Research on the Sustainable Utilization of Water Resources of Jinan City

The study on the sustainable utilization of water resources of Jinan city is a research hotspot in the urban sustainable development field.How to use a scientific and rational evaluation index system to analyze the sustainable utilization of water resources of Jinan city and then guide the development and utilization of water resources becomes particularly important.Based on the theory of sustainable development this study introduces the method,basic steps and evaluation indexes of the assessment of the development and utilization of water resources.By systemic analyzing the exploitation and utilization standards of water resources and economy and society in Jinan city,the evaluation and index system of sustainable utilization of water resources in Jinan city can be constructed and index weight can be confirmed,and then,the standard of sustainable utilization of water resources in different years can be analyzed comparably.Thus,the deficiency of lack of reflection of coordination extent in water resources development standard,society and economy in traditional evaluation method is settled efficiently.The paper takes the sustainable utilization of water resources of Qingdao City in 2008 as the standard to compare and assess the water resources utilization in Jinan City.The paper also collects data of water resources in Jinan City from 2001 to 2007.The result indicates that evaluation method is of feasibility and it is effective to the implementation of sustainable utilization strategy water resources in Jinan City.

Selection Method of Production Enterprises by Large Pharmaceutical Commercial Companies Based on AHP

Objective To study the policies of integrating medical resources and centralized drug procurement in China from 2018 to 2020,and to provide a reference for large pharmaceutical commercial companies to select partners.Methods Analytic hierarchy process(AHP)and fuzzy synthesis evaluation method were used to establish the index evaluation system and assign values to each index.Results and Conclusion According to the questionnaire survey data,the weight of each evaluation index was determined,and the evaluation results were obtained by using the fuzzy synthesis evaluation method.The selection of production enterprises by large pharmaceutical commercial companies includes five first-level indicators and 11 second-level indicators.They can provide a favorable reference for the selection of production enterprises by large pharmaceutical commercial companies against the background of complex pharmaceutical industry.

Design,synthesis and biological evaluation of novel non-azole derivatives as potential antifungal agents

A series of 3-substituted quinazolinones,2-substituted quinoxalines and 2-substituted benzopyrans were synthesized and evaluated for their antifungal activity in vitro.The new compounds revealed excellent in vitro antifungal activity with broad spectrum.The structure-activity relationships（SARs） of the derivatives were analyzed.Compound 9A2 exhibits better antifungal activity against 5 tested fungi in vitro than fluconazole,especially against Trichophyton rubrum and Microsporum gypseum.This study provides a series of novel lead compounds for the development of non-azole antifungal agents.