Compound action potentials (CAP) and action potential-summating potential com-plex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the posit...Compound action potentials (CAP) and action potential-summating potential com-plex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the positive and negative summating potentials (SP+ and SP-) were examined befroe and after impulse sound exposure. The results show that the SP-is related to CAP threshold shift. In comparison to normai condition, it appears with high incidence when auditory threshold shift reaches 30 dB or more. SP- increases in amplitude when SP+ decreases. The smaller the amplitude of SP+, the larger that of SP-. This suggests that in normai hearing condition SP- may be suppressed by SP+. Such suppression may be released if OHC are injured. The dominant SP- as a sign of recruitment may be due to the change in the nonlinear character of IHC following OHC damage.展开更多
Compound action potentials (CAP) and action potential-summating potential complex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the positi...Compound action potentials (CAP) and action potential-summating potential complex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the positive and negative summating potentials (SP+ and SP-) were examined before and after impulse sound exposure. The results show that the SP- is related to the threshold shift of CAP. In comparison to normal condition, it appears with a high incidence when the auditory threshold shift reaches 30 dB or more. SP-increases in amplitude when SP+ decreases. The smaller the amplitude of SP+, the larger that of SP-. This suggests that in normal hearing condition SP- may be suppressed by SP+. Such suppression may be released if OHCs are injured. The dominant SP- as a sign of recruitment may be due to the change in the nonlinear character of IHC following OHC damage.展开更多
基金This work was supported by the National Natural Science Foundation of China (39470744)
文摘Compound action potentials (CAP) and action potential-summating potential com-plex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the positive and negative summating potentials (SP+ and SP-) were examined befroe and after impulse sound exposure. The results show that the SP-is related to CAP threshold shift. In comparison to normai condition, it appears with high incidence when auditory threshold shift reaches 30 dB or more. SP- increases in amplitude when SP+ decreases. The smaller the amplitude of SP+, the larger that of SP-. This suggests that in normai hearing condition SP- may be suppressed by SP+. Such suppression may be released if OHC are injured. The dominant SP- as a sign of recruitment may be due to the change in the nonlinear character of IHC following OHC damage.
文摘Compound action potentials (CAP) and action potential-summating potential complex (AP-SP) evoked by click and tone burst respectively were recorded from the round window in guinea pigs. Correlations between the positive and negative summating potentials (SP+ and SP-) were examined before and after impulse sound exposure. The results show that the SP- is related to the threshold shift of CAP. In comparison to normal condition, it appears with a high incidence when the auditory threshold shift reaches 30 dB or more. SP-increases in amplitude when SP+ decreases. The smaller the amplitude of SP+, the larger that of SP-. This suggests that in normal hearing condition SP- may be suppressed by SP+. Such suppression may be released if OHCs are injured. The dominant SP- as a sign of recruitment may be due to the change in the nonlinear character of IHC following OHC damage.
