Background: Since we are very successful in the operation of hallux valgus using a transverse sub-capital osteotomy fixated with an intramedullary angle-stable locking plate, and a tailors bunion is understood as a re...Background: Since we are very successful in the operation of hallux valgus using a transverse sub-capital osteotomy fixated with an intramedullary angle-stable locking plate, and a tailors bunion is understood as a reversed hallux valgus, we have applied the operation also for such indication. Method: The osteotomy was carried out at a straight V. metatarsal subcapitally, and in case of an outwardly curved V. metatarsal at the bending location. The intramedullary plates are available in different designs and the plate and screws disappear completely in the bone, so the soft tissues are not disturbed. The head of the plate is either straight or curved in order to shift the distal fragment sufficiently. Results: 26 patients were operated within a period of 5 years (2008-2012). 21 patients were followed up after an average of 34.4 months. The IM angle IV/V could be improved by an average of 11.76 to an average of 4.10. This is a highliy significant pre- to postoperative difference of 7.66 (t = 15.07, p < 0.001). The AOFAS score was improved by an average of 42.24 points from 55.76 points preoperatively to 98.00 points postoperative. There was no pseudo-arthrosis and no wound healing impairment. All patients were either satisfied or very satisfied with the surgery. Conclusion: This method does not have the disadvantages of the other common operations of the Tailors bunion and is applied now as a standard method in this deformity.展开更多
Sleeve pattern design of men’ s tailored - suit is one of the most difficult problems of clothing pattern design. Based on the experimental studies of armhole girth, the difference of armhole width and crown height, ...Sleeve pattern design of men’ s tailored - suit is one of the most difficult problems of clothing pattern design. Based on the experimental studies of armhole girth, the difference of armhole width and crown height, crown angle, under sleeve curve’s diagonal line length, crown ease and its distribution rule, this paper mainly deals with the sleeve pattern design of tailored - suit for Chinese men. The influences of these factors are discussed and furthermore, some qualitative, quantifiable conclusions are drawn to design perfect pattern of men’ s tailored - suit sleeve.展开更多
BACKGROUND Hallux valgus(HV)is a common foot deformity that manifests with increasing age,especially in women.The associated foot pain causes impaired gait and decreases quality of life.Moderate and severe HV is a def...BACKGROUND Hallux valgus(HV)is a common foot deformity that manifests with increasing age,especially in women.The associated foot pain causes impaired gait and decreases quality of life.Moderate and severe HV is a deformity that is charac-terized by the involvement of lesser rays and requires complex surgical treatment.In this study,we attempted to develop a procedure for this condition.AIM To analyse the treatment results of patients who underwent simultaneous surgical correction of all parts of a static forefoot deformity.METHODS We conducted a prospective clinical trial between 2016 and 2021 in which 30 feet with moderate or severe HV associated with Tailor’s bunion and metatarsalgia were surgically treated via a new method involving surgical correction of all associated problems.This method included a modified Lapidus procedure,M2M3 tarsometatarsal arthrodesis,intermetatarsal fusion of the M4 and M5 bases,and the use of an original external fixation apparatus to enhance correction power.Preoperative,postoperative,and final follow-up radiographic data and American Orthopaedic Foot and Ankle Society(AOFAS)scores were compared,and P values<0.05 were considered to indicate statistical significance.RESULTS The study included 28 females(93.3%)and 2 males feet(6.7%),20(66.7%)of whom had a moderate degree of HV and 10(33.3%)of whom had severe deformity.M2 and M3 metatarsalgia was observed in 21 feet,and 9 feet experienced pain only at M2.The mean follow-up duration was 11 months.All patients had good correction of the HV angle[preoperative median,36.5 degrees,interquartile range(IQR):30-45;postoperative median,10 degrees,IQR:8.8-10;follow-up median,11.5 degrees,IQR:10-14;P<0.01].At follow-up,metatarsalgia was resolved in most patients(30 vs 5).There was a clinically negligible decrease in the corrected angles at the final follow-up,and the overall AOFAS score was significantly better(median,65 points,IQR:53.8-70;vs 80 points,IQR:75-85;P<0.01).CONCLUSION The developed method showed good sustainability of correction power in a small sample of patients at the one-year follow-up.Randomized clinical trials with larger samples,as well as long-term outcome assessments,are needed in the future.展开更多
In a long-term follow-up study (average, 6.5 years) of 112 feet (90 pa-tients) subjected to Keller’s operation for hallux valgus deformity, the author observed arelationship between Keller’s operation and the metata...In a long-term follow-up study (average, 6.5 years) of 112 feet (90 pa-tients) subjected to Keller’s operation for hallux valgus deformity, the author observed arelationship between Keller’s operation and the metatarsalgia which was located beneaththe central metatarsal heads. The data showed that the metatarsalgia developed or was ag-gravated in 26 feet (23%), and was eliminated or alleviated in 23 feet (21%) afterKeller’s operation. When more than one-third of the proximal phalanx of the big toe wasresected, the incidence of the metatarsalgia obviously increased following surgery. Theautho rpreferred a "Z" lengthening of the extensor hallucis longus tendon instead ofresecting excessive proximal phalanx. The total incidence of the metatarsalgia was 36%(40 feet) preoperatively and 38% (43 feet) postoperatively. This result indicated thatthere was no obvious difference in the incidence of the preoperative and postoperativemetatarsalgia. No more than one-third of the proximal phalanx of the big toe should beremoved. This seems to reduce the incidence of the metatarsalgia after Keller’s operation.After operation, the three princepal symptoms of hallux valgus deformity, painful bunionand difficulty in shoe-wearing were improved for more than 95% in the 112 feet.Eighty one% of the patients were satisfied with the result of the operation. We considerthat this method is one of the effective operation for correcting the hallux valgusdeformity and it is also important to select suitable patients.展开更多
背景：对于扇形足的有效治疗方法目前仍存在争议，常用的截骨手术损伤大、并发症多、疗效不确定。目的：尝试采用双Endobutton带袢接骨板结合软组织手术纠正扇形足，并评价其初期治疗效果。方法：2012年1月至2012年6月，对6例（8足）扇...背景：对于扇形足的有效治疗方法目前仍存在争议，常用的截骨手术损伤大、并发症多、疗效不确定。目的：尝试采用双Endobutton带袢接骨板结合软组织手术纠正扇形足，并评价其初期治疗效果。方法：2012年1月至2012年6月，对6例（8足）扇形足患者采用第1、2跖骨间双Endobutton带袢接骨板结合软组织手术，即第1、2跖骨头双Endobutton带袢接骨板固定、囊与趾囊切除、增生骨赘切除和第1、5跖趾关节囊紧缩联合应用于纠正扇形足畸形，评价患足手术前后影像学改变及美国足踝外科协会（American Orthopedic Foot and Ankle Society， AOFAS）评分差异。结果：所有患者均获随访。随访时间12~20个月，平均（17.7±4.8）个月。手术前后外翻角（27.0°±5.1° vs 15.9°±4.2°， P＜0.05）、第1、2跖骨间角（16.3°±3.2° vs 8.3°±1.9°，P＜0.05）和第1、5跖骨头间距[（9.0±1.0）cm vs（8.0±1.0）cm，P＜0.05]改善明显，术后AOFAS评分较术前提高了55.5%[（50.1±8.7）分vs（77.9±7.3）分，P＜0.05]。结论：第1、2跖骨间双Endobutton带袢接骨板结合（趾）囊炎切除手术可以有效纠正扇形足畸形，手术创伤小、术后可早期负重、患足疼痛改善明显、功能提高显著，但远期疗效仍需进一步观察。展开更多
The pathological origin of Alzheimer’s disease(AD)is still shrouded in mystery,despite intensive worldwide research efforts.The selective visualization ofβ-amyloid(Aβ),the most abundant proteinaceous deposit in AD,...The pathological origin of Alzheimer’s disease(AD)is still shrouded in mystery,despite intensive worldwide research efforts.The selective visualization ofβ-amyloid(Aβ),the most abundant proteinaceous deposit in AD,is pivotal to reveal AD pathology.To date,several small-molecule fluorophores for Aβspecies have been developed,with increasing binding affinities.In the current work,two organic small-molecule dioxaborine-derived fluorophores were rationally designed through tailoring the hydrophobicity with the aim to enhance the binding affinity for Aβ_(1-42) fibrils-while concurrently preventing poor aqueous solubility-via biannulate donor motifs in D-π-A dyes.An unprecedented sub-nanomolar affinity was found(K_(d)=0.62±0.33 nM)and applied to super-sensitive and red-emissive fluorescent staining of amyloid plaques in cortical brain tissue ex vivo.These fluorophores expand the dioxaborine-curcumin-based family of Aβ-sensitive fluorophores with a promising new imaging agent.展开更多
文摘Background: Since we are very successful in the operation of hallux valgus using a transverse sub-capital osteotomy fixated with an intramedullary angle-stable locking plate, and a tailors bunion is understood as a reversed hallux valgus, we have applied the operation also for such indication. Method: The osteotomy was carried out at a straight V. metatarsal subcapitally, and in case of an outwardly curved V. metatarsal at the bending location. The intramedullary plates are available in different designs and the plate and screws disappear completely in the bone, so the soft tissues are not disturbed. The head of the plate is either straight or curved in order to shift the distal fragment sufficiently. Results: 26 patients were operated within a period of 5 years (2008-2012). 21 patients were followed up after an average of 34.4 months. The IM angle IV/V could be improved by an average of 11.76 to an average of 4.10. This is a highliy significant pre- to postoperative difference of 7.66 (t = 15.07, p < 0.001). The AOFAS score was improved by an average of 42.24 points from 55.76 points preoperatively to 98.00 points postoperative. There was no pseudo-arthrosis and no wound healing impairment. All patients were either satisfied or very satisfied with the surgery. Conclusion: This method does not have the disadvantages of the other common operations of the Tailors bunion and is applied now as a standard method in this deformity.
基金This work wus supported hy China Textile Universily and the corporatoin foundation
文摘Sleeve pattern design of men’ s tailored - suit is one of the most difficult problems of clothing pattern design. Based on the experimental studies of armhole girth, the difference of armhole width and crown height, crown angle, under sleeve curve’s diagonal line length, crown ease and its distribution rule, this paper mainly deals with the sleeve pattern design of tailored - suit for Chinese men. The influences of these factors are discussed and furthermore, some qualitative, quantifiable conclusions are drawn to design perfect pattern of men’ s tailored - suit sleeve.
文摘BACKGROUND Hallux valgus(HV)is a common foot deformity that manifests with increasing age,especially in women.The associated foot pain causes impaired gait and decreases quality of life.Moderate and severe HV is a deformity that is charac-terized by the involvement of lesser rays and requires complex surgical treatment.In this study,we attempted to develop a procedure for this condition.AIM To analyse the treatment results of patients who underwent simultaneous surgical correction of all parts of a static forefoot deformity.METHODS We conducted a prospective clinical trial between 2016 and 2021 in which 30 feet with moderate or severe HV associated with Tailor’s bunion and metatarsalgia were surgically treated via a new method involving surgical correction of all associated problems.This method included a modified Lapidus procedure,M2M3 tarsometatarsal arthrodesis,intermetatarsal fusion of the M4 and M5 bases,and the use of an original external fixation apparatus to enhance correction power.Preoperative,postoperative,and final follow-up radiographic data and American Orthopaedic Foot and Ankle Society(AOFAS)scores were compared,and P values<0.05 were considered to indicate statistical significance.RESULTS The study included 28 females(93.3%)and 2 males feet(6.7%),20(66.7%)of whom had a moderate degree of HV and 10(33.3%)of whom had severe deformity.M2 and M3 metatarsalgia was observed in 21 feet,and 9 feet experienced pain only at M2.The mean follow-up duration was 11 months.All patients had good correction of the HV angle[preoperative median,36.5 degrees,interquartile range(IQR):30-45;postoperative median,10 degrees,IQR:8.8-10;follow-up median,11.5 degrees,IQR:10-14;P<0.01].At follow-up,metatarsalgia was resolved in most patients(30 vs 5).There was a clinically negligible decrease in the corrected angles at the final follow-up,and the overall AOFAS score was significantly better(median,65 points,IQR:53.8-70;vs 80 points,IQR:75-85;P<0.01).CONCLUSION The developed method showed good sustainability of correction power in a small sample of patients at the one-year follow-up.Randomized clinical trials with larger samples,as well as long-term outcome assessments,are needed in the future.
文摘In a long-term follow-up study (average, 6.5 years) of 112 feet (90 pa-tients) subjected to Keller’s operation for hallux valgus deformity, the author observed arelationship between Keller’s operation and the metatarsalgia which was located beneaththe central metatarsal heads. The data showed that the metatarsalgia developed or was ag-gravated in 26 feet (23%), and was eliminated or alleviated in 23 feet (21%) afterKeller’s operation. When more than one-third of the proximal phalanx of the big toe wasresected, the incidence of the metatarsalgia obviously increased following surgery. Theautho rpreferred a "Z" lengthening of the extensor hallucis longus tendon instead ofresecting excessive proximal phalanx. The total incidence of the metatarsalgia was 36%(40 feet) preoperatively and 38% (43 feet) postoperatively. This result indicated thatthere was no obvious difference in the incidence of the preoperative and postoperativemetatarsalgia. No more than one-third of the proximal phalanx of the big toe should beremoved. This seems to reduce the incidence of the metatarsalgia after Keller’s operation.After operation, the three princepal symptoms of hallux valgus deformity, painful bunionand difficulty in shoe-wearing were improved for more than 95% in the 112 feet.Eighty one% of the patients were satisfied with the result of the operation. We considerthat this method is one of the effective operation for correcting the hallux valgusdeformity and it is also important to select suitable patients.
文摘背景：对于扇形足的有效治疗方法目前仍存在争议，常用的截骨手术损伤大、并发症多、疗效不确定。目的：尝试采用双Endobutton带袢接骨板结合软组织手术纠正扇形足，并评价其初期治疗效果。方法：2012年1月至2012年6月，对6例（8足）扇形足患者采用第1、2跖骨间双Endobutton带袢接骨板结合软组织手术，即第1、2跖骨头双Endobutton带袢接骨板固定、囊与趾囊切除、增生骨赘切除和第1、5跖趾关节囊紧缩联合应用于纠正扇形足畸形，评价患足手术前后影像学改变及美国足踝外科协会（American Orthopedic Foot and Ankle Society， AOFAS）评分差异。结果：所有患者均获随访。随访时间12~20个月，平均（17.7±4.8）个月。手术前后外翻角（27.0°±5.1° vs 15.9°±4.2°， P＜0.05）、第1、2跖骨间角（16.3°±3.2° vs 8.3°±1.9°，P＜0.05）和第1、5跖骨头间距[（9.0±1.0）cm vs（8.0±1.0）cm，P＜0.05]改善明显，术后AOFAS评分较术前提高了55.5%[（50.1±8.7）分vs（77.9±7.3）分，P＜0.05]。结论：第1、2跖骨间双Endobutton带袢接骨板结合（趾）囊炎切除手术可以有效纠正扇形足畸形，手术创伤小、术后可早期负重、患足疼痛改善明显、功能提高显著，但远期疗效仍需进一步观察。
基金This research was supported by the National Research Foundation of Korea(CRI project no.2018R1A3B1052702,NRF-2019M3E5D1A01068998,J.S.Kim)the Korea University Graduate School Junior Fellow Research Grant(J.An)+3 种基金the National Research Council of Science&Technology(NST)granted by the Ministry of Science,ICT&Future Planning(MSIP)(No.CRC-15-04-KIST)the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI)and Korea Dementia Research Center(KDRC)the Ministry of Health&Welfare and Ministry of Science and ICT,Republic of Korea(No.HI20C1234)P.V.acknowledges support from Interne Fondsen KU Leuven/Internal Funds KU Leuven(STG/19/029).
文摘The pathological origin of Alzheimer’s disease(AD)is still shrouded in mystery,despite intensive worldwide research efforts.The selective visualization ofβ-amyloid(Aβ),the most abundant proteinaceous deposit in AD,is pivotal to reveal AD pathology.To date,several small-molecule fluorophores for Aβspecies have been developed,with increasing binding affinities.In the current work,two organic small-molecule dioxaborine-derived fluorophores were rationally designed through tailoring the hydrophobicity with the aim to enhance the binding affinity for Aβ_(1-42) fibrils-while concurrently preventing poor aqueous solubility-via biannulate donor motifs in D-π-A dyes.An unprecedented sub-nanomolar affinity was found(K_(d)=0.62±0.33 nM)and applied to super-sensitive and red-emissive fluorescent staining of amyloid plaques in cortical brain tissue ex vivo.These fluorophores expand the dioxaborine-curcumin-based family of Aβ-sensitive fluorophores with a promising new imaging agent.
