This article is devoted to characterizing the boundedness and compactness of multiplication operators from Hardy spaces to weighted Bergman spaces in the unit ball of ■.
Hemorrhage is the leading cause of combat deaths,which is a primary lesson learned from modern warfare.[1]If temporary hemostasis is not available,the mortality of non-compressible torso hemorrhage(NCTH),a potentially...Hemorrhage is the leading cause of combat deaths,which is a primary lesson learned from modern warfare.[1]If temporary hemostasis is not available,the mortality of non-compressible torso hemorrhage(NCTH),a potentially preventable death(PPD),is as high as 85.5%.[2]展开更多
In this article, the authors consider the weighted bounds for the singular integral operator defined by ■where ? is homogeneous of degree zero and has vanishing moment of order one, and A is a function on Rnsuch that...In this article, the authors consider the weighted bounds for the singular integral operator defined by ■where ? is homogeneous of degree zero and has vanishing moment of order one, and A is a function on Rnsuch that ?A ∈ BMO(R^n). By sparse domination, the authors obtain some quantitative weighted bounds for TAwhen ? satisfies regularity condition of Lr-Dini type for some r ∈(1, ∞).展开更多
Background:Cancer poses a significant global challenge,and with the pro-jected rise in cancer incidence,there is an urgent need to discover new targets and treatments to improve patient outcomes.Recent advancements in...Background:Cancer poses a significant global challenge,and with the pro-jected rise in cancer incidence,there is an urgent need to discover new targets and treatments to improve patient outcomes.Recent advancements in geno-mics technologies have enhanced our understanding of cancer's complexities and led to the emergence of pan‐cancer analysis as a valuable approach for identifying tumor targets.Torsin‐1A‐interacting protein 1(TOR1AIP1)is a membrane protein involved in various cellular processes.Emerging evidence suggests its potential involvement in cancer.Methods:In this study,we conducted a comprehensive analysis of multiple databases to explore TOR1AIP1 expression across different cancer types and stages.We also investigated its correlation with clinical outcomes,such as survival rates and drug sensitivity.Results:The results of our analysis showed significant deregulation of TOR1AIP1 expression in multiple cancer types and its association with clinical outcomes,with a particular emphasis on kidney renal clear cell carcinoma.The results of our study highlight the potential predictive value of TOR1AIP1 in cancer prognosis and therapy.Conclusions:This study establishes a solid foundation and rationale for future experimental investigations,which will contribute to a deeper under-standing of the significance of TOR1AIP1 in different cancer types,specifically in kidney renal clear cell carcinoma.展开更多
For 1≤p<∞we introduce a notion of"p-mean oscillation"on C^(n)in terms of the q metric induced by reproducing kernel of F_(ψ)^(2).It is shown that the densely-defined Hankel operators Hf,Hf:F_(ψ)^(p)→...For 1≤p<∞we introduce a notion of"p-mean oscillation"on C^(n)in terms of the q metric induced by reproducing kernel of F_(ψ)^(2).It is shown that the densely-defined Hankel operators Hf,Hf:F_(ψ)^(p)→F_(ψ)^(p),are simultaneously bounded if and only if f is of bounded“p-mean oscillation”.Furthermore,it is also shown that the densely-defined Hankel operators Hf、Hf:F_(ψ)^(p)→F_(ψ)^(p),are simultaneously compact if and only if f is of vanishing“p-mean oscillation”.Here the weightψis a positive function of logarithmic grow th sat isfying certain suitable conditions.展开更多
The purpose of the present paper is to deliberate *-conformal Yamabe soliton,whose potential vector field is torse-forming on Kenmotsu manifold.Here,we have shown the nature of the soliton and find the scalar curvatur...The purpose of the present paper is to deliberate *-conformal Yamabe soliton,whose potential vector field is torse-forming on Kenmotsu manifold.Here,we have shown the nature of the soliton and find the scalar curvature when the manifold admitting *-conformal Yamabe soliton on Kenmotsu manifold.Next,we have evolved the characterization of the vector field when the manifold satisfies *-conformal Yamabe soliton.Also we have embellished some applications of vector field as torse-forming in terms of *-conformal Yamabe soliton on Kenmotsu manifold.We have developed an example of *-conformal Yamabe soliton on 3-dimensional Kenmotsu manifold to prove our findings.展开更多
Website fingerprinting,also known asWF,is a traffic analysis attack that enables local eavesdroppers to infer a user’s browsing destination,even when using the Tor anonymity network.While advanced attacks based on de...Website fingerprinting,also known asWF,is a traffic analysis attack that enables local eavesdroppers to infer a user’s browsing destination,even when using the Tor anonymity network.While advanced attacks based on deep neural network(DNN)can performfeature engineering and attain accuracy rates of over 98%,research has demonstrated thatDNNis vulnerable to adversarial samples.As a result,many researchers have explored using adversarial samples as a defense mechanism against DNN-based WF attacks and have achieved considerable success.However,these methods suffer from high bandwidth overhead or require access to the target model,which is unrealistic.This paper proposes CMAES-WFD,a black-box WF defense based on adversarial samples.The process of generating adversarial examples is transformed into a constrained optimization problem solved by utilizing the Covariance Matrix Adaptation Evolution Strategy(CMAES)optimization algorithm.Perturbations are injected into the local parts of the original traffic to control bandwidth overhead.According to the experiment results,CMAES-WFD was able to significantly decrease the accuracy of Deep Fingerprinting(DF)and VarCnn to below 8.3%and the bandwidth overhead to a maximum of only 14.6%and 20.5%,respectively.Specially,for Automated Website Fingerprinting(AWF)with simple structure,CMAES-WFD reduced the classification accuracy to only 6.7%and the bandwidth overhead to less than 7.4%.Moreover,it was demonstrated that CMAES-WFD was robust against adversarial training to a certain extent.展开更多
The phosphatidylinositol 3-kinase(PI3K) pathway is frequently activated in human cancers.Class I PI3 Ks are lipid kinases that phosphorylate phosphatidylinositol 4,5-bisphosphate(PIP2) at the 3-OH of the inositol ring...The phosphatidylinositol 3-kinase(PI3K) pathway is frequently activated in human cancers.Class I PI3 Ks are lipid kinases that phosphorylate phosphatidylinositol 4,5-bisphosphate(PIP2) at the 3-OH of the inositol ring to generate phosphatidylinositol 3,4,5-trisphosphate(PIP3), which in turn activates Akt and the downstream effectors like mammalian target of rapamycin(m TOR) to play key roles in carcinogenesis. Therefore, PI3 K has become an important anticancer drug target, and currently there is very high interest in the pharmaceutical development of PI3 K inhibitors. Idelalisib has been approved in USA and Europe as the first-in-class PI3 K inhibitor for cancer therapy. Dozens of other PI3 K inhibitors including BKM120 and ZSTK474 are being evaluated in clinical trials. Multifaceted studies on these PI3 K inhibitors are being performed, such as single and combinational efficacy, resistance, biomarkers,etc. This review provides an introduction to PI3 K and summarizes key advances in the development of PI3 K inhibitors.展开更多
基金Supported by the National Natural Science Foundation of China(11601400 and 11771441)the Fundamental Research Funds for the Central Universities(2017IB012 and 2017IVB064)
文摘This article is devoted to characterizing the boundedness and compactness of multiplication operators from Hardy spaces to weighted Bergman spaces in the unit ball of ■.
基金This study was supported by the Clinical Technology Innovation and Cultivation Project of Army Medical University(CX2019JS109)the Innovative Project of Daping Hospital for Clinical Medicine(2019CXLCA002).
文摘Hemorrhage is the leading cause of combat deaths,which is a primary lesson learned from modern warfare.[1]If temporary hemostasis is not available,the mortality of non-compressible torso hemorrhage(NCTH),a potentially preventable death(PPD),is as high as 85.5%.[2]
基金supported by Teacher Research Capacity Promotion Program of Beijing Normal University ZhuhaiNNSF of China under Grant#11461065supported by the NNSF of China under grant#11871108
文摘In this article, the authors consider the weighted bounds for the singular integral operator defined by ■where ? is homogeneous of degree zero and has vanishing moment of order one, and A is a function on Rnsuch that ?A ∈ BMO(R^n). By sparse domination, the authors obtain some quantitative weighted bounds for TAwhen ? satisfies regularity condition of Lr-Dini type for some r ∈(1, ∞).
文摘Background:Cancer poses a significant global challenge,and with the pro-jected rise in cancer incidence,there is an urgent need to discover new targets and treatments to improve patient outcomes.Recent advancements in geno-mics technologies have enhanced our understanding of cancer's complexities and led to the emergence of pan‐cancer analysis as a valuable approach for identifying tumor targets.Torsin‐1A‐interacting protein 1(TOR1AIP1)is a membrane protein involved in various cellular processes.Emerging evidence suggests its potential involvement in cancer.Methods:In this study,we conducted a comprehensive analysis of multiple databases to explore TOR1AIP1 expression across different cancer types and stages.We also investigated its correlation with clinical outcomes,such as survival rates and drug sensitivity.Results:The results of our analysis showed significant deregulation of TOR1AIP1 expression in multiple cancer types and its association with clinical outcomes,with a particular emphasis on kidney renal clear cell carcinoma.The results of our study highlight the potential predictive value of TOR1AIP1 in cancer prognosis and therapy.Conclusions:This study establishes a solid foundation and rationale for future experimental investigations,which will contribute to a deeper under-standing of the significance of TOR1AIP1 in different cancer types,specifically in kidney renal clear cell carcinoma.
文摘For 1≤p<∞we introduce a notion of"p-mean oscillation"on C^(n)in terms of the q metric induced by reproducing kernel of F_(ψ)^(2).It is shown that the densely-defined Hankel operators Hf,Hf:F_(ψ)^(p)→F_(ψ)^(p),are simultaneously bounded if and only if f is of bounded“p-mean oscillation”.Furthermore,it is also shown that the densely-defined Hankel operators Hf、Hf:F_(ψ)^(p)→F_(ψ)^(p),are simultaneously compact if and only if f is of vanishing“p-mean oscillation”.Here the weightψis a positive function of logarithmic grow th sat isfying certain suitable conditions.
基金Supported by Swami Vivekananda Merit Cum Means ScholarshipGovernment of West Bengal,India。
文摘The purpose of the present paper is to deliberate *-conformal Yamabe soliton,whose potential vector field is torse-forming on Kenmotsu manifold.Here,we have shown the nature of the soliton and find the scalar curvature when the manifold admitting *-conformal Yamabe soliton on Kenmotsu manifold.Next,we have evolved the characterization of the vector field when the manifold satisfies *-conformal Yamabe soliton.Also we have embellished some applications of vector field as torse-forming in terms of *-conformal Yamabe soliton on Kenmotsu manifold.We have developed an example of *-conformal Yamabe soliton on 3-dimensional Kenmotsu manifold to prove our findings.
基金the Key JCJQ Program of China:2020-JCJQ-ZD-021-00 and 2020-JCJQ-ZD-024-12.
文摘Website fingerprinting,also known asWF,is a traffic analysis attack that enables local eavesdroppers to infer a user’s browsing destination,even when using the Tor anonymity network.While advanced attacks based on deep neural network(DNN)can performfeature engineering and attain accuracy rates of over 98%,research has demonstrated thatDNNis vulnerable to adversarial samples.As a result,many researchers have explored using adversarial samples as a defense mechanism against DNN-based WF attacks and have achieved considerable success.However,these methods suffer from high bandwidth overhead or require access to the target model,which is unrealistic.This paper proposes CMAES-WFD,a black-box WF defense based on adversarial samples.The process of generating adversarial examples is transformed into a constrained optimization problem solved by utilizing the Covariance Matrix Adaptation Evolution Strategy(CMAES)optimization algorithm.Perturbations are injected into the local parts of the original traffic to control bandwidth overhead.According to the experiment results,CMAES-WFD was able to significantly decrease the accuracy of Deep Fingerprinting(DF)and VarCnn to below 8.3%and the bandwidth overhead to a maximum of only 14.6%and 20.5%,respectively.Specially,for Automated Website Fingerprinting(AWF)with simple structure,CMAES-WFD reduced the classification accuracy to only 6.7%and the bandwidth overhead to less than 7.4%.Moreover,it was demonstrated that CMAES-WFD was robust against adversarial training to a certain extent.
文摘The phosphatidylinositol 3-kinase(PI3K) pathway is frequently activated in human cancers.Class I PI3 Ks are lipid kinases that phosphorylate phosphatidylinositol 4,5-bisphosphate(PIP2) at the 3-OH of the inositol ring to generate phosphatidylinositol 3,4,5-trisphosphate(PIP3), which in turn activates Akt and the downstream effectors like mammalian target of rapamycin(m TOR) to play key roles in carcinogenesis. Therefore, PI3 K has become an important anticancer drug target, and currently there is very high interest in the pharmaceutical development of PI3 K inhibitors. Idelalisib has been approved in USA and Europe as the first-in-class PI3 K inhibitor for cancer therapy. Dozens of other PI3 K inhibitors including BKM120 and ZSTK474 are being evaluated in clinical trials. Multifaceted studies on these PI3 K inhibitors are being performed, such as single and combinational efficacy, resistance, biomarkers,etc. This review provides an introduction to PI3 K and summarizes key advances in the development of PI3 K inhibitors.
