本文以Tcu220c-IUD为对照,测定置MA-IUD妇女月经总量;经血纤溶系统包括组织型纤溶酶原激活剂(t-PA)活性、纤溶酶原(PLG)含量和纤溶活性(Fa);经血抗凝血物质包括抗凝血酶-Ⅲ(AT-Ⅲ)活性、蛋白 C(PC)抗原含量和 PC 活性以及经血凝血因子...本文以Tcu220c-IUD为对照,测定置MA-IUD妇女月经总量;经血纤溶系统包括组织型纤溶酶原激活剂(t-PA)活性、纤溶酶原(PLG)含量和纤溶活性(Fa);经血抗凝血物质包括抗凝血酶-Ⅲ(AT-Ⅲ)活性、蛋白 C(PC)抗原含量和 PC 活性以及经血凝血因子包括因子Ⅶ相关抗原(ⅧR:Ag)和纤维蛋白原(Fg)含量。实验表明 MA-IUD 能使妇女月经量明显减少,其与宫腔局部纤溶活性和抗凝血系统活性下降有关。宫腔局部凝血因子无明显改变,IUD 之孕激素的局部释放对肝脏无影响。展开更多
The Stainless steel ring(SSR),VCu200 and TCu220C were ic randomized comparison for eight years in a cohort of 4,490 subjects covering 16 centres in 9 provinces andmunicipalities.The follow-up rate at the end of the ei...The Stainless steel ring(SSR),VCu200 and TCu220C were ic randomized comparison for eight years in a cohort of 4,490 subjects covering 16 centres in 9 provinces andmunicipalities.The follow-up rate at the end of the eithth year was 90.33%.The cumulative continuation rates were 47.06 per 100 women at the end of foe eighth year for SSR,54.05 for VCu200 and 61.14 for TCu220C.The cumulative pregnancy rates for VCu200and TCu220C were 10.35 and 8.94 per 100 women respectively,significantly lower than24.14 for SSR. There were significant differences in eight-year expulsion rates amongSSR(21.69%),VCu200(13.05%)and TCu220C(7.48%).The removal for bleedingand/or pain was the lowest in SSR;and no signaificant differences were found betweenVCu200 and TCu200C.but foe rate ws getting higher in VCu200 at the end of the eighthyear than in TCu220C.The discontinued use of IUD for desire to become pregnant in rural area was extremely higher than in urban area. The risk of pregnancy and expulsionwas in association with the types of IUD in this study,age at insertion,previous use ofIUD and pregnancy frequency prior to insertion. The risk of pregnancy and expulsion forVCu200 and TCu220C was significantly lower than that for SSR. Failure risks were associated with age at insertion, the types of IUD in this study and pregnancy frequencyprior to insertion,and failure risk in SSR was still higher than in VCu200 and TCu220Cat the end of the eighth year. The study revealed that TCu220C was of good long-termsafety,efficacy,and acceptability.展开更多
文摘The Stainless steel ring(SSR),VCu200 and TCu220C were ic randomized comparison for eight years in a cohort of 4,490 subjects covering 16 centres in 9 provinces andmunicipalities.The follow-up rate at the end of the eithth year was 90.33%.The cumulative continuation rates were 47.06 per 100 women at the end of foe eighth year for SSR,54.05 for VCu200 and 61.14 for TCu220C.The cumulative pregnancy rates for VCu200and TCu220C were 10.35 and 8.94 per 100 women respectively,significantly lower than24.14 for SSR. There were significant differences in eight-year expulsion rates amongSSR(21.69%),VCu200(13.05%)and TCu220C(7.48%).The removal for bleedingand/or pain was the lowest in SSR;and no signaificant differences were found betweenVCu200 and TCu200C.but foe rate ws getting higher in VCu200 at the end of the eighthyear than in TCu220C.The discontinued use of IUD for desire to become pregnant in rural area was extremely higher than in urban area. The risk of pregnancy and expulsionwas in association with the types of IUD in this study,age at insertion,previous use ofIUD and pregnancy frequency prior to insertion. The risk of pregnancy and expulsion forVCu200 and TCu220C was significantly lower than that for SSR. Failure risks were associated with age at insertion, the types of IUD in this study and pregnancy frequencyprior to insertion,and failure risk in SSR was still higher than in VCu200 and TCu220Cat the end of the eighth year. The study revealed that TCu220C was of good long-termsafety,efficacy,and acceptability.
