Purpose: Commonly used diffusion weighted (DW) imaging such as DW spin echo (SE) type echo planar imaging (DW-SE-EPI) is known to be a snapshot-like acquisition and to have a relatively high signal-to-noise ratio. Spi...Purpose: Commonly used diffusion weighted (DW) imaging such as DW spin echo (SE) type echo planar imaging (DW-SE-EPI) is known to be a snapshot-like acquisition and to have a relatively high signal-to-noise ratio. Spiral MRI sequence (SPIRAL) has characteristics similar to these of EPI, but it has rarely been used for diffusion-weighted imaging (DWI). In vivo DW-SPIRAL of the rat brain has almost never been reported. Our purpose in this study was to examine the potential of SE-type two-dimensional (2D) multi-shot spiral acquisition MRI for apparent diffusion coefficient (ADC) mapping of the rat brain in vivo. Materials and Methods: We made an SE-type DW-2D-spiral MRI sequence (DW-SPIRAL) which was prepared on a 2.0-T animal-experiment MR scanner. Comparing the phantom experimental result of DW-SPIRAL with the phantom experimental result of DW SE-type echo-planar imaging (DW-SE-EPI) and conventional DW spin echo imaging (DW-SE), we estimated the characteristics of DW-SPIRAL and assessed the clinical application of DW-SPIRAL in an animal experiment on the rat brain. Results: There was not much difference between the calculated water/glycerol phantom diffusion coefficient of DW-SPIRAL and the calculated diffusion coefficient of DW-SE. This result shows that the DW-SPIRAL sequence is appropriate for use in diffusion weighted imaging. There were fewer phantom image distortions and ghosting artifacts with DW-SPIRAL than with DW-SE-EPI, and this tendency was similar in the animal experiment on the rat brain. Conclusion: The DW-SPIRAL sequence had been successfully tested in phantom experiments and rat brain experiments. It has been demonstrated that the DW-SPIRAL sequence is capable of producing in vivo rat brain DWI.展开更多
目的探讨MRI多序列成像在肝硬化背景下小肝癌诊断和微血管侵犯评估中的应用价值。方法选择2020年9月~2022年9月在我院接受诊断的80例疑似小肝癌的患者为研究对象,均采用西门子3.0 T Verio超导型磁共振扫描仪检查,分析MRI多序列成像对肝...目的探讨MRI多序列成像在肝硬化背景下小肝癌诊断和微血管侵犯评估中的应用价值。方法选择2020年9月~2022年9月在我院接受诊断的80例疑似小肝癌的患者为研究对象,均采用西门子3.0 T Verio超导型磁共振扫描仪检查,分析MRI多序列成像对肝硬化背景下小肝癌诊断和微血管侵犯评估中的应用价值,以肝脏穿刺活检为金标准,采用Kappa一致性检验,分析MRI多序列成像在小肝癌诊断和微血管侵犯的一致性。结果80例疑似小肝癌患者经病理确诊36例,未发生肝癌44例。T2WI诊断敏感度为83.33%,特异度为79.55%,准确度为81.25%,Kappa值为0.624;T1WI诊断敏感度为77.78%,特异度为81.82%,准确度为80.00%,,Kappa值为0.596;LAVA诊断敏感度为83.33%,特异度为81.82%,准确度为82.50%,Kappa值为0.648;联合诊断敏感度为94.44%,特异度为77.27%,准确度为85.00%,Kappa值为0.703。36例疑似小肝癌患者经病理确诊MVI 7例,未发生MVI 29例。T2WI诊断敏感度为71.43%,特异度为86.21%,准确度为83.33%,Kappa值为0.520;T1WI诊断敏感度为71.43%,特异度为82.76%,准确度为80.56%,Kappa值为0.466;LAVA诊断敏感度为71.43%,特异度为89.66%,准确度为86.11%,Kappa值为0.579;联合诊断敏感度为85.71%,特异度为82.76%,准确度为83.33%,Kappa值为0.563。结论MRI多序列成像有助于提高肝硬化背景下小肝癌的诊断和微血管侵犯的评估,具有良好的应用价值。展开更多
目的:研究MRI 3D CUBE T_(2)序列检查在踝关节外伤患者韧带损伤诊断中的价值。方法:选择2020年4月—2023年4月于白银市第一人民医院就诊的226例踝关节外伤拟行手术术前患者作为研究对象,按照不同检查方式将患者分为观察组(n=126)与对照...目的:研究MRI 3D CUBE T_(2)序列检查在踝关节外伤患者韧带损伤诊断中的价值。方法:选择2020年4月—2023年4月于白银市第一人民医院就诊的226例踝关节外伤拟行手术术前患者作为研究对象,按照不同检查方式将患者分为观察组(n=126)与对照组(n=100)。观察组采用MRI 3D CUBE T_(2)序列检查,对照组采取常规MRI检查。比较两组患侧、健侧距腓前韧带测量结果、诊断效能。结果:两组患侧、健侧距腓前韧带宽度及厚度比较,差异无统计学意义(P>0.05)。观察组Ⅰ级踝关节外伤患者韧带损伤诊断准确度、敏感度、特异度、阳性预测值、阴性预测值高于对照组,Ⅱ级患者准确度、敏感度、阴性预测值高于对照组,Ⅲ级患者准确度、特异度、阳性预测值高于对照组,差异有统计学意义(P<0.05)。结论:MRI 3D CUBE T_(2)序列检查踝关节外伤患者韧带损伤诊断效能高于常规MRI检查,可作为治疗效果评价及康复治疗的重要依据。展开更多
文摘Purpose: Commonly used diffusion weighted (DW) imaging such as DW spin echo (SE) type echo planar imaging (DW-SE-EPI) is known to be a snapshot-like acquisition and to have a relatively high signal-to-noise ratio. Spiral MRI sequence (SPIRAL) has characteristics similar to these of EPI, but it has rarely been used for diffusion-weighted imaging (DWI). In vivo DW-SPIRAL of the rat brain has almost never been reported. Our purpose in this study was to examine the potential of SE-type two-dimensional (2D) multi-shot spiral acquisition MRI for apparent diffusion coefficient (ADC) mapping of the rat brain in vivo. Materials and Methods: We made an SE-type DW-2D-spiral MRI sequence (DW-SPIRAL) which was prepared on a 2.0-T animal-experiment MR scanner. Comparing the phantom experimental result of DW-SPIRAL with the phantom experimental result of DW SE-type echo-planar imaging (DW-SE-EPI) and conventional DW spin echo imaging (DW-SE), we estimated the characteristics of DW-SPIRAL and assessed the clinical application of DW-SPIRAL in an animal experiment on the rat brain. Results: There was not much difference between the calculated water/glycerol phantom diffusion coefficient of DW-SPIRAL and the calculated diffusion coefficient of DW-SE. This result shows that the DW-SPIRAL sequence is appropriate for use in diffusion weighted imaging. There were fewer phantom image distortions and ghosting artifacts with DW-SPIRAL than with DW-SE-EPI, and this tendency was similar in the animal experiment on the rat brain. Conclusion: The DW-SPIRAL sequence had been successfully tested in phantom experiments and rat brain experiments. It has been demonstrated that the DW-SPIRAL sequence is capable of producing in vivo rat brain DWI.
文摘目的探讨MRI多序列成像在肝硬化背景下小肝癌诊断和微血管侵犯评估中的应用价值。方法选择2020年9月~2022年9月在我院接受诊断的80例疑似小肝癌的患者为研究对象,均采用西门子3.0 T Verio超导型磁共振扫描仪检查,分析MRI多序列成像对肝硬化背景下小肝癌诊断和微血管侵犯评估中的应用价值,以肝脏穿刺活检为金标准,采用Kappa一致性检验,分析MRI多序列成像在小肝癌诊断和微血管侵犯的一致性。结果80例疑似小肝癌患者经病理确诊36例,未发生肝癌44例。T2WI诊断敏感度为83.33%,特异度为79.55%,准确度为81.25%,Kappa值为0.624;T1WI诊断敏感度为77.78%,特异度为81.82%,准确度为80.00%,,Kappa值为0.596;LAVA诊断敏感度为83.33%,特异度为81.82%,准确度为82.50%,Kappa值为0.648;联合诊断敏感度为94.44%,特异度为77.27%,准确度为85.00%,Kappa值为0.703。36例疑似小肝癌患者经病理确诊MVI 7例,未发生MVI 29例。T2WI诊断敏感度为71.43%,特异度为86.21%,准确度为83.33%,Kappa值为0.520;T1WI诊断敏感度为71.43%,特异度为82.76%,准确度为80.56%,Kappa值为0.466;LAVA诊断敏感度为71.43%,特异度为89.66%,准确度为86.11%,Kappa值为0.579;联合诊断敏感度为85.71%,特异度为82.76%,准确度为83.33%,Kappa值为0.563。结论MRI多序列成像有助于提高肝硬化背景下小肝癌的诊断和微血管侵犯的评估,具有良好的应用价值。
文摘目的:研究MRI 3D CUBE T_(2)序列检查在踝关节外伤患者韧带损伤诊断中的价值。方法:选择2020年4月—2023年4月于白银市第一人民医院就诊的226例踝关节外伤拟行手术术前患者作为研究对象,按照不同检查方式将患者分为观察组(n=126)与对照组(n=100)。观察组采用MRI 3D CUBE T_(2)序列检查,对照组采取常规MRI检查。比较两组患侧、健侧距腓前韧带测量结果、诊断效能。结果:两组患侧、健侧距腓前韧带宽度及厚度比较,差异无统计学意义(P>0.05)。观察组Ⅰ级踝关节外伤患者韧带损伤诊断准确度、敏感度、特异度、阳性预测值、阴性预测值高于对照组,Ⅱ级患者准确度、敏感度、阴性预测值高于对照组,Ⅲ级患者准确度、特异度、阳性预测值高于对照组,差异有统计学意义(P<0.05)。结论:MRI 3D CUBE T_(2)序列检查踝关节外伤患者韧带损伤诊断效能高于常规MRI检查,可作为治疗效果评价及康复治疗的重要依据。
