目的:探讨Tei指数对于法洛氏四联症(tetralogy of Fallot,TOF)患儿术后的临床价值。方法:自2008年10月至2012年6月间来我院就诊的TOF患儿45例,术后先行超声Tei检测,根据结果分为3组,A组:Tei指数<0.5,B组:0.5≤Tei指数<0.7,C组:Te...目的:探讨Tei指数对于法洛氏四联症(tetralogy of Fallot,TOF)患儿术后的临床价值。方法:自2008年10月至2012年6月间来我院就诊的TOF患儿45例,术后先行超声Tei检测,根据结果分为3组,A组:Tei指数<0.5,B组:0.5≤Tei指数<0.7,C组:Tei指数≥0.7。行超声心动图检查测量左室射血分数(ejection fraction,EF)、计算右心Tei指数、记录呼吸机辅助时间、重症监护室监护时间、正性药物辅助时间、引流量。结果:A组与B组、C组患儿在呼吸机辅助时间、重症监护室监护时间、正性药物辅助时间、引流量等方面差异具有统计学意义。Tei指数与之具有负相关关系,EF在3组中差异无统计学意义。结论:Tei指数可以较敏感准确地反映TOF患儿右室功能的变化,是一个简单且有价值的临床指标。展开更多
Objective To evaluate the fetal cardiac function in gestational diabetes mellitus （GDM） pregnancies under different maternal glycemic controls. Methods Forty four GDM mothers received 78 fetal echocardiographic eval...Objective To evaluate the fetal cardiac function in gestational diabetes mellitus （GDM） pregnancies under different maternal glycemic controls. Methods Forty four GDM mothers received 78 fetal echocardiographic evaluations at three gestational periods （〈28, 28-34 and ≥34 weeks） and were divided into poorly-（DM1） and well-（DM2） controlled groups according to their glycemic control at examination. Seventy uncomplicated mothers were selected as controls. Parameters of fetal cardiac anatomy and function were measured and analyzed. Results GDM fetuses＇ cardiac ventricular walls were thicker than controls＇, and the differences between DM1 and DM2 were not significant except for end-diastolic left ventricular walls. In both GDM groups, the aortic flow velocities increased earlier than pulmonary artery and DM1 fetuses changed earlier than DM2 ones. GDM fetuses＇ left atrial shortening fraction was smaller than the controls＇ in the period of ≥34 weeks and negatively correlated with thicknesses of left ventricular walls and interventricular septum in DM1 fetuses （r=-0.438 and -0.506）. The right ventricular diastolic function in DM1 and DM2 fetuses decreased after the period of 28-34 weeks and in the period of ≥34 weeks respectively. Tel index of both left and right ventricles increased in DM1 group after the period of 〈28 weeks and in DM2 group only in the period of ≥ 34 weeks, with no significant differences between DM1 and DM2 groups in this period. Conclusion Fetuses of GDM mothers showed cardiac function impairments. Good maternal glycemic control may delay the impairments, but cannot reduce the degree. Some cardiac changes in GDM fetuses were similar to those in pregestational diabetic pregnancies except for several parameters and their changing time.展开更多
文摘目的:探讨Tei指数对于法洛氏四联症(tetralogy of Fallot,TOF)患儿术后的临床价值。方法:自2008年10月至2012年6月间来我院就诊的TOF患儿45例,术后先行超声Tei检测,根据结果分为3组,A组:Tei指数<0.5,B组:0.5≤Tei指数<0.7,C组:Tei指数≥0.7。行超声心动图检查测量左室射血分数(ejection fraction,EF)、计算右心Tei指数、记录呼吸机辅助时间、重症监护室监护时间、正性药物辅助时间、引流量。结果:A组与B组、C组患儿在呼吸机辅助时间、重症监护室监护时间、正性药物辅助时间、引流量等方面差异具有统计学意义。Tei指数与之具有负相关关系,EF在3组中差异无统计学意义。结论:Tei指数可以较敏感准确地反映TOF患儿右室功能的变化,是一个简单且有价值的临床指标。
基金supported by the National Natural Science Foundation of China (81001228)National High Technology Research and Development Program of China (863 Program)(2007AA02Z442)
文摘Objective To evaluate the fetal cardiac function in gestational diabetes mellitus （GDM） pregnancies under different maternal glycemic controls. Methods Forty four GDM mothers received 78 fetal echocardiographic evaluations at three gestational periods （〈28, 28-34 and ≥34 weeks） and were divided into poorly-（DM1） and well-（DM2） controlled groups according to their glycemic control at examination. Seventy uncomplicated mothers were selected as controls. Parameters of fetal cardiac anatomy and function were measured and analyzed. Results GDM fetuses＇ cardiac ventricular walls were thicker than controls＇, and the differences between DM1 and DM2 were not significant except for end-diastolic left ventricular walls. In both GDM groups, the aortic flow velocities increased earlier than pulmonary artery and DM1 fetuses changed earlier than DM2 ones. GDM fetuses＇ left atrial shortening fraction was smaller than the controls＇ in the period of ≥34 weeks and negatively correlated with thicknesses of left ventricular walls and interventricular septum in DM1 fetuses （r=-0.438 and -0.506）. The right ventricular diastolic function in DM1 and DM2 fetuses decreased after the period of 28-34 weeks and in the period of ≥34 weeks respectively. Tel index of both left and right ventricles increased in DM1 group after the period of 〈28 weeks and in DM2 group only in the period of ≥ 34 weeks, with no significant differences between DM1 and DM2 groups in this period. Conclusion Fetuses of GDM mothers showed cardiac function impairments. Good maternal glycemic control may delay the impairments, but cannot reduce the degree. Some cardiac changes in GDM fetuses were similar to those in pregestational diabetic pregnancies except for several parameters and their changing time.
