BACKGROUND Retinoblastoma(Rb)is primarily found in infants or young children.The most common primary presenting sign of Rb is leukocoria.Rb is very rare in children who are 10 years old or older.Timely and correct dia...BACKGROUND Retinoblastoma(Rb)is primarily found in infants or young children.The most common primary presenting sign of Rb is leukocoria.Rb is very rare in children who are 10 years old or older.Timely and correct diagnosis as well as proper treatment are the key factors affecting the prognosis of Rb.CASE SUMMARY A 10-year-old girl with symptoms of vision loss,redness,swelling and pain in the right eye for 2 mo was admitted to our Department of Ophthalmology.The visual acuity of the right eye was graded as hand movement.The intraocular pressure of the eye was 46.9 mmHg.No substantial space-occupying lesion or characteristic calcified plaque was found in the eye.The patient underwent anterior chamber irrigation under general anesthesia on the same day of admission,and 2 mL of irrigation solution was saved for pathological examination.Histopathological examination of the anterior chamber fluid revealed cancer cells.A diagnosis of Rb with masquerade syndrome was made.The patient underwent enucleation followed by 6 rounds of systematic chemotherapy.A follow-up examination almost 9 years later found no relapse of Rb.CONCLUSION For older pediatric patients who have secondary glaucoma and uveitis symptoms without a clear cause of the disease and have no space-occupying lesion found by imaging examination,aqueous humor or vitreous humor examination is recommended for timely and correct diagnosis and appropriate treatment.展开更多
The objectives of this study were to assess the prevalence of students' fruit and vegetable intake and its associated factors among adolescents in Mongolia. Data for this analysis were from the 2010 Mongolia Global S...The objectives of this study were to assess the prevalence of students' fruit and vegetable intake and its associated factors among adolescents in Mongolia. Data for this analysis were from the 2010 Mongolia Global School-Based Health Survey (GSHS). The GSHS administered a self-report questionnaire to a nationally representative sample (N = 5,328) of 7th-llth grade school children. Chi-square analyses and multivariate logistic regressions were performed to determine the prevalence and to predict the fruit and vegetable intake from associated factors. Only 7.0% of students met WHO's recommendation of eating fruits and vegetables S or more times per day. There was a significant association between gender and fruit and vegetable intake (P = .016). There was a significant relationship between living condition and fruit and vegetable intake (P =.029). Students who lived in apartment were more likely to have adequate fruit and vegetable intake than those who lived in ger in the khashaa. To be effective, educational interventions should be implemented as early as possible.展开更多
AIM: To assess values of 24-h esophageal pH-monitoring parameters with dual-channel probe (distal and proximal channel) in children suspected of gastroesophageal reflux disease (GERD). METHODS: 264 children suspected ...AIM: To assess values of 24-h esophageal pH-monitoring parameters with dual-channel probe (distal and proximal channel) in children suspected of gastroesophageal reflux disease (GERD). METHODS: 264 children suspected of gastroesophageal reflux (GER) were enrolled in a study (mean age χ = 20.78 ± 17.23 mo). The outcomes of this study, immunoallerrgological tests and positive result of oral food challenge test with a potentially noxious nutrient, enabled to qualify children into particular study groups. RESULTS: 32 (12.1%) infants (group 1) had physiological GER diagnosed. Pathological acid GER was confirmed in 138 (52.3%) children. Primary GER was diagnosed in 76 (28.8%) children (group 2) and GER secondary to allergy to cow milk protein and/or other food (CMA/FA) in 62 (23.5%) children (group 3). 32 (12.1%) of them had CMA/FA (group 4-reference group), and in remaining 62 (23.5%) children neither GER nor CMA/FA was confirmed (group 5). Mean values of pH monitoring parameters measured in distal and proximal channel were analyzed in individual groups. This analysis showed statistically significant differentiation of mean values in the case of: number of episodes of acid GER, episodes of acid GER lasting > 5 min, duration of the longest episode of acid GER in both channels, acid GER index total and supine in proximal channel. Statistically significant differences of mean values among examined groups, especially between group 2 and 3 in the case of total acid GER index (only distal channel) were confirmed. CONCLUSION: 24-h esophageal pH monitoring confirmed pathological acid GER in 52.3% of children with typical and atypical symptoms of GERD. The similar pH-monitoring values obtained in group 2 and 3 confirm the necessity of implementation of differential diagnosis for primary vs secondary cause of GER.展开更多
Charles Dickens—the greatest representative of English critical realism writer in the 19th century.The age when he lived and his own experience contributed to his more attention to the low-class people of the society...Charles Dickens—the greatest representative of English critical realism writer in the 19th century.The age when he lived and his own experience contributed to his more attention to the low-class people of the society and children's education.His first work of critical realism Oliver Twist is also not exceptional which shows attention of the children's education,compassion and concerning about children's growth in the novel.The author argues from the view of pedagogy to analyze the causes of the tragic fate of five secondary typical characters(Monks,Dick,Noah,Dodger and Charley)to reveal children's educational view of Charles Dickens—the harmony of family relationships,the humanization of school system and the fraternity of social system in Oliver Twist.At the same time,the author would study that children educational view of Charles Dickens's influence on the children's education in our country,especially for the education of delinquent children in modern society.展开更多
文摘BACKGROUND Retinoblastoma(Rb)is primarily found in infants or young children.The most common primary presenting sign of Rb is leukocoria.Rb is very rare in children who are 10 years old or older.Timely and correct diagnosis as well as proper treatment are the key factors affecting the prognosis of Rb.CASE SUMMARY A 10-year-old girl with symptoms of vision loss,redness,swelling and pain in the right eye for 2 mo was admitted to our Department of Ophthalmology.The visual acuity of the right eye was graded as hand movement.The intraocular pressure of the eye was 46.9 mmHg.No substantial space-occupying lesion or characteristic calcified plaque was found in the eye.The patient underwent anterior chamber irrigation under general anesthesia on the same day of admission,and 2 mL of irrigation solution was saved for pathological examination.Histopathological examination of the anterior chamber fluid revealed cancer cells.A diagnosis of Rb with masquerade syndrome was made.The patient underwent enucleation followed by 6 rounds of systematic chemotherapy.A follow-up examination almost 9 years later found no relapse of Rb.CONCLUSION For older pediatric patients who have secondary glaucoma and uveitis symptoms without a clear cause of the disease and have no space-occupying lesion found by imaging examination,aqueous humor or vitreous humor examination is recommended for timely and correct diagnosis and appropriate treatment.
文摘The objectives of this study were to assess the prevalence of students' fruit and vegetable intake and its associated factors among adolescents in Mongolia. Data for this analysis were from the 2010 Mongolia Global School-Based Health Survey (GSHS). The GSHS administered a self-report questionnaire to a nationally representative sample (N = 5,328) of 7th-llth grade school children. Chi-square analyses and multivariate logistic regressions were performed to determine the prevalence and to predict the fruit and vegetable intake from associated factors. Only 7.0% of students met WHO's recommendation of eating fruits and vegetables S or more times per day. There was a significant association between gender and fruit and vegetable intake (P = .016). There was a significant relationship between living condition and fruit and vegetable intake (P =.029). Students who lived in apartment were more likely to have adequate fruit and vegetable intake than those who lived in ger in the khashaa. To be effective, educational interventions should be implemented as early as possible.
基金Supported by Grant of State Committee for Scientific Research (KBN) No 4P05E 04719
文摘AIM: To assess values of 24-h esophageal pH-monitoring parameters with dual-channel probe (distal and proximal channel) in children suspected of gastroesophageal reflux disease (GERD). METHODS: 264 children suspected of gastroesophageal reflux (GER) were enrolled in a study (mean age χ = 20.78 ± 17.23 mo). The outcomes of this study, immunoallerrgological tests and positive result of oral food challenge test with a potentially noxious nutrient, enabled to qualify children into particular study groups. RESULTS: 32 (12.1%) infants (group 1) had physiological GER diagnosed. Pathological acid GER was confirmed in 138 (52.3%) children. Primary GER was diagnosed in 76 (28.8%) children (group 2) and GER secondary to allergy to cow milk protein and/or other food (CMA/FA) in 62 (23.5%) children (group 3). 32 (12.1%) of them had CMA/FA (group 4-reference group), and in remaining 62 (23.5%) children neither GER nor CMA/FA was confirmed (group 5). Mean values of pH monitoring parameters measured in distal and proximal channel were analyzed in individual groups. This analysis showed statistically significant differentiation of mean values in the case of: number of episodes of acid GER, episodes of acid GER lasting > 5 min, duration of the longest episode of acid GER in both channels, acid GER index total and supine in proximal channel. Statistically significant differences of mean values among examined groups, especially between group 2 and 3 in the case of total acid GER index (only distal channel) were confirmed. CONCLUSION: 24-h esophageal pH monitoring confirmed pathological acid GER in 52.3% of children with typical and atypical symptoms of GERD. The similar pH-monitoring values obtained in group 2 and 3 confirm the necessity of implementation of differential diagnosis for primary vs secondary cause of GER.
文摘Charles Dickens—the greatest representative of English critical realism writer in the 19th century.The age when he lived and his own experience contributed to his more attention to the low-class people of the society and children's education.His first work of critical realism Oliver Twist is also not exceptional which shows attention of the children's education,compassion and concerning about children's growth in the novel.The author argues from the view of pedagogy to analyze the causes of the tragic fate of five secondary typical characters(Monks,Dick,Noah,Dodger and Charley)to reveal children's educational view of Charles Dickens—the harmony of family relationships,the humanization of school system and the fraternity of social system in Oliver Twist.At the same time,the author would study that children educational view of Charles Dickens's influence on the children's education in our country,especially for the education of delinquent children in modern society.