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Dynamic Simulation and Test Verifcation of Hydraulic Automatic Tensioner for an Engine Timing Chain Drive System
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作者 Zengming Feng Jinxing Yang Fei Wang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第5期291-303,共13页
As a fundamental component of an automobile engine’s timing chain drive system, the hydraulic automatic tensioner signifcantly enhances fuel economy while minimizing system vibrations and noise. However, there is a n... As a fundamental component of an automobile engine’s timing chain drive system, the hydraulic automatic tensioner signifcantly enhances fuel economy while minimizing system vibrations and noise. However, there is a noticeable lack of research on automatic hydraulic tensioners. This study presents a comprehensive calculation approach for the principal parameters of a hydraulic automatic tensioner. An efective method, grounded in hydraulics and multibody dynamics, was introduced for estimating the dynamic response of such a tensioner. The simulation model developed for the hydraulic tensioner is characterized by its rapid dynamic response, consistent operation, and high accuracy. The dynamic behavior of the tensioner was analyzed under varying boundary conditions, using sinusoidal signal excitation. It was observed that the maximum damping force increases with a decreasing leakage gap. Conversely, an increase in oil temperature or air content leads to a decrease in the maximum damping force. The reaction forces derived from these calculations align well with experimental results. This calculation and simulation approach ofers considerable value for the design of innovative hydraulic tensioners. It not only streamlines the design phase, minimizes the number of trials, and reduces product costs, but also provides robust insights for evaluating the performance of hydraulic tensioners. 展开更多
关键词 Hydraulic automatic tensioner Timing chain Leakage gap Hysteresis curve
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Hydrodynamic Response of A Fully Coupled TLP Hull-TTR System with Detailed Modeling of A Hydraulic Pneumatic Tensioner and Riser Joints
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作者 HAO Shuai YU Yang +2 位作者 YU Jian-xing YUAN Zhi-ming XU Li-xin 《China Ocean Engineering》 SCIE EI CSCD 2022年第3期451-463,共13页
Tension Leg Platform(TLP)in deepwater oil and gas field development usually consists of a hull,tendons,and top tension risers(TTRs).To maintain its top tension,each TTR is connected with a tensioner system to the hull... Tension Leg Platform(TLP)in deepwater oil and gas field development usually consists of a hull,tendons,and top tension risers(TTRs).To maintain its top tension,each TTR is connected with a tensioner system to the hull.Owing to the complicated configuration of the tensioners,the hull and TTRs form a strong coupled system.Traditionally,some simplified tensioner models are applied to analyze the TLP structures.There is a large discrepancy between their analysis results and the actual mechanism behaviors of a tensioner.It is very necessary to develop a more detailed tensioner model to consider the coupling effects between TLP and TTRs.In the present study,a fully coupled TLP hull-TTR system for hydrodynamic numerical simulation is established.A specific hydraulic pneumatic tensioner is modeled by considering 4 cylinders.The production TTR model is stacked up by specific riser joints.The simulation is also extended to analyze an array of TTRs.Different regular and irregular waves are considered.The behaviors of different cylinders are presented.The results show that it is important to consider the specific configurations of the tensioner and TTRs,which may lead to obviously different response behaviors,compared with those from a simplified model. 展开更多
关键词 top tension riser(TTR) fully coupled hull-tendon-TTR-tensioner model hydraulic pneumatic tensioner hydrodynamic response 3D potential flow theory
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Tensioner Vibration and Belt Slipping Behavior Investigation for Damped Serpentine Belt Drive Systems
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作者 王红云 上官文斌 《Journal of Beijing Institute of Technology》 EI CAS 2010年第1期25-30,共6页
A nonlinear rotational motion model for n-pulley damped serpentine belt drive systems (SBDSs) was developed.The effects of the belt deflection along the contact arc of pulleys on the belt span tensions were consider... A nonlinear rotational motion model for n-pulley damped serpentine belt drive systems (SBDSs) was developed.The effects of the belt deflection along the contact arc of pulleys on the belt span tensions were considered.The methods for calculating the tensioner arm vibration and belt slipping on pulleys were introduced.The effects of belt damping on rotational vibration of tensioner arm and belt slipping on pulleys were studied.Numerical solutions for a 3-pulley SBDS indicate that the belt slipping at the steady states should be controlled to avoid belt slipping at transient states.The slip factors tend to decrease when the belt damping increases,and the possibility of the belt slipping can be controlled through adjusting the wrap angles of pulleys and the preload of the tensioner when the design parameters of SBDS remain constant. 展开更多
关键词 serpentine belt drive system tensioner arm vibration belt slipping behavior numerical calculation
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Neurophysiological, histological, and behavioral characterization of animal models of distraction spinal cord injury: a systematic review 被引量:1
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作者 Bo Han Weishi Liang +4 位作者 Yong Hai Duan Sun Hongtao Ding Yihan Yang Peng Yin 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第3期563-570,共8页
Distraction spinal cord injury is caused by some degree of distraction or longitudinal tension on the spinal cord and commonly occurs in patients who undergo corrective operation for severe spinal deformity.With the i... Distraction spinal cord injury is caused by some degree of distraction or longitudinal tension on the spinal cord and commonly occurs in patients who undergo corrective operation for severe spinal deformity.With the increased degree and duration of distraction,spinal cord injuries become more serious in terms of their neurophysiology,histology,and behavior.Very few studies have been published on the specific characteristics of distraction spinal cord injury.In this study,we systematically review 22 related studies involving animal models of distraction spinal cord injury,focusing particularly on the neurophysiological,histological,and behavioral characteristics of this disease.In addition,we summarize the mechanisms underlying primary and secondary injuries caused by distraction spinal cord injury and clarify the effects of different degrees and durations of distraction on the primary injuries associated with spinal cord injury.We provide new concepts for the establishment of a model of distraction spinal cord injury and related basic research,and provide reference guidelines for the clinical diagnosis and treatment of this disease. 展开更多
关键词 animal models behavior DISTRACTION heterogeneity HISTOLOGY mechanism NEUROPHYSIOLOGY spinal cord injury systematic review tension
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Research on Anti-Fluctuation Control of Winding Tension System Based on Feedforward Compensation
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作者 Yujie Duan Jianguo Liang +4 位作者 Jianglin Liu Haifeng Gao Yinhui Li Jinzhu Zhang Xinyu Wen 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1239-1261,共23页
In the fiber winding process,strong disturbance,uncertainty,strong coupling,and fiber friction complicate the winding constant tension control.In order to effectively reduce the influence of these problems on the tens... In the fiber winding process,strong disturbance,uncertainty,strong coupling,and fiber friction complicate the winding constant tension control.In order to effectively reduce the influence of these problems on the tension output,this paper proposed a tension fluctuation rejection strategy based on feedforward compensation.In addition to the bias harmonic curve of the unknown state,the tension fluctuation also contains the influence of bounded noise.A tension fluctuation observer(TFO)is designed to cancel the uncertain periodic signal,in which the frequency generator is used to estimate the critical parameter information.Then,the fluctuation signal is reconstructed by a third-order auxiliary filter.The estimated signal feedforward compensates for the actual tension fluctuation.Furthermore,a time-varying parameters fractional-order PID controller(TPFOPID)is realized to attenuate the bounded noise in the fluctuation.Finally,TPFOPID is enhanced by TFO and applied to control a tension control system considering multi-source disturbances.The stability of the method is analyzed by using the Lyapunov theorem.Finally,numerical simulations verify that the proposed scheme improves the tracking ability and robustness of the system in response to tension fluctuations. 展开更多
关键词 Constant tension control anti-fluctuation strategy tension fluctuation observer time-varying parameters fractional-order PID controller feedforward compensate
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Atomistic evaluation of tension–compression asymmetry in nanoscale body-centered-cubic AlCrFeCoNi high-entropy alloy
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作者 邢润龙 刘雪鹏 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期613-622,共10页
The tension and compression of face-centered-cubic high-entropy alloy(HEA) nanowires are significantly asymmetric, but the tension–compression asymmetry in nanoscale body-centered-cubic(BCC) HEAs is still unclear. In... The tension and compression of face-centered-cubic high-entropy alloy(HEA) nanowires are significantly asymmetric, but the tension–compression asymmetry in nanoscale body-centered-cubic(BCC) HEAs is still unclear. In this study,the tension–compression asymmetry of the BCC Al Cr Fe Co Ni HEA nanowire is investigated using molecular dynamics simulations. The results show a significant asymmetry in both the yield and flow stresses, with BCC HEA nanowire stronger under compression than under tension. The strength asymmetry originates from the completely different deformation mechanisms in tension and compression. In compression, atomic amorphization dominates plastic deformation and contributes to the strengthening, while in tension, deformation twinning prevails and weakens the HEA nanowire.The tension–compression asymmetry exhibits a clear trend of increasing with the increasing nanowire cross-sectional edge length and decreasing temperature. In particular, the compressive strengths along the [001] and [111] crystallographic orientations are stronger than the tensile counterparts, while the [110] crystallographic orientation shows the exactly opposite trend. The dependences of tension–compression asymmetry on the cross-sectional edge length, crystallographic orientation,and temperature are explained in terms of the deformation behavior of HEA nanowire as well as its variations caused by the change in these influential factors. These findings may deepen our understanding of the tension–compression asymmetry of the BCC HEA nanowires. 展开更多
关键词 high-entropy alloys body-centered-cubic NANOWIRE tension–compression asymmetry atomistic simulations
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Geometry and formation mechanism of tension gashes and their implication on the hydrocarbon accumulation in the deep-seated strata of sedimentary basin:A case from Shunnan area of Tarim Basin
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作者 Yan-Nan Du Kong-You Wu +4 位作者 Yin Liu Yan-Ying Li Zi-Cheng Cao You-Wei Cui Jun Liu 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期87-99,共13页
With the theoretical and technological developments related to cratonic strike-slip faults,the Shuntuoguole Low Uplift in the Tarim Basin has attracted considerable attention recently.Affected by multi-stage tectonic ... With the theoretical and technological developments related to cratonic strike-slip faults,the Shuntuoguole Low Uplift in the Tarim Basin has attracted considerable attention recently.Affected by multi-stage tectonic movements,the strike-slip faults have controlled the distribution of hydrocarbon resources owing to the special fault characteristics and fault-related structures.In contrast,the kinematics and formation mechanism of strike-slip faults in buried sedimentary basins are difficult to investigate,limiting the discussion of these faults and hydrocarbon accumulation.In this study,we identified the characteristics of massive sigmoidal tension gashes(STGs)that formed in the Shunnan area of the Tarim Basin.High-resolution three-dimensional seismic data and attribute analyses were used to investigate their geometric and kinematic characteristics.Then,the stress state of each point of the STGs was calculated using seismic curvature attributes.Finally,the formation mechanism of the STGs and their roles in controlling hydrocarbon migration and accumulation were discussed.The results suggest that:(1)the STGs developed in the Shunnan area have a wide distribution,with a tensile fault arranged in an enéchelon pattern,showing an S-shaped bending.These STGs formed in multiple stages,and differential rotation occurred along the direction of strike-slip stress during formation.(2)Near the principal displacement zone of the strike-slip faults,the stress value of the STGs was higher,gradually decreasing at both ends.The shallow layer deformation was greater than the deep layer deformation.(3)STGs are critical for connecting source rocks,migrating oil and gas,sealing horizontally,and developing efficient reservoirs.This study not only provides seismic evidence for the formation and evolution of super large STGs,but also provides certain guidance for oil and gas exploration in this area. 展开更多
关键词 Tarim Basin Sigmoidal tension gashes Seismic attributes Shear stress calculation Formation mechanism Reservoir control
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Effects of Atmospheric Pressure on Developmental Characteristics and the Stability of Air Entraining Agent for Concrete
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作者 李立辉 牛开民 +3 位作者 TIAN Bo CHEN Xin FU Ziqian ZHU Xuwei 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第4期979-989,共11页
In order to ascertain the effects of atmospheric pressure on developmental characteristics and the stability of AEA(air-entraining agent)solution bubbles,AEA solution experiments and AEA solution bubble experiments we... In order to ascertain the effects of atmospheric pressure on developmental characteristics and the stability of AEA(air-entraining agent)solution bubbles,AEA solution experiments and AEA solution bubble experiments were,respectively,conducted in Peking(50 m,101.2 kPa)and Lhasa(3,650 m,63.1 kPa).Surface tensions and inflection-point concentrations were tested based on AEA solutions,whilst developmental characteristics,thicknesses and elastic coefficients of liquid films were tested based on air bubbles of AEA solutions.The study involved three types of AEAs,which were TM-O,226A,and 226S.The experimental results show that initial sizes of TM-O,226A,and 226S are,respectively,increased by 43.5%,17.5%,and 3.8%.With the decrease of ambient pressure,the drainage rate and the drainage index of AEA solution bubbles increase.Interference experiments show that the liquid film thicknesses of all tested AEA solution bubbles are in micron scales.When the atmospheric pressure decreases from 101.2 to 63.1 kPa,the liquid film thicknesses of three types of AEA solutions decrease in various degrees;and film elasticities at critical thicknesses increase.Liquid film of 226S solution bubbles is the most stable,presenting as a minimum thickness variation.It should be noted that elastic coefficient of liquid film only represents the level at critical thickness,thus it can not be applied as the only evaluating indicator of bubble stability.For a type of AEA,factors affecting the stability of its bubbles under low atmospheric pressure include initial bubbles size,liquid film thickness,liquid film elasticity,ambient temperature,etc. 展开更多
关键词 air-entraining agent surface tension bubble size liquid film thickness liquid film elasticity atmospheric pressure
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Bulging Distortion of Austenitic Stainless Steel Sheet on the Partially Penetrated Side of Non-Penetration Lap Laser Welding Joint
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作者 Chengwu Yao Enze Liu +1 位作者 Jiaming Ni Binying Nie 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期286-295,共10页
Non-penetration laser welding of lap joints in austenitic stainless steel sheets is commonly preferred in fields where the surface quality is of utmost importance.However,the application of non-penetration welded aust... Non-penetration laser welding of lap joints in austenitic stainless steel sheets is commonly preferred in fields where the surface quality is of utmost importance.However,the application of non-penetration welded austenitic stainless steel parts is limited owing to the micro bulging distortion that occurs on the back surface of the partial penetration side.In this paper,non-penetration lap laser welding experiments,were conducted on galvanized and SUS304 austenitic stainless steel plates using a fiber laser,to investigate the mechanism of bulging distortion.A comparative experiment of DC01 galvanized steel-Q235 carbon steel lap laser welding was carried out,and the deflection and distortion profile of partially penetrated side of the sheets were measured using a noncontact laser interferometer.In addition,the cold-rolled SUS304 was subjected to heat holding at different temperatures and water quenching after bending to characterize its microstructure under tensile and compressive stress.The results show that,during the heating stage of the thermal cycle of laser lap welding,the partial penetration side of the SUS304 steel sheet generates compressive stress,which extrudes the material in the heat-affected zone to the outside of the back of the SUS304 steel sheet,thereby forming a bulge.The findings of these experiments can be of great value for controlling the distortion of the partial penetrated side of austenitic stainless steel sheet during laser non-penetration lap welding. 展开更多
关键词 Non-penetration lap laser welding Bulging distortion Austenitic stainless steel Compressive stress Tension stress
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Mechanical behavior of rock under uniaxial tension:Insights from energy storage and dissipation
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作者 Guanshuang Tan Chunde Ma +3 位作者 Junjie Zhang Wenyuan Yang Guiyin Zhang Zihao Kang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第7期2466-2481,共16页
Many rock engineering projects show that the growth of tensile cracks is often an important cause of engineering disasters,and the mechanical behavior of rocks is essentially the transmission,storage,dissipation and r... Many rock engineering projects show that the growth of tensile cracks is often an important cause of engineering disasters,and the mechanical behavior of rocks is essentially the transmission,storage,dissipation and release of energy.To investigate the tensile behavior of rock from the perspective of energy,uniaxial tension tests(UTTs)and uniaxial compression tests(UCTs)were carried out on three typical rocks(granite,sandstone and marble).Different unloading points were set before the peak stress to separate elastic energy and dissipated energy.The input energy density ut,elastic energy density ue,and dissipated energy density ud at each unloading point were calculated by integrating stress-strain curves.The results show that there is a strong linear relationship between the three energy parameters and the square of the unloading stress in UCT,but this linear relationship is weaker in UTT.The ue and ud increase linearly with the increase in ut in UCT and UTT.Based on the phenomenon that ue and ud increase linearly with ut,the applicability of Wp et index in UTT was proved and the relative energy storage capacity and absolute energy distribution characteristics of three rocks in UCT and UTT were evaluated.The tensile behavior of marble and sandstone in UTT can be divided into two stages vaguely according to the energy distribution,but granite is not the case.In addition,based on dissipated energy,the damage evolution of three types of rocks in UCT and UTT was discussed.This study provides some new insights for understanding the tensile behavior of rock. 展开更多
关键词 Uniaxial tension Energy density Mechanical behavior Energy storage coefficient Energy dissipation coefficient
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Near resonance vibration isolation on a levered-dual response(LEDAR)Coulomb-damped system by differential preloads/offsets in linear springs
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作者 T.I.TOLUWALOJU C.K.THEIN D.HALIM 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第6期1033-1050,共18页
The levered-dual response(LEDAR)Coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear springs.It takes the advantages of both the preloads/offsets in linear springs... The levered-dual response(LEDAR)Coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear springs.It takes the advantages of both the preloads/offsets in linear springs and the guiderail friction for realizing different levels of vibration isolation.The isolation capacities are investigated on the strategies with both the horizontal and vertical guiderails,with the horizontal rail only,and without guiderails.The compressive preloads generally result in the consumption of most of the initial excitation energy so as to overcome the potential threshold.The isolation onsets at the frequency ratio of 1∓0.095 on the left-hand side(LHS)and the right-hand side(RHS)of the lever are relative to the load plate connector.The observed near resonant isolation thus makes the LEDAR system a candidate for the isolation of the mechanical systems about resonance while opening a path for simultaneous harvesterisolation functions and passive functions at extreme frequencies. 展开更多
关键词 lever ratio Coulomb damping preload tension/compression isolation band/depth offset potential
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聚酯缆动力学行为计算方法研究
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作者 康庄 隋海波 +1 位作者 艾尚茂 张岩松 《哈尔滨工程大学学报(英文版)》 CSCD 2024年第2期398-405,共8页
The dynamic stiffness of polyester rope presents a complex mechanical performance,and the search for an appropriate calculation method to simulate this property is important.Distorted simulation results eventually yie... The dynamic stiffness of polyester rope presents a complex mechanical performance,and the search for an appropriate calculation method to simulate this property is important.Distorted simulation results eventually yield inaccurate line tension and vessel offset predictions,with the inaccuracy of vessel offset being particularly large.This paper proposes a flexible calculation method for the dynamic behavior of polyester rope based on the dynamic stiffness model.A real-time varying stiffness model of polyester rope is employed to simulate tension response through rope strain monitoring.Consequently,a simulation program is developed,and related case studies are conducted to explore the differences between the proposed method and analytical procedure of the DNV standard.Orcaflex is used to simulate the results of the latter procedure for comparison.Results show the convenience and straightforwardness of the procedure in the selection of an approximate dynamic stiffness model for polyester rope,which leads to an engineering-oriented approach.However,the proposed method is related to line property,which can directly reflect the dynamic behavior of polyester rope.Thus,a flexible calculation method may provide a reference for the simulation of the dynamic response of polyester mooring systems. 展开更多
关键词 Polyester rope Dynamic stiffness model Mean tension Minimum breaking strength Case studies
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Static-to-kinematic modeling and experimental validation of tendon-driven quasi continuum manipulators with nonconstant subsegment stiffness
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作者 郑先杰 丁萌 +2 位作者 刘辽雪 王璐 郭毓 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期316-326,共11页
Continuum robots with high flexibility and compliance have the capability to operate in confined and cluttered environments. To enhance the load capacity while maintaining robot dexterity, we propose a novel non-const... Continuum robots with high flexibility and compliance have the capability to operate in confined and cluttered environments. To enhance the load capacity while maintaining robot dexterity, we propose a novel non-constant subsegment stiffness structure for tendon-driven quasi continuum robots(TDQCRs) comprising rigid-flexible coupling subsegments.Aiming at real-time control applications, we present a novel static-to-kinematic modeling approach to gain a comprehensive understanding of the TDQCR model. The analytical subsegment-based kinematics for the multisection manipulator is derived based on screw theory and product of exponentials formula, and the static model considering gravity loading,actuation loading, and robot constitutive laws is established. Additionally, the effect of tension attenuation caused by routing channel friction is considered in the robot statics, resulting in improved model accuracy. The root-mean-square error between the outputs of the static model and the experimental system is less than 1.63% of the arm length(0.5 m). By employing the proposed static model, a mapping of bending angles between the configuration space and the subsegment space is established. Furthermore, motion control experiments are conducted on our TDQCR system, and the results demonstrate the effectiveness of the static-to-kinematic model. 展开更多
关键词 static-to-kinematic modeling scheme tendon-driven quasi continuum robot nonconstant subsegment stiffness tension attenuation effect
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Effectivity and safety of trifocal intraocular lenses and capsular tension rings implantation for cataract patients with axial high myopia
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作者 Shan Hua Qiu-Xia Xie +1 位作者 Hu Wang Jing-Xiang Zhong 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期499-508,共10页
●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical tria... ●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical trial was conducted.Totally 98 eyes(74 patients)who underwent femtosecond laser-assisted cataract surgery(FLACS)with trifocal IOLs were enrolled in the study and followed up for 2y after surgery:46 eyes(33 patients)with capsular tension ring implantation in the long axial lengths(AL)group(26<AL<29 mm)and 52 eyes(41 patients)in the normal AL group(22<AL<24.5 mm).Postoperative outcomes about effectivity and safety,including the subjective and objective visual quality,and postoperative complications were assessed.●RESULTS:Uncorrected distance visual acuity at 5 m and uncorrected intermediate visual acuity at 60 and 80 cm in the long AL group were significantly worse than those in the normal AL group at 3mo postoperatively(P<0.05).The differences in reading speed,spectacle independence and potential visual complaints between the two groups were not statistically significant(P>0.05).The dysfunctional lens index and total modulation transfer function(MTF)average height were similar between the two groups.The postoperative internal coma aberrations in the axial high myopia eyes were significantly higher than that in the normal AL group(P<0.05).The total satisfaction score in the long AL group(91.32±2.76)was slightly higher than that in the normal AL group(90.36±3.47),but there was no difference(P=0.136).A statistically negative correlation was found between corrected distance visual acuity(CDVA)and dysfunctional lens index(r=-0.382,P=0.009),and between CDVA and the total MTF average height(r=-0.374,P=0.01).But there was no significant correlation between CDVA and total satisfaction score(r=0.059,P=0.696).Postoperative complications mainly presented as posterior capsular opacity(PCO),retinal detachment and cystoid macular edema.There was no difference in the incidence of fundus disease(6.5%vs 3.8%,P=0.663)or PCO(17.4%vs 7.7%,P=0.217)between the two groups at two years.●CONCLUSION:The utilization of trifocal IOL and capsular tension ring implantation is beneficial for cataract patients with axial high myopia undergoing FLACS.This approach not only ensures excellent subjective feelings and objective visual quality,but also does not increase the incidence of postoperative complications. 展开更多
关键词 trifocal intraocular lenses capsular tension ring axial high myopia CATARACT visual quality
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Neuroimaging in atypical normal tension glaucoma:debating routine implementation in the absence of classic neurological findings
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作者 Umay Güvenç Gülizar Demirok +1 位作者 Güner Üney Selma Uzman 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期509-517,共9页
●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was... ●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was conducted on 90 atypical NTG patients who underwent cranial magnetic resonance imaging(MRI)due to atypical symptoms.The demographic characteristics,clinical parameters,and radiological findings were recorded.●RESULTS:Among the patients,66.7%had abnormal radiology results,with the most common findings being gliosis(34.4%),sequelae of cerebrovascular events and vascular malformations(14.4%),and benign intracranial mass lesions(11%).Non-glaucomatous visual field defects were more frequently observed in patients with abnormal neuroimaging results.However,there were no significant differences in intraocular pressure,optic disc parameters,retinal nerve fiber layer thickness,and visual field indices between patients with normal and abnormal radiological results.The mean age of the patients was 58.74y.Interestingly,there was a significant age difference,with the abnormal radiology group having a higher median age(P=0.021).●CONCLUSION:The study highlights the importance of cranial imaging in older NTG patients to detect underlying pathologies and prevent misdiagnosis.It suggests that neuroimaging may be warranted in NTG patients with atypical visual field defects incompatible with glaucoma.However,routine neuroimaging in all NTG patients without classic neurological signs may not be necessary. 展开更多
关键词 normal tension glaucoma NEUROIMAGING atypical visual field defects
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Unveiling the silent link:Normal-tension glaucoma's enigmatic bond with cardiac blood flow
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作者 Prasanna Venkatesh Ramesh Arvind Kumar Morya +5 位作者 Ajanya K Aradhya Pavithra Pannerselvam Sai Thaejesvi Gopalakrishnan Shruthy Vaishali Ramesh Aji Kunnath Devadas Navaneeth Krishna 《World Journal of Cardiology》 2024年第1期10-15,共6页
This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,ch... This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,characterized by optic nerve damage and visual field loss despite normal intraocular pressure,has long puzzled clinicians.One emerging perspective suggests that alterations in ocular blood flow,particularly within the optic nerve head,may play a pivotal role in its pathogenesis.While NTG shares commonalities with its high-tension counterpart,its unique pathogenesis and potential ties to cardiovascular health make it a fascinating subject of exploration.It navigates through the complex web of vascular dysregulation,blood pressure and perfusion pressure,neurovascular coupling,and oxidative stress,seeking to uncover the hidden threads that tie the heart and eyes together in NTG.This review explores into the intricate mechanisms connecting cardiovascular factors to NTG,shedding light on how cardiac dynamics can influence ocular health,particularly in cases where intraocular pressure remains within the normal range.NTG's enigmatic nature,often characterized by seemingly contradictory risk factors and clinical profiles,underscores the need for a holistic approach to patient care.Drawing parallels to cardiac health,we examine into the shared vascular terrain connecting the heart and the eyes.Cardiovascular factors,including systemic blood flow,endothelial dysfunction,and microcirculatory anomalies,may exert a profound influence on ocular perfusion,impacting the delicate balance within the optic nerve head.By elucidating the subtle clues and potential associations between cardiology and NTG,this review invites clinicians to consider a broader perspective in their evaluation and management of this elusive condition.As the understanding of these connections evolves,so too may the prospects for early diagnosis and tailored interventions,ultimately enhancing the quality of life for those living with NTG. 展开更多
关键词 Normal tension glaucoma Vascular dysregulation Ocular blood flow Blood pressure Perfusion pressure Oxidative stress
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Understanding wound healing in obesity
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作者 Asha Cotterell Michelle Griffin +3 位作者 Mauricio A Downer Jennifer B Parker Derrick Wan Michael T Longaker 《World Journal of Experimental Medicine》 2024年第1期22-32,共11页
Obesity has become more prevalent in the global population.It is associated with the development of several diseases including diabetes mellitus,coronary heart disease,and metabolic syndrome.There are a multitude of f... Obesity has become more prevalent in the global population.It is associated with the development of several diseases including diabetes mellitus,coronary heart disease,and metabolic syndrome.There are a multitude of factors impacted by obesity that may contribute to poor wound healing outcomes.With millions worldwide classified as obese,it is imperative to understand wound healing in these patients.Despite advances in the understanding of wound healing in both healthy and diabetic populations,much is unknown about wound healing in obese patients.This review examines the impact of obesity on wound healing and several animal models that may be used to broaden our understanding in this area.As a growing portion of the population identifies as obese,understanding the underlying mechanisms and how to overcome poor wound healing is of the utmost importance. 展开更多
关键词 OBESITY Wound healing ADIPOKINES Tissue fibrosis Diabetes Preclinical animal models Hypertrophic skin scarring Wound tension Metabolic syndrome
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Eudragit®-PEG Nanoparticles: Physicochemical Characterization and Interfacial Tension Measurements
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作者 Papa Mady Sy Sidy Mouhamed Dieng +4 位作者 Alphonse Rodrigue Djiboune Louis Augustin Diaga Diouf Boucar Ndong Gora Mbaye Mounibé Diarra 《Open Journal of Biophysics》 2024年第2期121-131,共11页
The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potent... The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potentials were studied and compared at a water/cyclohexane model interface using a droplet tensiometer (Tracker Teclis, Longessaigne, France). The progressive interfacial adsorption of the NPs in the aqueous phase was monitored by tensiometry. The model interface was maintained and observed in a drop tensiometer, analyzed via axisymmetric drop shape analysis (ADSA), to determine the interfacial properties. Given the direct relationship between the stability of Pickering emulsions (emulsions stabilized by solid nanoparticles) and the interfacial properties of these layers, different nanoparticle systems were compared. Specifically, Eudragit NPs of different sizes were examined. Moreover, the reduction of the Zeta potential with PEG-6000 induces partial aggregation of the NPs (referred to as NP flocs), significantly impacting the stability of the interfacial layer. Dynamic surface tension measurements indicate a significant decrease in interfacial tension with Eudragit® nanoparticles (NPs). This reduction correlates with the size of the NPs, highlighting that this parameter does not operate in isolation. Other factors, such as the contact angle and wettability of the nanoparticles, also play a critical role. Notably, larger NPs further diminished the interfacial tension. This study enhances our understanding of the stability of Pickering emulsions stabilized by Eudragit® L100 polymeric nanoparticles. 展开更多
关键词 NANOPARTICLES Eudragit® PEG Interfacial Tension Pickering Emulsion
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Impact of Tension-Type Headaches in the Workplace in Brazzaville
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作者 Happhia Dinah Boubayi Motoula Latou Josué Euberma Diatewa +4 位作者 Ghislain Armel Mpandzou Prince Eliot Galieni Sounga Bandzouzi Jean Brice Mouendenguia Karen Lise Obondzo Aloba Paul Macaire Ossou-Nguiet 《Neuroscience & Medicine》 2024年第2期77-91,共15页
Introduction: Tension-type headaches are the most widespread of the primary headache disorders. Due to their high prevalence, tension-type headaches represent a major public health problem with an enormous socio-econo... Introduction: Tension-type headaches are the most widespread of the primary headache disorders. Due to their high prevalence, tension-type headaches represent a major public health problem with an enormous socio-economic burden. Determining their impact remains a challenge. Objective: To assess the impact of occupational tension-type headache in Brazzaville and identify associated factors. Population and Methods: This was an analytical case-control study conducted in public and private companies in the city of Brazzaville over a period of four (04) months. The case population consisted of cephalalgic employees;the control population was drawn from the same companies and was free of tension-type headaches. Study variables were divided into socio-professional, clinical and individual impact variables. Individual impact variables were represented by: the HIT-6 score, which incorporates a very broad conception of disability, covering several domains, namely: severity of pain during attacks and the restrictive and limiting nature of attacks. Results: Individual impact was severe in 18 (62.1%) men and 11 (37.9%) women. Mean age was 36.3 6.14 years for cases with severe impact. The mean duration of headache was 40.3 32.7 months for cases with severe impact. Tension headache evolved in attacks in 22 (75.9%) cases with severe impact, and continuously in seven (24.1%) cases. The average number of attacks per month was 2.52 1.04 for cases with severe impact. Cases with severe impact included 14 (48.3%) with chronic headache and 15 (51.7%) with episodic headache. Pain of severe intensity present in 48.3% of cases was associated with a severe impact of tension-type headache: OR = 151.66 [2.36 - 44245.95] and p-value = 0.037. At least one days absence from work per year was observed in 47.4% of our cases. The number of days off work per year due to tension-type headache had an interquartile range between 0 and 3 days and extremes from 0 to 14 days. It was the consequence of a severe impact on daily and/or professional activities. Conclusion: The high frequency of tension-type headaches in the workplace and its impact on the condition of workers in Brazzaville represent a real public health problem. It was found that the number of days absent from work per year due to tension headaches was the consequence of a severe impact on daily and/or professional activities. An awareness-raising program in this environment seems necessary, as well as an assessment of working conditions. 展开更多
关键词 IMPACT Tension Headache WORKPLACE
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The Tension Cosmology, Largest Cosmic Structures and Explosions of Supernovae from SST
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作者 Sylwester Kornowski 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2024年第3期1029-1044,共16页
Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter lea... Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter leads to the disagreement in the galaxy clustering amplitude, quantified by the parameter S8. Within the same model we described the Hubble tension. We described also the mechanism that transforms the gravitational collapse into an explosion—it concerns the dynamics of virtual fields that lead to dark energy. Our calculations concern the Type Ia supernovae and the core-collapse supernovae. We calculated the quantized masses of the progenitors of supernovae, emitted total energy during explosion, and we calculated how much of the released energy was transferred to neutrinos. Value of the speed of sound in the strongly interacting matter measured at the LHC confirms that presented here model is correct. Our calculations show that the Universe is cyclic. 展开更多
关键词 Scale-Symmetric Theory Tension Cosmology Coupling Constants Parameters σ8 and S8 Largest Cosmic Structures Dark Energy Supernova Explosion Cyclic Universe
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