Novel chiral tetraaza ligands（R）-N,N′-bis[2-（piperidin-1-yl）benzylidene]propane-l,2-diamine 6 and（S）-N-[2-（piperidin-l- yl）benzylidene]-3-{[2-（piperidin-1-yl）benzylidene]amino}-alanine sodium salt 7 have be...Novel chiral tetraaza ligands（R）-N,N′-bis[2-（piperidin-1-yl）benzylidene]propane-l,2-diamine 6 and（S）-N-[2-（piperidin-l- yl）benzylidene]-3-{[2-（piperidin-1-yl）benzylidene]amino}-alanine sodium salt 7 have been synthesized and fully characterized by NMR,IR,MS and CD spectra.The catalytic property of the ligands was investigated in Ir-catalyzed enantioselective transfer hydrogenation of ketones.The corresponding optical active alcohols were obtained with high yields and moderate ees under mild reaction conditions.展开更多
合成了两个手性四氮配体,(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]乙二胺(A)和(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]丙二胺(B),及其手性镍(Ⅱ)配合物1和2,采用元素分析、1 H NMR、MS和IR对它们进行了...合成了两个手性四氮配体,(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]乙二胺(A)和(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]丙二胺(B),及其手性镍(Ⅱ)配合物1和2,采用元素分析、1 H NMR、MS和IR对它们进行了表征.研究了手性配合物催化苯乙酮的不对称氢转移反应,考察了碱量和反应时间对催化活性的影响.展开更多
基金the National Natural Science Foundation of China(Nos.20423002,20923004,and 21173176)Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1036)State Key Laboratory of Physical Chemistry of Solid Surfaces for financial support
文摘Novel chiral tetraaza ligands（R）-N,N′-bis[2-（piperidin-1-yl）benzylidene]propane-l,2-diamine 6 and（S）-N-[2-（piperidin-l- yl）benzylidene]-3-{[2-（piperidin-1-yl）benzylidene]amino}-alanine sodium salt 7 have been synthesized and fully characterized by NMR,IR,MS and CD spectra.The catalytic property of the ligands was investigated in Ir-catalyzed enantioselective transfer hydrogenation of ketones.The corresponding optical active alcohols were obtained with high yields and moderate ees under mild reaction conditions.
文摘合成了两个手性四氮配体,(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]乙二胺(A)和(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]丙二胺(B),及其手性镍(Ⅱ)配合物1和2,采用元素分析、1 H NMR、MS和IR对它们进行了表征.研究了手性配合物催化苯乙酮的不对称氢转移反应,考察了碱量和反应时间对催化活性的影响.
