Establishment of Microbial Limit Test Methods for Two Hospital Preparations

[Objectives] This study was conducted to establish microbial limit test methods for traditional Chinese medicine preparations Yunpi Granules and Bupi Qiangli Paste. [Methods] According to General Rules of Part IV of Chinese Pharmacopoeia, applicability tests were conducted on microbial limit test methods for the above two traditional Chinese medicine preparations by the plate method. [Results] The established methods showed recovery values in the range of 0.5-2.0 for both experimental strains, and the control bacteria could be detected in the experimental group, but not in the negative control group. [Conclusions] The microbial limit test methods were reliable for the two traditional Chinese medicine preparations and could be used for quality control.

Discussion on pile axial load test methods and their applicability in cold regions

The measurement of pile axial load is of great significance to determining pile foundation design parameters such as skin friction and end bearing capacity and analyzing load transfer mechanisms.Affected by the temperature and ice content of frozen ground,the interface contact relationship between pile foundation and frozen soil is complicated,making pile axial load measurements more uncertain than that in non-frozen ground.Therefore,it is necessary to gain an in-depth understanding of the current pile axial load test methods.Four methods are systematically reviewed:vibrating wire sensors,strain gauges,sliding micrometers,and optical fiber strain sensors.At the same time,the applicability of the four test methods in frozen soil regions is discussed in detail.The first two methods are mature and commonly used.The sliding micrometer is only suitable for short-term measurement.While the Fiber Bragg grating(FBG)strain gauge meets the monitoring requirements,the Brillouin optical time-domain reflectometer(BOTDR)needs further verification.This paper aims to provide a technical reference for selecting and applying different methods in the pile axial load test for the stability study and bearing capacity assessment of pile foundations in cold regions.

A review of welding residual stress test methods

Due to local uneven heating during the welding process,the residual stress of the structure after welding affects the reliability of it.In order to ensure the reliability,it is of great significance to test the residual stress distribution of the welded joint.It has always been the focus to find a simple and feasible method for residual stress testing to quickly and accurately obtain the residual stress distribution of welded joints.The mechanical measurement method has high measurement accuracy,convenient and easy operation,but it will cause certain damage to the components.Physical measurement method can avoid damage to components,but its test cost is usually high,and its measurement accuracy can also be affected by the material microstructure characteristics of welded components.Based on the advantages and disadvantages of these two residual stress test methods,a modal test method is proposed.This method is a non-destructive measurement method.Based on the mathematical relationship between the residual stress of the welded structure and the natural frequency(mathematical model),the natural frequency is measured through the modal test to calculate the residual stress quickly.However,it is difficult to establish a mathematical model with this method,and it is not suitable for realization.

A Review of Test Methods for the Determination of the Permeability Coefficient of Gravelly Soils Used for Embankment Dams

The factors influencing the permeability coefficient of gravelly soils used for the development of embankment dams(core wall)are analyzed.Such factors include(but are not limited to)soil size,anisotropy,density and boundary effects.A review of the literature is conducted and new directions of research are proposed.In such a framework,it is shown that gravelly soil with controlled density and vertical stress should be used to optimize the measurement of the vertical and horizontal permeability coefficients,respectively.

Dynamic test methods for natural frequency of footbridge

Using environmental random vibration as the excitation,traditional accelerometer method,non-contact video method and non-contact laser method were employed to determine the natural frequency of Kunyu River footbridge.All the results of these three methods are close to 2.70 Hz,which are concordant with each other and hence credible.

Validation of Microbial Limit Test Methods of Tongmai Tangyanming Capsule

[ Objectives] This study was conducted to establish a method for microbial limit test of Tongmai Tangyanming Capsule. [ Methods] According to the Chinese Pharmacopoei 2015 edition of the four general rules, the microbiological limits of non-sterile products were verified. [ Results] Tongmai Tangyanming Capsule has a strong inhibitory effect on Bacillus subtilis and Candida albicans. The antimicrobial activity was significantly eliminated after increasing the diluent （ 1 ： 20） ; and the recoveries were in the range of 0.5 -2 when the total quantities of aerobic microbes were determined by dilution method （1：20）. When the total quantities of mould and yeast were determined by dilution method （1：20）, the recoveries were from 0.5 to 2, and Escherichia coli, cholate-tolerant Gram-negative bacteria and Salmonella can be detected by the test solution dilution method. [ Condusions] With the plate method, the total quantities of aerobic bacteria and the quantities of mould and yeast were examined by increasing diluent, and conventional method was used for examination of control bacteria including E. coli, cholatetolerant Gram-negative bacteria and Salmonella. This method has been proved effective for microbial limit test of Tongmai Tangyanming Capsule, and can effectively control the quality of the preparation. The method is accurate and reliable.

Validation of Microbial Limit Test Methods of Compound Gangbangui Capsule

[Objectives] This study was conducted to establish a method for microbial limit test of Compound Gangbangui Capsule. [Methods] According to the Chinese Pharmacopoei 2015 edition of the four general rules,the microbiological limits of non-sterile products were verified. [Results]Compound Gangbangui Capsule has a strong inhibitory effect on S. aureus,and the antimicrobial activity was significantly eliminated after increasing the diluent（ 1∶ 20）; and the recoveries were in the range of 0. 5-2. 0 when the total quantities of aerobic microbes were determined by dilution method（ 1∶ 20）. When the total quantities of mould and yeast were determined by conventional method（ 1∶ 20）,the recoveries were from 0. 5 to 2. 0,and Escherichia coli can be detected in experimental groups by the test solution dilution method. [Conclusions]With the plate method,the total quantities of aerobic bacteria and the quantities of mould and yeast were examined by increasing diluent and conventional method,respectively,and control bacteria,E. coli was examined by conventional method. This method has been proved effective for microbial limit test of Compound Gangbangui Capsule,and can effectively control the quality of the preparation. The method is accurate and reliable.

Comparative study of flexural strength test methods on CAD/CAM Y-TZP dental ceramics

Clinically,fractures are the main cause of computer-aided design and computer-aided manufacturing(CAD/CAM)3 mol%-yttria-stabilized tetragonal zirconia polycrystal(Y-TZP)all-ceramic dental restorations failure because of repetitive occlusal loading.The goal of this work is to study the effect of test methods and specimen’s size on the flexural strength of five ceramic products.Both biaxial flexure test(BI)and uni-axial flexure tests(UNI),including three-point flexure test(3PF)and four-point flexure test(4PF),are used in this study.For all five products,the flexural strength is as follows:BI>3PF>4PF.Furthermore,specimens with smaller size(3PF-s)have higher values than the bigger ones(3PF).The difference between BI and UNI resulted from the edge flaws in ceramic specimens.The relationship between different UNI(including 3PF-s,3PF and 4PF)can be explained according to Weibull statistical fracture theory.BI is recommended to evaluate the flexural strength of CAD/CAM Y-TZP dental ceramics.

A Mini Review on Testing Methods for Mechanical Properties of Natural Fibre Honeycomb Sandwich Structure and Fractography Analysis

This paper is a review of the past research of mechanical testing methods for natural fibre honeycomb sandwich structure as well as failure modes analysis at a microscopic level by using Scanning Electron Microscope (SEM). As the world is garnering attention towards renewable resources for environmental purposes, studies of natural fibre have been increasing as well as the application of natural fibre throughout various industries such as aerospace, automobiles, and construction sectors. This paper is started with brief information regarding the honeycomb sandwich structure, introduction to natural fibre, its applications as well as the factors affecting the performances of the structure. Next, the mechanical testing methods are listed out as well as the expected outcomes obtained from the respective testing. The mechanical properties are also identified by conducting lab tests according to the ASTM standard for sandwich and core structures. The microstructure of the deformed samples is then examined under Scanning Electron Microscope (SEM) by using different magnifications to study the failure mechanisms of the samples. The images obtained from the SEM test are analyzed by using fractography which will show the failure modes of the samples. This article is based on past research conducted by professional on the related topic.

Testing methods for 1100 kV UHVDC transformer

1 Development of UHVDC transmission capabilities The economical development of China is closely connected with safe and reliable power supply.Load centers e.g.in central and eastern China need huge amounts of electrical power.Available energy resources and consumption areas are often distributed inverse.As a consequence it is necessary to import electrical power to load center areas in an economic and efficient way.

Provenance of Coloured Gemstones-Availability,Testing Methods,Future Trends

Gemstones have fascinated mankind forever,and people traveled far to find them.The Silk Road is one of the most traditional trade routes in the middle ages that was used to bring the precious stones to the European market.Later,emeralds from Colombia were shipped via the ocean to the Old World.

Application of the extended Fourier amplitude sensitivity testing(FAST)method to inflated,axial stretched,and residually stressed cylinders

This paper is dedicated to applying the Fourier amplitude sensitivity test(FAST)method to the problem of mixed extension and inflation of a circular cylindrical tube in the presence of residual stresses.The metafunctions and the Ishigami function are considered in the sensitivity analysis(SA).The effects of the input variables on the output variables are investigated,and the most important parameters of the system under the applied pressure and axial force such as the axial stretch and the azimuthal stretch are determined.

Analysis on Effectiveness of Testing and Evaluation of Bridge Repair and Reinforcement

Bridge engineering is an important part of basic engineering in today’s transportation field,and its quality and performance have a vital impact on the improvement and development of modern transportation engineering.With the continuous development of transportation engineering,the maintenance and reinforcement of existing bridges are also being given more emphasis.In order to scientifically evaluate the effectiveness of bridge maintenance and reinforcement,this paper analyzes its detection and evaluation,including the significance,key points,and main methods of detection and evaluation.Therefore,this analysis aim to provide some reference for the maintenance and reinforcement and the quality improvement of bridge engineering.

Importance,Organization and Evaluation of Interlaboratory Tests

The importance of ＂precise＂ test values and their verification is growing in every industry throughout the world, lnterlaboratory studies constitute a basis for this. The high expenses and mathematical work required to carry out proper interlaboratory studies are frequently considered reasons not to conduct such studies. This makes it all the more important to emphasize the various advantages of an accurate interlaboratory study. In addition to providing precision data for the test method, it is also possible to carry out laboratory evaluations, which is important for accredited test laboratories. Furthermore, existing test methods can be optimized, refer- ence material can be obtained, and test methods can be compared. Optimized test instructions can also be generated using the findings and precision data. These advantages will be described in detail by means of examples below.

Analysis on the development of chemically-improved soil in railway engineering

Purpose-Explore the development trend of chemically-improved soil in railway engineering.Design/methodology/approach–In this paper,the technical standards home and abroad were analyzed.Laboratory test,field test and monitoring were carried out.Findings–The performance design system of the chemically-improved soil should be established.Originality/value–On the basis of the performance design,the test methods and standards for various properties of chemically-improved soil should be established to evaluate the improvement effect and control the engineering quality.

航空发动机旋转盘腔内部流动换热特性研究进展综述

The rotating disk cavity is an important part of the cooling-air system of the aero engine,and it has obviously significance to study the internal flow and heat transfer characteristics of the disc cavity,which will be helpful to improve the efficiency of the aero engine.This paper summarizes the existing research results of domestic and overseas.The present work considers the test methods and calculation methods of the flow and heat transfer characteristics of the rotating disc cavity of the aircraft engine.It points out that,the main factors which affect the heat transfer characteristics are the disc chamber speed,the intake volume,the design of the disc cavity pre-rotation/despin structure,and the type of disc cavity system.The influence of these factors on the characteristics of flow heat transfer is summarized.Based on these factors,the disc cavity structure can be optimized and designed,which provides suggestions for reducing the weight of the turbine,improving the thrust-to-weight ratio of the aero engine,and improving the cooling efficiency.

Stress-deformed state of cylindrical specimens during indirect tensile strength testing

In this study, the interaction between cylindrical specimen made ofhomogeneous, isotropic, and linearlyelastic material and loading jaws of any curvature is considered in the Brazilian test. It is assumed thatthe specimen is diametrically compressed by elliptic normal contact stresses. The frictional contactstresses between the specimen and platens are neglected. The analytical solution starts from the contactproblem of the loading jaws of any curvature and cylindrical specimen. The contact width, correspondingloading angle （2 ^0）, and elliptical stresses obtained through solution of the contact problems are used asboundary conditions for a cylindrical specimen. The problem of the theory of elasticity for a cylinder issolved using Muskhelishvili＇s method. In this method, the displacements and stresses are represented interms of two analytical functions of a complex variable. In the main approaches, the nonlinear interactionbetween the loading bearing blocks and the specimen as well as the curvature of their surfacesand the elastic parameters of their materials are taken into account. Numerical examples are solved usingMATLAB to demonstrate the influence of deformability, curvature of the specimen and platens on thedistribution of the normal contact stresses as well as on the tensile and compressive stresses actingacross the loaded diameter. Derived equations also allow calculating the modulus of elasticity, totaldeformation modulus and creep parameters of the specimen material based on the experimental data ofradial contraction of the specimen.

Load Reduction Test Method of Similarity Theory and BP Neural Networks of Large Cranes

Static load tests are an important means of supervising and detecting a crane＇s lift capacity. Due to space restrictions, however, there are difficulties and potential danger when testing large bridge cranes. To solve the loading problems of large-tonnage cranes during testing, an equivalency test is proposed based on the similarity theory and BP neural networks. The maximum stress and displacement of a large bridge crane is tested in small loads, combined with the training neural network of a similar structure crane through stress and displacement data which is collected by a physics simulation progressively loaded to a static load test load within the material scope of work. The maximum stress and displacement of a crane under a static load test load can be predicted through the relationship of stress, displacement, and load. By measuring the stress and displacement of small tonnage weights, the stress and displacement of large loads can be predicted, such as the maximum load capacity, which is 1.25 times the rated capacity. Experimental study shows that the load reduction test method can reflect the lift capacity of large bridge cranes. The load shedding predictive analysis for Sanxia 1200 t bridge crane test data indicates that when the load is 1.25 times the rated lifting capacity, the predicted displacement and actual displacement error is zero. The method solves the problem that lifting capacities are difficult to obtain and testing accidents are easily possible when 1.25 times related weight loads are tested for large tonnage cranes.

Running‑In Behavior of Wet Multi‑plate Clutches:Introduction of a New Test Method for Investigation and Characterization

Wet multi-plate clutches are relevant components of modern drivetrain applications,not only in terms of function but also safety and comfort.Especially at the beginning of their lifetime,distinct changes of the friction behavior may occur and make the actuation of the clutch challenging.This transcript describes the typical running-in behavior of wet multi-plate clutches and gives a general definition for running-in of clutches.Moreover,a new test method to systematically investigate the running-in behavior of clutches is introduced.This test method contains a test procedure to characterize the running-in behavior on different load levels.Furthermore,a multi-stage procedure to evaluate and characterize the running-in behavior of clutches with mathematical approaches and new characteristic values is given.The quality of the test method is demonstrated on the example of three different tribological systems from dual clutch transmissions(DCT)and automatic transmissions(AT)application using paper friction linings.