AIM To identify risk factors for clinically relevant complications after spleen-preserving distal pancreatectomy(SPDP). No previous studies explored potential predictors of morbidity after SPDP.METHODS The data of 41 ...AIM To identify risk factors for clinically relevant complications after spleen-preserving distal pancreatectomy(SPDP). No previous studies explored potential predictors of morbidity after SPDP.METHODS The data of 41 patients who underwent a SPDP in a single surgical center between 2000 and 2015 were retrospectively reviewed from a prospectively maintained electronic database established in our Department of Surgery. The database included demographic, clinical, bioumoral, pathological, intraoperative and postoperative parameters. Uni-and multivariate ana-lyses were performed to assess potential predictors of clinically relevant morbidity. Postoperative morbidity was defined as in-hospital complications and mortality was assessed at 90 d. Clinically relevant morbidity was defined as complication ≥ grade 2 Dindo.RESULTS Overall morbidity rate was 34.1%(14 patients): grade Ⅰ(6 patients, 14.6%), grade Ⅱ(2 patients, 4.8%), grade Ⅲa(1 patient, 2.4%), and grade Ⅲb(5 patients, 12.2%). A number of 5 patients(12.2%) required re-laparotomy for postoperative complications. There was no postoperative mortality. Thus, at least one clinically relevant complication occurred in 8 patients(19.5%). Univariate analysis identified male gender(P = 0.034), increased body mass index(P = 0.002) and neuroendocrine pathology(P = 0.013) as statistically significant risk factors. Multivariate analysis identified male gender [odds ratio(OR): 1.29, 95%CI: 1.07-1.55, P = 0.005] and increased body mass index(OR: 23.18, 95%CI: 1.72-310.96, P = 0.018) as the only independent risk factors of clinically relevant morbidity after SPDP.CONCLUSION Male gender and increased body mass index are independently associated with increased risk of clinically relevant morbidity after SPDP. These findings may assist a surgeon in clinical decision-making to better select patients suitable for SPDP.展开更多
目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,...目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,每组50例。对照组采用IPL治疗,观察组采用清热除湿汤加减联合IPL治疗,均持续治疗4个月。评价患者疗效和治疗前后中医证候积分。分别于治疗前后采用玫瑰痤疮医师全球评分(Physician’s global assessment,PGA)对患者玫瑰痤疮情况进行评分;分别于治疗前、治疗后2个月和治疗后4个月,使用皮肤病生活质量指数量表(Dermatology life quality index,DLQI)评估患者生活质量。记录两组治疗期间的不良反应发生情况。结果:观察组治疗有效率为92.00%,明显高于对照组的76.00%,差异有统计学意义(P<0.05);治疗后,观察组中医证候积分明显低于对照组,观察组患者玫瑰痤疮改善程度明显优于对照组,生活质量明显高于对照组,差异均有统计学意义(P<0.05)。观察组患者治疗期间的不良反应发生率为10.00%,与对照组(14.00%)比较差异无统计学意义(P>0.05)。结论:清热除湿汤加减联合IPL治疗轻中度脾胃湿热型玫瑰痤疮可明显提高临床疗效,改善患者生活质量。展开更多
文摘AIM To identify risk factors for clinically relevant complications after spleen-preserving distal pancreatectomy(SPDP). No previous studies explored potential predictors of morbidity after SPDP.METHODS The data of 41 patients who underwent a SPDP in a single surgical center between 2000 and 2015 were retrospectively reviewed from a prospectively maintained electronic database established in our Department of Surgery. The database included demographic, clinical, bioumoral, pathological, intraoperative and postoperative parameters. Uni-and multivariate ana-lyses were performed to assess potential predictors of clinically relevant morbidity. Postoperative morbidity was defined as in-hospital complications and mortality was assessed at 90 d. Clinically relevant morbidity was defined as complication ≥ grade 2 Dindo.RESULTS Overall morbidity rate was 34.1%(14 patients): grade Ⅰ(6 patients, 14.6%), grade Ⅱ(2 patients, 4.8%), grade Ⅲa(1 patient, 2.4%), and grade Ⅲb(5 patients, 12.2%). A number of 5 patients(12.2%) required re-laparotomy for postoperative complications. There was no postoperative mortality. Thus, at least one clinically relevant complication occurred in 8 patients(19.5%). Univariate analysis identified male gender(P = 0.034), increased body mass index(P = 0.002) and neuroendocrine pathology(P = 0.013) as statistically significant risk factors. Multivariate analysis identified male gender [odds ratio(OR): 1.29, 95%CI: 1.07-1.55, P = 0.005] and increased body mass index(OR: 23.18, 95%CI: 1.72-310.96, P = 0.018) as the only independent risk factors of clinically relevant morbidity after SPDP.CONCLUSION Male gender and increased body mass index are independently associated with increased risk of clinically relevant morbidity after SPDP. These findings may assist a surgeon in clinical decision-making to better select patients suitable for SPDP.
文摘目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,每组50例。对照组采用IPL治疗,观察组采用清热除湿汤加减联合IPL治疗,均持续治疗4个月。评价患者疗效和治疗前后中医证候积分。分别于治疗前后采用玫瑰痤疮医师全球评分(Physician’s global assessment,PGA)对患者玫瑰痤疮情况进行评分;分别于治疗前、治疗后2个月和治疗后4个月,使用皮肤病生活质量指数量表(Dermatology life quality index,DLQI)评估患者生活质量。记录两组治疗期间的不良反应发生情况。结果:观察组治疗有效率为92.00%,明显高于对照组的76.00%,差异有统计学意义(P<0.05);治疗后,观察组中医证候积分明显低于对照组,观察组患者玫瑰痤疮改善程度明显优于对照组,生活质量明显高于对照组,差异均有统计学意义(P<0.05)。观察组患者治疗期间的不良反应发生率为10.00%,与对照组(14.00%)比较差异无统计学意义(P>0.05)。结论:清热除湿汤加减联合IPL治疗轻中度脾胃湿热型玫瑰痤疮可明显提高临床疗效,改善患者生活质量。
