A class of stationary models of singular stochastic control has been studied, in which the state is extended to solution of a class of S.D.E. from Wiener process. The existence of optimal control has been proved in al...A class of stationary models of singular stochastic control has been studied, in which the state is extended to solution of a class of S.D.E. from Wiener process. The existence of optimal control has been proved in all cases under some weaker conditions, and the structure of optimal control may be characterized.展开更多
To ensure the safety of buildings surrounding foundation pits, a study was made on a settlement monitoring and trend prediction method. A statistical testing method for analyzing the stability of a settlement monitori...To ensure the safety of buildings surrounding foundation pits, a study was made on a settlement monitoring and trend prediction method. A statistical testing method for analyzing the stability of a settlement monitoring datum has been discussed. According to a comprehensive survey, data of 16 stages at operating control point, were verified by a standard t test to determine the stability of the operating control point. A stationary auto-regression model, AR(p), used for the observation point settlement prediction has been investigated. Given the 16 stages of the settlement data at an observation point, the applicability of this model was analyzed. Settlement of last four stages was predicted using the stationary auto-regression model AR (1); the maximum difference between predicted and measured values was 0.6 mm, indicating good prediction results of the model. Hence, this model can be applied to settlement predictions for buildings surrounding foundation pits.展开更多
Different fused-core stationary phase chemistries（C18,Amide,Phenyl-hexyl and Peptide ES-C18） were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase co...Different fused-core stationary phase chemistries（C18,Amide,Phenyl-hexyl and Peptide ES-C18） were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition（ACN or MeOH as organic modifier;formic acid or acetic acid,as acidifying component） on the column selectivity,peak shape and overall chromatographic performance were evaluated.The RP-amide column,combined with a formic acid-acetonitrile based gradient system,performed as best.A peptide reversed-phase retention model is proposed,consisting of 5 variables：log SumAA,log Sv,clog P,log nHDon and log nHAcc.Quantitative structure-retention relationship（QSRR） models were constructed for 16 different chromatographic systems.The accuracy of this peptide retention model was demonstrated by the comparison between predicted and experimentally obtained retention times,explaining on average 86% of the variability.Moreover,using an external set of 5 validation peptides,the predictive power of the model was also demonstrated.This peptide retention model includes the novel in-silico calculated amino acid descriptor,AA,which was calculated from log P,3D-MoRSE,RDF and WHIM descriptors.展开更多
基金Supported by the National Science Foundation of China.
文摘A class of stationary models of singular stochastic control has been studied, in which the state is extended to solution of a class of S.D.E. from Wiener process. The existence of optimal control has been proved in all cases under some weaker conditions, and the structure of optimal control may be characterized.
基金Project 50279005 supported by the National Natural Science Foundation of China
文摘To ensure the safety of buildings surrounding foundation pits, a study was made on a settlement monitoring and trend prediction method. A statistical testing method for analyzing the stability of a settlement monitoring datum has been discussed. According to a comprehensive survey, data of 16 stages at operating control point, were verified by a standard t test to determine the stability of the operating control point. A stationary auto-regression model, AR(p), used for the observation point settlement prediction has been investigated. Given the 16 stages of the settlement data at an observation point, the applicability of this model was analyzed. Settlement of last four stages was predicted using the stationary auto-regression model AR (1); the maximum difference between predicted and measured values was 0.6 mm, indicating good prediction results of the model. Hence, this model can be applied to settlement predictions for buildings surrounding foundation pits.
基金funded by a Ph.D.grant of "Institute for the Promotion of Innovation through Science and Technology in Flanders(IWT-Vlaanderen)"(No.091241 for MD and 073402 for SVD)the Special Research Fund of the Ghent University (Grant no.BOF 01J22510 for EW and BOF 01D38811 for SS)
文摘Different fused-core stationary phase chemistries（C18,Amide,Phenyl-hexyl and Peptide ES-C18） were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition（ACN or MeOH as organic modifier;formic acid or acetic acid,as acidifying component） on the column selectivity,peak shape and overall chromatographic performance were evaluated.The RP-amide column,combined with a formic acid-acetonitrile based gradient system,performed as best.A peptide reversed-phase retention model is proposed,consisting of 5 variables：log SumAA,log Sv,clog P,log nHDon and log nHAcc.Quantitative structure-retention relationship（QSRR） models were constructed for 16 different chromatographic systems.The accuracy of this peptide retention model was demonstrated by the comparison between predicted and experimentally obtained retention times,explaining on average 86% of the variability.Moreover,using an external set of 5 validation peptides,the predictive power of the model was also demonstrated.This peptide retention model includes the novel in-silico calculated amino acid descriptor,AA,which was calculated from log P,3D-MoRSE,RDF and WHIM descriptors.
