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PEMFC Identification Based on a Fractional-Order Hammerstein State-Space Model with ADE-BH Optimization
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作者 Qin Hao Qi Zhidong +1 位作者 Ye Weiqin Sun Chengshuo 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS CSCD 2023年第2期155-164,共10页
Considering the fractional-order and nonlinear characteristics of proton exchange membrane fuel cells(PEMFC),a fractional-order subspace identification method based on the ADE-BH optimization algorithm is proposed to ... Considering the fractional-order and nonlinear characteristics of proton exchange membrane fuel cells(PEMFC),a fractional-order subspace identification method based on the ADE-BH optimization algorithm is proposed to establish a fractional-order Hammerstein state-space model of PEMFCs.Herein,a Hammerstein model is constructed by connecting a linear module and a nonlinear module in series to precisely depict the nonlinear property of the PEMFC.During the modeling process,fractional-order theory is combined with subspace identification,and a Poisson filter is adopted to enable multi-order derivability of the data.A variable memory method is introduced to reduce computation time without losing precision.Additionally,to improve the optimization accuracy and avoid obtaining locally optimum solutions,a novel ADEBH algorithm is employed to optimize the unknown parameters in the identification method.In this algorithm,the Euclidean distance serves as the theoretical basis for updating the target vector in the absorption-generation operation of the black hole(BH)algorithm.Finally,simulations demonstrate that the proposed model has small output error and high accuracy,indicating that the model can accurately describe the electrical characteristics of the PEMFC process. 展开更多
关键词 PEMFC Hammerstein model Fractional subspace identification ADE-BH optimization
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An Improved Time Domain Approach for Analysis of Floating Bridges Based on Dynamic Finite Element Method and State-Space Model
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作者 XIANG Sheng CHENG Bin +1 位作者 ZHANG Feng-yu TANG Miao 《China Ocean Engineering》 SCIE EI CSCD 2022年第5期682-696,共15页
The floating bridge bears the dead weight and live load with buoyancy,and has wide application prospect in deep-water transportation infrastructure.The structural analysis of floating bridge is challenging due to the ... The floating bridge bears the dead weight and live load with buoyancy,and has wide application prospect in deep-water transportation infrastructure.The structural analysis of floating bridge is challenging due to the complicated fluid-solid coupling effects of wind and wave.In this research,a novel time domain approach combining dynamic finite element method and state-space model(SSM)is established for the refined analysis of floating bridges.The dynamic coupled effects induced by wave excitation load,radiation load and buffeting load are carefully simulated.High-precision fitted SSMs for pontoons are established to enhance the calculation efficiency of hydrodynamic radiation forces in time domain.The dispersion relation is also introduced in the analysis model to appropriately consider the phase differences of wave loads on pontoons.The proposed approach is then employed to simulate the dynamic responses of a scaled floating bridge model which has been tested under real wind and wave loads in laboratory.The numerical results are found to agree well with the test data regarding the structural responses of floating bridge under the considered environmental conditions.The proposed time domain approach is considered to be accurate and effective in simulating the structural behaviors of floating bridge under typical environmental conditions. 展开更多
关键词 floating bridge time domain analysis dynamic analysis state-space model environmental load
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A Study on the Factors Influencing the Income Gap between Urban and Rural Areas Based on State-space Model 被引量:2
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作者 Xiaofang ZOU Xueqin JIANG 《Asian Agricultural Research》 2014年第9期1-6,共6页
The increasingly widening income gap between urban and rural areas is affected by many factors. Using the stepwise regression analysis,we find that urbanization level,socio-economic development,education level,financi... The increasingly widening income gap between urban and rural areas is affected by many factors. Using the stepwise regression analysis,we find that urbanization level,socio-economic development,education level,financial development scale and financial development efficiency have the greatest impact on the income gap between urban and rural areas. By cointegration test,it is found that there is a long-term equilibrium relationship between these five variables and the income gap between urban and rural areas. We build the state-space model to research the dynamic impact of these factors on the income gap between urban and rural areas. The results show that by improving the level of urbanization,we can effectively narrow the income gap between urban and rural areas,while socio-economic development,the improvement of education level,expansion of financial development scale and financial development efficiency all significantly expand the income gap between urban and rural areas. 展开更多
关键词 INCOME GAP BETWEEN URBAN and RURAL areas State-spa
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Least Squares Matrix Algorithm for State-Space Modelling of Dynamic Systems
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作者 Juuso T. Olkkonen Hannu Olkkonen 《Journal of Signal and Information Processing》 2011年第4期287-291,共5页
This work presents a novel least squares matrix algorithm (LSM) for the analysis of rapidly changing systems using state-space modelling. The LSM algorithm is based on the Hankel structured data matrix representation.... This work presents a novel least squares matrix algorithm (LSM) for the analysis of rapidly changing systems using state-space modelling. The LSM algorithm is based on the Hankel structured data matrix representation. The state transition matrix is updated without the use of any forgetting function. This yields a robust estimation of model parameters in the presence of noise. The computational complexity of the LSM algorithm is comparable to the speed of the conventional recursive least squares (RLS) algorithm. The knowledge of the state transition matrix enables feasible numerical operators such as interpolation, fractional differentiation and integration. The usefulness of the LSM algorithm was proved in the analysis of the neuroelectric signal waveforms. 展开更多
关键词 state-space modelLING DYNAMIC SYSTEM Analysis EEG
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Harmonic State-Space Based AC-Side Impedance Model of MMC and High Frequency Oscillation Characteristics Analysis
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作者 Hui Fang Jingsen Zhou +3 位作者 Haozheng Wang Yanxu Wang Hongji Xiang Yechun Xin 《Energy Engineering》 EI 2023年第4期831-849,共19页
Recently,high-frequency oscillation of themodularmultilevel converter(MMC)based high-voltage direct current(HVDC)projects has attracted great attentions.In order to analyze the small-signal stability,this paper uses t... Recently,high-frequency oscillation of themodularmultilevel converter(MMC)based high-voltage direct current(HVDC)projects has attracted great attentions.In order to analyze the small-signal stability,this paper uses the harmonic state-space(HSS)method to establish a detailed frequency domain impedance model of the AC-side of the HVDC transmission system,which considers the internal dynamic characteristics.In addition,the suggested model is also used to assess the system’s high-frequency oscillationmechanism,and the effects of the MMC current inner loop control,feedforward voltage links,and control delay on the high-frequency impedance characteristics and the effect of higher harmonic components.Finally,three oscillation suppression schemes are analyzed for the oscillation problems occurring in actual engineering,and a simplified impedance model considering only the highfrequency impedance characteristics is established to compare the suppression effect with the detailed impedance model to prove its reliability. 展开更多
关键词 Modular multilevel converter impedance modeling small-signal stability suppression strategy
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Tracking of time-evolving sound speed profiles with an auto-regressive state-space model 被引量:4
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作者 JIN Liling LI Jianlong XU Wen 《Chinese Journal of Acoustics》 CSCD 2017年第3期302-312,共11页
An approach for time-evolving sound speed profiles tracking in shallow water is discussed. The inversion of time-evolving sound speed profiles is modeled as a state-space estimation problem, which includes a state equ... An approach for time-evolving sound speed profiles tracking in shallow water is discussed. The inversion of time-evolving sound speed profiles is modeled as a state-space estimation problem, which includes a state equation for predicting the time-evolving sound speed profile and a measurement equation for incorporating local acoustic measurements. In the paper, auto-regression (AR) method is introduced to obtain a high-order AR evolution model of the sound speed field time variations, and the ensemble Kalman filter is utilized to track the sound speed field. To validate the approach, the accuracy in sound speed estimation is analyzed via a numerical implementation using the ASIAEX experimental environment and the sound velocity measurement data. Compared with traditional approaches based on the state evolution represented as a random walk, simulation results show the proposed AR method can effectively reduce the tracking errors of sound speed, and still keep good tracking performance at low signal-to-noise ratios. 展开更多
关键词 TIME Tracking of time-evolving sound speed profiles with an auto-regressive state-space model SSP ENKF AR
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STATE-SPACE MODELLING OF DYNAMIC SYSTEMS IN OCEAN ENGINEERING 被引量:2
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作者 JohannesFalnes 《Journal of Hydrodynamics》 SCIE EI CSCD 1998年第1期1-17,共17页
Pertaining to dynamic systems in general, a review is given of relations between mathematical descriptions in the frequency domain or time domain and state-space descriptions. For the analysis of hydrodynamic problems... Pertaining to dynamic systems in general, a review is given of relations between mathematical descriptions in the frequency domain or time domain and state-space descriptions. For the analysis of hydrodynamic problems in ocean engineering wave forces may be represented by convolution integrals. The paper presents a method to construct a finite-order state-space model which represents a good approximation to such a convolution integral. The method utilizes a particular algorithm to compute the partial derivative of the exponential function of a (state-space) matrix with respect to the matrix elements. The method is applied to an example of fitting a state space model of order five to the free oscillations corresponding to wave radiation in a transient experiment with an oscillating water column. 展开更多
关键词 wave forces SIMULATION state-space model least-square method oscillating water column heave motion
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基于24Model-D-ISM的地铁站火灾疏散影响因素研究
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作者 孙世梅 张家严 《中国安全科学学报》 CAS CSCD 北大核心 2024年第4期153-159,共7页
为预防地铁站火灾事故,深入了解地铁站火灾人员疏散影响因素间的内在联系与层次结构,基于第6版“2-4”模型(24Model)分析63起地铁站火灾疏散事故,充分考虑各个因素之间的交互作用,提取19个影响地铁站人员疏散的关键因素,建立地铁站火灾... 为预防地铁站火灾事故,深入了解地铁站火灾人员疏散影响因素间的内在联系与层次结构,基于第6版“2-4”模型(24Model)分析63起地铁站火灾疏散事故,充分考虑各个因素之间的交互作用,提取19个影响地铁站人员疏散的关键因素,建立地铁站火灾人员疏散影响因素指标体系;采用算子客观赋权法(C-OWA)改进决策试验与评价实验法(DEMATEL),确定地铁站火灾人员疏散的重要影响因素;在此基础上,采用解释结构模型(ISM)分析各个因素间的层次结构及相互作用路径,构建地铁站火灾人员疏散影响因素的多级递阶结构模型。研究结果表明:疏散引导、恐慌从众行为、人员拥挤为地铁站火灾人员疏散的关键影响因素;地铁站火灾人员疏散受表层因素、中间层因素、深层因素共同作用的影响,其中,疏散教育与培训、设施维护与检查、疏散预案等因素是根源影响因素,重视根源影响因素的改善有利于从本质上预防和控制事故的发生。 展开更多
关键词 “2-4”模型(24model) 决策试验与评价实验法(DEMATEL) 解释结构模型(ISM) 地铁站 火灾疏散 影响因素
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Identification of the state-space model and payload mass parameter of a flexible space manipulator using a recursive subspace tracking method 被引量:9
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作者 Zhiyu NI Jinguo LIU +1 位作者 Zhigang WU Xinhui SHEN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2019年第2期513-530,共18页
The on-orbit parameter identification of a space structure can be used for the modification of a system dynamics model and controller coefficients. This study focuses on the estimation of a system state-space model fo... The on-orbit parameter identification of a space structure can be used for the modification of a system dynamics model and controller coefficients. This study focuses on the estimation of a system state-space model for a two-link space manipulator in the procedure of capturing an unknown object, and a recursive tracking approach based on the recursive predictor-based subspace identification(RPBSID) algorithm is proposed to identify the manipulator payload mass parameter. Structural rigid motion and elastic vibration are separated, and the dynamics model of the space manipulator is linearized at an arbitrary working point(i.e., a certain manipulator configuration).The state-space model is determined by using the RPBSID algorithm and matrix transformation. In addition, utilizing the identified system state-space model, the manipulator payload mass parameter is estimated by extracting the corresponding block matrix. In numerical simulations, the presented parameter identification method is implemented and compared with the classical algebraic algorithm and the recursive least squares method for different payload masses and manipulator configurations. Numerical results illustrate that the system state-space model and payload mass parameter of the two-link flexible space manipulator are effectively identified by the recursive subspace tracking method. 展开更多
关键词 Flexible space manipulator LINEARIZATION PARAMETER IDENTIFICATION state-space model SUBSPACE methods
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耦合优化蚁群算法与P-Median model的选址模型设计
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作者 顾梓程 胡新玲 《现代电子技术》 北大核心 2024年第3期109-114,共6页
为节省城建部门对于公共体育设施的投入成本以及提高城市人民生活质量,以运动场所优化选址为例,提出一种新型设施选址模型。该模型主要基于P-Median model(最小化阻抗模型)根据需求点数量从全部候选设施选址中选择设施空间位置,让用户... 为节省城建部门对于公共体育设施的投入成本以及提高城市人民生活质量,以运动场所优化选址为例,提出一种新型设施选址模型。该模型主要基于P-Median model(最小化阻抗模型)根据需求点数量从全部候选设施选址中选择设施空间位置,让用户达到离自己最近设施距离成本总和最小的目的,对选址的基本原则和实际情况提出要求,构造目标函数用于优化后蚁群算法求解进行选址工作。优化蚁群算法实现基于Python语言模块,通过改进蚁群原始信息素,提升原有算法的收敛速度,求出目标函数最优解,可以很好地模拟对于运动场所的选址。用二者耦合进行优势互补所设计的选址模型来搜寻研究区蚁群信息素浓度残留最大的栅格像元,从而确定未被已有设施点服务半径覆盖的最佳设施点建立位置。实验结果表明,该新型选址模型相较于最小化阻抗模型与最大化覆盖模型,新增优化设施点使整体服务半径覆盖率分别高出10.42%和6.95%,适合求解较为精确且小规模空间下的选址问题。 展开更多
关键词 蚁群算法 P-Median model 选址模型 GIS 运动场所 位置分配 PYTHON
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Mshpy23:a user-friendly,parameterized model of magnetosheath conditions 被引量:1
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作者 Jaewoong Jung Hyunju Connor +3 位作者 Andrew Dimmock Steve Sembay Andrew Read Jan Soucek 《Earth and Planetary Physics》 EI CSCD 2024年第1期89-104,共16页
Lunar Environment heliospheric X-ray Imager(LEXI)and Solar wind−Magnetosphere−Ionosphere Link Explorer(SMILE)will observe magnetosheath and its boundary motion in soft X-rays for understanding magnetopause reconnectio... Lunar Environment heliospheric X-ray Imager(LEXI)and Solar wind−Magnetosphere−Ionosphere Link Explorer(SMILE)will observe magnetosheath and its boundary motion in soft X-rays for understanding magnetopause reconnection modes under various solar wind conditions after their respective launches in 2024 and 2025.Magnetosheath conditions,namely,plasma density,velocity,and temperature,are key parameters for predicting and analyzing soft X-ray images from the LEXI and SMILE missions.We developed a userfriendly model of magnetosheath that parameterizes number density,velocity,temperature,and magnetic field by utilizing the global Magnetohydrodynamics(MHD)model as well as the pre-existing gas-dynamic and analytic models.Using this parameterized magnetosheath model,scientists can easily reconstruct expected soft X-ray images and utilize them for analysis of observed images of LEXI and SMILE without simulating the complicated global magnetosphere models.First,we created an MHD-based magnetosheath model by running a total of 14 OpenGGCM global MHD simulations under 7 solar wind densities(1,5,10,15,20,25,and 30 cm)and 2 interplanetary magnetic field Bz components(±4 nT),and then parameterizing the results in new magnetosheath conditions.We compared the magnetosheath model result with THEMIS statistical data and it showed good agreement with a weighted Pearson correlation coefficient greater than 0.77,especially for plasma density and plasma velocity.Second,we compiled a suite of magnetosheath models incorporating previous magnetosheath models(gas-dynamic,analytic),and did two case studies to test the performance.The MHD-based model was comparable to or better than the previous models while providing self-consistency among the magnetosheath parameters.Third,we constructed a tool to calculate a soft X-ray image from any given vantage point,which can support the planning and data analysis of the aforementioned LEXI and SMILE missions.A release of the code has been uploaded to a Github repository. 展开更多
关键词 MAGNETOSHEATH PYTHON modelING
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24Model与LCM原因因素定义对比研究
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作者 袁晨辉 傅贵 +1 位作者 吴治蓉 赵金坤 《中国安全科学学报》 CAS CSCD 北大核心 2024年第1期27-34,共8页
为探究损失致因模型(LCM)原因因素定义与事故致因“2-4”模型(24Model)存在的异同和优缺点,梳理2个模型各层面原因和结果的定义,对比定义内容及其对事故原因分析等安全实务的指导作用,并以一起瓦斯爆炸事故为例加以实证分析,获得二者分... 为探究损失致因模型(LCM)原因因素定义与事故致因“2-4”模型(24Model)存在的异同和优缺点,梳理2个模型各层面原因和结果的定义,对比定义内容及其对事故原因分析等安全实务的指导作用,并以一起瓦斯爆炸事故为例加以实证分析,获得二者分析结果之间的差异。研究结果表明:LCM是首个将管理因素纳入事故致因分析的一维事件序列模型,可明确各层面原因因素的定义和因素间的逻辑关系,但部分定义存在交叉重复的问题,并没有揭示安全工作指导思想等深层次事故致因因素;24Model作为系统性事故致因模型,对各类因素的定义均以组织为主体,描述事件、事故、安全的概念内涵,划分个体安全动作、安全能力和组织安全管理体系的类别并给出含义解析,探究组织安全文化层面的问题并以32个元素体现;2个模型的事故原因分析方法均建立在对各层级原因因素定义的基础上,并适用于模型理论体系本身。 展开更多
关键词 “2-4”模型(24model) 损失致因模型(LCM) 事故致因模型 原因因素定义 对比研究
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Assessing the Performance of CMIP6 Models in Simulating Droughts across Global Drylands 被引量:1
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作者 Xiaojing YU Lixia ZHANG +1 位作者 Tianjun ZHOU Jianghua ZHENG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第2期193-208,共16页
Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the curr... Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the current state-of-the-art Coupled Model Intercomparison Project phase 6(CMIP6) models remain unknown. Here, both the strengths and weaknesses of CMIP6 models in simulating droughts and corresponding hydrothermal conditions in drylands are assessed.While the general patterns of simulated meteorological elements in drylands resemble the observations, the annual precipitation is overestimated by ~33%(with a model spread of 2.3%–77.2%), along with an underestimation of potential evapotranspiration(PET) by ~32%(17.5%–47.2%). The water deficit condition, measured by the difference between precipitation and PET, is 50%(29.1%–71.7%) weaker than observations. The CMIP6 models show weaknesses in capturing the climate mean drought characteristics in drylands, particularly with the occurrence and duration largely underestimated in the hyperarid Afro-Asian areas. Nonetheless, the drought-associated meteorological anomalies, including reduced precipitation, warmer temperatures, higher evaporative demand, and increased water deficit conditions, are reasonably reproduced. The simulated magnitude of precipitation(water deficit) associated with dryland droughts is overestimated by 28%(24%) compared to observations. The observed increasing trends in drought fractional area,occurrence, and corresponding meteorological anomalies during 1980–2014 are reasonably reproduced. Still, the increase in drought characteristics, associated precipitation and water deficit are obviously underestimated after the late 1990s,especially for mild and moderate droughts, indicative of a weaker response of dryland drought changes to global warming in CMIP6 models. Our results suggest that it is imperative to employ bias correction approaches in drought-related studies over drylands by using CMIP6 outputs. 展开更多
关键词 DROUGHTS hydrothermal conditions DRYLANDS CMIP6 model evaluation
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Genetically modified non-human primate models for research on neurodegenerative diseases 被引量:1
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作者 Ming-Tian Pan Han Zhang +1 位作者 Xiao-Jiang Li Xiang-Yu Guo 《Zoological Research》 SCIE CSCD 2024年第2期263-274,共12页
Neurodegenerative diseases(NDs)are a group of debilitating neurological disorders that primarily affect elderly populations and include Alzheimer's disease(AD),Parkinson's disease(PD),Huntington's disease(... Neurodegenerative diseases(NDs)are a group of debilitating neurological disorders that primarily affect elderly populations and include Alzheimer's disease(AD),Parkinson's disease(PD),Huntington's disease(HD),and amyotrophic lateral sclerosis(ALS).Currently,there are no therapies available that can delay,stop,or reverse the pathological progression of NDs in clinical settings.As the population ages,NDs are imposing a huge burden on public health systems and affected families.Animal models are important tools for preclinical investigations to understand disease pathogenesis and test potential treatments.While numerous rodent models of NDs have been developed to enhance our understanding of disease mechanisms,the limited success of translating findings from animal models to clinical practice suggests that there is still a need to bridge this translation gap.Old World nonhuman primates(NHPs),such as rhesus,cynomolgus,and vervet monkeys,are phylogenetically,physiologically,biochemically,and behaviorally most relevant to humans.This is particularly evident in the similarity of the structure and function of their central nervous systems,rendering such species uniquely valuable for neuroscience research.Recently,the development of several genetically modified NHP models of NDs has successfully recapitulated key pathologies and revealed novel mechanisms.This review focuses on the efficacy of NHPs in modeling NDs and the novel pathological insights gained,as well as the challenges associated with the generation of such models and the complexities involved in their subsequent analysis. 展开更多
关键词 NEURODEGENERATION Non-human primate Macaque monkey Animal model Gene modification
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Large animal models for Huntington's disease research 被引量:1
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作者 Bofeng Han Weien Liang +3 位作者 Xiao-Jiang Li Shihua Li Sen Yan Zhuchi Tu 《Zoological Research》 SCIE CSCD 2024年第2期275-283,共9页
Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no effectivetreatmentavailable.Consequently,the development of appropriate disease models is critical to thoroughly inve... Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no effectivetreatmentavailable.Consequently,the development of appropriate disease models is critical to thoroughly investigate disease progression.The genetic basis of HD involves the abnormal expansion of CAG repeats in the huntingtin(HTT)gene,leading to the expansion of a polyglutamine repeat in the HTT protein.Mutant HTT carrying the expanded polyglutamine repeat undergoes misfolding and forms aggregates in the brain,which precipitate selective neuronal loss in specific brain regions.Animal models play an important role in elucidating the pathogenesis of neurodegenerative disorders such as HD and in identifying potential therapeutic targets.Due to the marked species differences between rodents and larger animals,substantial efforts have been directed toward establishing large animal models for HD research.These models are pivotal for advancing the discovery of novel therapeutic targets,enhancing effective drug delivery methods,and improving treatment outcomes.We have explored the advantages of utilizing large animal models,particularly pigs,in previous reviews.Since then,however,significant progress has been made in developing more sophisticated animal models that faithfully replicate the typical pathology of HD.In the current review,we provide a comprehensive overview of large animal models of HD,incorporating recent findings regarding the establishment of HD knock-in(KI)pigs and their genetic therapy.We also explore the utilization of large animal models in HD research,with a focus on sheep,non-human primates(NHPs),and pigs.Our objective is to provide valuable insights into the application of these large animal models for the investigation and treatment of neurodegenerative disorders. 展开更多
关键词 Huntington's disease Large animal models SHEEP Non-human primates Transgenic pigs
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Genetically modified pigs:Emerging animal models for hereditary hearing loss 被引量:1
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作者 Xiao Wang Tian-Xia Liu +7 位作者 Ying Zhang Liang-Wei Xu Shuo-Long Yuan A-Long Cui Wei-Wei Guo Yan-Fang Wang Shi-Ming Yang Jian-Guo Zhao 《Zoological Research》 SCIE CSCD 2024年第2期284-291,共8页
Hereditary hearing loss(HHL),a genetic disorder that impairs auditory function,significantly affects quality of life and incurs substantial economic losses for society.To investigate the underlying causes of HHL and e... Hereditary hearing loss(HHL),a genetic disorder that impairs auditory function,significantly affects quality of life and incurs substantial economic losses for society.To investigate the underlying causes of HHL and evaluate therapeutic outcomes,appropriate animal models are necessary.Pigs have been extensively used as valuable large animal models in biomedical research.In this review,we highlight the advantages of pig models in terms of ear anatomy,inner ear morphology,and electrophysiological characteristics,as well as recent advancements in the development of distinct genetically modified porcine models of hearing loss.Additionally,we discuss the prospects,challenges,and recommendations regarding the use pig models in HHL research.Overall,this review provides insights and perspectives for future studies on HHL using porcine models. 展开更多
关键词 PIGS Animal models Hereditary hearing loss Genetic modification Inner ear
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Kernel-Based State-Space Kriging for Predictive Control
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作者 A.Daniel Carnerero Daniel R.Ramirez +1 位作者 Daniel Limon Teodoro Alamo 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第5期1263-1275,共13页
In this paper, we extend the state-space kriging(SSK) modeling technique presented in a previous work by the authors in order to consider non-autonomous systems. SSK is a data-driven method that computes predictions a... In this paper, we extend the state-space kriging(SSK) modeling technique presented in a previous work by the authors in order to consider non-autonomous systems. SSK is a data-driven method that computes predictions as linear combinations of past outputs. To model the nonlinear dynamics of the system, we propose the kernel-based state-space kriging(K-SSK), a new version of the SSK where kernel functions are used instead of resorting to considerations about the locality of the data. Also, a Kalman filter can be used to improve the predictions at each time step in the case of noisy measurements. A constrained tracking nonlinear model predictive control(NMPC) scheme using the black-box input-output model obtained by means of the K-SSK prediction method is proposed. Finally, a simulation example and a real experiment are provided in order to assess the performance of the proposed controller. 展开更多
关键词 Data-driven methods model identification Kernel methods predictive control
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Genome-edited rabbits:Unleashing the potential of a promising experimental animal model across diverse diseases 被引量:1
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作者 Yang Han Jiale Zhou +3 位作者 Renquan Zhang Yuru Liang Liangxue Lai Zhanjun Li 《Zoological Research》 SCIE CSCD 2024年第2期253-262,共10页
Animal models are extensively used in all aspects of biomedical research,with substantial contributions to our understanding of diseases,the development of pharmaceuticals,and the exploration of gene functions.The fie... Animal models are extensively used in all aspects of biomedical research,with substantial contributions to our understanding of diseases,the development of pharmaceuticals,and the exploration of gene functions.The field of genome modification in rabbits has progressed slowly.However,recent advancements,particularly in CRISPR/Cas9-related technologies,have catalyzed the successful development of various genome-edited rabbit models to mimic diverse diseases,including cardiovascular disorders,immunodeficiencies,agingrelated ailments,neurological diseases,and ophthalmic pathologies.These models hold great promise in advancing biomedical research due to their closer physiological and biochemical resemblance to humans compared to mice.This review aims to summarize the novel gene-editing approaches currently available for rabbits and present the applications and prospects of such models in biomedicine,underscoring their impact and future potential in translational medicine. 展开更多
关键词 Genome editing Animal model RABBIT CRISPR/Cas9 Genetic diseases
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Background removal from global auroral images:Data-driven dayglow modeling 被引量:1
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作者 A.Ohma M.Madelaire +4 位作者 K.M.Laundal J.P.Reistad S.M.Hatch S.Gasparini S.J.Walker 《Earth and Planetary Physics》 EI CSCD 2024年第1期247-257,共11页
Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment.However,the cameras are sensitive not only to auroral emissions produced by precipitating particles,but... Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment.However,the cameras are sensitive not only to auroral emissions produced by precipitating particles,but also to dayglow emissions produced by photoelectrons induced by sunlight.Nightglow emissions and scattered sunlight can contribute to the background signal.To fully utilize such images in space science,background contamination must be removed to isolate the auroral signal.Here we outline a data-driven approach to modeling the background intensity in multiple images by formulating linear inverse problems based on B-splines and spherical harmonics.The approach is robust,flexible,and iteratively deselects outliers,such as auroral emissions.The final model is smooth across the terminator and accounts for slow temporal variations and large-scale asymmetries in the dayglow.We demonstrate the model by using the three far ultraviolet cameras on the Imager for Magnetopause-to-Aurora Global Exploration(IMAGE)mission.The method can be applied to historical missions and is relevant for upcoming missions,such as the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission. 展开更多
关键词 AURORA dayglow modeling global auroral images far ultraviolet images dayglow removal
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Fractal Fractional Order Operators in Computational Techniques for Mathematical Models in Epidemiology 被引量:1
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作者 Muhammad Farman Ali Akgül +2 位作者 Mir Sajjad Hashemi Liliana Guran Amelia Bucur 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1385-1403,共19页
New fractional operators, the COVID-19 model has been studied in this paper. By using different numericaltechniques and the time fractional parameters, the mechanical characteristics of the fractional order model arei... New fractional operators, the COVID-19 model has been studied in this paper. By using different numericaltechniques and the time fractional parameters, the mechanical characteristics of the fractional order model areidentified. The uniqueness and existence have been established. Themodel’sUlam-Hyers stability analysis has beenfound. In order to justify the theoretical results, numerical simulations are carried out for the presented methodin the range of fractional order to show the implications of fractional and fractal orders.We applied very effectivenumerical techniques to obtain the solutions of themodel and simulations. Also, we present conditions of existencefor a solution to the proposed epidemicmodel and to calculate the reproduction number in certain state conditionsof the analyzed dynamic system. COVID-19 fractional order model for the case of Wuhan, China, is offered foranalysis with simulations in order to determine the possible efficacy of Coronavirus disease transmission in theCommunity. For this reason, we employed the COVID-19 fractal fractional derivative model in the example ofWuhan, China, with the given beginning conditions. In conclusion, again the mathematical models with fractionaloperators can facilitate the improvement of decision-making for measures to be taken in the management of anepidemic situation. 展开更多
关键词 COVID-19 model fractal-fractional operator Ulam-Hyers stability existence and uniqueness numerical simulation
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