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基于TF-IDF算法的运营商客户投诉原因研究 被引量:1
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作者 张爱华 孙嘉鸿 《北京邮电大学学报(社会科学版)》 2024年第2期39-49,共11页
针对运营商人工处理客户投诉工单高成本低效率问题,提出了一种基于TF-IDF算法的定量研究方法,旨在高效精准地识别客户投诉原因。选用Jieba分词,导入自定义词典和停用词列表,对运营商客户投诉工单进行关键词抽取,获取各类问题中TF-IDF值... 针对运营商人工处理客户投诉工单高成本低效率问题,提出了一种基于TF-IDF算法的定量研究方法,旨在高效精准地识别客户投诉原因。选用Jieba分词,导入自定义词典和停用词列表,对运营商客户投诉工单进行关键词抽取,获取各类问题中TF-IDF值排名前6的关键词,输出关键词集。提高了关键词抽取的准确性和效率。此外,对比仅对文档集使用TF进行统计和使用TextRank算法的情况,突显了IDF的重要性及算法原理的差异。实验结果表明,光猫、路由器、机顶盒问题广泛存在于各类投诉中。针对这三类问题,为运营商提供了改进产品、服务的相关建议,对运营商集中治理、解决问题具有一定的实用价值。 展开更多
关键词 投诉工单 投诉原因 关键词抽取 tf-idf
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基于TF-IDF和多头注意力Transformer模型的文本情感分析 被引量:7
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作者 高佳希 黄海燕 《华东理工大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第1期129-136,共8页
文本情感分析旨在对带有情感色彩的主观性文本进行分析、处理、归纳和推理,是自然语言处理中一项重要任务。针对现有的计算方法不能充分处理复杂度和混淆度较高的文本数据集的问题,提出了一种基于TF-IDF(Term Frequency-Inverse Documen... 文本情感分析旨在对带有情感色彩的主观性文本进行分析、处理、归纳和推理,是自然语言处理中一项重要任务。针对现有的计算方法不能充分处理复杂度和混淆度较高的文本数据集的问题,提出了一种基于TF-IDF(Term Frequency-Inverse Document Frequency)和多头注意力Transformer模型的文本情感分析模型。在文本预处理阶段,利用TF-IDF算法对影响文本情感倾向较大的词语进行初步筛选,舍去常见的停用词及其他文本所属邻域对文本情感倾向影响较小的专有名词。然后,利用多头注意力Transformer模型编码器进行特征提取,抓取文本内部重要的语义信息,提高模型对语义的分析和泛化能力。该模型在多领域、多类型评论语料库数据集上取得了98.17%的准确率。 展开更多
关键词 文本情感分析 自然语言处理 多头注意力机制 tf-idf算法 Transformer模型
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长三角一体化发展特征与动力探究——基于TF-IDF算法与格兰杰检验
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作者 关硕 赵雪 刘毅 《科技和产业》 2024年第5期40-47,共8页
从政策观念视角出发,深入探讨长三角区域一体化发展进程,有助于洞察区域内生发展动力和经济增长潜力。应用话语制度主义和间断-均衡框架,结合TF-IDF(词频-逆文档频率)算法与格兰杰检验,揭示长三角一体化发展特征与动因。研究发现:建设... 从政策观念视角出发,深入探讨长三角区域一体化发展进程,有助于洞察区域内生发展动力和经济增长潜力。应用话语制度主义和间断-均衡框架,结合TF-IDF(词频-逆文档频率)算法与格兰杰检验,揭示长三角一体化发展特征与动因。研究发现:建设主体对5个发展目标的注意力分配不均衡;在创新共建目标方面,地方主体的注意力变动会引起中央主体的注意力变动;长三角一体化发展呈现小间断大均衡特征,体现“自下而上”的地方主导模式。 展开更多
关键词 长三角一体化 话语制度主义 间断-均衡框架 tf-idf(词频-逆文件频率)算法 格兰杰检验
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Fanlian Huazhuo Formula alleviates high-fat diet-induced nonalcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway 被引量:1
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作者 Meng-Yuan Niu Geng-Ting Dong +9 位作者 Yi Li Qing Luo Liu Cao Xi-Min Wang Qi-Wen Wang Yi-Ting Wang Zhe Zhang Xi-Wen Zhong Wei-Bo Dai Le-Yu Li 《World Journal of Gastroenterology》 SCIE CAS 2024年第30期3584-3608,共25页
BACKGROUND Fanlian Huazhuo Formula(FLHZF)has the functions of invigorating spleen and resolving phlegm,clearing heat and purging turbidity.It has been identified to have therapeutic effects on type 2 diabetes mellitus... BACKGROUND Fanlian Huazhuo Formula(FLHZF)has the functions of invigorating spleen and resolving phlegm,clearing heat and purging turbidity.It has been identified to have therapeutic effects on type 2 diabetes mellitus(T2DM)in clinical application.Non-alcoholic fatty liver disease(NAFLD)is frequently diagnosed in patients with T2DM.However,the therapeutic potential of FLHZF on NAFLD and the underlying mechanisms need further investigation.AIM To elucidate the effects of FLHZF on NAFLD and explore the underlying hepatoprotective mechanisms in vivo and in vitro.METHODS HepG2 cells were treated with free fatty acid for 24 hours to induce lipid accumulation cell model.Subsequently,experiments were conducted with the different concentrations of freeze-dried powder of FLHZF for 24 hours.C57BL/6 mice were fed a high-fat diet for 8-week to establish a mouse model of NAFLD,and then treated with the different concentrations of FLHZF for 10 weeks.RESULTS FLHZF had therapeutic potential against lipid accumulation and abnormal changes in biochemical indicators in vivo and in vitro.Further experiments verified that FLHZF alleviated abnormal lipid metabolism might by reducing oxidative stress,regulating the AMPKα/SREBP-1C signaling pathway,activating autophagy,and inhibiting hepatocyte apoptosis.CONCLUSION FLHZF alleviates abnormal lipid metabolism in NAFLD models by regulating reactive oxygen species,autophagy,apoptosis,and lipid synthesis signaling pathways,indicating its potential for clinical application in NAFLD. 展开更多
关键词 Fanlian Huazhuo formula Nonalcoholic fatty liver disease AUTOPHAGY Apoptosis AMPKα/SREBP-1C signal pathway Oxidative stress
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基于改进TF-IDF和AGLCNN的新闻长文本分类模型
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作者 周宪溪 牟莉 《计算机与现代化》 2024年第8期120-126,共7页
新闻长文本分类是自然语言处理中的一项重要任务,但传统的文本表示方法存在特征稀疏、语义不足等问题。此外,新闻长文本含有大量的冗余信息,并且可能涉及其他主题,以上问题都会导致文本特征提取不全面。为此,本文提出一种基于改进TF-ID... 新闻长文本分类是自然语言处理中的一项重要任务,但传统的文本表示方法存在特征稀疏、语义不足等问题。此外,新闻长文本含有大量的冗余信息,并且可能涉及其他主题,以上问题都会导致文本特征提取不全面。为此,本文提出一种基于改进TF-IDF算法和AGLCNN的新闻长文本分类模型。该模型首先利用特征项在类间与类内分布情况及其位置信息来改进TF-IDF算法,并结合Word2Vec词向量进行文本表示;利用注意力机制突出关键字信息,输入至Bi-LSTM捕获文本上下文特征;接着利用CNN突出新闻主题的显著特征;考虑到新闻长文本中可能存在涉及其他主题信息的句子,引入门控机制对Bi-LSTM和CNN输出特征进行融合,获得最终的文本特征表示;最后,将特征向量输入Softmax层进行新闻分类。在THUCNews数据集和搜狐新闻数据集上进行对比实验,结果表明,所提模型在2个数据集上的召回率分别为0.985和0.976,优于其他分类模型。 展开更多
关键词 文本分类 tf-idf 注意力机制 卷积神经网络 特征项
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A Cauchy integral formula for(p,q)-monogenic functions withα-weight
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作者 GAO Long DU Xiao-jing +1 位作者 LIU Yue XIE Yong-hong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第3期545-553,共9页
Firstly,some properties for(p,q)-monogenic functions withα-weight in Clifford analysis are given.Then,the Cauchy-Pompeiu formula is proved.Finally,the Cauchy integral formula and the Cauchy integral theorem for(p,q)-... Firstly,some properties for(p,q)-monogenic functions withα-weight in Clifford analysis are given.Then,the Cauchy-Pompeiu formula is proved.Finally,the Cauchy integral formula and the Cauchy integral theorem for(p,q)-monogenic functions withα-weight are given. 展开更多
关键词 (p q)-monogenic functions with-weight Cauchy-Pompeiu formula Cauchy integral formula Cauchy integral theorem
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Trace formula of the integro-differential operator on a quantum graph
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作者 WEI Li-xiao YANG Chuan-fu 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第2期311-318,共8页
In this paper we study the eigenvalue problem for integro-differential operators on a lasso graph.The trace formula of the operator is established by applying the residual technique in complex analysis.
关键词 integro-differential operators EIGENVALUE trace formula
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基于改进的TF-IDF标签权重算法的电商用户画像构建
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作者 白雨珂 卢胜男 《信息技术与信息化》 2024年第8期48-51,共4页
在电商环境中,用户画像构建是为了更好地理解和满足用户需求而进行的重要任务。传统的TF-IDF标签权重计算方法无法很好地对标签权重进行调整,为了解决这一问题,提出基于TF-IDF算法的改进方法,旨在提高用户画像的准确性和个性化程度。融... 在电商环境中,用户画像构建是为了更好地理解和满足用户需求而进行的重要任务。传统的TF-IDF标签权重计算方法无法很好地对标签权重进行调整,为了解决这一问题,提出基于TF-IDF算法的改进方法,旨在提高用户画像的准确性和个性化程度。融合相关系数矩阵,对相关性强的标签进行适当降权操作。不同类型的行为对标签信息产生不同的权重,并且标签的权重可能会随着时间的推移而衰减。因此,采用拟合记忆遗忘曲线模拟得到的兴趣遗忘曲线,对用户画像权重进行调优操作。实验结果表明,使用所提出的改进的TF-IDF算法构建用户画像的效果得到显著的提升。 展开更多
关键词 电商 相关系数 标签权重 用户画像 tf-idf算法
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Improved nuclear mass formula with an additional term from the Fermi gas model
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作者 Xiao-Yu Xu Li Deng +3 位作者 Ai-Xi Chen Hang Yang Amir Jalili Han-Kui Wang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第5期131-138,共8页
Nuclear mass is a fundamental property of nuclear physics and a necessary input in nuclear astrophysics.Owing to the complexity of atomic nuclei and nonperturbative strong interactions,conventional physical models can... Nuclear mass is a fundamental property of nuclear physics and a necessary input in nuclear astrophysics.Owing to the complexity of atomic nuclei and nonperturbative strong interactions,conventional physical models cannot completely describe nuclear binding energies.In this study,the mass formula was improved by considering an additional term from the Fermi gas model.All nuclear masses in the Atomic Mass Evaluation Database were reproduced with a root-mean-square deviation(RMSD)of -1.86 MeV(1.92 MeV).The new mass formula exhibits good performance in the neutron-rich nuclear region.The RMSD decreases to 0.393 MeV when the ratio of the neutron number to the proton number is≥1.6. 展开更多
关键词 Nuclear mass formula Neutron-rich nuclei Fermi-gas model
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Analytical Solution and Simplified Formula for Added Mass of Horizontal and Vertical Motions of Truncated Cylinders Under Earthquake Action
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作者 WANG Pi-guang LYU Si-yu +2 位作者 QU Yang ZHAO Mi DU Xiu-li 《China Ocean Engineering》 SCIE EI CSCD 2024年第1期54-67,共14页
This paper investigates the hydrodynamic characteristics of floating truncated cylinders undergoing horizontal and vertical motions due to earthquake excitations in the finite water depth.The governing equation of the... This paper investigates the hydrodynamic characteristics of floating truncated cylinders undergoing horizontal and vertical motions due to earthquake excitations in the finite water depth.The governing equation of the hydrodynamic pressure acting on the cylinder is derived based on the radiation theory with the inviscid and incompressible assumptions.The governing equation is solved by using the method of separating variables and analytical solutions are obtained by assigning reasonable boundary conditions.The analytical result is validated by a numerical model using the exact artificial boundary simulation of the infinite water.The main variation and distribution characteristics of the hydrodynamic pressure acting on the side and bottom of the cylinder are analyzed for different combinations of wide-height and immersion ratios.The added mass coefficient of the cylinder is calculated by integrating the hydrodynamic pressure and simplified formulas are proposed for engineering applications.The calculation results show that the simplified formulas are in good agreement with the analytical solutions. 展开更多
关键词 EARTHQUAKE hydrodynamic pressure truncated cylinder added mass simplified formula
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Examining the Use of Scott’s Formula and Link Expiration Time Metric for Vehicular Clustering
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作者 Fady Samann Shavan Askar 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期2421-2444,共24页
Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms.K-clustering algorithms are sim... Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms.K-clustering algorithms are simplistic,with fast performance and relative accuracy.However,their implementation depends on the initial selection of clusters number(K),the initial clusters’centers,and the clustering metric.This paper investigated using Scott’s histogram formula to estimate the K number and the Link Expiration Time(LET)as a clustering metric.Realistic traffic flows were considered for three maps,namely Highway,Traffic Light junction,and Roundabout junction,to study the effect of road layout on estimating the K number.A fast version of the PAM algorithm was used for clustering with a modification to reduce time complexity.The Affinity propagation algorithm sets the baseline for the estimated K number,and the Medoid Silhouette method is used to quantify the clustering.OMNET++,Veins,and SUMO were used to simulate the traffic,while the related algorithms were implemented in Python.The Scott’s formula estimation of the K number only matched the baseline when the road layout was simple.Moreover,the clustering algorithm required one iteration on average to converge when used with LET. 展开更多
关键词 CLUSTERING vehicular network Scott’s formula FastPAM
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Modified Sadowski formula-based model for the slope shape amplification effect under multistage slope blasting vibration
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作者 Xiaogang Wu Mingyang Wang +2 位作者 Hao Lu Yongjun Zhang Wen Nie 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第5期631-641,共11页
Blasting operations,which are crucial to open-pit mine production due to their simplicity and efficiency,require precise control through accurate vibration velocity calculations.The conventional Sadowski formula mainl... Blasting operations,which are crucial to open-pit mine production due to their simplicity and efficiency,require precise control through accurate vibration velocity calculations.The conventional Sadowski formula mainly focuses on blast center distance but neglects the amplification effect of blasting vibration waves by terraced terrain,from which the calculated blasting vibration velocities are smaller than the actual values,affecting the safety of the project.To address this issue,our model introduces the influences of slope and time into Sadowski formula to measure safety through blast vibration displacement.In the northern section of the open-pit quartz mine in Jinchang City,Gansu Province,China,the data of a continuous blasting slope project are referred to.Our findings reveal a noticeable vibration amplification effect during blasting when a multi-stage slope platform undergoes a sudden cross-sectional change near the upper overhanging surface.The amplification vibration coefficient increases with height,while vibration waves within rocks decrease from bottom to top.Conversely,platforms without distinct crosssectional changes exhibit no pronounced amplification during blasting.In addition,the vibration intensity decreases with distance as the rock height difference change propagates.The results obtained by the proposed blast vibration displacement equation incorporating slope shape influence closely agree with real-world scenarios.According to Pearson correlation coefficient(PPMCC)analysis,the average accuracy rate of our model is 88.84%,which exceeds the conventional Sadowski formula(46.92%). 展开更多
关键词 Multistage slope Slope shape influence factor Continuous blasting Sadowski formula Amplification effect
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Jianpi Qinghua Formula Alleviates Diabetic Myocardial Injury Through Inhibiting JunB/c-Fos Expression
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作者 Lin WANG Qing-guang CHEN Hao LU 《Current Medical Science》 SCIE CAS 2024年第1期144-155,共12页
Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,m... Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,myocardial hypertrophy,and impaired left ventricular diastolic function.While the clinical utility of the Jianpi Qinghua(JPQH)formula has been established in treating diabetes and insulin resistance,its potential efficacy in alleviating diabetic cardiomyopathy remains uncertain.This study aims to investigate the impact and underlying molecular mechanisms of the JPQH formula(JPQHF)in ameliorating myocardial injury in nonobese diabetic rats,specifically focusing on apoptosis and inflammation.Methods Wistar rats were assigned as the normal control group(CON),while Goto-Kakizaki(GK)rats were randomly divided into three groups:DM,DM treated with the JPQHF,and DM treated with metformin(MET).Following a 4-week treatment regimen,various biochemical markers related to glucose metabolism,cardiac function,cardiac morphology,and myocardial ultrastructure in GK rats were assessed.RNA sequencing was utilized to analyze differential gene expression and identify potential therapeutic targets.In vitro experiments involved high glucose to induce apoptosis and inflammation in H9c2 cells.Cell viability was evaluated using CCK-8 assay,apoptosis was monitored via flow cytometry,and the production of inflammatory cytokines was measured using quantitative real-time PCR(qPCR)and ELISA.Protein expression levels were determined by Western blotting analysis.The investigation also incorporated the use of MAPK inhibitors to further elucidate the mechanism at both the transcriptional and protein levels.Results The JPQHF group exhibited significant reductions in interventricular septal thickness at end-systole(IVSs)and left ventricular internal diameter at end-systole and end-diastole(LVIDs and LVIDd).JPQHF effectively suppressed high glucose-induced activation of IL-1βand caspase 3 in cardiomyocytes.Furthermore,JPQHF downregulated the expression of myocardial JunB/c-Fos,which was upregulated in both diabetic rats and high glucose-treated H9c2 cells.Conclusion The JPQH formula holds promise in mitigating diabetic myocardial apoptosis and inflammation in cardiomyocytes by inhibiting JunB/c-Fos expression through suppressing the MAPK(p38 and ERK1/2)pathway. 展开更多
关键词 Jianpi Qinghua formula diabetic cardiomyopathy AP-1 transcription factor apoptosis inflammation
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Antidepressant effects of Peiyuan Jieyu formula in a mouse model of chronic stress in conjunction with lipopolysaccharide-induced depression
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作者 Qin Tang Yu Li +3 位作者 Tao Yang Xiaoxu Fan Lina Li Hongsheng Chang 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第1期111-119,共9页
Objective:To explore the mechanism of the Peiyuan Jieyu formula in treating depression by assessing its impact on a lipopolysaccharide-induced(LPS-induced)depression mouse model.Methods:We created a mouse model of dep... Objective:To explore the mechanism of the Peiyuan Jieyu formula in treating depression by assessing its impact on a lipopolysaccharide-induced(LPS-induced)depression mouse model.Methods:We created a mouse model of depression by exposing mice that had previously received chronic stress to intraperitoneal LPS injections.The mice were divided into the following groups:control,model,fluoxetine,Tiansi Yin,Sini powder,and low-,medium-,and high-dose Peiyuan Jieyu formula groups.Forced swim and tail suspension tests were used to assess the efficacy of the depression(despair)model,and weight gain rates were also measured.Furthermore,serum levels of various depression and inflammation-associated molecules,including tumor necrosis factor-a(TNF-a),interferon-γ(IFN-γ),tryptophan,5-hydroxytryptamine,kynurenine(KYN),and kynurenic acid(KA)were assessed.Furthermore,the expression levels of ionic calcium-binding adaptor molecule-1(IBA-1)and indoleamine 2,3-dioxygenase(IDO)mRNA in hippocampal microglia were measured.Results:The model group displayed greater despair-associated immobility,which was shortened in response to various doses of Peiyuan Jieyu formula.Furthermore,formula administration significantly reduced serum TNF-a levels and hippocampal IDO mRNA expression.The high formula dose also reduced IFN-γand IBA-1 levels,the latter was also decreased in response to the medium formula dose.However,the low formula dose reduced serum KYN level and KYN/tryptophan(TRP)and KYN/KA ratios.Conclusion:The Peiyuan Jieyu formula holds immense potential in treating depression in a mouse model,potentially inhibiting inflammation and improving TRP-KYN metabolic disorders. 展开更多
关键词 Peiyuan Jieyu formula DEPRESSION Chronic stress LIPOPOLYSACCHARIDE Inflammation Tryptophan pathway
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Gastrointestinal tolerability of organic infant formula compared to traditional infant formula: A systematic review
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作者 Mohammed Al-Beltagi Nermin Kamal Saeed +2 位作者 Adel Salah Bediwy Reem Elbeltagi Mohamed Basiony Hamza 《World Journal of Clinical Pediatrics》 2024年第1期125-140,共16页
BACKGROUND Infants'nutrition significantly influences their growth,development,and overall well-being.With the increasing demand for organic infant formula driven by the perception of health benefits and growing a... BACKGROUND Infants'nutrition significantly influences their growth,development,and overall well-being.With the increasing demand for organic infant formula driven by the perception of health benefits and growing awareness of natural feeding options,it is crucial to conduct a comparative analysis of the gastrointestinal tolerability between organic and traditional infant formulas.AIM To provide a concise and precise analysis of the gastrointestinal tolerability of organic infant formula compared to traditional infant formula.Due to limited direct comparisons,the review synthesizes available literature on each formula type,presenting insights into their potential effects on infants'digestive health.METHODS An extensive literature search was conducted,compiling studies on organic and traditional infant formulas,their compositions,and reported effects on gastrointestinal tolerability.We searched academic databases such as PubMed and Google Scholar and specialized nutrition,paediatrics,and infant health journals using relevant keywords till October 1,2023.RESULTS Although specific comparative studies are scarce and formula heterogeneity is a significant limitation,this systematic review provides an in-depth understanding of organic infant formulas'composition and potential benefits.While scientific evidence directly comparing gastrointestinal tolerability is limited,organic formulas strive to use carefully selected organic ingredients to imitate breast milk composition.Potential benefits include improved lipid profiles,higher methionine content,and decreased antibiotic-resistant bacteria levels.Understanding the gastrointestinal tolerability of organic and traditional infant formulas is crucial for parents and healthcare providers to make informed decisions.CONCLUSION Despite limitations in direct comparisons,this systematic review provides insights into the composition and potential benefits of organic infant formulas.It emphasizes the need for further research to elucidate their gastrointestinal effects comprehensively. 展开更多
关键词 Organic infant formula Traditional infant formula Gastrointestinal tolerability formula ingredients Digestive health Infant nutrition Organic farming
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Evaluation of the famous classic formula Sanhua decoction based on network pharmacology and multi-component quantitative analysis
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作者 Xin Zhang Wan-Cui Wang +6 位作者 Jin-Kui Zhang Wei-Mei Zhang Peng-Wang Wang Peng-Cheng Lin Yong-Chang Lu Xia Li Wen-Yuan Gao 《Traditional Medicine Research》 2024年第1期1-13,共13页
Background:Sanhua decoction has significant effects in the treatment of stroke.The study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal... Background:Sanhua decoction has significant effects in the treatment of stroke.The study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal pieces and the substance benchmark.Methods:Network pharmacology was employed to investigate the potential active components and molecular mechanisms of Sanhua decoction in the treatment of stroke.15 batches of Sanhua decoction lyophilized powder were prepared using traditional formulas and subjected to high-performance liquid chromatography analysis to generate fingerprints of the Sanhua decoction substance benchmarks.Then,a multi-component quantitative analysis method was established,allowing for the simultaneous determination of ten components,to study the transfer of quantity values between pieces and substance benchmarks.Results:60 active ingredients were screened from Sanhua decoction by network pharmacology,of which gallic acid,magnolol honokiol,physcion,and aloe-emodin may have a greater effect than other active components.63 key targets and 134 pathways were predicted as the potential mechanism of Sanhua decoction in treating stroke.The fingerprint similarity of the Sanhua decoction substance benchmarks was found to be good among the 15 batches,confirming the 19 common peaks.The content of the 10 components was basically consistent.The components’transfer rates were within 30%of their respective means.Conclusions:This study provided a comprehensive and reliable strategy for the quality evaluation of Sanhua decoction substance benchmarks and held significant importance in improving its application value. 展开更多
关键词 Sanhua decoction classic famous formula HPLC fingerprinting value transfer network pharmacology
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Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure
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作者 Ji-Jie Xu Jian Dai +3 位作者 Qi-Hai Xie Pei-Chao Du Cha Li Hua Zhou 《World Journal of Clinical Cases》 SCIE 2024年第17期3027-3034,共8页
BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically ineffective.The optimization of treatments for this disease needs to be explored and analyzed.AIM To analyze the effect of using Luhong F... BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically ineffective.The optimization of treatments for this disease needs to be explored and analyzed.AIM To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function(CPF)and prognosis.METHODS In total,160 patients with CHF admitted between June 2022 and June 2023 were selected,including 75 receiving perindopril(control group)and 85 receiving Luhong Formula(research group).We conducted comparative analyses on the curative effects of traditional Chinese medicine(TCM)syndromes and cardiac function,CPF[oxygen consumption at the anaerobic threshold(VO2 AT)and at peak exercise(peak VO2)],echocardiographic indexes[left atrial volume index(LAVI),left ventricular muscle mass index(LVMI),left ventricular ejection fraction(LVEF)],and prognosis[major adverse cardiovascular events(MACEs)at 6 months follow-up].RESULTS The research group showed markedly higher curative effects of TCM syndromes and cardiac function than the control group.In addition,post-treatment VO2 AT,peak VO2,LVMI and LVEF in the research group were significantly higher,whereas LAVI was significantly lower,than those of the control group.Furthermore,fewer patients in the research group developed MACEs at the 6-month follow-up.CONCLUSION Luhong Formula is more therapeutically effective than perindopril for the cardiac rehabilitation of patients with CHF,specifically in enhancing CPF and prognosis. 展开更多
关键词 Luhong formula Chronic heart failure Cardiopulmonary function Cardiac rehabilitation PROGNOSIS
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Optimal traditional Chinese medicine formulas in treating ulcerative colitis:Choose one or take it all?
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作者 Yan Zeng Jun-Wen Zhang Jian Yang 《World Journal of Clinical Cases》 SCIE 2024年第32期6570-6574,共5页
Ulcerative colitis(UC)is a chronic inflammatory bowel disease that presents significant treatment challenges due to its complexity,especially in terms of the various side effects that traditional medications may bring... Ulcerative colitis(UC)is a chronic inflammatory bowel disease that presents significant treatment challenges due to its complexity,especially in terms of the various side effects that traditional medications may bring during the chronic course of the disease.Traditional Chinese medicine(TCM)has emerged as a promising complementary therapy for UC.Based on the latest research,our editorial explored the current issues and potential essential research directions for TCM in treating UC.We anticipate that future high-quality research will pave the way for the optimization of TCM formulas for UC and their broader global application. 展开更多
关键词 Traditional Chinese medicine Ulcerative colitis Inflammatory bowel disease formula Treatment
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Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach
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作者 Xia-Jie Quan Hao Liang +5 位作者 Yong-Hong Tang Li Jiang Xiong-Ying Ji Feng-Ying Zhang Ping Zhang Bo Ouyang 《Traditional Medicine Research》 2025年第2期16-29,共14页
Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of treatment.Nevertheless,the specific mechanism of action of SXLJF remains unclear.Methods:The mou... Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of treatment.Nevertheless,the specific mechanism of action of SXLJF remains unclear.Methods:The mouse model of insomnia was established by intraperitoneal injection of para-chlorophenylalanine.Forty-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive days.The open field test and pentobarbital-induced sleeping test were conducted.LC-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating insomnia.Finally,key targets were validated using RT-qPCR.Results:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep duration.Metabolomics and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of SXLJF.Specifically,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,respectively.RT-qPCR results supported the role of TH in the mechanism of SXLJF in treating insomnia.Conclusion:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia. 展开更多
关键词 Shangxia Liangji formula INSOMNIA metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism
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Study of the Lift Force Induced by An Interceptor on A High-Speed Mono-Hull:The Affecting Factors and Estimation Formula
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作者 DENG Rui HU Yu-xiao +3 位作者 HUANG Si-chong SONG Zhi-jie WANG Shi-gang WU Tie-cheng 《China Ocean Engineering》 SCIE EI CSCD 2024年第4期557-571,共15页
To find a better way to estimate the lift force induced by an interceptor on a high-speed mono-hull ship,a series of high-speed mono-hull ship models are designed and investigated under different conditions.Different ... To find a better way to estimate the lift force induced by an interceptor on a high-speed mono-hull ship,a series of high-speed mono-hull ship models are designed and investigated under different conditions.Different lift forces are obtained by numerical calculations and validated by a model test in a towing tank.The factors that influence the force are the interceptor height,velocity,draft,and deadrise angle.The relationship between each factor and the induced lift force is investigated and obtained.We found that the induced lift mainly depends on the interceptor height and advancing velocity,and is proportional to the square of the interceptor height and velocity.The results also showed that the effects of the draft and deadrise angle are relatively less important,and the relationship between the induced lift and these two factors is generally linear.Based on the results,a formula including the combined effect of all factors used to estimate the lift force induced by the interceptor is developed based on systematic analysis.The proposed formula could be used to estimate the lift force induced by interceptors,especially under high-speed condition. 展开更多
关键词 high-speed mono-hull ship INTERCEPTOR lift force formula lift force towing tank test computational fluid dynamics
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