The potential mechanism and clinical application value of remote ischemic conditioning in stroke

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.

Actuator fault diagnosis and severity identification of turbofan engines for steady-state and dynamic conditions

Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from both academia and industry.However,the extensive literature that exists on this topic does not address identifying the severity of actuator faults and focuses mainly on actuator fault detection and isolation.In addition,previous studies of actuator fault identification have not dealt with multiple concurrent faults in real time,especially when these are accompanied by sudden failures under dynamic conditions.This study develops component-level models for fault identification in four typical actuators used in high-bypass ratio turbofan engines under both dynamic and steady-state conditions and these are then integrated with the engine performance model developed by the authors.The research results reported here present a novel method of quantifying actuator faults using dynamic effect compensation.The maximum error for each actuator is less than0.06%and 0.07%,with average computational time of less than 0.0058 s and 0.0086 s for steady-state and transient cases,respectively.These results confirm that the proposed method can accurately and efficiently identify concurrent actuator fault for an engine operating under either transient or steady-state conditions,even in the case of a sudden malfunction.The research results emonstrate the potential benefit to emergency response capabilities by introducing this method of monitoring the health of aero engines.

FedCLCC:A personalized federated learning algorithm for edge cloud collaboration based on contrastive learning and conditional computing

Federated learning(FL)is a distributed machine learning paradigm for edge cloud computing.FL can facilitate data-driven decision-making in tactical scenarios,effectively addressing both data volume and infrastructure challenges in edge environments.However,the diversity of clients in edge cloud computing presents significant challenges for FL.Personalized federated learning(pFL)received considerable attention in recent years.One example of pFL involves exploiting the global and local information in the local model.Current pFL algorithms experience limitations such as slow convergence speed,catastrophic forgetting,and poor performance in complex tasks,which still have significant shortcomings compared to the centralized learning.To achieve high pFL performance,we propose FedCLCC:Federated Contrastive Learning and Conditional Computing.The core of FedCLCC is the use of contrastive learning and conditional computing.Contrastive learning determines the feature representation similarity to adjust the local model.Conditional computing separates the global and local information and feeds it to their corresponding heads for global and local handling.Our comprehensive experiments demonstrate that FedCLCC outperforms other state-of-the-art FL algorithms.

Riemann-Hilbert Problem and Multiple High-order Poles Solutions of the Focusing mKdV Equation with Nonzero Boundary Conditions

The focusing modified Korteweg-de Vries(mKdV)equation with multiple high-order poles under the nonzero boundary conditions is first investigated via developing a Riemann-Hilbert(RH)approach.We begin with the asymptotic property,symmetry and analyticity of the Jost solutions,and successfully construct the RH problem of the focusing mKdV equation.We solve the RH problem when 1/S_(11)(k)has a single highorder pole and multiple high-order poles.Furthermore,we derive the soliton solutions of the focusing mKdV equation which corresponding with a single high-order pole and multiple high-order poles,respectively.Finally,the dynamics of one-and two-soliton solutions are graphically discussed.

Necessary and Sufficient Conditions in Smooth Programming with Generalized Convexity

Hanson and Mond have grven sets of necessary and sufficient conditions for optimality in constrained optimization by introducing classes of generalized functions, called type Ⅰ functions. Recently, Bector definded univex functions, a new class of functions that unifies several concepts of generalized convexity. In this paper, additional conditions are attached to the Kuhn Tucker conditions giving a set of conditions which are both necessary and sufficient for optimality in constrained optimization, under appropriate constraint qualifications.

A NECESSARY AND SUFFICIENT CONDITION FOR SINGULAR NONLINEAR SECOND-ORDER BOUNDARY VALUE PROBLEMS TO HAVE POSITIVE SOLUTIONS

In this paper the following result is obtained: Suppose f(x,u,v) is nonnegative, continuous in ( a, b)×R +×R +; f may be singular at x=a (and/or x=b ) and v=0; f is nondecreasing on u for each x,v, nonincreasing on v for each x,u; there exists a constant q∈(0,1) such that t qf(x,t -1 u,tu)f(x,u,u)λ qf(x,λ -1 u,λu),0<t<1<λ, u∈R +. Then a necessary and sufficient condition for the equation u″+f(x,u,u)=0 on the boundary condition αu(a)-βu′(a)=0, γ(b)+δu′(b)=0 to have C 1(I) nonzero solutions is that 0<∫ b af(x,e(x),e(x))dx<∞, where α,β,γ,δ are nonnegative real numbers, Δ=(b-a)αγ+αδ+βγ>0, e(x)=G(x,x), G(x,y) is Green's function of above mentioned boundary value problem (when f(x,u,v)≡0). Received September 9,1996. Revised March 31,1997. 1991 MR Subject Classification: 34B.

New sufficient conditions for general linear SISO Takagi-Sugeno fuzzy systems as universal approximators

By the best approximation theory, it is first proved that the SISO （single-input single-output） linear Takagi-Sugeno （TS） fuzzy systems can approximate an arbitrary polynomial which, according to Weierstrass approximation theorem, can uniformly approximate any continuous functions on the compact domain. Then new sufficient conditions for general linear SISO TS fuzzy systems as universal approximators are obtained. Formulae are derived to calculate the number of input fuzzy sets to satisfy the given approximation accuracy. Then the presented result is compared with the existing literature＇s results. The comparison shows that the presented result needs less input fuzzy sets, which can simplify the design of the fuzzy system, and examples are given to show its effectiveness.

Sufficient conditions of Rayleigh-Taylor stability and instability in equatorial ionosphere

Rayleigh-Taylor （R-T） instability is known as the fundamental mechanism of equatorial plasma bubbles （EPBs）. However, the sufficient conditions of R-T instability and stability have not yet been derived. In the present paper, the sufficient conditions of R-T stability and instability are preliminarily^derived. Linear equations for small perturbation are first obtained from the electron/ion continuity equations, momentum equations, and the current continuity equation in the equatorial ionosphere. The linear equations can be casted as an eigenvalue equation using a normal mode method. The eigenvalue equation is a variable coefficient linear equation that can be solved using a variational approach. With this approach, the sufficient conditions can be obtained as follows： if the minimum systematic eigenvalue is greater than one, the ionosphere is R-T unstable; while if the maximum systematic eigenvalue is less than one, the ionosphere is R-T stable. An approximate numerical method for obtaining the systematic eigenvalues is introduced, and the R-T stable/unstable areas are calculated. Numerical experiments axe designed to validate the sufficient conditions. The results agree with the derived suf- ficient conditions.

ON THE NECESSARY AND SUFFICIENT CONDITIONS TO SOLVE A HEAT EQUATION WITH GENERAL ADDITIVE GAUSSIAN NOISE

In this note, we consider stochastic heat equation with general additive Gaussian noise. Our aim is to derive some necessary and sufficient conditions on the Gaussian noise in order to solve the corresponding heat equation. We investigate this problem invoking two differen t met hods, respectively, based on variance compu tations and on pat h-wise considerations in Besov spaces. We are going to see that, as anticipated, both approaches lead to the same necessary and sufficient condition on the noise. In addition, the path-wise approach brings out regularity results for the solution.

Sufficient Optimality Conditions for Multiobjective Programming Involving (V, ρ)h,ψ-type Ⅰ Functions

New classes of functions namely (V, ρ)_(h,φ)-type I, quasi (V, ρ)_(h,φ)-type I and pseudo (V, ρ)_(h,φ)-type I functions are defined for multiobjective programming problem by using BenTal's generalized algebraic operation. The examples of (V, ρ)_(h,φ)-type I functions are given. The sufficient optimality conditions are obtained for multi-objective programming problem involving above new generalized convexity.

Necessary and Sufficient Conditions for Reactive Azeotropes in Multi-reaction Mixtures in Terms of Elemental Composition

Necessary and sufficient conditions for azeotropy in reactive mixtures are derived in terms of elemental composition, which shows that in the space of elemental compositions, they take the same functional form as the conditions for azeotropy in non-reactive mixtures. The production of methyl tert-butyl ether (MTBE) is taken as an example. It is found that there are a 'pseudo' intermediate-boiling ternary reactive azeotrope at p = 101.325kPa and two 'real' ternary reactive azeotropes at p = 101.325 Pa. The introduced elemental compositions also reduce the dimensionality of the phase diagrams and provide a natural set of variables for visualization of phase behavior.

SIMPLE SUFFICIENT CONDITIONS OF NONSINGULAR H-MATRICES

1 IntroductionH-matrices have important role in numerical analysis and matrix theory,etc.In thispaper,several practical criteria for H-matrices are obtained,to which the matrix is notnecessary be a diagonally dominant matrix,and the numbers of rows which are not diago-nal dominant can be n-1.We introduce the concept of α-diagonally dominant matrix,andby using the concept to investigate H-matrices.

NECESSARY AND SUFFICIENT CONDITIONS OF EXISTENCE AND UNIQUENESS OF LIMIT CYCLES FOR A CLASS OF POLYNOMIAL SYSTEM

In this paper, we discuss the limit cycles of the systemdx/dt=y·[1+(A(x)]oy/dt=(-x+δy+α_1x^2+α_2xy+α_5x^2y)[1+B(x)] (1)where A(x)=sum form i=1 to n(a_ix~), B(x)=sum form j=1 to m(β_jx^j) and 1+B(x)>0. We prove that (1) possesses at most one limit cycle and give out the necessary and sufficient conditions of existence and uniqueness of limit cycles.

A NECESSARY AND A SUFFICIENT CONDITION FOR THE EXISTENCE OF THE POSITIVE RADIAL SOLUTIONS TO HESSIAN EQUATIONS AND SYSTEMS WITH WEIGHTS

In this article, we consider the existence of positive radial solutions for Hessian equations and systems with weights and we give a necessary condition as well as a sufficient condition for a positive radial solution to be large. The method of proving theorems is essentially based on a successive approximation technique. Our results complete and improve a work published recently by Zhang and Zhou（existence of entire positive k-convex radial solutions to Hessian equations and systems with weights. Applied Mathematics Letters,Volume 50, December 2015, Pages 48–55）.

Comparison on Sufficient Conditions for the Stability of Hill Equation: An Arnold’s Tongues Approach

It is known that the solutions of a second order linear differential equation with periodic coefficients are almost always analytically impossible to obtain and in order to study its properties we often require a computational approach. In this paper we compare graphically, using the Arnold Tongues, some sufficient criteria for the stability of periodic differential equations. We also present a brief explanation on how the authors, of each criterion, obtained them. And a comparison between four sufficient stability criteria and the stability zones found by perturbation methods is presented.

A SUFFICIENT CONDITION OF CONVERGENCE FOR CLIFFORD CONTINUED FRACTIONS

In this article, a sufficient condition for a Clifford continued fraction to be convergent is established, and some applications are given.

ON A CLASS OF BESICOVITCH FUNCTIONS TO HAVE EXACT BOX DIMENSION: A NECESSARY AND SUFFICIENT CONDITION

This paper summarized recent achievements obtained by the authors about the box dimensions of the Besicovitch functions given bywhere 1 < s < 2, λk> tends to infinity as k→∞ and λk satisfies λk+1/λk≥λ>1. The results show thatis a necessary and sufficient condition for Graph(B(t)) to have same upper and lower box dimensions. For the fractional Riemann-Liouvtlle differential operator Du and the fractional integral operator D-v, the results show that if A is sufficiently large, then a necessary and sufficient condition for box dimensionof Graph(D-v(B)), 0 < v < s - 1, to be s - v and box dimension of Graph(Du(B)), 0 < u < 2 - s, to bes + u is also lim.

The convergence rate and necessary-and-sufficient condition for the consistency of isogeometric collocation method

Although the isogeometric collocation(IGA-C)method has been successfully utilized in practical applications due to its simplicity and efficiency,only a little theoretical results have been established on the numerical analysis of the IGA-C method.In this paper,we deduce the convergence rate of the consistency of the IGA-C method.Moreover,based on the formula of the convergence rate,the necessary and sufficient condition for the consistency of the IGA-C method is developed.These results advance the numerical analysis of the IGA-C method.

A NEW SUFFICIENT CONDITION FOR SPARSE RECOVERY WITH MULTIPLE ORTHOGONAL LEAST SQUARES

A greedy algorithm used for the recovery of sparse signals,multiple orthogonal least squares(MOLS)have recently attracted quite a big of attention.In this paper,we consider the number of iterations required for the MOLS algorithm for recovery of a K-sparse signal x∈R^(n).We show that MOLS provides stable reconstruction of all K-sparse signals x from y=Ax+w in|6K/ M|iterations when the matrix A satisfies the restricted isometry property(RIP)with isometry constantδ_(7K)≤0.094.Compared with the existing results,our sufficient condition is not related to the sparsity level K.

SUFFICIENT AND NECESSARY CONDITIONS ON THE EXISTENCE AND ESTIMATES OF BOUNDARY BLOW-UP SOLUTIONS FOR SINGULAR p-LAPLACIAN EQUATIONS

Let?denote a smooth,bounded domain in R^(N)(N≥2).Suppose that g is a nondecreasing C^(1)positive function and assume that b(x)is continuous and nonnegative inΩ,and that it may be singular on■Ω.In this paper,we provide sufficient and necessary conditions on the existence of boundary blow-up solutions to the p-Laplacian problem△_(p)u=b(x)g(u)for x∈Ω,u(x)→+∞as dist(x,■Ω)→0.The estimates of such solutions are also investigated.Moreover,when b has strong singularity,the nonexistence of boundary blow-up(radial)solutions and infinitely many radial solutions are also considered.