Nordihydroguaiaretic acid (NDGA) has been synthesized in nine steps from piperonal using Stobbe condensation as the key step with high yield. By this approach, five relative natural products were obtained.
基金We are grateful to the National Natural Science Foundation of China (NSFC QT program No.20172023) and Natural Science Foundation of Gansu province (ZS001-A25-003-Z).
文摘Nordihydroguaiaretic acid (NDGA) has been synthesized in nine steps from piperonal using Stobbe condensation as the key step with high yield. By this approach, five relative natural products were obtained.
