Epidemic Characteristics and Spatio-Temporal Patterns of HFRS in Qingdao City,China,2010-2022

Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFRS)in Qingdao City,China.Methods Information was collected on HFRS cases in Qingdao City from 2010 to 2022.Descriptive epidemiologic,seasonal decomposition,spatial autocorrelation,and spatio-temporal cluster analyses were performed.Results A total of 2,220 patients with HFRS were reported over the study period,with an average annual incidence of 1.89/100,000 and a case fatality rate of 2.52%.The male:female ratio was 2.8:1.75.3%of patients were aged between 16 and 60 years old,75.3%of patients were farmers,and 11.6%had both“three red”and“three pain”symptoms.The HFRS epidemic showed two-peak seasonality:the primary fall-winter peak and the minor spring peak.The HFRS epidemic presented highly spatially heterogeneous,street/township-level hot spots that were mostly distributed in Huangdao,Pingdu,and Jiaozhou.The spatio-temporal cluster analysis revealed three cluster areas in Qingdao City that were located in the south of Huangdao District during the fall-winter peak.Conclusion The distribution of HFRS in Qingdao exhibited periodic,seasonal,and regional characteristics,with high spatial clustering heterogeneity.The typical symptoms of“three red”and“three pain”in patients with HFRS were not obvious.

Spatio-temporal patterns of drought in North Xinjiang, China, 1961–2012 based on meteorological drought index

Drought, which is one of the most frequently occurring severe hazards with long time scales and cov- ering wide geographical areas, is a natural phenomenon resulting in significant economic losses in agriculture and industry. Drought is caused by an imbalance between the inputs of and the demand for water which is insufficient to meet the demands of human activities and the eco-environment. As a major arid and semi-arid area and an important agricultural region in Northwest China, North Xinjiang （NX） shows great vulnerability to drought. In this paper, the characteristics of inter-annual and seasonal drought were analyzed in terms of drought occurrence and drought coverage, by using the composite index of meteorological drought and the data of daily precipitation, air temperature, wind speed, relative humidity and sunshine duration from 38 meteorological stations during the period 1961-2012. Trend analysis, wavelet analysis and empirical orthogonal function were also applied to investigate change trend, period and regional characteristics, respectively. In NX, annual and seasonal drought occurrence and drought coverage all showed a decreasing trend that was most significant in winter （with rates of-0.26 month/10a and -15.46%, respectively）, and drought occurrence in spring and summer were more frequent than that in autumn and winter. Spatially, drought was severe in eastern regions but mild in western regions of NX. Annual and seasonal drought occurrence at 38 meteorological stations displayed decreasing trends and were most significant in ＂Shi- hezi-Urumqi-Changji＂, which can help to alleviate severe drought hazards for local agricultural production and improve human livelihood. NX can be approximately classified into three sub-regions （severe drought region, moder- ate drought region and mild drought region）, which were calculated from annual drought frequencies. The cross wavelet transform suggested that SOl （Southern Oscillation Index）, AOI （Arctic Oscillation Index）, AAOI （Antarctic Oscillation Index）, PAOI （Pacific/North American Oscillation Index） and NAOI （North Atlantic Oscillation Index） have significant correlation with the variation of drought occurrence in NX. To prevent and mitigate the occurrence of drought disasters in NX, agricultural and government managers should pay more attention to those drought events that occur in spring and summer.

Spatio-temporal patterns of land use change along the Bohai Rim in China during 1985-2005

Based on TM image data and other survey materials, this paper analyzed the spatiotemporal patterns of land use change in the Bohai Rim during 1985-2005. The findings of this study are summarized as follows： （1） Land use pattern changed dramatically during 1985-2005. Industrial and residential land in urban and rural areas increased by 643,946 hm2 of which urban construction land had the largest and fastest increase of 294,953 hm2 at an annual rate of 3.72%. （2） The outward migration of rural population did not prevent the expansion of residential land in rural areas by 184,869 hm2. This increase reveals that construction of rural residences makes seriously wasteful and inefficient use of land. （3） Arable land, woodland and grassland decreased at a rate of -0.02%, -0.12% and -1.32% annually, while unused land shrank by 157,444 hm^2 at an annual rate of -1.69%. （4） The change of land use types showed marked fluctuations over the two stages （1985-1995 and 1995-2005） In particular, arable land, woodland and unused land experienced an inversed trend of change. （5） There was a significant interaction between arable land and woodland, industrial construction land in urban and rural areas showed a net trend of increase during the earlier period, but only adjustment to its internal structure during the second period. The loss of arable land to the construction of factories, mines and residences took place mainly in the fringe areas of large and medium-sized cities, along the routes of major roads, as well as in the economically developed coastal areas in the east. Such changes are closely related to the spatial differentiation of the level of urbanization and industrialization in the region.

Spatio-Temporal Patterns of Wildlife Road Mortality in Golestan National Park-North East of Iran

Nowadays, wildlife road mortality is acknowledged as a main source of threatening long-term survival of wildlife. This paper as the first to analysis wild life vehicle collisions in Iran, aims to reconstruct and interpret the spatio-temporal patterns of WVCs on Asiaei highway in Golestan National Park (GNP). With the collaboration of environmental protection department of GNP, we identified about 1900 WVC Records involving 34 different species of mammals, birds, reptiles and amphibians between 2004 and 2013. Mammals were involved in more than 50% of overall WVCs, among which wild boar (Sus scrofa), Golden Jackal (Canis aureus), Red Fox (Vulpes vulpes), hedgehog (Erinaceus concolor), stone marten (Martes foina) and porcupine (Hystrix indica) were involved in more than 90% of mammals’ mortalities;So, we focused on analyzing spatio-temporal pattern of vehicle collisions of these six mammal species. During the study period, these species have undergone 95% increase in road mortalities, averagely. Detailed temporal analyses exhibited an increasing trend of road mortalities from spring to summer and then a reducing one to late winter. It was shown that a large number of collisions occurred in holiday periods when recreational trips considerably increased the traffic volume of Asiaei highway. Preliminary inspection of spatial patterns using Kernel density analysis revealed six collision hotspots, mostly located in the road bends with densely forested land cover on both sides;the promenades along the road seemed to play a significant role too. Scale dependency analyses of collision patterns, demonstrated clustering pattern at micro scales less than 10 km, randomness at meso scales 10 - 20 km and both regularity and clustering at macro scales more than 20 km. This paper suggests that road mortality of common species in GNP is a momentous issue, which needs to be considered by relevant governmental and public organizations. We also emphasize that the analyses of spatial and temporal patterns of WVCs are fundamentals to plan for mitigate wildlife road mortality.

Unravel the spatio-temporal patterns and their nonlinear relationship with correlates of dockless shared bikes near metro stations

The dockless bike-sharing system has rapidly expanded worldwide and has been widely used as an intermodal transport to connect with public transportation.However,higher flexibility may cause an imbalance between supply and demand during daily operation,especially around the metro stations.A stable and efficient rebalancing model requires spatio-temporal usage patterns as fundamental inputs.Therefore,understanding the spatio-temporal patterns and correlates is important for optimizing and rescheduling bike-sharing systems.This study proposed a dynamic time warping distance-based two-dimensional clustering method to quantify spatio-temporal patterns of dockless shared bikes in Wuhan and further applied the multiclass explainable boosting machine to explore the main related factors of these patterns.The results found six patterns on weekdays and four patterns on weekends.Three patterns show the imbalance of arrival and departure flow in the morning and evening peak hours,while these phenomena become less intensive on weekends.Road density,living service facility density and residential density are the top influencing factors on both weekdays and weekends,which means that the comprehensive impact of built-up environment attraction,facility suitability and riding demand leads to the different usage patterns.The nonlinear influence universally exists,and the probability of a certain pattern varies in different value ranges of variables.When the densities of living facilities and roads are moderate and the relationship between job and housing is relatively balanced,it can effectively promote the balanced usage of dockless shared bikes while maintaining high riding flow.The spatio-temporal patterns can identify the associated problems such as imbalance or lack of users,which could be mitigated by corresponding solutions.The relative importance and nonlinear effects help planners prioritize strategies and identify effective ranges on different patterns to promote the usage and efficiency of the bike-sharing system.

Practice patterns among ophthalmic surgeons in treating concomitant oculoplastic conditions in preoperative period:A questionnaire-based study

BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no research.AIM To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic intervention.METHODS A cross-sectional survey was disseminated among ophthalmologists all over India.The survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up patterns.RESULTS A total of 180 ophthalmologists responded to the survey.Most practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was advised.The most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid surgeries.Sixty-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease patients.CONCLUSION Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular conditions.Many ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract surgery.Eyelid conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.

Spatio-temporal evolution analysis of landscape pattern and habitat quality in the Qinghai Province section of the Yellow River Basin from 2000 to 2022 based on InVEST model

Habitat quality is an important indicator for evaluating the quality of ecosystem.The Qinghai Province section of the Yellow River Basin plays an important role in the ecological protection of the upper reaches of the Yellow River Basin.To comprehensively analysis the alterations of habitat quality in the Qinghai Province section of the Yellow River Basin,this study utilized the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model to calculate the habitat quality index and analyze the spatio-temporal variation characteristics of habitat quality in the study area from 2000 to 2022,and calculated seven landscape pattern indices(number of patches,patch density,largest patch index(LPI),landscape shape index(LSI),contagion index(CONTAG),Shannon diversity index,and Shannon evenness index)to research the variation of landscape pattern in the study area.The results showed that the number of patches,patch density,LPI,LSI,Shannon diversity index,and Shannon evenness index increased from 2000 to 2022,while the CONTAG decreased,indicating that the landscape pattern in the Qinghai Province section of the Yellow River Basin changed in the direction of distribution fragmentation,shape complexity,and heterogeneity.The average value of the habitat quality index in the Qinghai Province section of the Yellow River Basin from 2000 to 2022 was 0.90.Based on the value of habitat quality index,we divided the level of habitat quality into five categories:lower(0.00-0.20),low(0.20-0.40),moderate(0.40-0.60),high(0.60-0.80),and higher(0.80-1.00).Most areas were at the higher habitat quality level.The lower habitat quality patches were mainly distributed in Longyang Gorge and Yellow River-Huangshui River Valley.From 2000 to 2022,the habitat quality in most areas was stable;the increase areas were mainly distributed in Guinan County,while the decrease areas were mainly distributed in Xining City,Maqen County,Xinghai County,Qumarleb County,and Darlag County.To show the extent of habitat quality variation,we calculated Sen index.The results showed that the higher habitat quality area had a decrease trending,while other categories had an increasing tendency,and the decreasing was faster than increasing.The research results provide scientific guidance for promoting ecological protection and high-quality development in the Qinghai Province section of the Yellow River Basin.

Spatio-temporal patterns of drought evolution over the Beijing-Tianjin-Hebei region, China

Spatio-temporal patterns of drought from 1961 to 2013 over the Beijing-Tianjin-Hebei(BTH) region of China were analyzed using the Palmer Drought Severity index(PDSI) based on 21 meteorological stations. Overall, changes in the mean-state of drought detected in recent decades were due to decreases in precipitation and potential evapotranspiration. The Empirical Orthogonal Functions(EOF) method was used to decompose drought into spatio-temporal patterns, and the first two EOF modes were analyzed. According to the first leading EOF mode(48.5%), the temporal variability(Principal Components, PC1) was highly positively correlated with annual series of PDSI(r=+0.99). The variance decomposition method was further applied to explain the inter-decadal temporal and spatial variations of drought relative to the total variation. We find that 90% of total variance was explained by time variance, and both total and time variance dramatically decreased from 1982 to 2013. The total variance was consistent with extreme climate events at the inter-decadal scale(r=0.71, p<0.01). Comparing the influence of climate change on the annual drought in two different long-term periods characterized by dramatic global warming(P1: 1961–1989 and P2: 1990–2013), we find that temperature sensitivity in the P2 was three times more than that in the P1.

Spatio-temporal patterns and changes in environmental attitudes and place attachment in Gauteng, South Africa

In this study,we employed a number of geospatial techniques to examine the spatiotemporal patterns and changes of environmental attitudes and place attachment values in the Gauteng province of South Africa.The data were obtained from the Gauteng City Region Observatory’s Quality of Life Survey collected at three separate points in time,namely 2013,2015,and 2017.Results indicated that wards(smallest administrative and analysis units)located on the urban periphery of Gauteng,which are generally less affluent,largely held more negative environmental attitudes and place attachment values during the three time periods.In contrast,centrally located wards,which are generally more affluent,expressed more positive environmental attitudes but less place attachment values,especially in 2017.The findings of this research not only highlight the complex spatio-temporal distribution of environmental attitudes and place attachment values throughout Gauteng but also empha-size the need for spatially targeted state interventions for future environmental planning within the province.

Tracking the in vivo spatio-temporal patterns of neovascularization via NIR-II fluorescence imaging

The in vivo spatio-temporal patterns of neovascularization are still poorly understood because it is limited to multi-scale techniques from the cellular level to living animal level.Owing to deep tissue-penetration and zero autofluorescence background,the second near-infrared(NIR-II,1,000–1,700 nm)fluorescence imaging recently shows promise in breaking through this dilemma by dynamically tracking the pathophysiological process of neovascularization in vivo.Here,NIR-II fluorescence imaging was recruited for monitoring blood vessels in order to visualize the vascular injury and quantitively assess neovascularization in mouse models of acute skeleton muscle contusion and hindlimb ischemia.The temporal analysis of real-time NIR-II fluorescence intensity demonstrated that the blood flow perfusion of ischemia area was able to rapidly restore to 96%of pre-ischemic state within one week.Moreover,the spatial analysis revealed that the lower and outer quadrants of ischemia area in the mouse model of hindlimb ischemia always had relatively high blood flow perfusion compared with other quadrants during three weeks post-ischemia,and even exceeded pre-ischemic quantity at 21 days post-ischemia.In conclusion,this in vivo imaging technique has significant potential utility for studying the spatio-temporal patterns of neovascularization in vivo.

Analysis on the Spatio-temporal Patterns of Water Conservation Services in Beijing

The shortage of water resources is a key factor limiting the sustainable development of the economy and society in Beijing. This study analysed the spatiotemporal patterns of Beijing’s water conservation services(WCS) based on the water balance equation at multiple scales, including city, main functional areas and key districts and counties, determined the differences in the water conservation amount among different land cover types and investigated the reasons for the spatiotemporal differences in the water conservation amount. The results indicated that:(1) compared to 2005, water conservation amount increased substantially in 2010. However, the overall water conservation capacity was low.(2) Among the various land cover types in Beijing, the average water conservation capacity decreased in the following order: wetland, forest, grassland, cropland, bare land and artificial surface.(3) The average water conservation amount in the main functional areas of Beijing varied substantially and was positive only in the ecological conservation area(ECA).(4) The water conservation capacity of each district and county varied substantially within ECA, among which the contribution of the forest in Miyun District, Huairou District and Pinggu District was the highest. The changes in the spatiotemporal patterns of Beijing’s WCS were the synthetic effects of changes in the land covers and meteorological conditions. This study is helpful in achieving the sustainable utilization of water resources in Beijing.

Spatio-temporal patterns and driving mechanism of farmland fragmentation in the Huang-Huai-Hai Plain

Exploring the spatio-temporal variations of farmland landscape patterns in a traditional agricultural region can provide scientific support for decision-making on sustainable rural land use and rural vitalization development. This study established a comprehensive evaluation index for farmland fragmentation with multiple aspects(dominance, integrity, aggregation, regularity, and connectivity) at the county scale. The goal was to identify the evolution of farmland fragmentation in the traditional agricultural region of the Huang-Huai-Hai Plain during 2000–2015 and investigate underlying drivers using panel data of 359 counties.Results showed an accelerating but fluctuating fragmentation pattern of the farmland landscape. The indexes of dominance, integrity, and aggregation of farmland decreased most sharply, while the index of connectivity increased. Furthermore, the evolution of the farmland fragmentation pattern showed significant spatio-temporal heterogeneity, which is similar to the trajectory of urbanization and land use transition. Farmland fragmentation in municipal districts also emerged earlier and was more severe than in county-level cities and counties.Factors influenced by advancing urbanization include the proportion of artificial land, population density, and proportion of primary industry;these factors drove the evolution of farmland fragmentation. In contrast, the increase in income of rural residents and production efficiency of farmland were the key factors contributing to the improvement in farmland connectivity.

Annual spatio-temporal migration patterns of Hooded Cranes wintering in Izumi based on satellite tracking and their implications for conservation

Background: The Hooded Crane(Grus monacha) is listed as a vulnerable species by IUCN. Knowledge about the migration of the Hooded Crane is still limited. Here we reported the spatio-temporal migration patterns of Hooded Cranes wintering in Izumi, Japan, as well as important stopover areas for their conservation.Methods: Four adult and five subadult cranes, all wintering in Izumi, Japan, were fitted with satellite transmitters(GPS–GSM system) at their stopover sites in northeastern China in 2014 and 2015. We analyzed the time and duration of adults and subadults in spring and autumn migration, as well as the time and duration they stayed in breeding and wintering ground. In addition, we analyzed the land use of the cranes in stopover areas.Results: Adult cranes took much longer time to migrate both north in spring(mean days) compared with subadult cranes(15.3 and 5.2 days, respectively). H= 44.3 days) and south in fall(mean = 54.0 owever, the subadults had longer wintering(mean = 149.8 days) and nomadic(breeding season for adults) seasons(mean d with adults(133.8 and 122.3 days, respectively). Three important stopover areas have been= 196.8 days) compare identified: the region around Muraviovka Park in Russia, the Songnen Plain in China, and the west coast of South Korea, where cranes spent most of their migration time(62.2 and 85.7% in spring and autumn, respectively). During migration, nomadic period and winter, Hooded Cranes usually stay in croplands for resting and feeding. In non-wintering season, less than 6% of stopover sites were located within protected areas.Conclusion: Overall, our results contribute to understanding the annual spatio-temporal migration patterns of Hooded Cranes in the eastern flyway, and planning conservation measures for this species.

Multi-scale regionalization based mining of spatio-temporal teleconnection patterns between anomalous sea and land climate events

Climate sequences can be applied to defining sensitive climate zones, and then the mining of spatio-temporal teleconnection patterns is useful for learning from the past and preparing for the future. However, scale-dependency in this kind of pattern is still not well handled by existing work. Therefore, in this study, the multi-scale regionalization is embedded into the spatio-temporal teleconnection pattern mining between anomalous sea and land climatic events. A modified scale-space clustering algorithm is first developed to group climate sequences into multi-scale climate zones. Then, scale variance analysis method is employed to identify climate zones at characteristic scales, indicating the main characteristics of geographical phenomena. Finally, by using the climate zones identified at characteristic scales, a time association rule mining algorithm based on sliding time windows is employed to discover spatio-temporal teleconnection patterns. Experiments on sea surface temperature, sea level pressure, land precipitation and land temperature datasets show that many patterns obtained by the multi-scale approach are coincident with prior knowledge, indicating that this method is effective and reasonable. In addition, some unknown teleconnection patterns discovered from the multi-scale approach can be further used to guide the prediction of land climate.

The Spatio-temporal Patterns of Macro Benthos Functional Groups and the Associated Factors Affecting Them after Wetland Restoration

This study examines how the spatiotemporal patterns of functional groups of macro benthos responded to coastal wetland restoration projects. Compared with the traditional single-species approach, methods for identifying functional groups of macro benthos more comprehensively reflect the states of the wetland, i.e., spatiotemporal patterns and the related influencing factors. In this study, the macro benthos samples, soil samples, and plant samples were collected at each same sample site in April, July, and October of 2017 and January of 2018. After classification of the macro benthos functional groups according to some traits, the factors influencing the functional groups were examined by a linear stepwise regression. The results showed that all macro benthos were classified into 11 different functional groups based on their traits of forms of locomotion, feeding habits, and food gathering methods. The semi-mobile suspensivores(FDX), semi-mobile surface detritivores(SDX), and Jawed mobile carnivores(CMJ) were the main groups observed in a year. Regression analysis showed that particle size,moisture content, and plant height were important common factors influencing most groups. The main influencing factor of FDX was particle size(P=0.020). Moisture content(P=0.004), plant cover degree(P=0.008), and particle size(P=0.032) comprised the main restrictions of SDX in summer. Soil salinity(P=0.040) and plant height(P=0.011)were the factors influencing CMJ in autumn and winter. This study shows the changing characteristics of macro benthos functional groups to promote coastal wetland restoration and future biogeomorphological studies.

Spatio-Temporal Variations in Co-Occurrence Patterns of Fish Communities in Haizhou Bay, China: Null Model Analysis

Co-occurrence pattern of fish species plays an important role in understanding the spatio-temporal structure and the stability of fish community.Species coexistence may vary with time and space.The co-occurrence patterns of fish species were examined using the C-score under fixed-fixed null model for fish communities in spring and autumn over different years in the Haizhou Bay,China.The results showed that fish assemblages in the whole bay had non-random patterns in spring and autumn over different years.However,the fish co-occurrence patterns were different for the northern and southern fish assemblages in spring and autumn.The northern fish assemblage showed structured pattern,whereas the southern assemblage were randomly assembled in spring.The co-occurrence patterns of fish communities were relatively stable over different years,and the number of significant species pairs in northern assemblage was more than that in the southern assemblage.Environmental heterogeneity played an important role in determining the distributions of fish species that formed significant species pairs,which might affect the co-occurrence patterns of northern and southern assemblages further in the Haizhou Bay.

Implementing geostatistical analysis to study spatio-temporal distribution patterns of swimming crabs(Portunus trituberculatus)

This study attempted to compare the performance of local polynomial interpolation,inverse distance weighted interpolation,and ordinary kriging in studying distribution patterns of swimming crabs.Cross-validation was used to select the optimum method to get distribution results,and kriging was used for making spatial variability analysis.Data were collected from 87 sampling stations in November of 2015(autumn)and February(winter),May(spring)and August(summer)of 2016.Results indicate that swimming crabs widely distributed in autumn and summer:in the summer,they were more spatially independent,and resources in each sampling station varied a lot;in the winter and spring,the abundance of crabs was much lower,but the individual crab size was bigger,and they showed the patchy and more concentrative distribution pattern,which means they were more spatially dependent.Distribution patterns were in accordance with ecological migration features of swimming crabs,which were affected by the changing marine environment.This study could infer that it is applicable to study crab fishery or even other crustacean species using geostatistical analysis.It not only helps practitioners have a better understanding of how swimming crabs migrate from season to season,but also assists researchers in carrying out a more comprehensive assessment of the fishery.Therefore,it may facilitate advancing the implementation in the pilot quota management program of swimming crabs in northern Zhejiang fishing grounds.

Spatio-temporal point pattern analysis on Wenchuan strong earthquake

For exploring the aftershock occurrence process of the 2008 Wenchuan strong earthquake, the spatio-temporal point pattern analysis method is employed to study the sequences of aflershocks with magnitude M≥4.0, M≥4.5, and M≥5.0. It is found that these data exhibit the spatio-temporal clustering on a certain distance scale and on a certain time scale. In particular, the space-time interaction obviously strengthens when the distance is less than 60 km and the time is less than 260 h for the first two aftershock sequences; however, it becomes strong when the distance scale is less than 80 km and the time scale is less than 150 h for the last aftershock sequence. The completely spatial randomness analysis on the data regardless of time component shows that the spatial clustering of the aftershocks gradually strengthens on the condition that the distance is less than 60 km. The results are valuable for exploring the occurrence rules of the Wenchuan strong earthquake and for predicting the aftershocks.

Clinical manifestation,lifestyle,and treatment patterns of chronic erosive gastritis:A multicenter real-world study in China

BACKGROUND Although chronic erosive gastritis(CEG)is common,its clinical characteristics have not been fully elucidated.The lack of consensus regarding its treatment has resulted in varied treatment regimens.AIM To explore the clinical characteristics,treatment patterns,and short-term outcomes in CEG patients in China.METHODS We recruited patients with chronic non-atrophic or mild-to-moderate atrophic gastritis with erosion based on endoscopy and pathology.Patients and treating physicians completed a questionnaire regarding history,endoscopic findings,and treatment plans as well as a follow-up questionnaire to investigate changes in symptoms after 4 wk of treatment.RESULTS Three thousand five hundred sixty-three patients from 42 centers across 24 cities in China were included.Epigastric pain(68.0%),abdominal distension(62.6%),and postprandial fullness(47.5%)were the most common presenting symptoms.Gastritis was classified as chronic non-atrophic in 69.9%of patients.Among those with erosive lesions,72.1%of patients had lesions in the antrum,51.0%had multiple lesions,and 67.3%had superficial flat lesions.In patients with epigastric pain,the combination of a mucosal protective agent(MPA)and proton pump inhibitor was more effective.For those with postprandial fullness,acid regurgitation,early satiety,or nausea,a MPA appeared more promising.CONCLUSION CEG is a multifactorial disease which is common in Asian patients and has non-specific symptoms.Gastroscopy may play a major role in its detection and diagnosis.Treatment should be individualized based on symptom profile.

Extreme Meteorological Drought Events over China(1951-2022):Migration Patterns,Diversity of Temperature Extremes,and Decadal Variations

Recently,extreme meteorological droughts have affected China,causing terrible socioeconomic impacts.Despite previous research on the spatiotemporal characteristics and mechanisms of drought,two crucial issues remain seldom explored.First,an event-oriented drought chronology with detailed spatiotemporal evolutions is urgently required.Second,the complex migration patterns and diversity of synchronous temperature extremes need to be quantitatively investigated.Accordingly,the main achievements of our investigation are as follows.We produced an event-oriented set of extreme meteorological droughts over China through the application of a newly developed 3D DBSCAN-based detection method(deposited on https://doi.org/10.25452/figshare.plus.25512334),which was verified with a historical atlas and monographs on a case-by-case basis.In addition,distinctive migration patterns(i.e.,stationary/propagation types)are identified and ranked,considering the differences in latitudinal zones and coastal/inland locations.We also analyze the diversity of synchronous temperature extremes(e.g.,hotness and coldness).Notably,an increasing trend in hot droughts occurred over China since the late 1990s,predominantly appearing to the south of 30°N and north of 40°N.All drought events and synchronous temperature extremes are ranked using a comprehensive magnitude index,with the 2022 summer-autumn Yangtze River hot drought being the hottest.Furthermore,Liang-Kleeman information flow-based causality analysis emphasizes key areas where the PDO and AMO influenced decadal variations in coverages of droughts and temperature extremes.We believe that the achievements in this study may offer new insights into sequential mechanism exploration and prediction-related issues.