Perioperative restricted fluid therapy preserves immunological function in patients with colorectal cancer

AIM:To investigate the effect of perioperative restricted fluid therapy on circulating CD4+/CD8+T lymphocyte ratio,percentage of regulatory T cells(Treg)and postoperative complications in patients with colorectal cancer.METHODS:A total of 185 patients met the inclusion criteria and were included in the randomized clinical trial.These patients were divided into two groups according to receipt of either perioperative standard(S,n=89)or restricted(R,n=96)fluid therapy.Clinical data of these patients were collected in this prospective study.Perioperative complications and cellular immunity changes(CD4+/CD8+and Treg)were analyzed comparatively between the two groups.RESULTS:Both during surgery and on postoperativedays,the total volumes of fluids administered in the R group were significantly lower than those in the S group(1620±430 mL vs 3110±840 mL;2090±360mL vs 2750±570 mL;1750±260 mL vs 2740±490mL;1620±310 mL vs 2520±300 mL;P<0.05).Decreased ratios of circulating CD4+/CD8+T lymphocytes(1.47±0.28 vs 2.13±0.26;1.39±0.32 vs 2.21±0.24;P<0.05)and Treg percentage values(2.79±1.24vs 4.26±1.04;2.46±0.98 vs 4.30±1.12;P<0.05)were observed after surgery in both groups.However,in the R group,these values restored more quickly starting from postoperative day 2(1.44±0.24 vs 1.34±0.27;2.93±1.08 vs 2.52±0.96;P<0.05).The proportion of patients with complications was significantly lower in the restricted group(36 of 89 vs 59 of 96,P<0.01).CONCLUSION:Perioperative restricted intravenous fluid regimen leads to a low postoperative complication rate and better cellular immunity preservation in patients with colorectal cancer.

Brand Marketing Strategies in the Export of Maoming Litchi

The thesis gives the brief overview of the development of Maoming litchi industry:it has the largest scale base and the output keeps going up;it has varieties of species and lots of famous special products;its standardized mass production ensures the safety of the products;the products go to market early with a broad range of sales;it has industrialized fruit production and deep product processing technology. After an introduction to the general situation of the export of litchis in China,the thesis introduces the current situation of the export of litchis in Maoming in terms of the continuously increasing exportations and the continuous expansion of the market and then,based on these,the thesis analyzes the existing problems in the export of Maoming Litchi:first,lack of brand awareness results in products with no brand;second,the instability of quality acts as a drawback to the exportation;third,fresh litchis are the main exportations,and the packaging and transportation technology of products are weak and thus the overseas markets are by no means well-explored. In order to adapt to the accelerating economic globalization,seize new opportunities for economic development,promote litchi exports from sluggish to healthy development and thus come to the successful transition of Maoming City as an agricultural city to a strong city in agricultural science and technology,corresponding strategies of the brand marketing of Maoming Litchi are put forward in the thesis:first,to enhance brand awareness and make it a famous brand;second,to build bases for litchis' export and make Chinese litchis known worldwide;third,to pay intensive attention to the preservation of litchis and propel industrial management;fourth,to improve the market distribution system and open up the international market.

参会代表系列专访（英文）

Standarization plays an importat driving role in the scientific and technoLogical development. This is well reflected in the development of scientific research and engineering technology research and the improvement of products quality from backward level to high, internationally advaneed or even internationally leading level.