Background: Scrotal trauma is a rare injury, and can compromise reproductive function. If in closed trauma, a morphological assessment of the lesion is usually necessary before treatment, in open trauma otherwise, nam...Background: Scrotal trauma is a rare injury, and can compromise reproductive function. If in closed trauma, a morphological assessment of the lesion is usually necessary before treatment, in open trauma otherwise, namely in the case of testicular evisceration, surgical exploration is the rule. Objective: To present the management of open scrotal trauma. Case Presentation: These were two adults aged 42 and 63, admitted for post-traumatic testicular evisceration. One of the patients presented with signs of infection due to a diagnosis delay. Management consisted on surgical exploration, with scrotal debridement and testicular reintegration. The evolution was favourable. Conclusion: Open scrotal trauma is a rare lesion that can cause testicular evisceration. It requires surgical exploration, which should be systematic.展开更多
Gunshot wound is rare on the testicles and involves the patient’s reproductive function. The authors report a case of open gunshot wound trauma to the testicles in a 45-year-old patient with no particular information...Gunshot wound is rare on the testicles and involves the patient’s reproductive function. The authors report a case of open gunshot wound trauma to the testicles in a 45-year-old patient with no particular information, except, living with two women and eight children. Emergency sharing noted a fracture of the right testicle with damage of the cord components. After the surgery, the left testicle was necrotic, so a left orchiectomy was performed. The aftermaths of this second surgery were simple. However, the management of this hunting accident resulted in castration, which poses the problem of the patient’s sexuality.展开更多
目的:研究大鼠单侧睾丸损伤后对侧睾丸组织变化及其发生机制。方法:选择SD雄性大鼠40只,随机分为4组:A组为对照组,B组为单侧睾丸挫伤组,C组为单侧睾丸裂伤组,D组为裂伤后腹腔注射环孢素A(cyclosporin A,CsA)组。分别于第2、4周观察大鼠...目的:研究大鼠单侧睾丸损伤后对侧睾丸组织变化及其发生机制。方法:选择SD雄性大鼠40只,随机分为4组:A组为对照组,B组为单侧睾丸挫伤组,C组为单侧睾丸裂伤组,D组为裂伤后腹腔注射环孢素A(cyclosporin A,CsA)组。分别于第2、4周观察大鼠后足垫反应(foot pad reaction,FPR),取对侧睾丸做苏木精-伊红(HE)染色和免疫组化检测CD_4分子、CD_8分子的表达。结果:注射睾丸抗原48 h后,B、C组大鼠右足足垫较A、D组显著增厚(P<0.01),C组与B组差异亦有显著统计学意义(P<0.05),A组与D组差异无统计学意义(P>0.05)。B、C组对侧睾丸组织学发生明显改变,A、D组改变不明显。B、C组中CD_4^+T细胞平均光密度(OD)值高于CD_8^+T细胞(P<0.05),两种T细胞OD值均明显高于对照组(P<0.01),C组与B组比较,CD_4^+T细胞OD值差异有统计学意义(P<0.05),CD_8^+T细胞OD值差异无统计学意义(P>0.05)。各组结果在第2、4周比较,差异均无统计学意义。结论:单侧睾丸损伤可引起对侧睾丸组织发生迟发型超敏反应(delayed type hypersensitivity,DTH),主要由CD_4^+T细胞介导,且与睾丸损伤程度有关。CsA可抑制DTH的发生。展开更多
文摘Background: Scrotal trauma is a rare injury, and can compromise reproductive function. If in closed trauma, a morphological assessment of the lesion is usually necessary before treatment, in open trauma otherwise, namely in the case of testicular evisceration, surgical exploration is the rule. Objective: To present the management of open scrotal trauma. Case Presentation: These were two adults aged 42 and 63, admitted for post-traumatic testicular evisceration. One of the patients presented with signs of infection due to a diagnosis delay. Management consisted on surgical exploration, with scrotal debridement and testicular reintegration. The evolution was favourable. Conclusion: Open scrotal trauma is a rare lesion that can cause testicular evisceration. It requires surgical exploration, which should be systematic.
文摘Gunshot wound is rare on the testicles and involves the patient’s reproductive function. The authors report a case of open gunshot wound trauma to the testicles in a 45-year-old patient with no particular information, except, living with two women and eight children. Emergency sharing noted a fracture of the right testicle with damage of the cord components. After the surgery, the left testicle was necrotic, so a left orchiectomy was performed. The aftermaths of this second surgery were simple. However, the management of this hunting accident resulted in castration, which poses the problem of the patient’s sexuality.
文摘目的:研究大鼠单侧睾丸损伤后对侧睾丸组织变化及其发生机制。方法:选择SD雄性大鼠40只,随机分为4组:A组为对照组,B组为单侧睾丸挫伤组,C组为单侧睾丸裂伤组,D组为裂伤后腹腔注射环孢素A(cyclosporin A,CsA)组。分别于第2、4周观察大鼠后足垫反应(foot pad reaction,FPR),取对侧睾丸做苏木精-伊红(HE)染色和免疫组化检测CD_4分子、CD_8分子的表达。结果:注射睾丸抗原48 h后,B、C组大鼠右足足垫较A、D组显著增厚(P<0.01),C组与B组差异亦有显著统计学意义(P<0.05),A组与D组差异无统计学意义(P>0.05)。B、C组对侧睾丸组织学发生明显改变,A、D组改变不明显。B、C组中CD_4^+T细胞平均光密度(OD)值高于CD_8^+T细胞(P<0.05),两种T细胞OD值均明显高于对照组(P<0.01),C组与B组比较,CD_4^+T细胞OD值差异有统计学意义(P<0.05),CD_8^+T细胞OD值差异无统计学意义(P>0.05)。各组结果在第2、4周比较,差异均无统计学意义。结论:单侧睾丸损伤可引起对侧睾丸组织发生迟发型超敏反应(delayed type hypersensitivity,DTH),主要由CD_4^+T细胞介导,且与睾丸损伤程度有关。CsA可抑制DTH的发生。
