Objective To explore the feasibility of mediating recipient lymphocyte reaction with donor dendritic cells ( Dcs) in renal allograft recipients to guide individualized immunosuppressive therapy. Methods From Jan. 2008...Objective To explore the feasibility of mediating recipient lymphocyte reaction with donor dendritic cells ( Dcs) in renal allograft recipients to guide individualized immunosuppressive therapy. Methods From Jan. 2008 to Jan. 2010,30 recipients received living related kidney transplantation were successively and divided into展开更多
Two amphiphilic macromolecules were synthesized from polyethylene glycol monomethylether（PEG）and borondipyrrolmethene（BODIPY） via one-pot multicomponent Passerini reaction,and they could self-assemble into stable ...Two amphiphilic macromolecules were synthesized from polyethylene glycol monomethylether（PEG）and borondipyrrolmethene（BODIPY） via one-pot multicomponent Passerini reaction,and they could self-assemble into stable nanoparticles（NPs） in aqueous media.The optical properties,including fluorescence resonance energy transfer（FRET） were studied in detail.The obtained NPs possess good cytocompatibility,and could be used for living cell imaging and effective photodynamic therapy（PDT）.These results shed light on one-pot synthesis of PEGylated fluorescent nanoparticles via multicomponent reaction for biomedical application.展开更多
文摘Objective To explore the feasibility of mediating recipient lymphocyte reaction with donor dendritic cells ( Dcs) in renal allograft recipients to guide individualized immunosuppressive therapy. Methods From Jan. 2008 to Jan. 2010,30 recipients received living related kidney transplantation were successively and divided into
基金supported by the National Natural Science Foundation of China(Nos.51522307 and 81673396)
文摘Two amphiphilic macromolecules were synthesized from polyethylene glycol monomethylether（PEG）and borondipyrrolmethene（BODIPY） via one-pot multicomponent Passerini reaction,and they could self-assemble into stable nanoparticles（NPs） in aqueous media.The optical properties,including fluorescence resonance energy transfer（FRET） were studied in detail.The obtained NPs possess good cytocompatibility,and could be used for living cell imaging and effective photodynamic therapy（PDT）.These results shed light on one-pot synthesis of PEGylated fluorescent nanoparticles via multicomponent reaction for biomedical application.
