Under the condition of steady state, the pressure drop of coolant is mainly caused by friction along the cable. In the CICC (cable-in-conduit-conductor), helium flow within the conductor consists of two parallel inter...Under the condition of steady state, the pressure drop of coolant is mainly caused by friction along the cable. In the CICC (cable-in-conduit-conductor), helium flow within the conductor consists of two parallel interconnected tubes. The velocity distribution has some differece between the central channel and conductor space. The region of Reynolds number is from 103 to 106. This paper describes the calculation of pressure drop of HT-7U CICC at various mass flows. It is assumed that the coolant flows in two parallel, rough tubes during the calculation.展开更多
Previous research revealed the positive activity of matrix metalloproteinase 7(MMP7) on migration and myelin regeneration of Schwa nn cells(SCs). However, understanding of the molecular changes and biological activiti...Previous research revealed the positive activity of matrix metalloproteinase 7(MMP7) on migration and myelin regeneration of Schwa nn cells(SCs). However, understanding of the molecular changes and biological activities induced by increased amounts of MMP7 in SCs remains limited. To better understand the underlying molecular events, primary SCs were isolated from the sciatic nerve stump of newborn rats and cultured with 10 nM human MMP7 for 24 hours. The results of genetic testing were analyzed at a relatively relaxed threshold value(fold change ≥ 1.5 and P-value < 0.05). Upon MMP7 exposure, 149 genes were found to be upregulated in SCs, whereas 133 genes were downregulated. Gene Ontology analysis suggested that many differentially expressed molecules were related to cellular processes, single-organism processes, and metabolic processes. Kyoto Enrichment of Genes and Genomes pathway analysis further indicated the critical involvement of cell signaling and metabolism in MMP7-induced molecular regulation of SCs. Results of Ingenuity Pathway Analysis(IPA) also revealed that MMP7 regulates biological processes, molecular functions, cellular components, diseases and functions, biosynthesis, material metabolism, cell movement, and axon guidance. The outcomes of further analysis will deepen our comprehension of MMP7-induced biological changes in SCs. This study was approved by the Laboratory Animal Ethics Committee of Nantong University, China(approval No. 20190225-004) on February 27, 2019.展开更多
TSARG7 is a novel member of the acyltransferase family since its sequence possesses the highly conserved phosphate acyltransferase （PlsC） domain existing in all acyltransferase-like proteins. The porcine TSARG7 had ...TSARG7 is a novel member of the acyltransferase family since its sequence possesses the highly conserved phosphate acyltransferase （PlsC） domain existing in all acyltransferase-like proteins. The porcine TSARG7 had been identified by cloning in silico but had not been confirmed experimentally. The full-length mRNA of porcine TSARG7 gene was sequenced and two splice variants were discovered. The full-length cDNA of TSARG7 variant 1 was 2 513 bp and variant 2 was 2 634 bp. The putative porcine TSARG7 proteins, which were located in the cytoplasm, encoded 458 and 456 amino acids, respectively. Real-time PCR analysis showed that TSARG7 gene was expressed in various tissues, but at different levels. The expression levels of this gene were higher in the skeletal muscle, heart, and testis than that in other tissues, suggesting that the TSARG7 gene played a role in procine skeletal muscle, heart, and testis functions.展开更多
The HT-7U super-conducting tokamak is a full super-conducting magnetically confined fusion device, It mainly consists of super-conducting toroidal field (TF) coils and super conducting poloidal field (PF) coils. This...The HT-7U super-conducting tokamak is a full super-conducting magnetically confined fusion device, It mainly consists of super-conducting toroidal field (TF) coils and super conducting poloidal field (PF) coils. This paper describes the distribution of magnetic field, ripple and electromagnetic loads of TF system, some results are necessary to analyze and calculate the stresses and deformation on TF system by a finite element method. Meanwhile, in this paper, the main scope of the calculation is carried out for the case of constant magnetic field on conductor of the TF coil winding in order to provide electromagnet parameters for the quench analysis of Cable-in-Conduit Conductor (CICC) of TF system in HT-7U.展开更多
The vacuum vessel of the HT-7U superconducting Tokamak is designed as an allmetal welded double-wall structure with a number of radial and vertical ports. With characteristicsof ultrahigh vacuum and thin shell, the an...The vacuum vessel of the HT-7U superconducting Tokamak is designed as an allmetal welded double-wall structure with a number of radial and vertical ports. With characteristicsof ultrahigh vacuum and thin shell, the analysis on stability is very important to the design. Toachieve a successful final design, a threedimension buckling model has been performed using thefinite element program CoSMOS/M2.0. For all the cases having been considered, a 1/16 segmentof the whole toric shell are used to calculate the linear critical buckling load (Pc.,,) under auniform and nonwhform external pressure. As expected, the structure has a good capability ofwithstanding the applied loads.展开更多
BACKGROUND The clinical manifestations of trisomy 7 mosaicism are diverse and nonspecific,so prenatal diagnosis is very difficult.CASE SUMMARY Two pregnant women with abnormal prenatal screening results were included....BACKGROUND The clinical manifestations of trisomy 7 mosaicism are diverse and nonspecific,so prenatal diagnosis is very difficult.CASE SUMMARY Two pregnant women with abnormal prenatal screening results were included.One was a 22-year-old woman(G1P0).At 31st week of gestation,ultrasound revealed that the posterior horn of the left lateral ventricle was 10 mm and the right renal pelvis had a separation of 7 mm.The other pregnant woman was 33 years old(G2P1L1A0),and her fetus was found to have a cardiac malformation at the 24th week of gestation.Copy number variation sequencing,whole-exome sequencing and karyotype analysis were carried out after amniocentesis,and both fetuses were diagnosed with trisomy 7 mosaicism.After parental counseling,one woman continued the pregnancy,and the other woman terminated the pregnancy.CONCLUSION In trisomy 7 mosaicism,the low proportion of trisomy does not lead to abortion,but can result in abnormal fetal development,which can be detected via ultrasound.Therefore,clinicians need to pay more attention to various aspects of fetal growth and development,combining with imaging,cellular,molecular genetics and other methods to perform comprehensive evaluations of fetuses to provide more reliable genetic counseling for pregnant women.展开更多
In this study, full-length CDS sequence of IGFBP-7 gene was cloned from Liangshan semi-fine wool sheep with RT-PCR method and analyzed with bioinformatics methods. The results showed that the full-length CDS sequence ...In this study, full-length CDS sequence of IGFBP-7 gene was cloned from Liangshan semi-fine wool sheep with RT-PCR method and analyzed with bioinformatics methods. The results showed that the full-length CDS sequence of IGFBP-7 gene in Liangshan semi-fine wool sheep was 846 bp in length, encoding 282 amino acids. The CDS sequence shared 99%, 95% and 90% homology with bovine, human and rat, respectively; the amino acid sequence shared 98%, 93% and 89%, respectively. The GenBank accession number was FJ589640.1. The amino acid molecular weight of IGFBP-7 was 29.0 kD, and the theoretical isoelec- tric point （pl） was 8.25. The result of phylogenetic analysis showed that IGFBP-7 gone in Liangshan semi-fine wool sheep exhibited close phylogenetic relationships with bovine, goat and other mammals, and distant phylogenetic relationships with Danio rerio and Haliotis diversicolor. IGFBP-7 gene had uniformly distributed hy- drophobic and hydrophilic regions, harboring one signal peptide, two transmembrane regions, 16 phosphorylation sites, four N-glycosylation sites and one O-glyco- sylation site. The result of secondary structure analysis showed that the random coil, or-helix and β-sheet regions accounted for 64.89%, 19.86% and 15.25%, respectively. The result of tertiary structure analysis showed that IGFBP-7 harbors an IGFBP_N domain and an Ig-like domain. This study provided scientific basis for further investigating the function of IGFBP-7 gene in sheep.展开更多
The displacement, velocity and acceleration analysis of the general spatial 7R mechanism is discussed in this paper, fused on the method proposed in Ref. [2], an input-output algebra equation of the 16th degree in the...The displacement, velocity and acceleration analysis of the general spatial 7R mechanism is discussed in this paper, fused on the method proposed in Ref. [2], an input-output algebra equation of the 16th degree in the tan-half-angle of the output angular displacement is derived. The derivation process and computation are considerably simple. A program written in Allanguage is used to derive the coefficients of displacement equations: therefore the amount of manual work is greatly decreased. The results are verified by a numerical example. The researches of this paper and Ref. [5]found a base for establishing an expert system of spatial mechanism analysis in the future.展开更多
Human papillomavirus 16 (HPV-16) is a major high-risk type causing cervical cancer. The E6 and E7 genes in HPV-16 are the major virulent genes in HPV, and we wanted to investigate the polymorphism of E6 and E7 genes o...Human papillomavirus 16 (HPV-16) is a major high-risk type causing cervical cancer. The E6 and E7 genes in HPV-16 are the major virulent genes in HPV, and we wanted to investigate the polymorphism of E6 and E7 genes of HPV-16 originated from Jingjiang, Jiangsu province. In research, HPV-16 sample was collected, and the E6 and E7 genes fragments were amplified by PCR assay. The sequences of E6 and E7 genes were used for phylogenetic analysis by Mega 5.0 software. By comparison, the major mutations of E6 gene were T178G (41.67%) and G658A (17%), as well as C58G, T61A and G188C (14%), T61C and C656A (11%). The mutation of E7 gene was mainly C491A and T935A (23%);G514C, G937C and G519C (11%). The 68 nucleotide site deficiency (69.4%) of E6 and 535 nucleotide site deficiency (23%) of E7 were dominant. In our study, we did not find the relevance between the E6 and E7 genes mutations and pathologic severity. But we think the E6 and E7 genes mutation of HPV-16 might affect vaccine prevention and treatment effect.展开更多
Objective:To analyze the structural features of human P2X7R protein,meanwhile homology,protein-protein interaction,and cell epitope were predicted to provide theoretical basis for the diagnosis and treatment of relate...Objective:To analyze the structural features of human P2X7R protein,meanwhile homology,protein-protein interaction,and cell epitope were predicted to provide theoretical basis for the diagnosis and treatment of related diseases.Methods:Human P2X7R protein was analyzed and predicted by ProtParam、TMHMM、ProtScale and SignalP 5.0 Server et al.Results:Human P2X7R protein is composed of 595 amino acids,the molecular formula is C 3077 H 4749 N 835 O 871 S 40,with the theoretical isoelectric point PI of 8.62,the instability coefficient is 46.07,the total average hydrophilicity is-0.317,and the protein is an hydrophilic protein instead of secreted protein,no any signal peptide,but transmembrane region is contained,which belong to transmembrane protein.There are 157αhelices and 288 random coils in the secondary structure of human P2X7R protein,accounting for 26.39%and 48.40%of all amino acids,The coverage rate of the three-level structure prediction results is 100%,and the sequence consistency is 80.34%,and the ramachandran plot show that the predicted structure is relatively stability.The interaction of proteins show that there are a variety of proteins interacting with human P2X7R,and P2X7R was closely related to inflammation;this protein had many B and T cell epitopes,which could provide ideas for vaccine development.Conclusion:The results indicate that the analysis of human P2X7R protein that is based on bioinformatics method has certain reliability.P2X7R is involved in the development of inflammatory diseases,and the antigenic epitope of B,Th and CTL cells screened out by prediction will provide the treatment scheme for diseases.展开更多
The central solenoid (CS) composed of cable-in-conduit (CIC) type conductor is animportant part of the HT-7U device. The CS coils can be considered from the viewpoint of micro-mechanics as a composite material. And th...The central solenoid (CS) composed of cable-in-conduit (CIC) type conductor is animportant part of the HT-7U device. The CS coils can be considered from the viewpoint of micro-mechanics as a composite material. And then, the residual stiffness is computed according to themicro-damage modeling of continuum damage mechanics. These material properties have beenused as input data for finite element method (FEM) analysis. In this paper the computationalanaysis of the stress and the displacement on the central solenoid are made by the finite elementanalysis system COSMOS/M2.0 under Operating temperature. According to the analytical results,the CS coils are all satisfied with designed safety criteria.展开更多
In this paper, the mechanical strength of the toroidal field (TF) magnets of HT-7U with the electromagnetic force in different magnetic fields is emphatically analyzed by means of finite element method. The model and ...In this paper, the mechanical strength of the toroidal field (TF) magnets of HT-7U with the electromagnetic force in different magnetic fields is emphatically analyzed by means of finite element method. The model and feasible method of computation are put forward. Some important conclusions are made available for reference in the design and construction of TF for HT-7U.展开更多
A perpendicular neutral particle analyzer (NPA) is used on HT-7 tokamak experiment to provide the measurements of neutral particle flux and ion temperature. The measured results were compared with calculated data by ...A perpendicular neutral particle analyzer (NPA) is used on HT-7 tokamak experiment to provide the measurements of neutral particle flux and ion temperature. The measured results were compared with calculated data by Monte-carlo method for ohmic heating. In lower hybrid current drive (LHCD) experiments, the ion heating of LHCD was identified. The chargeexchange neutral particle flux enhanced was observed. The energy spectrum clearly showed a high-energy ions tail. The bulk ion temperature increased by 0.4-0.5 keV after the onset of LHCD. Efficient ion heating of 1 eV. kW-1 was obtained.展开更多
The central solenoid is an important part of the HT-7U device. In this paper， the computational analysis of the stress and the displacement on the pre-load structures of the central solenoid have been made by the fin...The central solenoid is an important part of the HT-7U device. In this paper， the computational analysis of the stress and the displacement on the pre-load structures of the central solenoid have been made by the finite element analysis system COSMOS/M2.0 under room and/or operating temperature. According to the analytical results, the clip aprons and compression plates are all satisfied with safety design criteria.展开更多
基金This work was supported by the National Meg-science Engineering Project of the Chinese Government.
文摘Under the condition of steady state, the pressure drop of coolant is mainly caused by friction along the cable. In the CICC (cable-in-conduit-conductor), helium flow within the conductor consists of two parallel interconnected tubes. The velocity distribution has some differece between the central channel and conductor space. The region of Reynolds number is from 103 to 106. This paper describes the calculation of pressure drop of HT-7U CICC at various mass flows. It is assumed that the coolant flows in two parallel, rough tubes during the calculation.
基金supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions of China PAPD。
文摘Previous research revealed the positive activity of matrix metalloproteinase 7(MMP7) on migration and myelin regeneration of Schwa nn cells(SCs). However, understanding of the molecular changes and biological activities induced by increased amounts of MMP7 in SCs remains limited. To better understand the underlying molecular events, primary SCs were isolated from the sciatic nerve stump of newborn rats and cultured with 10 nM human MMP7 for 24 hours. The results of genetic testing were analyzed at a relatively relaxed threshold value(fold change ≥ 1.5 and P-value < 0.05). Upon MMP7 exposure, 149 genes were found to be upregulated in SCs, whereas 133 genes were downregulated. Gene Ontology analysis suggested that many differentially expressed molecules were related to cellular processes, single-organism processes, and metabolic processes. Kyoto Enrichment of Genes and Genomes pathway analysis further indicated the critical involvement of cell signaling and metabolism in MMP7-induced molecular regulation of SCs. Results of Ingenuity Pathway Analysis(IPA) also revealed that MMP7 regulates biological processes, molecular functions, cellular components, diseases and functions, biosynthesis, material metabolism, cell movement, and axon guidance. The outcomes of further analysis will deepen our comprehension of MMP7-induced biological changes in SCs. This study was approved by the Laboratory Animal Ethics Committee of Nantong University, China(approval No. 20190225-004) on February 27, 2019.
基金supported by the National High Technology Research and Development Program of China(2006AA10Z136)
文摘TSARG7 is a novel member of the acyltransferase family since its sequence possesses the highly conserved phosphate acyltransferase （PlsC） domain existing in all acyltransferase-like proteins. The porcine TSARG7 had been identified by cloning in silico but had not been confirmed experimentally. The full-length mRNA of porcine TSARG7 gene was sequenced and two splice variants were discovered. The full-length cDNA of TSARG7 variant 1 was 2 513 bp and variant 2 was 2 634 bp. The putative porcine TSARG7 proteins, which were located in the cytoplasm, encoded 458 and 456 amino acids, respectively. Real-time PCR analysis showed that TSARG7 gene was expressed in various tissues, but at different levels. The expression levels of this gene were higher in the skeletal muscle, heart, and testis than that in other tissues, suggesting that the TSARG7 gene played a role in procine skeletal muscle, heart, and testis functions.
文摘The HT-7U super-conducting tokamak is a full super-conducting magnetically confined fusion device, It mainly consists of super-conducting toroidal field (TF) coils and super conducting poloidal field (PF) coils. This paper describes the distribution of magnetic field, ripple and electromagnetic loads of TF system, some results are necessary to analyze and calculate the stresses and deformation on TF system by a finite element method. Meanwhile, in this paper, the main scope of the calculation is carried out for the case of constant magnetic field on conductor of the TF coil winding in order to provide electromagnet parameters for the quench analysis of Cable-in-Conduit Conductor (CICC) of TF system in HT-7U.
文摘The vacuum vessel of the HT-7U superconducting Tokamak is designed as an allmetal welded double-wall structure with a number of radial and vertical ports. With characteristicsof ultrahigh vacuum and thin shell, the analysis on stability is very important to the design. Toachieve a successful final design, a threedimension buckling model has been performed using thefinite element program CoSMOS/M2.0. For all the cases having been considered, a 1/16 segmentof the whole toric shell are used to calculate the linear critical buckling load (Pc.,,) under auniform and nonwhform external pressure. As expected, the structure has a good capability ofwithstanding the applied loads.
文摘BACKGROUND The clinical manifestations of trisomy 7 mosaicism are diverse and nonspecific,so prenatal diagnosis is very difficult.CASE SUMMARY Two pregnant women with abnormal prenatal screening results were included.One was a 22-year-old woman(G1P0).At 31st week of gestation,ultrasound revealed that the posterior horn of the left lateral ventricle was 10 mm and the right renal pelvis had a separation of 7 mm.The other pregnant woman was 33 years old(G2P1L1A0),and her fetus was found to have a cardiac malformation at the 24th week of gestation.Copy number variation sequencing,whole-exome sequencing and karyotype analysis were carried out after amniocentesis,and both fetuses were diagnosed with trisomy 7 mosaicism.After parental counseling,one woman continued the pregnancy,and the other woman terminated the pregnancy.CONCLUSION In trisomy 7 mosaicism,the low proportion of trisomy does not lead to abortion,but can result in abnormal fetal development,which can be detected via ultrasound.Therefore,clinicians need to pay more attention to various aspects of fetal growth and development,combining with imaging,cellular,molecular genetics and other methods to perform comprehensive evaluations of fetuses to provide more reliable genetic counseling for pregnant women.
基金Supported by Special Fund for Agro-scientific Research in the Public Interest from the Ministry of Agriculture(201003061)Key Project of Livestock and Poultry Breeding of Sichuan Province(01NG029-18)
文摘In this study, full-length CDS sequence of IGFBP-7 gene was cloned from Liangshan semi-fine wool sheep with RT-PCR method and analyzed with bioinformatics methods. The results showed that the full-length CDS sequence of IGFBP-7 gene in Liangshan semi-fine wool sheep was 846 bp in length, encoding 282 amino acids. The CDS sequence shared 99%, 95% and 90% homology with bovine, human and rat, respectively; the amino acid sequence shared 98%, 93% and 89%, respectively. The GenBank accession number was FJ589640.1. The amino acid molecular weight of IGFBP-7 was 29.0 kD, and the theoretical isoelec- tric point （pl） was 8.25. The result of phylogenetic analysis showed that IGFBP-7 gone in Liangshan semi-fine wool sheep exhibited close phylogenetic relationships with bovine, goat and other mammals, and distant phylogenetic relationships with Danio rerio and Haliotis diversicolor. IGFBP-7 gene had uniformly distributed hy- drophobic and hydrophilic regions, harboring one signal peptide, two transmembrane regions, 16 phosphorylation sites, four N-glycosylation sites and one O-glyco- sylation site. The result of secondary structure analysis showed that the random coil, or-helix and β-sheet regions accounted for 64.89%, 19.86% and 15.25%, respectively. The result of tertiary structure analysis showed that IGFBP-7 harbors an IGFBP_N domain and an Ig-like domain. This study provided scientific basis for further investigating the function of IGFBP-7 gene in sheep.
文摘The displacement, velocity and acceleration analysis of the general spatial 7R mechanism is discussed in this paper, fused on the method proposed in Ref. [2], an input-output algebra equation of the 16th degree in the tan-half-angle of the output angular displacement is derived. The derivation process and computation are considerably simple. A program written in Allanguage is used to derive the coefficients of displacement equations: therefore the amount of manual work is greatly decreased. The results are verified by a numerical example. The researches of this paper and Ref. [5]found a base for establishing an expert system of spatial mechanism analysis in the future.
文摘Human papillomavirus 16 (HPV-16) is a major high-risk type causing cervical cancer. The E6 and E7 genes in HPV-16 are the major virulent genes in HPV, and we wanted to investigate the polymorphism of E6 and E7 genes of HPV-16 originated from Jingjiang, Jiangsu province. In research, HPV-16 sample was collected, and the E6 and E7 genes fragments were amplified by PCR assay. The sequences of E6 and E7 genes were used for phylogenetic analysis by Mega 5.0 software. By comparison, the major mutations of E6 gene were T178G (41.67%) and G658A (17%), as well as C58G, T61A and G188C (14%), T61C and C656A (11%). The mutation of E7 gene was mainly C491A and T935A (23%);G514C, G937C and G519C (11%). The 68 nucleotide site deficiency (69.4%) of E6 and 535 nucleotide site deficiency (23%) of E7 were dominant. In our study, we did not find the relevance between the E6 and E7 genes mutations and pathologic severity. But we think the E6 and E7 genes mutation of HPV-16 might affect vaccine prevention and treatment effect.
基金National Natural Science Foundation of China(No.81770915,81301737)。
文摘Objective:To analyze the structural features of human P2X7R protein,meanwhile homology,protein-protein interaction,and cell epitope were predicted to provide theoretical basis for the diagnosis and treatment of related diseases.Methods:Human P2X7R protein was analyzed and predicted by ProtParam、TMHMM、ProtScale and SignalP 5.0 Server et al.Results:Human P2X7R protein is composed of 595 amino acids,the molecular formula is C 3077 H 4749 N 835 O 871 S 40,with the theoretical isoelectric point PI of 8.62,the instability coefficient is 46.07,the total average hydrophilicity is-0.317,and the protein is an hydrophilic protein instead of secreted protein,no any signal peptide,but transmembrane region is contained,which belong to transmembrane protein.There are 157αhelices and 288 random coils in the secondary structure of human P2X7R protein,accounting for 26.39%and 48.40%of all amino acids,The coverage rate of the three-level structure prediction results is 100%,and the sequence consistency is 80.34%,and the ramachandran plot show that the predicted structure is relatively stability.The interaction of proteins show that there are a variety of proteins interacting with human P2X7R,and P2X7R was closely related to inflammation;this protein had many B and T cell epitopes,which could provide ideas for vaccine development.Conclusion:The results indicate that the analysis of human P2X7R protein that is based on bioinformatics method has certain reliability.P2X7R is involved in the development of inflammatory diseases,and the antigenic epitope of B,Th and CTL cells screened out by prediction will provide the treatment scheme for diseases.
基金National Meg-Science Engineering Project of the Chinese Government.
文摘The central solenoid (CS) composed of cable-in-conduit (CIC) type conductor is animportant part of the HT-7U device. The CS coils can be considered from the viewpoint of micro-mechanics as a composite material. And then, the residual stiffness is computed according to themicro-damage modeling of continuum damage mechanics. These material properties have beenused as input data for finite element method (FEM) analysis. In this paper the computationalanaysis of the stress and the displacement on the central solenoid are made by the finite elementanalysis system COSMOS/M2.0 under Operating temperature. According to the analytical results,the CS coils are all satisfied with designed safety criteria.
文摘In this paper, the mechanical strength of the toroidal field (TF) magnets of HT-7U with the electromagnetic force in different magnetic fields is emphatically analyzed by means of finite element method. The model and feasible method of computation are put forward. Some important conclusions are made available for reference in the design and construction of TF for HT-7U.
文摘A perpendicular neutral particle analyzer (NPA) is used on HT-7 tokamak experiment to provide the measurements of neutral particle flux and ion temperature. The measured results were compared with calculated data by Monte-carlo method for ohmic heating. In lower hybrid current drive (LHCD) experiments, the ion heating of LHCD was identified. The chargeexchange neutral particle flux enhanced was observed. The energy spectrum clearly showed a high-energy ions tail. The bulk ion temperature increased by 0.4-0.5 keV after the onset of LHCD. Efficient ion heating of 1 eV. kW-1 was obtained.
文摘The central solenoid is an important part of the HT-7U device. In this paper， the computational analysis of the stress and the displacement on the pre-load structures of the central solenoid have been made by the finite element analysis system COSMOS/M2.0 under room and/or operating temperature. According to the analytical results, the clip aprons and compression plates are all satisfied with safety design criteria.
