There are 36 counties affirmed to be aid-poverty-development county in the early 21st century, which distribute around the circumferential mountain of Sichuan Basin, According to the topographic features and the distr...There are 36 counties affirmed to be aid-poverty-development county in the early 21st century, which distribute around the circumferential mountain of Sichuan Basin, According to the topographic features and the distribution of nationality, these aid-poverty-development counties can be classified into 4 depressed-regions. Study shows that regional poverty performance of 4 depressed-regions not only has many commons in the field of regional economic structure and industry structure, which is far behind the average development performance of Sichuan in the field of economic sum per capita such as GDP, farmer net income per capita as well as retail scale consumer goods, it is also quite different related to infrastructure and social development within 4 depressed-regions. Regional Poverty is chronically resulted in interaction of the multi-factors. Natural condition constraint is the basic factor contributed to regional poverty, policy influences play key role, the poor culture is inherent factor to regional poverty and the marginal locations play important role.展开更多
Root-cause identification plays a vital role in business decision making by providing effective future directions for the organizations.Aspect extraction and sentiment extraction plays a vital role in identifying the ...Root-cause identification plays a vital role in business decision making by providing effective future directions for the organizations.Aspect extraction and sentiment extraction plays a vital role in identifying the rootcauses.This paper proposes the Ensemble based temporal weighting and pareto ranking(ETP)model for Root-cause identification.Aspect extraction is performed based on rules and is followed by opinion identification using the proposed boosted ensemble model.The obtained aspects are validated and ranked using the proposed aspect weighing scheme.Pareto-rule based aspect selection is performed as the final selection mechanism and the results are presented for business decision making.Experiments were performed with the standard five product benchmark dataset.Performances on all five product reviews indicate the effective performance of the proposed model.Comparisons are performed using three standard state-of-the-art models and effectiveness is measured in terms of F-Measure and Detection rates.The results indicate improved performances exhibited by the proposed model with an increase in F-Measure levels at 1%–15%and detection rates at 4%–24%compared to the state-of-the-art models.展开更多
Background: Seven patients at a hospital in Houston, TX, were diagnosed during a two-week period in 2009 with joint space infection of pansusceptible P. aeruginosa following arthroscopic procedures of the knee or shou...Background: Seven patients at a hospital in Houston, TX, were diagnosed during a two-week period in 2009 with joint space infection of pansusceptible P. aeruginosa following arthroscopic procedures of the knee or shoulder. Tosh et al. (2011), who investigated and published the principal report discussing this bacterial outbreak, conclude that its most likely cause was the improper reprocessing of certain reusable, physically-complex, heat-stable arthroscopic instruments used during these arthroscopic procedures. These reusable instruments reportedly remained contaminated with remnant tissue, despite diligent efforts by the hospital to clean their internal structures. This retained bioburden presumably shielded the outbreak’s strain of embedded P. aeruginosa from contact with the pressurized steam, reportedly resulting in ineffective sterilization of these arthroscopic instruments and bacterial transmission. Objectives: First, to clarify which specific sterilization methods, in addition to steam sterilization, Methodist Hospital employed to process its reusable arthroscopic instrumentation at the time of its outbreak, in 2009;second, to evaluate Tosh et al.’s (2011) conclusion that ineffective steam sterilization due to inadequate cleaning was the most likely cause of this hospital’s outbreak;third, to consider whether any other hitherto unrecognized factors could have plausibly contributed to this outbreak;and, fourth, to assess whether any additional recommendations might be warranted to prevent disease transmission following arthroscopic procedures. Methods: The medical literature was reviewed;some of the principles of quality assurance, engineering and a root-cause analysis were employed;and Tosh et al.’s (2011) findings and conclusions were reviewed and compared with those of other published reports that evaluated the risk of disease transmission associated with the steam sterilization of physically-complex, heat-stable, soiled surgical instruments. Results and Conclusion: Reports documenting outbreaks of P. aeruginosa or another vegetative bacterium associated with the steam sterilization of inadequately cleaned surgical or arthroscopic instruments are scant. This finding—coupled with a number of published studies demonstrating the effective steam sterilization of complex instruments contaminated with vegetative bacteria mixed with organic debris, or, in one published series of tests, with resistant bacterial endospores coated with hydraulic fluid—raises for discussion whether Methodist Hospital’s outbreak might have been due to one or more factors other than, or in addition to, that which Tosh et al. (2011) conclude was its most likely cause. An example of such a factor not ruled out by Tosh et al. (2011) findings would be the re-contamination of the implicated arthroscopic instruments after sterilization. The specific methods that Methodist Hospital employed at the time of its outbreak to sterilize some of its arthroscopic instrumentation remain unclear. A number of additional recommendations are provided to prevent disease transmission following arthroscopic procedures.展开更多
Modern industrial systems are usually in large scale,consisting of massive components and variables that form a complex system topology.Owing to the interconnections among devices,a fault may occur and propagate to ex...Modern industrial systems are usually in large scale,consisting of massive components and variables that form a complex system topology.Owing to the interconnections among devices,a fault may occur and propagate to exert widespread influences and lead to a variety of alarms.Obtaining the root causes of alarms is beneficial to the decision supports in making corrective alarm responses.Existing data-driven methods for alarm root cause analysis detect causal relations among alarms mainly based on historical alarm event data.To improve the accuracy,this paper proposes a causal fusion inference method for industrial alarm root cause analysis based on process topology and alarm events.A Granger causality inference method considering process topology is exploited to find out the causal relations among alarms.The topological nodes are used as the inputs of the model,and the alarm causal adjacency matrix between alarm variables is obtained by calculating the likelihood of the topological Hawkes process.The root cause is then obtained from the directed acyclic graph(DAG)among alarm variables.The effectiveness of the proposed method is verified by simulations based on both a numerical example and the Tennessee Eastman process(TEP)model.展开更多
A distributed information network with complex network structure always has a challenge of locating fault root causes.In this paper,we propose a novel root cause analysis(RCA)method by random walk on the weighted faul...A distributed information network with complex network structure always has a challenge of locating fault root causes.In this paper,we propose a novel root cause analysis(RCA)method by random walk on the weighted fault propagation graph.Different from other RCA methods,it mines effective features information related to root causes from offline alarms.Combined with the information,online alarms and graph relationship of network structure are used to construct a weighted graph.Thus,this approach does not require operational experience and can be widely applied in different distributed networks.The proposed method can be used in multiple fault location cases.The experiment results show the proposed approach achieves much better performance with 6%higher precision at least for root fault location,compared with three baseline methods.Besides,we explain how the optimal parameter’s value in the random walk algorithm influences RCA results.展开更多
The paper discusses the framework for a risk-informed root cause analysis process.Such process enables scaling of the analysis performed based on the risk associated with the undesired event or condition,thereby creat...The paper discusses the framework for a risk-informed root cause analysis process.Such process enables scaling of the analysis performed based on the risk associated with the undesired event or condition,thereby creating tiers of analysis where the greater the risk,the more sophisticated the analysis.In a risk-informed root cause analysis process,a situation is normally not analyzed at a level less than what actually occurred.However,a situation may be investigated as though the consequence were greater than actually happened,especially if only slight differences in circumstances could result in a significantly higher consequence.While operational events or safety issues are normally expected to result only with negligible or marginal actual consequences,many of those would actually have certain potential to develop or propagate into catastrophic events.This potential can be expressed qualitatively or quantitatively.Risk-informing of root cause analysis relies on mapping the event or safety issue into a risk matrix which,traditionally,is a two-dimensional probability-consequence matrix.A new concept employed in the risk matrix for root cause analysis is that,while the probability reflects the observed or expected range of values(retaining,thus,its“traditional”meaning),the consequence reflects not only the observed or materialized impact(such as failure of equipment)but,also,its potential to propagate or develop into highly undesirable final state.The paper presents main elements of risk-informed root cause analysis process and discusses qualitative and quantitative aspects and approaches to determination of risk significance of operational events or safety issues.展开更多
Based on the translated version of“The Root Cause of Poverty”by Rutger Bregman on the Ted speech online platform,this research analyzes the application of direct borrowing,imitative translation and creative translat...Based on the translated version of“The Root Cause of Poverty”by Rutger Bregman on the Ted speech online platform,this research analyzes the application of direct borrowing,imitative translation and creative translation in English-Chinese translation.First,we believe the direct borrowing of a ready-made version is most ideal as it reveals the common ground both languages share when translating a source text.Next,it is preferable to imitate an already existing expression as similarity is reader-friendly.However,it is sometimes necessary to adopt creative translation to preserve differences to ensure that the meaning of the original language is accurately transmitted.展开更多
This paper is mainly written to explore how cultural differences and clashes between America and China give rise to mother-daughter discords and conflicts. The paper was conducted based on the definition of culture in...This paper is mainly written to explore how cultural differences and clashes between America and China give rise to mother-daughter discords and conflicts. The paper was conducted based on the definition of culture in order to make clear of cultural conflicts. It is written to analyze the two groups of women immigrants unavoidably encountering the clash between their ancestral culture—Chinese culture and the dominant culture--American culture. Furthermore, the paper demonstrates that the mothers' Chinese roots are the root cause of misunderstandings and conflicts between their American-born daughters and themselves.Besides, the writer analyzes that different standpoints towards education value between mothers and American- born daughters cause their misunderstanding and conflicts. The conclusion is that the diversities between Chinese culture and American culture are the root cause for the mother-daughter discords and conflicts.展开更多
背景心血管疾病(CVD)是腹膜透析(PD)患者死亡的主要原因,而营养不良是PD患者发生CVD及死亡的重要危险因素之一。预后营养指数(PNI)作为一种综合评估患者免疫、炎症和营养状态的指标,因其具有便利性与可靠性等优点,在肿瘤等多种疾病的预...背景心血管疾病(CVD)是腹膜透析(PD)患者死亡的主要原因,而营养不良是PD患者发生CVD及死亡的重要危险因素之一。预后营养指数(PNI)作为一种综合评估患者免疫、炎症和营养状态的指标,因其具有便利性与可靠性等优点,在肿瘤等多种疾病的预后评估中得到了广泛应用。然而,不同时间点的营养状态与PD患者预后之间的关系仍有待进一步探究。目的探讨PD患者首年PNI与CVD死亡之间的关系。方法本研究为多中心、回顾性观察性队列研究,纳入2000-01-01—2019-07-01在南方医科大学南方医院、南方医科大学顺德医院、佛山市第一人民医院以及赣州市人民医院4所中心置管并开始接受PD治疗的1640例PD患者作为研究对象。对患者进行随访,随访截止时间为2021-07-01,终点事件为CVD死亡并记录患者生存时间及具体死亡原因。应用限制性立方条图(RCS)分析PNI与PD患者CVD死亡风险之间的非线性关联;采用Kaplan-Meier法绘制PD患者的生存曲线,绘制PNI预测PD患者CVD死亡的受试者工作特征(ROC)曲线,并根据最佳截断值(cut-off=40.46)将患者分为低PNI组703例与高PNI组937例;采用Log-rank检验和Cox风险回归模型分析探讨PNI对PD患者CVD死亡的影响。结果本研究中位随访时间为30个月,随访期间共148例患者死亡,其中CVD死亡73例(49.32%)。RCS结果表明,PNI与CVD死亡事件呈线性关联(P for Nonlinear=0.655)。ROC曲线显示,PNI预测PD患者CVD死亡的曲线下面积(AUC)为0.717(95%CI=0.659~0.775,P<0.001),灵敏度为74.0%,特异度为58.6%。Kaplan-Meier生存分析结果显示,低PNI组CVD生存率低于高PNI组(χ^(2)=26.685,P<0.001)。多因素Cox风险回归模型分析,校正性别、年龄及CVD病史等混杂因素后,低PNI组仍是CVD死亡的独立预测因素(HR=7.76,95%CI=1.72~35.06,P=0.008),亚组分析结果仍稳健,无明显交互作用。结论PNI降低是PD患者CVD死亡的独立影响因素,PD首年PNI评分在评估PD患者预后有一定的指导意义。展开更多
Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tu...Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tumor were divided into three groups: prevention treatment (PT) group (n=23 cases),post chemotherapy treatment (PCT) group( n=22 cases), Western medicine (WM) group ( n=18 cases). The patients in PT, PCT and WM groups were treated respectively from the fifth day on before chemotherapy and from the first day on after chemotherapy, 18 days in all. The patients in WM group were administered Batilol and Leucogen from the first day on after chemotherapy. Changes of leukocytes and immunoglobulin before and after treatment were observed. Results: 1) Acupoint injection of Astragalus Root injectio could increase the number of leukocytes and immunoglobulin content and its effect was better than that of Western medicine (P<0.05); 2) The effect of PT group was better than that of PCT group in preventing and treating virulent and side effects of chemotherapy (P<0.05). Conclusion: It should be stressed on prevention of malignant tumor by using acupoint injection of Astragalus Root for relieving virulent and side effects of chemotherapy.展开更多
基金Supported by Youth Funding of Sichuan Academy of Soclal Scienccs in 2003(YFSASS03-13)
文摘There are 36 counties affirmed to be aid-poverty-development county in the early 21st century, which distribute around the circumferential mountain of Sichuan Basin, According to the topographic features and the distribution of nationality, these aid-poverty-development counties can be classified into 4 depressed-regions. Study shows that regional poverty performance of 4 depressed-regions not only has many commons in the field of regional economic structure and industry structure, which is far behind the average development performance of Sichuan in the field of economic sum per capita such as GDP, farmer net income per capita as well as retail scale consumer goods, it is also quite different related to infrastructure and social development within 4 depressed-regions. Regional Poverty is chronically resulted in interaction of the multi-factors. Natural condition constraint is the basic factor contributed to regional poverty, policy influences play key role, the poor culture is inherent factor to regional poverty and the marginal locations play important role.
文摘Root-cause identification plays a vital role in business decision making by providing effective future directions for the organizations.Aspect extraction and sentiment extraction plays a vital role in identifying the rootcauses.This paper proposes the Ensemble based temporal weighting and pareto ranking(ETP)model for Root-cause identification.Aspect extraction is performed based on rules and is followed by opinion identification using the proposed boosted ensemble model.The obtained aspects are validated and ranked using the proposed aspect weighing scheme.Pareto-rule based aspect selection is performed as the final selection mechanism and the results are presented for business decision making.Experiments were performed with the standard five product benchmark dataset.Performances on all five product reviews indicate the effective performance of the proposed model.Comparisons are performed using three standard state-of-the-art models and effectiveness is measured in terms of F-Measure and Detection rates.The results indicate improved performances exhibited by the proposed model with an increase in F-Measure levels at 1%–15%and detection rates at 4%–24%compared to the state-of-the-art models.
文摘Background: Seven patients at a hospital in Houston, TX, were diagnosed during a two-week period in 2009 with joint space infection of pansusceptible P. aeruginosa following arthroscopic procedures of the knee or shoulder. Tosh et al. (2011), who investigated and published the principal report discussing this bacterial outbreak, conclude that its most likely cause was the improper reprocessing of certain reusable, physically-complex, heat-stable arthroscopic instruments used during these arthroscopic procedures. These reusable instruments reportedly remained contaminated with remnant tissue, despite diligent efforts by the hospital to clean their internal structures. This retained bioburden presumably shielded the outbreak’s strain of embedded P. aeruginosa from contact with the pressurized steam, reportedly resulting in ineffective sterilization of these arthroscopic instruments and bacterial transmission. Objectives: First, to clarify which specific sterilization methods, in addition to steam sterilization, Methodist Hospital employed to process its reusable arthroscopic instrumentation at the time of its outbreak, in 2009;second, to evaluate Tosh et al.’s (2011) conclusion that ineffective steam sterilization due to inadequate cleaning was the most likely cause of this hospital’s outbreak;third, to consider whether any other hitherto unrecognized factors could have plausibly contributed to this outbreak;and, fourth, to assess whether any additional recommendations might be warranted to prevent disease transmission following arthroscopic procedures. Methods: The medical literature was reviewed;some of the principles of quality assurance, engineering and a root-cause analysis were employed;and Tosh et al.’s (2011) findings and conclusions were reviewed and compared with those of other published reports that evaluated the risk of disease transmission associated with the steam sterilization of physically-complex, heat-stable, soiled surgical instruments. Results and Conclusion: Reports documenting outbreaks of P. aeruginosa or another vegetative bacterium associated with the steam sterilization of inadequately cleaned surgical or arthroscopic instruments are scant. This finding—coupled with a number of published studies demonstrating the effective steam sterilization of complex instruments contaminated with vegetative bacteria mixed with organic debris, or, in one published series of tests, with resistant bacterial endospores coated with hydraulic fluid—raises for discussion whether Methodist Hospital’s outbreak might have been due to one or more factors other than, or in addition to, that which Tosh et al. (2011) conclude was its most likely cause. An example of such a factor not ruled out by Tosh et al. (2011) findings would be the re-contamination of the implicated arthroscopic instruments after sterilization. The specific methods that Methodist Hospital employed at the time of its outbreak to sterilize some of its arthroscopic instrumentation remain unclear. A number of additional recommendations are provided to prevent disease transmission following arthroscopic procedures.
基金supported by the National Natural Science Foundation of China(Nos.61903345 and 61973287)。
文摘Modern industrial systems are usually in large scale,consisting of massive components and variables that form a complex system topology.Owing to the interconnections among devices,a fault may occur and propagate to exert widespread influences and lead to a variety of alarms.Obtaining the root causes of alarms is beneficial to the decision supports in making corrective alarm responses.Existing data-driven methods for alarm root cause analysis detect causal relations among alarms mainly based on historical alarm event data.To improve the accuracy,this paper proposes a causal fusion inference method for industrial alarm root cause analysis based on process topology and alarm events.A Granger causality inference method considering process topology is exploited to find out the causal relations among alarms.The topological nodes are used as the inputs of the model,and the alarm causal adjacency matrix between alarm variables is obtained by calculating the likelihood of the topological Hawkes process.The root cause is then obtained from the directed acyclic graph(DAG)among alarm variables.The effectiveness of the proposed method is verified by simulations based on both a numerical example and the Tennessee Eastman process(TEP)model.
基金supported by ZTE Industry-University-Institute Cooperation Funds under Grant No.HC-CN-20201120009。
文摘A distributed information network with complex network structure always has a challenge of locating fault root causes.In this paper,we propose a novel root cause analysis(RCA)method by random walk on the weighted fault propagation graph.Different from other RCA methods,it mines effective features information related to root causes from offline alarms.Combined with the information,online alarms and graph relationship of network structure are used to construct a weighted graph.Thus,this approach does not require operational experience and can be widely applied in different distributed networks.The proposed method can be used in multiple fault location cases.The experiment results show the proposed approach achieves much better performance with 6%higher precision at least for root fault location,compared with three baseline methods.Besides,we explain how the optimal parameter’s value in the random walk algorithm influences RCA results.
文摘The paper discusses the framework for a risk-informed root cause analysis process.Such process enables scaling of the analysis performed based on the risk associated with the undesired event or condition,thereby creating tiers of analysis where the greater the risk,the more sophisticated the analysis.In a risk-informed root cause analysis process,a situation is normally not analyzed at a level less than what actually occurred.However,a situation may be investigated as though the consequence were greater than actually happened,especially if only slight differences in circumstances could result in a significantly higher consequence.While operational events or safety issues are normally expected to result only with negligible or marginal actual consequences,many of those would actually have certain potential to develop or propagate into catastrophic events.This potential can be expressed qualitatively or quantitatively.Risk-informing of root cause analysis relies on mapping the event or safety issue into a risk matrix which,traditionally,is a two-dimensional probability-consequence matrix.A new concept employed in the risk matrix for root cause analysis is that,while the probability reflects the observed or expected range of values(retaining,thus,its“traditional”meaning),the consequence reflects not only the observed or materialized impact(such as failure of equipment)but,also,its potential to propagate or develop into highly undesirable final state.The paper presents main elements of risk-informed root cause analysis process and discusses qualitative and quantitative aspects and approaches to determination of risk significance of operational events or safety issues.
文摘Based on the translated version of“The Root Cause of Poverty”by Rutger Bregman on the Ted speech online platform,this research analyzes the application of direct borrowing,imitative translation and creative translation in English-Chinese translation.First,we believe the direct borrowing of a ready-made version is most ideal as it reveals the common ground both languages share when translating a source text.Next,it is preferable to imitate an already existing expression as similarity is reader-friendly.However,it is sometimes necessary to adopt creative translation to preserve differences to ensure that the meaning of the original language is accurately transmitted.
文摘This paper is mainly written to explore how cultural differences and clashes between America and China give rise to mother-daughter discords and conflicts. The paper was conducted based on the definition of culture in order to make clear of cultural conflicts. It is written to analyze the two groups of women immigrants unavoidably encountering the clash between their ancestral culture—Chinese culture and the dominant culture--American culture. Furthermore, the paper demonstrates that the mothers' Chinese roots are the root cause of misunderstandings and conflicts between their American-born daughters and themselves.Besides, the writer analyzes that different standpoints towards education value between mothers and American- born daughters cause their misunderstanding and conflicts. The conclusion is that the diversities between Chinese culture and American culture are the root cause for the mother-daughter discords and conflicts.
文摘背景心血管疾病(CVD)是腹膜透析(PD)患者死亡的主要原因,而营养不良是PD患者发生CVD及死亡的重要危险因素之一。预后营养指数(PNI)作为一种综合评估患者免疫、炎症和营养状态的指标,因其具有便利性与可靠性等优点,在肿瘤等多种疾病的预后评估中得到了广泛应用。然而,不同时间点的营养状态与PD患者预后之间的关系仍有待进一步探究。目的探讨PD患者首年PNI与CVD死亡之间的关系。方法本研究为多中心、回顾性观察性队列研究,纳入2000-01-01—2019-07-01在南方医科大学南方医院、南方医科大学顺德医院、佛山市第一人民医院以及赣州市人民医院4所中心置管并开始接受PD治疗的1640例PD患者作为研究对象。对患者进行随访,随访截止时间为2021-07-01,终点事件为CVD死亡并记录患者生存时间及具体死亡原因。应用限制性立方条图(RCS)分析PNI与PD患者CVD死亡风险之间的非线性关联;采用Kaplan-Meier法绘制PD患者的生存曲线,绘制PNI预测PD患者CVD死亡的受试者工作特征(ROC)曲线,并根据最佳截断值(cut-off=40.46)将患者分为低PNI组703例与高PNI组937例;采用Log-rank检验和Cox风险回归模型分析探讨PNI对PD患者CVD死亡的影响。结果本研究中位随访时间为30个月,随访期间共148例患者死亡,其中CVD死亡73例(49.32%)。RCS结果表明,PNI与CVD死亡事件呈线性关联(P for Nonlinear=0.655)。ROC曲线显示,PNI预测PD患者CVD死亡的曲线下面积(AUC)为0.717(95%CI=0.659~0.775,P<0.001),灵敏度为74.0%,特异度为58.6%。Kaplan-Meier生存分析结果显示,低PNI组CVD生存率低于高PNI组(χ^(2)=26.685,P<0.001)。多因素Cox风险回归模型分析,校正性别、年龄及CVD病史等混杂因素后,低PNI组仍是CVD死亡的独立预测因素(HR=7.76,95%CI=1.72~35.06,P=0.008),亚组分析结果仍稳健,无明显交互作用。结论PNI降低是PD患者CVD死亡的独立影响因素,PD首年PNI评分在评估PD患者预后有一定的指导意义。
文摘Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tumor were divided into three groups: prevention treatment (PT) group (n=23 cases),post chemotherapy treatment (PCT) group( n=22 cases), Western medicine (WM) group ( n=18 cases). The patients in PT, PCT and WM groups were treated respectively from the fifth day on before chemotherapy and from the first day on after chemotherapy, 18 days in all. The patients in WM group were administered Batilol and Leucogen from the first day on after chemotherapy. Changes of leukocytes and immunoglobulin before and after treatment were observed. Results: 1) Acupoint injection of Astragalus Root injectio could increase the number of leukocytes and immunoglobulin content and its effect was better than that of Western medicine (P<0.05); 2) The effect of PT group was better than that of PCT group in preventing and treating virulent and side effects of chemotherapy (P<0.05). Conclusion: It should be stressed on prevention of malignant tumor by using acupoint injection of Astragalus Root for relieving virulent and side effects of chemotherapy.
