In this paper,the new theory frame and practical methhod for determining all the minimum solutions of Fuzzy matrix equation and transitive closure of Fuzzy relation is described,and it has been carried out on the mier...In this paper,the new theory frame and practical methhod for determining all the minimum solutions of Fuzzy matrix equation and transitive closure of Fuzzy relation is described,and it has been carried out on the miero-computer quickly and accurately.展开更多
A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical...A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical formation design. In order to study the elliptical control strategy and perturbation effects, it is necessary to derive the inverse transformation of the relative state transition matrix based on relative orbit elements. Poisson bracket theory is used to obtain the linear transformations between the two representations: the relative orbit elements and the geocentric orbital frame. In this paper, the details of these transformations are presented.展开更多
Objective:To study the correlation of Claudins6 (CLDN6) gene expression in meningioma tissue with the expression of matrix metalloproteinases (MMPs)/tissue inhibitors of matrix metalloproteinase (TIMPs) and epithelial...Objective:To study the correlation of Claudins6 (CLDN6) gene expression in meningioma tissue with the expression of matrix metalloproteinases (MMPs)/tissue inhibitors of matrix metalloproteinase (TIMPs) and epithelial-mesenchymal transition (EMT) genes.Methods:Meningioma tissue samples that were surgically removed in Yibin First People's Hospital between April 2014 and May 2017 were selected, normal arachnoid tissue samples that were collected from decompressive craniectomy in Yibin First People's Hospital during the same period were selected, and the expression of CLDN6, MMPs/TIMPs and EMT genes in tissues were determined.Results: CLDN6 protein expression in meningioma tissue was significantly lower than that in normal arachnoid tissue;EMMPRIN, MMP2, MMP9, Vimentin and N-cadherin protein expression in meningioma tissue were significantly higher than those in normal arachnoid tissue while TIMP1, TIMP2, E-cadherin andα-catenin protein expression were significantly lower than those in normal arachnoid tissue;EMMPRIN, MMP2, MMP9, Vimentin and N-cadherin protein expression in meningioma tissue with higher CLDN6 expression were significantly lower than those in meningioma tissue with lower CLDN6 expression while TIMP1, TIMP2, E-cadherin andα-catenin protein expression were significantly higher than those in meningioma tissue with lower CLDN6 expression. Conclusion: Lowly expressed CLDN6 gene in meningioma tissue can increase the hydrolysis activity of MMPs, induce epithelial-mesenchymal transition and thus promote the invasive growth of meningioma.展开更多
Objective: To investigate the correlation of annexin A2 expression with epithelial-mesenchymal transition (EMT) and extracellular matrix (ECM) degradation in bile duct carcinoma. Methods: A total of 60 patients with p...Objective: To investigate the correlation of annexin A2 expression with epithelial-mesenchymal transition (EMT) and extracellular matrix (ECM) degradation in bile duct carcinoma. Methods: A total of 60 patients with primary bile duct carcinoma who accepted bile duct carcinoma laparotomy in our hospital between April 2009 and May 2017 were selected. The bile duct carcinoma tissue and adjacent normal tissue were kept during operation and enrolled in bile duct cancer group (n=60) and normal control group (n=60). The protein expression of annexin A2, EMT marker molecules, MMPs subtypes and TIMPs subtypes in two groups of specimens were detected, and Pearson test was used to evaluate the correlation of annexin A2 expression with EMT and ECM degradation in bile duct carcinoma tissue. Results: Annexin A2 expression in bile duct cancer group was higher than that in normal control group;E-cadherin, β-catenin and syndecan-1 protein expression in bile duct cancer group were lower than those in control group whereas P-cadherin and Vimentin protein expression were higher than those in normal control group;MMP-2, MMP-7 and MMP-9 protein expression in bile duct cancer group were higher than those in normal control group whereas TIMP-1 and TIMP-2 protein expression were lower than those in normal control group. Pearson test showed that the annexin A2 expression in bile duct carcinoma was directly correlated with the protein expression of EMT marker molecules, MMPs subtypes and TIMPs subtypes. Conclusion: annexin A2 increases in bile duct carcinoma, and it can regulate EMT and ECM degradation process to affect the disease outcome.展开更多
An element based on the harmonic functions for Performing vibration analysis oflinkages was developed to propose the matrix-transit equations and the kineto-elastrodynamics(KED) different equations. Method and the KED...An element based on the harmonic functions for Performing vibration analysis oflinkages was developed to propose the matrix-transit equations and the kineto-elastrodynamics(KED) different equations. Method and the KED equations was continllous undertaken by themodal superposition approach. The results from those equations include the quasistatic parts andthe dynamic parts. The dynamic parts equaled to the developing parts of the computationaccurations.展开更多
Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoi...Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoil components, which mainly comes from different weaving methods and different braided tow thickness. However, few people have studied the influence of surface morphology of ceramic matrix composites(CMCs) on the development of boundary layer and the resulting flow loss. In this paper, Tex Gen is used to generate different surface morphology structures of ceramic matrix composites(CMCs), and the surface flow characteristics of corresponding CMCs plates are numerically studied. It is found that the slope of the displacement thickness of the woven surface first increases and then decreases in the whole transition interval. Thicker braided tow thickness and denser braiding method will induce earlier flow transition phenomenon and produce greater flow loss;The flow loss on the surface of CMCs plate is mainly composed of the vortex loss in the pit and the boundary layer loss outside the pit, and the boundary layer loss is dominant. The weaving methods has a greater influence on the flow state and flow loss of the boundary layer.展开更多
文摘In this paper,the new theory frame and practical methhod for determining all the minimum solutions of Fuzzy matrix equation and transitive closure of Fuzzy relation is described,and it has been carried out on the miero-computer quickly and accurately.
文摘A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical formation design. In order to study the elliptical control strategy and perturbation effects, it is necessary to derive the inverse transformation of the relative state transition matrix based on relative orbit elements. Poisson bracket theory is used to obtain the linear transformations between the two representations: the relative orbit elements and the geocentric orbital frame. In this paper, the details of these transformations are presented.
文摘Objective:To study the correlation of Claudins6 (CLDN6) gene expression in meningioma tissue with the expression of matrix metalloproteinases (MMPs)/tissue inhibitors of matrix metalloproteinase (TIMPs) and epithelial-mesenchymal transition (EMT) genes.Methods:Meningioma tissue samples that were surgically removed in Yibin First People's Hospital between April 2014 and May 2017 were selected, normal arachnoid tissue samples that were collected from decompressive craniectomy in Yibin First People's Hospital during the same period were selected, and the expression of CLDN6, MMPs/TIMPs and EMT genes in tissues were determined.Results: CLDN6 protein expression in meningioma tissue was significantly lower than that in normal arachnoid tissue;EMMPRIN, MMP2, MMP9, Vimentin and N-cadherin protein expression in meningioma tissue were significantly higher than those in normal arachnoid tissue while TIMP1, TIMP2, E-cadherin andα-catenin protein expression were significantly lower than those in normal arachnoid tissue;EMMPRIN, MMP2, MMP9, Vimentin and N-cadherin protein expression in meningioma tissue with higher CLDN6 expression were significantly lower than those in meningioma tissue with lower CLDN6 expression while TIMP1, TIMP2, E-cadherin andα-catenin protein expression were significantly higher than those in meningioma tissue with lower CLDN6 expression. Conclusion: Lowly expressed CLDN6 gene in meningioma tissue can increase the hydrolysis activity of MMPs, induce epithelial-mesenchymal transition and thus promote the invasive growth of meningioma.
文摘Objective: To investigate the correlation of annexin A2 expression with epithelial-mesenchymal transition (EMT) and extracellular matrix (ECM) degradation in bile duct carcinoma. Methods: A total of 60 patients with primary bile duct carcinoma who accepted bile duct carcinoma laparotomy in our hospital between April 2009 and May 2017 were selected. The bile duct carcinoma tissue and adjacent normal tissue were kept during operation and enrolled in bile duct cancer group (n=60) and normal control group (n=60). The protein expression of annexin A2, EMT marker molecules, MMPs subtypes and TIMPs subtypes in two groups of specimens were detected, and Pearson test was used to evaluate the correlation of annexin A2 expression with EMT and ECM degradation in bile duct carcinoma tissue. Results: Annexin A2 expression in bile duct cancer group was higher than that in normal control group;E-cadherin, β-catenin and syndecan-1 protein expression in bile duct cancer group were lower than those in control group whereas P-cadherin and Vimentin protein expression were higher than those in normal control group;MMP-2, MMP-7 and MMP-9 protein expression in bile duct cancer group were higher than those in normal control group whereas TIMP-1 and TIMP-2 protein expression were lower than those in normal control group. Pearson test showed that the annexin A2 expression in bile duct carcinoma was directly correlated with the protein expression of EMT marker molecules, MMPs subtypes and TIMPs subtypes. Conclusion: annexin A2 increases in bile duct carcinoma, and it can regulate EMT and ECM degradation process to affect the disease outcome.
文摘An element based on the harmonic functions for Performing vibration analysis oflinkages was developed to propose the matrix-transit equations and the kineto-elastrodynamics(KED) different equations. Method and the KED equations was continllous undertaken by themodal superposition approach. The results from those equations include the quasistatic parts andthe dynamic parts. The dynamic parts equaled to the developing parts of the computationaccurations.
基金National Science and Technology Major Project (Y2019-I-0018-0017)。
文摘Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoil components, which mainly comes from different weaving methods and different braided tow thickness. However, few people have studied the influence of surface morphology of ceramic matrix composites(CMCs) on the development of boundary layer and the resulting flow loss. In this paper, Tex Gen is used to generate different surface morphology structures of ceramic matrix composites(CMCs), and the surface flow characteristics of corresponding CMCs plates are numerically studied. It is found that the slope of the displacement thickness of the woven surface first increases and then decreases in the whole transition interval. Thicker braided tow thickness and denser braiding method will induce earlier flow transition phenomenon and produce greater flow loss;The flow loss on the surface of CMCs plate is mainly composed of the vortex loss in the pit and the boundary layer loss outside the pit, and the boundary layer loss is dominant. The weaving methods has a greater influence on the flow state and flow loss of the boundary layer.
