Clay,as the most common soil used for foundationfill,is widely used in various infrastructure projects.The phy-sical and mechanical properties of clay are influenced by the pore solution environment.This study uses a GD...Clay,as the most common soil used for foundationfill,is widely used in various infrastructure projects.The phy-sical and mechanical properties of clay are influenced by the pore solution environment.This study uses a GDS static/dynamic triaxial apparatus and nuclear magnetic resonance experiments to investigate the effects of cyclic loading on clay foundations.Moreover,the development of cumulative strain in clay is analyzed,and afitting model for cumulative plastic strain is introduced by considering factors such as NaCl solution concentration,con-solidation stress ratio,and cycle number.In particular,the effects of the NaCl solution concentration and con-solidation stress ratio on the pore distribution of the test samples before and after cyclic loading are examined,and the relationship between microscopic pore size and macroscopic cumulative strain is obtained accordingly.Our results show that as the consolidation stress ratio grows,an increasing number of large pores in the soil samples are transformed into small pores.As the NaCl solution concentration becomes higher,the number of small pores gradually decreases,while the number of large pores remains unchanged.Cyclic loading causes the disappearance of the large pores in the samples,and the average pore size before cyclic loading is posi-tively correlated with the axial cumulative strain after cyclic loading.The cumulative strain produced by the soil under cyclic loading is inversely proportional to the NaCl solution concentration and consolidation stress ratio.展开更多
The functionalities and diverse metastable phases of multiferroic BiFeO_(3)(BFO)thin films depend on the misfit strain.Although mixed phase-induced strain relaxation in multiphase BFO thin films is well known,it is un...The functionalities and diverse metastable phases of multiferroic BiFeO_(3)(BFO)thin films depend on the misfit strain.Although mixed phase-induced strain relaxation in multiphase BFO thin films is well known,it is unclear whether a singlecrystalline BFO thin film can accommodate misfit strain without the involvement of its polymorphs.Thus,understanding the strain relaxation behavior is key to elucidating the lattice strain–property relationship.In this study,a correlative strain analysis based on dark-field inline electron holography(DIH)and quantitative scanning transmission electron microscopy(STEM)was performed to reveal the structural mechanism for strain accommodation of a single-crystalline BFO thin film.The nanoscale DIH strain analysis results indicated a random combination of multiple strain states that acted as a primary strain relief,forming irregularly strained nanodomains.The STEM-based bond length measurement of the corresponding strained nanodomains revealed a unique strain accommodation behavior achieved by a statistical combination of multiple modes of distorted structures on the unit-cell scale.The globally integrated strain for each nanodomain was estimated to be close to1.5%,irrespective of the nanoscale strain states,which was consistent with the fully strained BFO film on the SrTiO_(3) substrate.Density functional theory calculations suggested that strain accommodation by the combination of metastable phases was energetically favored compared to single-phase-mediated relaxation.This discovery allows a comprehensive understanding of strain accommodation behavior in ferroelectric oxide films,such as BFO,with various low-symmetry polymorphs.展开更多
Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Walle...Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary behaviors.The preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion repair.In the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis rats.Mechanical nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the hindpaws.Dorsal von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve transections.Baseline withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not sex.Withdrawal thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated rats.Following sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the injury.However,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative Control rats.Furthermore,PEG-fused rats with significantly improved Sciatic Functional Index scores at or after 4 weeks postoperatively exhibited yet-earlier von Frey filament recove ry compared with those without Sciatic Functional Index recovery,suggesting a correlation between successful PEG-fusion and both motor-dominant and sensory-dominant behavioral recoveries.This correlation was independent of the sex or strain of the rat.Furthermore,our data showed that the acceleration of von Frey filament sensory recovery to baseline was solely due to the PEG-fused sciatic nerve and not saphenous nerve collateral outgrowths.No chronic hypersensitivity developed in any rat up to 12 weeks.All these data suggest that PEG-fusion repair of transection peripheral nerve injuries co uld have important clinical benefits.展开更多
[Objective] Strain Biok Av-023 used as the control was employed on screening of high-avermectin yield mutants by rational screening.[Method] With Biok Av-023 as the original strain,the positive mutation strain was fir...[Objective] Strain Biok Av-023 used as the control was employed on screening of high-avermectin yield mutants by rational screening.[Method] With Biok Av-023 as the original strain,the positive mutation strain was firstly screened by routine UV mutagenesis,and then the high-yield avermectin producing strain was selected by the breeding way inferred by L-Ile induction.[Result] UV mutation and L-Ile directional screening had showed that the best L-Ile screening concentration was 0.5%,and the high-yield mutation strain AV60s-32 after re-screening reached the highest titer of 4520 IU/ml,which increased by 23.4% compared with the original strain.[Conclusion] The production of avermectin can be effectively enhanced by the combined way of UV mutation and L-Ile rational breeding.展开更多
To develop modal macro-strain ( MMS ) identification techniques and improve their applicability in a continuous health monitoring system for civil infrastructures, the concept of operational macro-strain shape (OMS...To develop modal macro-strain ( MMS ) identification techniques and improve their applicability in a continuous health monitoring system for civil infrastructures, the concept of operational macro-strain shape (OMSS) and the corresponding identification method are proposed under unknown ever-changing loading conditions, and the MMS is then obtained. The core of the proposed technique is mainly based on the specific property that the macro-strain transmissibility tends to be independent of external excitations at the poles of the system and converges to a unique value. The proposed method is verified using the experimental data from a three-span continuous beam excited by an impact hammer at different locations. The identified results are also compared with the commonly used methods, such as the peak- picking (PP) method, the stochastic subspace identification (SSI) method, and numerical results, in the case of unknown input forces. Results show that the proposed technique has unique merits in accuracy and robustness due to its combining multiple tests under changing loading conditions, which also reveal the promising application of the distributed strain sensing system in identifying MMS of operational structures, as well as in the structural health monitoring (SHM) field.展开更多
This paper studied the effects of different ratios of nitrogen and phospho- rus on the growth and competition of Anabaena sp. strain PCC and chloralla vul- gads (low nitrogen-phosphorus ratio group: N/P=16:1; Mediu...This paper studied the effects of different ratios of nitrogen and phospho- rus on the growth and competition of Anabaena sp. strain PCC and chloralla vul- gads (low nitrogen-phosphorus ratio group: N/P=16:1; Medium low nitrogen-phospho- rus ratio group: N/P=32:1; Medium high nitrogen-phosphorus ratio group: N/P=64:1; High nitrogen-phosphorus ratio group: N/P=320:1). Results suggested that the largest amount of anabaena sp.strain PCC survived in medium high nitrogen-phosphorus ratio group. The nitrogen-phosphorus ratio showed no significant influences on the growth of Chlorella vulgaris, but it exerted dramatic influences on the growth of Chlore/la vulgaris of the mixed cultivation system. The largest amount of Ch/orel/a vulgaris can be found in the medium-high nitrogen-phosphorus ratio group. The inhi- bition parameter of nitrogen-phosphorus on the algae was distinctive. Anabaena sp. strain PCC had advantages in the competition with the low nitrogen-phosphorus ra- tio and medium-low nitrogen-phosphorus ratio. Potential instability existed between anabaena sp.strain PCC and Chlorella vulgaris when the nitrogen to phosphorus ratio was medium-high and high.展开更多
AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were ...AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL.展开更多
Due to traffic and wave actions, cast steel joints are subjected to variable-amplitude fatigue loading, which may cause fatigue problems. The ratio of the minimum strain to the maximum strain(strain ratio)can be emplo...Due to traffic and wave actions, cast steel joints are subjected to variable-amplitude fatigue loading, which may cause fatigue problems. The ratio of the minimum strain to the maximum strain(strain ratio)can be employed to analyze the influence of variable-amplitude fatigue both in the elastic and plastic ranges. To evaluate the effect of the strain ratio on G20Mn5 QT cast steel, the fatigue tests of smooth specimens were carried out at the strain ratio of 0.1. The cyclic deformation and the relationships between the strain amplitude, the stress amplitude, the Smith, Watson and Topper(SWT)parameter and fatigue life were studied and compared with those at the strain ratio of-1. Compared with other methods, Basquin formula and Solonberg formula provide reliable and appropriate ranges of S-N curve and fatigue limit at different strain ratios respectively. The SWT parameter can be used to predict the fatigue life at other strain ratios accurately.展开更多
The complete stress-strain characteristics of sandstone specimens were investigated in a series of quasistatic monotonic uniaxial compression tests.Strain patterns development during pre-and post-peak behaviours in sp...The complete stress-strain characteristics of sandstone specimens were investigated in a series of quasistatic monotonic uniaxial compression tests.Strain patterns development during pre-and post-peak behaviours in specimens with different aspect ratios was also examined.Peak stress,post-peak portion of stress-strain,brittleness,characteristics of progressive localisation and field strain patterns development were affected at different extents by specimen aspect ratio.Strain patterns of the rocks were obtained by applying three-dimensional(3D) digital image correlation(DIC) technique.Unlike conventional strain measurement using strain gauges attached to specimen,3D DIC allowed not only measuring large strains,but more importantly,mapping the development of field strain throughout the compression test,i.e.in pre-and post-peak regimes.Field strain development in the surface of rock specimen suggests that strain starts localising progressively and develops at a lower rate in pre-peak regime.However,in post-peak regime,strains increase at different rates as local deformations take place at different extents in the vicinity and outside the localised zone.The extent of localised strains together with the rate of strain localisation is associated with the increase in rate of strength degradation.Strain localisation and local inelastic unloading outside the localised zone both feature post-peak regime.展开更多
The behavior of soil-structure interface plays a major role in the definition of soil-structure interaction. In this paper a bi-potential surface elasto-plastic model for soil-structure interface is proposed in order ...The behavior of soil-structure interface plays a major role in the definition of soil-structure interaction. In this paper a bi-potential surface elasto-plastic model for soil-structure interface is proposed in order to describe the interface deformation behavior,including strain softening and normal dilatancy. The model is formulated in the framework of generalized potential theory,in which the soil-structure interface problem is regard as a two-dimensional mathematical problem in stress field,and plastic state equations are used to replace the traditional field surface. The relation curves of shear stress and tangential strain are fitted by a piecewise function composed by hyperbolic functions and hyperbolic secant functions,while the relation curves of normal strain and tangential strain are fitted by another piecewise function composed by quadratic functions and hyperbolic secant functions. The approach proposed has the advantage of deriving an elastoplastic constitutive matrix without postulating the plastic potential functions and yield surface. Moreover,the mathematical principle is clear,and the entire model parameters can be identified by experimental tests. Finally,the predictions of the model have been compared with experimental results obtained from simple shear tests under normal stresses,and results show the model is reasonable and practical.展开更多
Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability to stand explosion, immunity to electromagnetic interference and high accuracy, esp...Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability to stand explosion, immunity to electromagnetic interference and high accuracy, especially fit for measureroent applications in harsh environment. In this study, a novel FBG (fiber Bragg grating) strain sensor, which is packaged in a 1.2 mm stainless steel tube with epoxy resin, is developed. Experiments are conducted on the universal material testing machine to calibrate its strain transferring characteristics. The sensor has the advantages of small size, high precision and flexible use, and exhibits promising potentials. Five tube-packaged strain FBG sensors have been applied to the vibration experiment of a submarine pipeline model. The strain measttred with the FBG sensor agrees well with that measttred with the electric resistance strain sensor.展开更多
In this paper,we analytically study vibration of functionally graded piezoelectric(FGP)nanoplates based on the nonlocal strain gradient theory.The top and bottom surfaces of the nanoplate are made of PZT-5H and PZT-4,...In this paper,we analytically study vibration of functionally graded piezoelectric(FGP)nanoplates based on the nonlocal strain gradient theory.The top and bottom surfaces of the nanoplate are made of PZT-5H and PZT-4,respectively.We employ Hamilton’s principle and derive the governing differential equations.Then,we use Navier’s solution to obtain the natural frequencies of the FGP nanoplate.In the first step,we compare our results with the obtained results for the piezoelectric nanoplates in the previous studies.In the second step,we neglect the piezoelectric effect and compare our results with those obtained for the functionally graded(FG)nanoplates.Finally,the effects of the FG power index,the nonlocal parameter,the aspect ratio,and the lengthto-thickness ratio,and the nanoplate shape on natural frequencies are investigated.展开更多
Methane (CH4) emissions estimated with the Intergovernmental Panel on Climate Change (IPCC) inventory method at the city and regional scale are subject to large uncertainties.In this study,we determined the CH4:C...Methane (CH4) emissions estimated with the Intergovernmental Panel on Climate Change (IPCC) inventory method at the city and regional scale are subject to large uncertainties.In this study,we determined the CH4:CO2 emissions ratio for both Nanjing and the Yangtze River Delta (YRD),using the atmospheric CH4 and CO2 concentrations measured at a suburban site in Nanjing in the winter.The atmospheric estimate of the CH4:CO2 emissions ratio was in reasonable agreement with that calculated using the IPCC method for the YRD (within 20%),but was 200% greater for the municipality of Nanjing.The most likely reason for the discrepancy is that emissions from unmanaged landfills are omitted from the official statistics on garbage production.展开更多
Based on conservation of energy principle and heat flow data in China continent, the upper limit of 1.3 μW/m3 heat production is obtained for continental crust in China. Furthermore, using the data of heat flow and h...Based on conservation of energy principle and heat flow data in China continent, the upper limit of 1.3 μW/m3 heat production is obtained for continental crust in China. Furthermore, using the data of heat flow and helium isotope ratio of underground fluid, the heat productions of different tectonic units in China continent are estimated in range of 0.58-1.12 μW/m3 with a median of 0.85 μW/m3. Accordingly, the contents of U, Th and K20 in China crust are in ranges of 0.83-1.76 μg/g, 3.16-6.69 μg/g, and 1.0%-2.12%, respectively. These results indicate that the abundance of radioactive elements in the crust of China continent is much higher than that of Archean crust; and this fact implies China's continental crust is much evolved in chemical composition. Meanwhile, significant lateral variation of crustal composition is also exhibited among different tectonic units in China continent. The crust of eastern China is much enriched in incompatible elements such as U, Th and K than that of western China; and the crust of orogenic belts is more enriched than that of platform regions. It can also be inferred that the crusts of eastern China and orogenic belts are much felsic than those of western China and platform regions, respectively, derived from the positive correlation between the heat production and SiO2 content of bulk crust. This deduction is consistent with the results derived from the crustal seismic velocity data in China. According to the facts of the lower seismic velocity of China than the average value of global crust, and the higher heat production of China continent compared with global crust composition models published by previous studies, it is deduced that the average composition models of global continent crust by Rudnick and Fountain (1995), Rudnick and Gao (2003), Weaver and Tarney (1984), Shaw et al. (1986), and Wedepohl (1995) overestimate the abundance of incompatible elements such as U, Th and K of continental crust.展开更多
An investigation on strain amplitude-dependent internal friction (IF) of an as-cast high damping Mg-7 wt% Ni alloy was carried out. In the range of our tested strain amplitudes, whether the strain amplitude is incre...An investigation on strain amplitude-dependent internal friction (IF) of an as-cast high damping Mg-7 wt% Ni alloy was carried out. In the range of our tested strain amplitudes, whether the strain amplitude is increasing or decreasing, the strain amplitude-dependent IF curve can be divided into two stages: one is the strain amplitude weakly dependent part and the other is the strain amplitude strongly dependent part. However, after several cyclic vibrations, the IF values measured during the strain amplitude increasing are smaller than those obtained during the strain amplitude decreasing. The phenomenon is also observed at 100 C. Partial dislocations generate a short-range slip under the cyclic stress to be responsible for it.展开更多
In this pap er, a novel size-dep endent functionally graded (FG) cylindrical shell model is develop ed based on the nonlocal strain gradient theory in conjunction with the Gurtin-Murdoch surface elasticity theory . Th...In this pap er, a novel size-dep endent functionally graded (FG) cylindrical shell model is develop ed based on the nonlocal strain gradient theory in conjunction with the Gurtin-Murdoch surface elasticity theory . The new model containing a nonlocal parameter, a material length scale parameter, and several surface elastic constants can capture three typical typ es of size e ects simultaneously , which are the nonlocal stress ef- fect, the strain gradient e ect, and the surface energy e ects. With the help of Hamilton’s principle and rst-order shear deformation theory , the non-classical governing equations and related b oundary conditions are derived. By using the prop osed model, the free vibra- tion problem of FG cylindrical nanoshells with material prop erties varying continuously through the thickness according to a p ower-law distribution is analytically solved, and the closed-form solutions for natural frequencies under various b oundary conditions are obtained. After verifying the reliability of the prop osed model and analytical method by comparing the degenerated results with those available in the literature, the in uences of nonlocal parameter, material length scale parameter, p ower-law index, radius-to-thickness ratio, length-to-radius ratio, and surface e ects on the vibration characteristic of func- tionally graded cylindrical nanoshells are examined in detail.展开更多
End-to-end repair under no or low tension leads to improved outcomes for transected nerves with short gaps,compared to repairs with a graft.However,grafts are typically used to enable a tension-free repair for moderat...End-to-end repair under no or low tension leads to improved outcomes for transected nerves with short gaps,compared to repairs with a graft.However,grafts are typically used to enable a tension-free repair for moderate to large gaps,as excessive tension can cause repairs to fail and catastrophically impede recovery.In this study,we tested the hypothesis that unloading the repair interface by redistributing tension away from the site of repair is a safe and feasible strategy for end-to-end repair of larger nerve gaps.Further,we tested the hypothesis that such an approach does not adversely affect structural and functional regeneration.In this study,we used a rat sciatic nerve injury model to compare the integrity of repair and several regenerative outcomes following end-to-end repairs of nerve gaps of increasing size.In addition,we proposed the use of a novel implantable device to safely repair end-to-end repair of larger nerve gaps by redistributing tension away from the repair interface.Our data suggest that redistriubution of tension away from the site of repair enables safe end-to-end repair of larger gap sizes.In addition,structural and functional measures of regeneration were equal or enhanced in nerves repaired under tension – with or without a tension redistribution device – compared to tension-free repairs.Provided that repair integrity is maintained,end-to-end repairs under tension should be considered as a reasonable surgical strategy.All animal experiments were performed under the approval of the Institutional Animal Care and Use Committee of University of California,San Diego(Protocol S11274).展开更多
The effects of strain and chloride concentration on pitting susceptibility for type 304 stainless steel were studied in situ using the electrochemical technology under constant strain. The impact factor fc was brought...The effects of strain and chloride concentration on pitting susceptibility for type 304 stainless steel were studied in situ using the electrochemical technology under constant strain. The impact factor fc was brought forward to value the effect of strain on pitting. The pitting behaviors of type 304 stainless steel in various chloride concentrations under the strain levels 0%, 10%, and 30% were investigated. Potentiostatic polarization technology was used to study how the chloride concentration affected corrosion current density. The results indicated that fc increased substantially and pitting potential varied remarkably when chloride concentration was over 90 mg.L . Under the three levels of strain mentioned above, when chloride concentration was below 463 mg.L^-1,121 mg.L^-1, and 98 mg.L^-1 respectively, the pitting potential shifted towards positivity and, the passive film became more stable. When the strain was below 10%, the pitting susceptibility of type 304 stainless steel varied greatly as strain increased, whereas the susceptibility only changed a little when the strain was over 10%.展开更多
The rationality of using strain energy storage index(Wet)for evaluating rockburst proneness was theoretically verified based on linear energy storage(LES)law in this study.The LES law is defined as the linear relation...The rationality of using strain energy storage index(Wet)for evaluating rockburst proneness was theoretically verified based on linear energy storage(LES)law in this study.The LES law is defined as the linear relationship between the elastic strain energy stored inside the solid material and the input strain energy during loading.It is used to determine the elastic strain energy and dissipated strain energy of rock specimens at various loading/unloading stress levels.The results showed that the Wetvalue obtained from experiments was close to the corresponding theoretical one from the LES law.Furthermore,with an increase in the loading/unloading stress level,the ratio of elastic strain energy to dissipated strain energy converged to the peak-strength strain energy storage index(Wp et).This index is stable and can better reflect the relative magnitudes of the stored energy and the dissipated energy of rocks at the whole pre-peak stage than the strain energy storage index.The peak-strength strain energy storage index can replace the conventional strain energy storage index as a new index for evaluating rockburst proneness.展开更多
文摘Clay,as the most common soil used for foundationfill,is widely used in various infrastructure projects.The phy-sical and mechanical properties of clay are influenced by the pore solution environment.This study uses a GDS static/dynamic triaxial apparatus and nuclear magnetic resonance experiments to investigate the effects of cyclic loading on clay foundations.Moreover,the development of cumulative strain in clay is analyzed,and afitting model for cumulative plastic strain is introduced by considering factors such as NaCl solution concentration,con-solidation stress ratio,and cycle number.In particular,the effects of the NaCl solution concentration and con-solidation stress ratio on the pore distribution of the test samples before and after cyclic loading are examined,and the relationship between microscopic pore size and macroscopic cumulative strain is obtained accordingly.Our results show that as the consolidation stress ratio grows,an increasing number of large pores in the soil samples are transformed into small pores.As the NaCl solution concentration becomes higher,the number of small pores gradually decreases,while the number of large pores remains unchanged.Cyclic loading causes the disappearance of the large pores in the samples,and the average pore size before cyclic loading is posi-tively correlated with the axial cumulative strain after cyclic loading.The cumulative strain produced by the soil under cyclic loading is inversely proportional to the NaCl solution concentration and consolidation stress ratio.
基金Samsung Research Fundings&Incubation Center of Samsung Electronics(Grant No.SRFCMA1702-01)Y.-M.K acknowledges partial support from the National Research Foundation of Korea(NRF)(Grant No.2023R1A2C2002403)funded by the Korean government in KoreaA.Borisevich acknowledges support from FaCT,an Energy Frontier Research Center funded by the U.S.Department of Energy,Office of Science,Office of Basic Energy Science,Collaboratives Research Division.
文摘The functionalities and diverse metastable phases of multiferroic BiFeO_(3)(BFO)thin films depend on the misfit strain.Although mixed phase-induced strain relaxation in multiphase BFO thin films is well known,it is unclear whether a singlecrystalline BFO thin film can accommodate misfit strain without the involvement of its polymorphs.Thus,understanding the strain relaxation behavior is key to elucidating the lattice strain–property relationship.In this study,a correlative strain analysis based on dark-field inline electron holography(DIH)and quantitative scanning transmission electron microscopy(STEM)was performed to reveal the structural mechanism for strain accommodation of a single-crystalline BFO thin film.The nanoscale DIH strain analysis results indicated a random combination of multiple strain states that acted as a primary strain relief,forming irregularly strained nanodomains.The STEM-based bond length measurement of the corresponding strained nanodomains revealed a unique strain accommodation behavior achieved by a statistical combination of multiple modes of distorted structures on the unit-cell scale.The globally integrated strain for each nanodomain was estimated to be close to1.5%,irrespective of the nanoscale strain states,which was consistent with the fully strained BFO film on the SrTiO_(3) substrate.Density functional theory calculations suggested that strain accommodation by the combination of metastable phases was energetically favored compared to single-phase-mediated relaxation.This discovery allows a comprehensive understanding of strain accommodation behavior in ferroelectric oxide films,such as BFO,with various low-symmetry polymorphs.
基金supported by DOD AFIRMⅢW81XWH-20-2-0029 subcontract,UT POC19-1774-13Neuraptive Therapeutics Inc.26-7724-56+1 种基金NIH R01-NS128086 grantsLone Star Paralysis gift(to GDB)。
文摘Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary behaviors.The preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion repair.In the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis rats.Mechanical nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the hindpaws.Dorsal von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve transections.Baseline withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not sex.Withdrawal thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated rats.Following sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the injury.However,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative Control rats.Furthermore,PEG-fused rats with significantly improved Sciatic Functional Index scores at or after 4 weeks postoperatively exhibited yet-earlier von Frey filament recove ry compared with those without Sciatic Functional Index recovery,suggesting a correlation between successful PEG-fusion and both motor-dominant and sensory-dominant behavioral recoveries.This correlation was independent of the sex or strain of the rat.Furthermore,our data showed that the acceleration of von Frey filament sensory recovery to baseline was solely due to the PEG-fused sciatic nerve and not saphenous nerve collateral outgrowths.No chronic hypersensitivity developed in any rat up to 12 weeks.All these data suggest that PEG-fusion repair of transection peripheral nerve injuries co uld have important clinical benefits.
基金Supported by 863 Project (2009AA032904 )Scientific ResearchStarting-up Project for Young Teachers in Changshu Institute oTechnology" Hundreds of Entrepreneurs into Campus" Project inChangshu Institute of Technology~~
文摘[Objective] Strain Biok Av-023 used as the control was employed on screening of high-avermectin yield mutants by rational screening.[Method] With Biok Av-023 as the original strain,the positive mutation strain was firstly screened by routine UV mutagenesis,and then the high-yield avermectin producing strain was selected by the breeding way inferred by L-Ile induction.[Result] UV mutation and L-Ile directional screening had showed that the best L-Ile screening concentration was 0.5%,and the high-yield mutation strain AV60s-32 after re-screening reached the highest titer of 4520 IU/ml,which increased by 23.4% compared with the original strain.[Conclusion] The production of avermectin can be effectively enhanced by the combined way of UV mutation and L-Ile rational breeding.
基金The National Natural Science Foudation of China(No.51578140)the Natural Science Foundation of Jiangsu Province(No.BK20151092)Scientific Innovation Research of College Graduates in Jiangsu Province(No.CXZZ12_0108)
文摘To develop modal macro-strain ( MMS ) identification techniques and improve their applicability in a continuous health monitoring system for civil infrastructures, the concept of operational macro-strain shape (OMSS) and the corresponding identification method are proposed under unknown ever-changing loading conditions, and the MMS is then obtained. The core of the proposed technique is mainly based on the specific property that the macro-strain transmissibility tends to be independent of external excitations at the poles of the system and converges to a unique value. The proposed method is verified using the experimental data from a three-span continuous beam excited by an impact hammer at different locations. The identified results are also compared with the commonly used methods, such as the peak- picking (PP) method, the stochastic subspace identification (SSI) method, and numerical results, in the case of unknown input forces. Results show that the proposed technique has unique merits in accuracy and robustness due to its combining multiple tests under changing loading conditions, which also reveal the promising application of the distributed strain sensing system in identifying MMS of operational structures, as well as in the structural health monitoring (SHM) field.
基金Supported by Modern Agricultural Production Technological System Construction(No:CARS-49)Central Public-Interest Scientific Institution Basal Research Fund(No:2013JBFM06)Jiangsu Wuxi Agricultural Scientific Cooperation Program~~
文摘This paper studied the effects of different ratios of nitrogen and phospho- rus on the growth and competition of Anabaena sp. strain PCC and chloralla vul- gads (low nitrogen-phosphorus ratio group: N/P=16:1; Medium low nitrogen-phospho- rus ratio group: N/P=32:1; Medium high nitrogen-phosphorus ratio group: N/P=64:1; High nitrogen-phosphorus ratio group: N/P=320:1). Results suggested that the largest amount of anabaena sp.strain PCC survived in medium high nitrogen-phosphorus ratio group. The nitrogen-phosphorus ratio showed no significant influences on the growth of Chlorella vulgaris, but it exerted dramatic influences on the growth of Chlore/la vulgaris of the mixed cultivation system. The largest amount of Ch/orel/a vulgaris can be found in the medium-high nitrogen-phosphorus ratio group. The inhi- bition parameter of nitrogen-phosphorus on the algae was distinctive. Anabaena sp. strain PCC had advantages in the competition with the low nitrogen-phosphorus ra- tio and medium-low nitrogen-phosphorus ratio. Potential instability existed between anabaena sp.strain PCC and Chlorella vulgaris when the nitrogen to phosphorus ratio was medium-high and high.
文摘AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL.
基金Supported by the National Natural Science Foundation of China(No.51178307 and No.51525803)
文摘Due to traffic and wave actions, cast steel joints are subjected to variable-amplitude fatigue loading, which may cause fatigue problems. The ratio of the minimum strain to the maximum strain(strain ratio)can be employed to analyze the influence of variable-amplitude fatigue both in the elastic and plastic ranges. To evaluate the effect of the strain ratio on G20Mn5 QT cast steel, the fatigue tests of smooth specimens were carried out at the strain ratio of 0.1. The cyclic deformation and the relationships between the strain amplitude, the stress amplitude, the Smith, Watson and Topper(SWT)parameter and fatigue life were studied and compared with those at the strain ratio of-1. Compared with other methods, Basquin formula and Solonberg formula provide reliable and appropriate ranges of S-N curve and fatigue limit at different strain ratios respectively. The SWT parameter can be used to predict the fatigue life at other strain ratios accurately.
基金supported by the Deep Exploration Technologies Cooperative Research Centre whose activities are funded by the Australian Government's Cooperative Research Centre Programme.This is DET CRC Document 2017/954
文摘The complete stress-strain characteristics of sandstone specimens were investigated in a series of quasistatic monotonic uniaxial compression tests.Strain patterns development during pre-and post-peak behaviours in specimens with different aspect ratios was also examined.Peak stress,post-peak portion of stress-strain,brittleness,characteristics of progressive localisation and field strain patterns development were affected at different extents by specimen aspect ratio.Strain patterns of the rocks were obtained by applying three-dimensional(3D) digital image correlation(DIC) technique.Unlike conventional strain measurement using strain gauges attached to specimen,3D DIC allowed not only measuring large strains,but more importantly,mapping the development of field strain throughout the compression test,i.e.in pre-and post-peak regimes.Field strain development in the surface of rock specimen suggests that strain starts localising progressively and develops at a lower rate in pre-peak regime.However,in post-peak regime,strains increase at different rates as local deformations take place at different extents in the vicinity and outside the localised zone.The extent of localised strains together with the rate of strain localisation is associated with the increase in rate of strength degradation.Strain localisation and local inelastic unloading outside the localised zone both feature post-peak regime.
基金supported by the National Natural Science Foundation of ChinaYalona River Hydropower Development of Ertan Hydropower Development Company (No.50639050)
文摘The behavior of soil-structure interface plays a major role in the definition of soil-structure interaction. In this paper a bi-potential surface elasto-plastic model for soil-structure interface is proposed in order to describe the interface deformation behavior,including strain softening and normal dilatancy. The model is formulated in the framework of generalized potential theory,in which the soil-structure interface problem is regard as a two-dimensional mathematical problem in stress field,and plastic state equations are used to replace the traditional field surface. The relation curves of shear stress and tangential strain are fitted by a piecewise function composed by hyperbolic functions and hyperbolic secant functions,while the relation curves of normal strain and tangential strain are fitted by another piecewise function composed by quadratic functions and hyperbolic secant functions. The approach proposed has the advantage of deriving an elastoplastic constitutive matrix without postulating the plastic potential functions and yield surface. Moreover,the mathematical principle is clear,and the entire model parameters can be identified by experimental tests. Finally,the predictions of the model have been compared with experimental results obtained from simple shear tests under normal stresses,and results show the model is reasonable and practical.
基金This research was financially supported by the National Natural Science Foundation of China ( Nos . 50408031 ,50378012 and 50439010) the Natural Science Foundation of Liaoning Province (Nos .20032210 and 20042149)the Young Teacher’s Foundationfrom Dalian University of Technology.
文摘Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability to stand explosion, immunity to electromagnetic interference and high accuracy, especially fit for measureroent applications in harsh environment. In this study, a novel FBG (fiber Bragg grating) strain sensor, which is packaged in a 1.2 mm stainless steel tube with epoxy resin, is developed. Experiments are conducted on the universal material testing machine to calibrate its strain transferring characteristics. The sensor has the advantages of small size, high precision and flexible use, and exhibits promising potentials. Five tube-packaged strain FBG sensors have been applied to the vibration experiment of a submarine pipeline model. The strain measttred with the FBG sensor agrees well with that measttred with the electric resistance strain sensor.
文摘In this paper,we analytically study vibration of functionally graded piezoelectric(FGP)nanoplates based on the nonlocal strain gradient theory.The top and bottom surfaces of the nanoplate are made of PZT-5H and PZT-4,respectively.We employ Hamilton’s principle and derive the governing differential equations.Then,we use Navier’s solution to obtain the natural frequencies of the FGP nanoplate.In the first step,we compare our results with the obtained results for the piezoelectric nanoplates in the previous studies.In the second step,we neglect the piezoelectric effect and compare our results with those obtained for the functionally graded(FG)nanoplates.Finally,the effects of the FG power index,the nonlocal parameter,the aspect ratio,and the lengthto-thickness ratio,and the nanoplate shape on natural frequencies are investigated.
基金supported by the Ministry of Education of China (Grant PCSIRT)the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)+2 种基金the National Natural Science Foundation of China (Grant No.31100359)the Natural Science Foundation of Jiangsu Province (Grant No.BK2011830)the Ningbo Planning Project of Science and Technology (Grant No.2012C50044)
文摘Methane (CH4) emissions estimated with the Intergovernmental Panel on Climate Change (IPCC) inventory method at the city and regional scale are subject to large uncertainties.In this study,we determined the CH4:CO2 emissions ratio for both Nanjing and the Yangtze River Delta (YRD),using the atmospheric CH4 and CO2 concentrations measured at a suburban site in Nanjing in the winter.The atmospheric estimate of the CH4:CO2 emissions ratio was in reasonable agreement with that calculated using the IPCC method for the YRD (within 20%),but was 200% greater for the municipality of Nanjing.The most likely reason for the discrepancy is that emissions from unmanaged landfills are omitted from the official statistics on garbage production.
基金supported by the National Natural Science Foundation of China (Grants Nos. 40376013, 40572128, and 40104003)
文摘Based on conservation of energy principle and heat flow data in China continent, the upper limit of 1.3 μW/m3 heat production is obtained for continental crust in China. Furthermore, using the data of heat flow and helium isotope ratio of underground fluid, the heat productions of different tectonic units in China continent are estimated in range of 0.58-1.12 μW/m3 with a median of 0.85 μW/m3. Accordingly, the contents of U, Th and K20 in China crust are in ranges of 0.83-1.76 μg/g, 3.16-6.69 μg/g, and 1.0%-2.12%, respectively. These results indicate that the abundance of radioactive elements in the crust of China continent is much higher than that of Archean crust; and this fact implies China's continental crust is much evolved in chemical composition. Meanwhile, significant lateral variation of crustal composition is also exhibited among different tectonic units in China continent. The crust of eastern China is much enriched in incompatible elements such as U, Th and K than that of western China; and the crust of orogenic belts is more enriched than that of platform regions. It can also be inferred that the crusts of eastern China and orogenic belts are much felsic than those of western China and platform regions, respectively, derived from the positive correlation between the heat production and SiO2 content of bulk crust. This deduction is consistent with the results derived from the crustal seismic velocity data in China. According to the facts of the lower seismic velocity of China than the average value of global crust, and the higher heat production of China continent compared with global crust composition models published by previous studies, it is deduced that the average composition models of global continent crust by Rudnick and Fountain (1995), Rudnick and Gao (2003), Weaver and Tarney (1984), Shaw et al. (1986), and Wedepohl (1995) overestimate the abundance of incompatible elements such as U, Th and K of continental crust.
基金financially supported by the Natural Science Foundation of Jiangxi Province(No. 20114BAB216015)Natural Science Foundation of China(No. 50671083)
文摘An investigation on strain amplitude-dependent internal friction (IF) of an as-cast high damping Mg-7 wt% Ni alloy was carried out. In the range of our tested strain amplitudes, whether the strain amplitude is increasing or decreasing, the strain amplitude-dependent IF curve can be divided into two stages: one is the strain amplitude weakly dependent part and the other is the strain amplitude strongly dependent part. However, after several cyclic vibrations, the IF values measured during the strain amplitude increasing are smaller than those obtained during the strain amplitude decreasing. The phenomenon is also observed at 100 C. Partial dislocations generate a short-range slip under the cyclic stress to be responsible for it.
基金Project supported by the National Natural Science Foundation of China(Nos.11872233 and11472163)the China Scholarship Council(No.201706890041)the Innovation Program of Shanghai Municipal Education Commission(No.2017-01-07-00-09-E00019)
文摘In this pap er, a novel size-dep endent functionally graded (FG) cylindrical shell model is develop ed based on the nonlocal strain gradient theory in conjunction with the Gurtin-Murdoch surface elasticity theory . The new model containing a nonlocal parameter, a material length scale parameter, and several surface elastic constants can capture three typical typ es of size e ects simultaneously , which are the nonlocal stress ef- fect, the strain gradient e ect, and the surface energy e ects. With the help of Hamilton’s principle and rst-order shear deformation theory , the non-classical governing equations and related b oundary conditions are derived. By using the prop osed model, the free vibra- tion problem of FG cylindrical nanoshells with material prop erties varying continuously through the thickness according to a p ower-law distribution is analytically solved, and the closed-form solutions for natural frequencies under various b oundary conditions are obtained. After verifying the reliability of the prop osed model and analytical method by comparing the degenerated results with those available in the literature, the in uences of nonlocal parameter, material length scale parameter, p ower-law index, radius-to-thickness ratio, length-to-radius ratio, and surface e ects on the vibration characteristic of func- tionally graded cylindrical nanoshells are examined in detail.
基金supported by the Department of Veterans Affairs(VA MERIT IRX001471A to SBS)
文摘End-to-end repair under no or low tension leads to improved outcomes for transected nerves with short gaps,compared to repairs with a graft.However,grafts are typically used to enable a tension-free repair for moderate to large gaps,as excessive tension can cause repairs to fail and catastrophically impede recovery.In this study,we tested the hypothesis that unloading the repair interface by redistributing tension away from the site of repair is a safe and feasible strategy for end-to-end repair of larger nerve gaps.Further,we tested the hypothesis that such an approach does not adversely affect structural and functional regeneration.In this study,we used a rat sciatic nerve injury model to compare the integrity of repair and several regenerative outcomes following end-to-end repairs of nerve gaps of increasing size.In addition,we proposed the use of a novel implantable device to safely repair end-to-end repair of larger nerve gaps by redistributing tension away from the repair interface.Our data suggest that redistriubution of tension away from the site of repair enables safe end-to-end repair of larger gap sizes.In addition,structural and functional measures of regeneration were equal or enhanced in nerves repaired under tension – with or without a tension redistribution device – compared to tension-free repairs.Provided that repair integrity is maintained,end-to-end repairs under tension should be considered as a reasonable surgical strategy.All animal experiments were performed under the approval of the Institutional Animal Care and Use Committee of University of California,San Diego(Protocol S11274).
文摘The effects of strain and chloride concentration on pitting susceptibility for type 304 stainless steel were studied in situ using the electrochemical technology under constant strain. The impact factor fc was brought forward to value the effect of strain on pitting. The pitting behaviors of type 304 stainless steel in various chloride concentrations under the strain levels 0%, 10%, and 30% were investigated. Potentiostatic polarization technology was used to study how the chloride concentration affected corrosion current density. The results indicated that fc increased substantially and pitting potential varied remarkably when chloride concentration was over 90 mg.L . Under the three levels of strain mentioned above, when chloride concentration was below 463 mg.L^-1,121 mg.L^-1, and 98 mg.L^-1 respectively, the pitting potential shifted towards positivity and, the passive film became more stable. When the strain was below 10%, the pitting susceptibility of type 304 stainless steel varied greatly as strain increased, whereas the susceptibility only changed a little when the strain was over 10%.
基金supported by the National Natural Science Foundation of China(Grant Nos.42077244 and 41877272)the Fundamental Research Funds for the Central Universities(Grant No.2242022k30054)。
文摘The rationality of using strain energy storage index(Wet)for evaluating rockburst proneness was theoretically verified based on linear energy storage(LES)law in this study.The LES law is defined as the linear relationship between the elastic strain energy stored inside the solid material and the input strain energy during loading.It is used to determine the elastic strain energy and dissipated strain energy of rock specimens at various loading/unloading stress levels.The results showed that the Wetvalue obtained from experiments was close to the corresponding theoretical one from the LES law.Furthermore,with an increase in the loading/unloading stress level,the ratio of elastic strain energy to dissipated strain energy converged to the peak-strength strain energy storage index(Wp et).This index is stable and can better reflect the relative magnitudes of the stored energy and the dissipated energy of rocks at the whole pre-peak stage than the strain energy storage index.The peak-strength strain energy storage index can replace the conventional strain energy storage index as a new index for evaluating rockburst proneness.