Analysis of the Current Situation of Drug Clinical Trial Institutions in Shaanxi Province

To understand the current situation of institutional registration in Shaanxi Province after the implementation ofregistration system management in drug clinical trial institutions.Relevant information was collected on the“Announcement on the Accreditation of Drug Clinical Trial Institutions”issued by the National Medical Products Administration from 2005 to August 2022,the record management information system of drug and medical device clinical trial institutions,and the drug clinical trial registration and information publicity platform.A retrospective analysis was carried out in terms of institutional development,regional distribution,registered majors,principal investigators,and the number of drug clinical trials.After the implementation of institution registration,the number of drug clinical trial institutions in Shaanxi Province increased by 47.4%,884 principal investigators were registered,the number of registered majors expanded from 58 qualified to 117,and the professional scope increased by 50.4%.The policy of institution registration is conducive to promoting the rational use of medical resources and the development of drug clinical trial institutions and improving the healthy development of the pharmaceutical industry in Shaanxi Province.

Quantitative analysis of the dynamic change and spatial differences of the ecological security: a case study of Loess Plateau in northern Shaanxi Province

Using the theory and method of the ecological footprint, and combining the changes of regional land use, resource environment, population, society and economy, this paper calculated the ecological footprint, ecological carrying capacity and ecological surplus/loss in 1986-2002 on the Loess Plateau in northern Shaanxi Province. What is more, this paper has put forward the concept of ecological pressure index, set up ecological pressure index models, and ecological security grading systems, and the prediction models of different ecological footprints, ecological carrying capacity, ecological surplus and ecological safety change, and also has assessed the ecological footprint demands of 10,000 yuan GDE The results of this study are as follows： （1） the ecological carrying capacity in northern Shaanxi shows a decreasing trend, the difference of reducing range is the fastest; （2） the ecological footprint appears an increasing trend; （3） ecological pressure index rose to 0.91 from 0.44 during 1986-2002 on the Loess Plateau of northern Shaanxi with an increase of 47%; and （4） the ecological security in the study area is in a critical state, and the ecological oressure index has been increasing rapidlv.

A New Ootype of Dinosaur Egg (Faveoloolithidae： Duovallumoolithus shangdanensis oogen, et oosp. nov.) from the Late Cretaceous in the Shangdan Basin, Shaanxi Province, China

A new ootype collected from the Upper Cretaceous Lijiacun Formation in the Shangdan Basin,Shaanxi Province is described in this paper. Based on general external shape, size, eggshell thickness and honeycomb-like eggshell microstructure, eggs are referable to the oofamily Faveoloolithidae. Compared with other members of Faveoloolithidae, specimens described in this paper show special characteristics:adjacent pores are usually separated by two eggshell units between which often develop interspaces;columnar eggshell units are relatively closely arranged in radial view. According to these characteristics,we erect a new oogenus and a new oospecies: Duovallumoolithus shangdanensis oogen. et oosp. nov. The new discovery expands the diversity of Faveoloolithidae.

On the Genesis of the Super-large Baguamiao Gold Deposit in Fengxian County, Shaanxi Province

The Baguamiao gold deposit in Fengxian County, Shaanxi Province, is a recentlyexplored super-large gold ore deposit. A comprehensive and deep-going study has revealedthat it is a polygenetic deposit: early-stage mineralization due to shearing, middle-stagemineralization due to hydrothermal alteration, and late-stage mineralization due toweathering, leaching and concentration at shallow depths. Shearing played a dominant role inthe formation of gold orebodies.

Change Characteristics and Cause Analysis of Summer Precipitation Anomaly in Loess Plateau of Northern Shaanxi Province

[ Objective] The research aimed to study change characteristics and formation cause of summer precipitation abnormality in Loess Plateau of northern Shaanxi Province. [ Method] Based on summer precipitation data at 15 observation stations in Loess Plateau of northern Shaanxi Province and NCEP/NCAR dataset from 1961 to 2008, change characteristics of summer precipitation in the region were investigated by using linear trend estimation and composite analysis. [Result] Summer rainfall had decrease trend in most parts of northem Shaanxi Province, but had increase trend in western and southern regions. The interannual and interdecadal variations were obvious. It had a large amount of precipitation from the mid- 1970s to the mid-1990s, while summer rainfall had decrease trend after the mid-1990s and increase trend in recent years. In wet years, it was a large positive anomaly zone from western Ural Mountains to northem Lake Baikal at middle and high latitudes, indicating that there was a blocking high over the Ural Mountains, while it was negative anomaly zone from northern Okhotsk Sea to Lake Baikal. From Northwest Pacific Ocean to Bo- hal Sea Bay and North China, it was a wide range of significant positive anomaly zone, which was favorable for Westem Pacific subtropical high ex- tending westward and northward. The analysis in dry years showed opposite circulation configuration. It was ＂ -, ＋, -＂ wave train distribution in middle and high latitudes and positive anomaly zone along the Sea of Okhotsk. Western Pacific subtropical high was also by south and east. Major water vapor was from southeast direction in wet years, and abundant water vapor caused more summer rainfall in northern Shaanxi. In dry years, water vapor was from westerly tuming southerly flow. It was weaker and by east. [ Conclusion] The research provided reference for reasonable utilization of summer precipitation in the zone.

Analysis on Characteristics and Functions of the Peasant Workers' Returning Home for Venturing in Shaanxi Province

Features and effects of returned migrant workers' entrepreneurship in Shaanxi Province are analyzed.Returned migrant workers' entrepreneurship in Shaanxi Province depends on traditional agriculture to develop the quantitative business of planting and breeding,local resources to develop the processing of building materials and agricultural products,small towns to develop service industry such as catering and tourism and the capital accumulated when working in the outside to achieve the transformation from an ordinary worker to an entrepreneur.Returned migrant workers' entrepreneurship in Shaanxi Province promotes the employment and expends ways of transferring rural labor force and increasing incomes.Advantageous recourses are attracted to the rural and underdeveloped areas,which is beneficial to narrowing the gap between the urban and rural areas.It can also promote the transformation of agricultural developmental methods and speed the pace of building modern agriculture.And a group of talents with higher qualities are provided for new rural construction through the modeling and leading role.Entrepreneurship and urbanization are combined together to advance the process of rural urbanization.

The Taxonomic Status of Spermophilus in the Plague Area of Dingbian County,Shaanxi Province,China

This study was conducted to define the taxonomic status of Spermophilus in the plague area of Dingbian County in Shaanxi Province,China,through the two-factor variance analysis of morphological characteristics,DNA barcoding,and chromosome karyotype analysis.

Current situation and human health risk assessment of fluoride enrichment in groundwater in the Loess Plateau:A case study of Dali County,Shaanxi Province,China

This study aims to investigate the mechanisms and health risks of fluoride enrichment in groundwater in the Loess Plateau,China.By taking Dali County,Shaanxi Province,China as an example,this study obtains the following results through field investigation and the analyses of water,soil,and crop samples.(1)The groundwater can be divided into two major types,namely the Quaternary pore-fissure water and Karst water.The Karst area and sandy area have high-quality groundwater and serve as the target areas for optional water supply.The groundwater in the study area is slightly alkaline and highly saline.Meanwhile,high-fluoride groundwater is mainly distributed in the loess and river alluvial plains in the depression area of the Guanzhong Basin and the discharge areas of the groundwater,with the highest fluoride concentration exceeding seven times the national standard.(2)Fluoride in groundwater mainly originates from a natural source and human activities.The natural source refers to the fluoride-bearing minerals in rocks and soil,and the fluoride from this source is mainly controlled by natural factors such as climate,geologic setting,pH,specific hydrochemical environment,ion exchange,and mineral saturation.Human activities in modern life can be further divided into industrial and agricultural sources primarily.(3)The health risks of fluoride contamination are very high in the Loess Plateau,especially for children compared to adults.Meanwhile,the risks of fluoride exposure through food intake are higher than those through drinking water intake.The authors suggest selecting target areas to improve water supply and ensure the safety of drinking water in the study area.Besides,it is necessary to plant crops with low fluoride content or cash crops and to conduct groundwater treatment to reduce the fluoride concentration in drinking water.These results will provide a theoretical basis for safe water supply in the faulted basin areas in the Loess Plateau.

Formation of the Micro-Disseminated Strata-bound Gold Deposits, With Special Reference to Structural Evolution, Miliang Area, Zhen'an County,Shaanxi Province, China

Based on detailed geologic study, the important role of structuring in the formation of gold deposits in the area is discussed with special reference to structural evolution. Syngenetic faulting contemporaneous with tectonic-volcanic events is thought to be responsible for providing the ore-forming material at depth. The lithofacies formed by highly alternating deposition of terrestrial and carbonate detritus is chemically characterized by the assemblage of Au-Sb-As,constituting a favorable source bed for the activation and enrichment of gold. This gold source bed has undergone four major stages of structural deformation, accompanied by multi-staged alteration and mineralization.

Empirical Analysis on the Determinants of Economic Growth in Shaanxi Province, China

Status of economic development in Shaanxi Province is analyzed, showing that Shaanxi Province has achieved the fast and stable economic growth; and total GDP and fixed assets investment have shown a sustainable growth. According to the time series statistics of Shaanxi Province in the years 1978-2008, Cobb-Douglas Function is used to carry out the empirical analysis on the contribution of fixed assets investment and labor input to economic growth of Shaanxi Province, China. Result shows that capital and labor input are the major driving forces for the economic growth of Shaanxi Province. In other words, economic growth mode of Shaanxi Province is still extensive. Economic growth of Shaanxi Province is increasingly dependent on capital investment and technological progress. Contribution rates of capital and labor to economic growth are 66.9% and 33.1%, respectively. Therefore, investment is a source of economic growth in Shaanxi Province through the reform and opening up in the last three decades.

Preliminary prediction of the control reproduction number of COVID-19 in Shaanxi Province,China

Objectives Firstly,according to the characteristics of COVID-19 epidemic and the control measures of the government of Shaanxi Province,a general population epidemic model is es-tablished.Then,the control reproduction number of general population epidemic model is obtained.Based on the epidemic model of general population,the epidemic model of general population and college population is further established,and the control reproduction number is also obtained.Methods For the established epidemic model,firstly,the expression of the control reproduc-tion number is obtained by using the next generation matrix.Secondly,the real-time reported data of COVID-19 in Shaanxi Province is used to fit the epidemic model,and the parameters in the model are estimated by least square method and MCMC.Thirdly,the Latin hypercube sampling method and partial rank correlation coefficient(PRCC)are adopted to analyze the sensitivity of the model.Conclusions The control reproduction number remained at 3 from January 23 to January 31,then gradually decreased from 3 to slightly greater than 0.2 by using the real-time reports on the number of COVID-19 infected cases from Health Committee of Shaanxi Province in China.In order to further control the spread of the epidemic,the following measures can be taken:(i)reducing infection by wearing masks,paying attention to personal hygiene and limiting travel;(i)improving isolation of suspected patients and treatment of symptomatic individuals.In particular,the epidemic model of the collge population and the general population is estab-lished,and the control reproduction number is given,which will provide theoretical basis for the prevention and control of the epidemic in the colleges.

Geological Features and Genesis of the Jinduicheng Porphyry Molybdenum Deposit, Shaanxi Province, China

Situated in the Henan-Shaanxi fault-uplift area on the southern margin of the Sino-Korean Paraplatform,the jinduicheng porphyry molybdenum deposit is the most important molybdenum producer in China.During Yenshanian the Jinduicheng granite porphyry was emplaced in metaspilite of the Proterozoic XiongerGroup,controlled by a NW trending fault Mineral compositions are mainly quartz （25-40％）,microclineand microcline perthite（27-40％）and plagioclase（An8-14-,14-32％）,associated with minor biotite andmuscovite,and phenocrysts are made up of K-feldspar,quartz and phagioclase.Accessory minerals includemagmatite,apatite and zircon,The porphyry contains SiO2 73.83％ and K2O+Na2O 8.06％（withK2O/Na2O ratio being 1.82）,beloning to the calc-alkaline series Mineralization occurs in the porphyry body and biotitized and hornfelsized spilite Within the exocontactzone.The maximum depth of mineralization reaches 1000 meters below the surface.According to mineralassemblage,ore veins are classified into five types:（l） Pyrite-quartz;（2） Pyrite-K-feldspar-quartz; （3）pyrite-molybdenite-quartz:（4） pyrite-molybdenite-K-feldspar-quartz;and（5） Muscovitefluorite-pyrite-molybdenite-quartz. As the most important economic molybdenum mineral,molybdenite occurs in various forms.Wall-rockalterations show a gross zonation of K-feldspathization-greisenization→silicification→propylitization fromthe porphyry outwards,of which silicification is most intense and has close genetic relationship with Momineralization. Fluid inclusion studies yield homogeneous temperatures ranging from 240to240℃,with the main stagebetween 400 and 300℃.Gas inclusions frequently coexist with multiphase inclusions containing suchdaughter minerals as halite,sylvite,molybdenite and K-feldspar.Under moderate-high temperatures,lowerfo2,high fs2 and weak。acidity conditions,boiling of ore-forming fluids is prerequisite for the Precipitation ofmolybdenite. Sulfur,oxygen and carbon isotopic compositions suggest that at the high temperature stage（450℃）magmatic water is dominant and at the main ore-forming stage a mixture of mixture of magmatic water and meteoricwater is expected.At the late stage,the mixture is predominated by meteoric water.Sulfur and molybdenumare mostly of magmatic origin.

Analysis on the Changing Trends of Surface Water Quality and Their Causes of Weihe River in Shaanxi Province during Recent Ten Years

[ Objective] The study aimed to analyze the changing trends of surface water quality and their causes of Weihe River in Shaanxi Province over past ten years. [ Method] Based on the available monitoring data of water quality of Weihe River in Shaanxi Province from 2001 to 2010, the changing trends of surface water quality of Weihe River in Shaanxi Province during recent ten years were assessed by using the assessment method of surface water quality according to the Assessment Method of Surface Water Quality and Environmental Quality Standards for Surface Water （GB 3838-2002）. Moreover, the possible reasons for the trends were also proposed. [ Result] From 2001 to 2010, there was a relatively decrea- sing trend of water pollution in Weihe River due to the considerable decline in the content of the main environmental pollutants like permanganate in- dex, 5-day biochemical oxygen demand （ BOD5 ）, ammonia nitrogen, oil and volatile phenol. Meanwhile, the comprehensive pollution index fell by 62.7%, eliminating Weihe River＇s black and stink on schedule. However, the overall surface water quality of Weihe River was still polluted heavily in each year, and the pollution control of Xi＇an section should be paid more attention to. [ Conclusion] The research could provide scientific refer- ences for the comprehensive environmental control of Weihe River in Shaanxi Province.

Adjusting the information service strategies according to users' requirements—A survey of the library users' information requirements in the four library systems of Zhejiang province

Based on a survey of the circumstances of the information requirements in social science from more than 3,800 library users in 48 libraries of the four major library systems in Zhejiang Province,this paper analyzes the present main characteristics of the users' requirements to the social science document information and puts forward some proposals for adjusting the document information service strategies for the library and information institutions.

A Study on the Needs and the Way of the International Talents Training for Shaanxi Under"the Belt and Road"

This article,emphatically analyzes the needs and the way of internationall talents training for Shaanxi under"the Belt and Road".And it’s hoped that the results can be helpful for providing Shaanxi with solid talents support under the opportunity of"the Belt and Road".

Changes in Ecosystem Service Values on the Loess Plateau in Northern Shaanxi Province,China

The Loess Plateau in northern Shaanxi Province of China covers Yulin, Yan＇an, and Tongchuan cities mainly. The kind of physiognomy is complicated and various, including the transitional region of the sand and wind, the hilly-gully fragile region, the pimple mound region from North to South. Large-scale land reclamation projects that are severely affecting these ecosystems have been implemented. In this paper, we reported an investigation to the changes in land use and ecosystem services on the Loess Plateau in northern Shaanxi Province from 1978 to 2000. We used three LANDSAT TM and/or ETM data sets to estimate the changes in the size of five land-cover/land-use categories, and we also used previously published value coefficients to estimate the changes in the value of ecosystem services delivered by each land category. Finally, we ranked the contribution of various ecosystem functions to the overall value of the ecosystem services, we have estimated that the annual value of the ecosystem services is 56.95 billon RMB yuan in the Loess Plateau in northern Shaanxi Province in 2000. In the region, from 1978 to 2000, the economic value of the fixing carbon was higher, the economic value of water conservation was the lowest, but the economic value of the NPP, fixing carbon, and supplying oxygen accounted for above ninety percent of the total value, obviously the vegetation created the biggest ecosystem service value. We can conclude that future land-use policy formulation should give precedence to the conservation of these ecosystems over uncontrolled reclamation, and that further land reclamation should be based on rigorous environmental impact analyses.

The Income Gap among Rural Residents in Shaanxi Province,China

According to the analysis on the current status of the income gap among rural residents in Shaanxi Province,it is found out that the income of rural residents in Shaanxi Province of China is not only lower than the average income level of China,but also far lower than the income level of urban residents and the income level of rural residents in developed areas.The low income is mainly caused by the increasing income gap among income groups and the income gap among rural residents in different areas.Based on this,causations for the income gap among rural residents are analyzed from three aspects of the cultural difference,the regional economic difference,and the industrial structure difference.Countermeasures for narrowing the income gap and increasing the farmers' income in Shaanxi Province are put forward,such as vigorously developing the rural economy and speeding up the transfer of rural surplus labor forces in China.

Thinking on Effective Methods of Successful Prediction of Geological Hazards in Shaanxi, China

In the process of human survival and development, it is inevitable to transform the original state of the world, thus forming a contradiction between the earth and the earth. The violent form of this contradiction is geological disasters. Geological disasters pose a threat to human life and property, and cause damage caused by natural or human factors, often causing casualties. The destruction process of geological disasters is usually a gradual process, showing many pre-disaster symptoms, such as local landslides, surface cracks, building deformation, tree skew, and ground sound. Evacuation can be avoided in advance according to the disaster precursors, so as to avoid casualties and achieve successful prediction. By reviewing the general situation of geological disasters in Shaanxi Province and the casualties in 2020, the difficulties in the prevention and control of geological disasters are summarized. In view of these difficulties, an on-site investigation, visit and analysis of geological disaster points and successful forecast points in Shaanxi Province in 2020 were conducted. In addition, combined with actual cases and years of work experience, the successful prediction experience of geological disasters was discussed from 8 aspects. Finally, the “Regulations on the Reward for Successful Geological Disaster Forecasting in Shaanxi Province” was revised in order to improve the successful prediction ability of geological disasters in Shaanxi Province and even the whole country, provide reference for future prevention and control of geological disasters, and effectively protect the safety of people’s lives and property.

Division of diagenesis reservoir facies and its control——Case study of Chang-3 reservoir in Yangchang formation of Fuxian exploration area in northern Shaanxi

By dividing the diagenetic reservoir facies and studying its distribution,we can effectively evaluate reservoirs.Using an analytical method for mutual relationships among diagenesis of reservoirs,structural characteristics and the origin of types of sand,we classified the diagenetic reservoir of the Yanchang formation Chang-3 oil layer into different types and analyzed the factors controlling this high quality reservoir.The results show that:1) the catagenesis of the Chang-3 oil layer in the Fuxian region is complex and variable;2) mechanical compaction,pressure solutions and cementation of all kinds of authogenous minerals decreases porosity by 28.13% and 3) corrosion increases porosity by 3.39%.Cementation and corrosion of laumontite is a kind of catagenesis which makes this region different from other exploratory regions.The original amount and rate of corrosion of laumontite are the main factors for the increase in laumontite porosity.The Chang-3 oil layer developed four kinds of diagenetic reservoir facies,of which the weak compaction facies,i.e.,laumontite corrosion and overgrowth,of the original pore reservoir facies has the most promising diagenesis.Its distribution is controlled by a sedimentary facies zone and is widely developed in the original truncated tributary channel facies belt of the delta plain.The development of this high quality reservoir is controlled by the distribution of sedimentary sand bodies and secondarily-eroded porosity of laumontite in the Chang-3 oil layer of the Fuxian exploratory region.

EMERGY ANALYSIS OF GRAIN PRODUCTION SYSTEM IN JIANGSU AND SHAANXI PROVINCE

Efficiency and sustainability of grain production are now important in China. In this study, the grain production systems of Jiangsu and Shaanxi Provinces were compared, to analyze their efficiency and sustainability in terms of utilization of natural resources, inputs of purchased energy and materials, and outputs. Flows of energy and materials between environment and human society were identified, and the natural and human work involved in generating inputs as materials or energy were valued in terms of equivalent amount of solar energy required for their production using emergy method. The results showed environmental resources were continually playing a less important role in the systems, when inorganic subsidiary emergy inputs increased drastically while organic ones decreased or increased little. Deterioration of input emergy structure affected the systems′ efficiency and sustainability,resulting in emergy investment ratios and environmental loading ratios increasing while yield ratios and sustainability indices decreasing. In general, efficiency and sustainability of grain production in Jiangsu are worse than those in Shaanxi. This analysis also suggested that inorganic subsidiary emergy should be introduced properly, and peasants in Jiangsu should utilize natural conditions wisely while those in Shaanxi pay enough attention to soil and surface water conservation.