低于对照组(P<0.05);试验组的临床疗效优于对照组(P<0.05);两组不良反应总发生率比较差异不明显(P>0.05)。结论 对女性躯体化障碍患者应用柴胡疏肝汤联合MECT治疗,可显著改善患者的临床症状,缓解其神经症状,促进其病情转归,提升其治疗效果,且安全性高。 展开更多
关键词 女性躯体化障碍 柴胡疏肝汤 无抽搐电休克 临床症状 神经症状 疗效 安全性
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