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DEVELOPMENT OF A HYBRID MODEL FOR THREE-DIMENSIONAL GIS 被引量:14
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作者 SHI Wenzhong 《Geo-Spatial Information Science》 2000年第2期6-12,共7页
This paper presents a hybrid model for three_dimensional Geographical Information Systems which is an integration of surface_ and volume_based models.The Triangulated Irregular Network (TIN) and octree models are inte... This paper presents a hybrid model for three_dimensional Geographical Information Systems which is an integration of surface_ and volume_based models.The Triangulated Irregular Network (TIN) and octree models are integrated in this hybrid model.The TIN model works as a surface_based model which mainly serves for surface presentation and visualization.On the other hand,the octree encoding supports volumetric analysis.The designed data structure brings a major advantage in the three_dimensional selective retrieval.This technique increases the efficiency of three_dimensional data operation. 展开更多
关键词 混合三维的模型 听模型 octree 模型 GIS
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A three-dimensional semi-implicit unstructured grid finite volume ocean model 被引量:10
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作者 WANG Zhili GENG Yanfen 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2013年第1期68-78,共11页
A new three-dimensional semi-implicit finite-volume ocean model has been developed for simulating the coastal ocean circulation, which is based on the staggered C-unstructured non-orthogonal grid in the hor- izontal d... A new three-dimensional semi-implicit finite-volume ocean model has been developed for simulating the coastal ocean circulation, which is based on the staggered C-unstructured non-orthogonal grid in the hor- izontal direction and z-level grid in the vertical direction. The three-dimensional model is discretized by the semi-implicit finite-volume method, in that the free-surface and the vertical diffusion are semi-implicit, thereby removing stability limitations associated with the surface gravity wave and vertical diffusion terms. The remaining terms in the momentum equations are discretized explicitly by an integral method. The partial cell method is used for resolving topography, which enables the model to better represent irregular topography. The model has been tested against analytical cases for wind and tidal oscillation circulation, and is applied to simulating the tidal flow in the Bohal Sea. The results are in good agreement both with the analytical solutions and measurement results. 展开更多
关键词 three-dimensional model finite volume unstructured grid SEMI-IMPLICIT z-level grid
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The study on three-dimensional numerical model and fronts of the Jiulong Estuary and the Xiamen Bay 被引量:3
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作者 LUO Zhibin PAN Weiran +1 位作者 LI Li ZHANG Guorong 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2012年第4期55-64,共10页
Applying the methods of on-site observation and dynamic model, the research on the fronts at the Jiulong Estuary has been carried out, during which spatial and temporal distribution, dynamic characteristics and format... Applying the methods of on-site observation and dynamic model, the research on the fronts at the Jiulong Estuary has been carried out, during which spatial and temporal distribution, dynamic characteristics and formation mechanism of salinity fronts are analyzed and discussed. The research shows that the estuarine fronts mainly lie in the area from the Jiyu Islet to the Haimen Island, outside of Yuweizai to Hulishan cross-section, the near coast of Yuweizai and the south of the Songyu-Gulangyu Channel. The fronts in the former two regions are formed directly by plume, while the one near the coast of Yuweizai is a tidal intrusion front caused by flood current and the one at the south of the Songyu-Gulangyu Channel is the result of current shear transformation. Under normal circumstances, fresh water of the Jiulong River mainly influences the inside of the Xiamen Bay, and when it is in typhoon seasons, plume front can affect the Taiwan Strait and has an effect on the biogeochemical Drocesses in the strait. 展开更多
关键词 Jiulong Estuary Xiamen Bay three-dimensional numerical model FRONTS
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Risk Assessment of Coal Mine Water Hazard Based on Three-Dimensional Model of Geology and Underground Space 被引量:1
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作者 Kai Zhang~1,Ming Huang~1,Bin Tang~2,Fan Cui~1 1.Laboratory of Coal Resources and Mine Safety,China University of Mining and Technology,Beijing 100083,China. 2.China Water Investment Co.Ltd,Beijing 100053,China 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期279-279,共1页
Mine safety have top-five disasters,which including the water,gas,fire,dust and geological dynamic disaster.The coal mine water disaster is one of the important factors which restricted the development of China’s coa... Mine safety have top-five disasters,which including the water,gas,fire,dust and geological dynamic disaster.The coal mine water disaster is one of the important factors which restricted the development of China’s coal production.It is showed by statistics that 60%of mine accidents are affected by groundwater,which not only result in the production losses,casualties and a variety of 展开更多
关键词 DISASTER risk assessment three-dimensionAL model of GEOLOGY and UNDERGROUND space emergency RESCUE
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A NEW UNSTEADY THREE DIMENSIONAL MODEL FOR MACROMOLECULAR TRANSPORT AND WATER FILTRATION ACROSS THE ARTERIAL WALL 被引量:1
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作者 HUANG Hao(黄浩) +1 位作者 WEN Gong-bi(温功碧) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2001年第10期1155-1172,共18页
A new unsteady three-dimensional convective-diffusive mathematical model for the transportation of macromolecules and water across the arterial wall was proposed . After the formation of leaky junctions due to the mit... A new unsteady three-dimensional convective-diffusive mathematical model for the transportation of macromolecules and water across the arterial wall was proposed . After the formation of leaky junctions due to the mitosis of endothelial cell of the arterial wall, the macromolecular transport happens surrounding the leaky cells. The arterial wall was divided into four layers: the endothelial layer, the subendothelial intima, the internal elastic lamina and the media for the convenience of research. The time-dependent concentration growth,the effect of the shape of endothelial cell and the effect of physiological parameters were analyzed. The analytical solution of velocity field and pressure field of water flow across the arterial wall were obtained; and concentration distribution of three macromolecules ; LDL,HRP and Albumin, were calculated with numerical simulation method. The new theory predicts, the maximum and distribution areas of time dependent concentration with round shape endothelial cell are both larger than that with ellipse-shape endothelial cell. The model also predicts the concentration growth is much alike that of a two-dimensional model and it shows that the concentration reaches its peak at the leaky junction where atherosclerotic formation frequently occurs and falls down rapidly in a limited area beginning from its earlier time growth to the state when macromolecular transfer approaches steadily. These predictions of the new model are in agreement with the experimental observation for the growth and concentration distribution of LDL and Albumin. 展开更多
关键词 UNSTEADY three-dimensional model flow ACROSS the ARTERIAL wall macromolecular TRANSPORTATION ATHEROSCLEROSIS concentration distribution
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Three-dimensional forward modeling for magnetotelluric sounding by finite element method 被引量:3
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作者 童孝忠 柳建新 +3 位作者 谢维 徐凌华 郭荣文 程云涛 《Journal of Central South University》 SCIE EI CAS 2009年第1期136-142,共7页
A finite element algorithm combined with divergence condition was presented for computing three-dimensional(3D) magnetotelluric forward modeling. The finite element equation of three-dimensional magnetotelluric forwar... A finite element algorithm combined with divergence condition was presented for computing three-dimensional(3D) magnetotelluric forward modeling. The finite element equation of three-dimensional magnetotelluric forward modeling was derived from Maxwell's equations using general variation principle. The divergence condition was added forcedly to the electric field boundary value problem, which made the solution correct. The system of equation of the finite element algorithm was a large sparse, banded, symmetric, ill-conditioned, non-Hermitian complex matrix equation, which can be solved using the Bi-CGSTAB method. In order to prove correctness of the three-dimensional magnetotelluric forward algorithm, the computed results and analytic results of one-dimensional geo-electrical model were compared. In addition, the three-dimensional magnetotelluric forward algorithm is given a further evaluation by computing COMMEMI model. The forward modeling results show that the algorithm is very efficient, and it has a lot of advantages, such as the high precision, the canonical process of solving problem, meeting the internal boundary condition automatically and adapting to all kinds of distribution of multi-substances. 展开更多
关键词 电场 三维大地电磁模拟技术 计算方法 有限元方法 变分原理
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A Three-dimensional Heterogeneous Mass Transfer Model for the Absorption of Gas into Multiphase System 被引量:1
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作者 蔡旺锋 张丹 +1 位作者 许春建 周明 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2005年第6期717-725,共9页
一个三维的异构的传质模型被建议在气体吸收上调查驱散的粒子的改进。计算本地、全面的改进因素的策略被建议。而不是一个全球格子,合成重叠格子被采用,它简化三维的模型方程的安装和解决方案。驱散的粒子停顿,粒子大小,搬运部件的... 一个三维的异构的传质模型被建议在气体吸收上调查驱散的粒子的改进。计算本地、全面的改进因素的策略被建议。而不是一个全球格子,合成重叠格子被采用,它简化三维的模型方程的安装和解决方案。驱散的粒子停顿,粒子大小,搬运部件的液体固体分配系数,典型接触时间,和在粒子 andgas 液体之间的最短的距离连接,这被发现在吸收上有主要影响改进因素。气体吸收和在液膜的搬运部件的径向扩散上的 particle-particleinteraction 我们与多粒子模拟再学习。建议模型相当从文学预言了试验数据很好。 展开更多
关键词 多项体系气体吸收 三维非均传质模型 复合重叠格 增加因子 气液界面
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Three-Dimensional Model Test for Port Engineering with Multi-Directional Waves 被引量:1
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作者 Yu Yuxiu Liu Shuxue Professor, State Key Laboratory of Coastal and Offshore Engineering, Dalian University of Technology (DUT), Dalian 116024 Assistant Researcher, State Key Laboratory of Coastal and Offshore Engineering, DUT, Dalian 116024 《China Ocean Engineering》 SCIE EI 1994年第1期51-66,共16页
-The necessity of using irregular waves, especially multi- directional waves to conduct three-dimensional model tests for port engineering and the test method are described in this paper through an example of model te... -The necessity of using irregular waves, especially multi- directional waves to conduct three-dimensional model tests for port engineering and the test method are described in this paper through an example of model test for a port. The test results show that a deep navigation channel has a large effect on the waves in front of the breakwater near the port entrance and on the wave condition in the port. 展开更多
关键词 port engineering three-dimensional model test irregular waves multi-directional waves
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THREE-DIMENSIONAL MATHEMATICAL MODEL AND ITS APPLICATION IN THE NEIGHBORHOOD OF THE THREE GORGES RESERVOIR DAM IN THE YANGTZE RIVER 被引量:1
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作者 方红卫 Wolfgang Rodi 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2002年第3期235-243,共9页
The calculation of flow and sediment transport is one of the most important tasks in river engineering. The task is particularly difficult because a number of complex physical phenomena should be accounted for more re... The calculation of flow and sediment transport is one of the most important tasks in river engineering. The task is particularly difficult because a number of complex physical phenomena should be accounted for more realistically in a model with a predictive power. Three-dimensional calculations of river flow and suspended sediment transport are performed in this paper with application in the Three Gorges Reservoir in the Yangtze River. A period of 76 years after the dam is built is simulated and the results are compared with laboratory measurements obtained by Tsinghua University whereby the model is verified and calibrated. Generally speaking, the calculated results agree well with the experiments, demonstrating that the present model can be used for flow and sediment transport prediction in rivers. 展开更多
关键词 three-dimensional mathematical model sediment transport three Gorges Project (TGP)
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A Novel Three-Dimensional Mouse Embryonic Implantation Model In Vitro 被引量:2
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作者 SONG Yu-xuan CAO Bin-yun 《Agricultural Sciences in China》 CAS CSCD 2007年第1期115-120,共6页
To regenerate three-dimensional endometrium in vitro as a novel model for studying the mechanism of implantation of embryos, the luminal epithelial cells and stromal cells of the rabbit uterus were separated and cultu... To regenerate three-dimensional endometrium in vitro as a novel model for studying the mechanism of implantation of embryos, the luminal epithelial cells and stromal cells of the rabbit uterus were separated and cultured in vitro. The type Ⅰ mouse tail collagen was used as scaffolding material. The stromal cells were inoculated in the type I mouse tail collagen, and the luminal epithelial cells were inoculated on the type i mouse tall collagen to regenerate the endometrium in vitro. The regenerated endometrium was cultured in DMEM-F/12 media containing 100 nmol L^-1 progesterone, 10 nM β-estradiol, and 10% fetal bovine serum (FBS) for 3 d. The media were then replaced with CZB containing 100 nM progesterone, 10 nmol L-1 β-estradiol, and 10% FBS, and the mouse blastulas were co-cultured with it. The results of scanning electronic micrography showed that the epithelial cells on the surface of the reconstructed endometrium were covered with numerous slender microvilli and some epithelial cells protruded pinopodes. After culturing for 12 h with the mouse blastula, the shedding, attachment, and implantation of the blastula were observed. The blastula can escape from zona pellucida and attach to the three-dimensional endometrium and is then implanted into it. This study showed that the reconstructed three-dimensional endometrium can serve as a robust embryo implantation model in vitro. 展开更多
关键词 three-dimensional endometrium EMBRYO IMPLANTATION model in vitro
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Numerical Simulation of Saline Intrusion and Purging in Long SeaOutfalls with Three-Dimensional Model 被引量:1
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作者 吴玮 严忠民 吴龙华 《China Ocean Engineering》 SCIE EI 2006年第2期279-288,共10页
Saline intrusion into marine sewage ouffalls will greatly decrease the efficiency of sewage disposal. In order to investigate the mechanisms of this flow, in this paper, a three-dimensional numerical model based on F... Saline intrusion into marine sewage ouffalls will greatly decrease the efficiency of sewage disposal. In order to investigate the mechanisms of this flow, in this paper, a three-dimensional numerical model based on FVM (Finite Volume Method) is established, The RNG κ-ε model is selected for turbulence modeling. The time-averaged vohtme fraction equations are introduced to simulate the stratification and inteffaeial exchange of sewage and seawater in outfalls. Validity of the established three-dimensional numerical model is evaluated by comparisons of numerical results with experimental data. With this three-dimensional numerical model, the internal flow characteristics in ouffalls for different sewage discharges are simulated. The results indicate that for a low sewage discharge, saline circulates in the outfall due to intrusion and both the inflowing momentum and the inteffaeial turbulent mixing are important mechanisms to extrude the saline. For a high sewage discharge, saline intrusion could be avoided. The inflow momentum is the main mechanism to extrude the saline and the inteffacial turbulent mixing is nut important relatively. Even at a high sewage discharge, the saline wedge would be retained in the main ouffall pipe after the risers are purged. It takes a long time for this saline wedge to be extruded by interracial turbulent mixing. 展开更多
关键词 sea outfalls saline intrusion saline purging three-dimensional numerical model experimental study
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Three-Dimension Mathematical Model of Total Phosphor in the Reservoir and Application 被引量:2
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作者 NIEJing YANGTian-xing LIUXiao-duan 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2004年第3期294-298,共5页
Taking the transport of total phosphor pollutants in the Beijing Miyun reservoir for example,we have obtained three dimensional distributing regularity of total phosphor pollutants by the calculation of the linear int... Taking the transport of total phosphor pollutants in the Beijing Miyun reservoir for example,we have obtained three dimensional distributing regularity of total phosphor pollutants by the calculation of the linear interpolation value of each point between horizontal layers. The credibility analysis in allusion to this method was carried out and the programming scheme for realizing this method was set forth. 展开更多
关键词 Water body Total phosphor three dimensional mathematical model
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Research on dynamic updating of three dimensional geological modeling based on the OO-Solid model 被引量:1
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作者 侯恩科 邓念东 +1 位作者 张志华 赵洲 《Journal of Coal Science & Engineering(China)》 2008年第3期420-424,共5页
The dynamic updating of the model included: the change of space border,addi- tion and reduction of spatial component (disappearing,dividing and merging),the change of the topological relationship and synchronous dynam... The dynamic updating of the model included: the change of space border,addi- tion and reduction of spatial component (disappearing,dividing and merging),the change of the topological relationship and synchronous dynamic updating of database.Firstly, arming at the deficiency of OO-Solid model in the aspect of dynamic updating,modeling primitives of OO-Solid model were modified.And then the algorithms of dynamic updating of 3D geological model with the node data,line data or surface data change were dis- cussed.The core algorithms was done by establishing space index,following the way of facing the object from bottom to top,namely the dynamic updating from the node to arc, and then to polygon,then to the face of the component and finally to the geological object. The research has important theoretical and practical values in the field of three dimen- sional geological modeling and is significant in the field of mineral resources. 展开更多
关键词 数字化煤矿 三维地质模式 煤炭开采 采煤方法
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Development of a Percentile Based Three-dimensional Model of the Buttocks in Computer System 被引量:2
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作者 WANG Lijing HE Xueli LI Hongpeng 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2016年第3期633-640,共8页
There are diverse products related to human buttocks, which need to be designed, manufactured and evaluated with 3D buttock model. The 3D buttock model used in present research field is just simple approximate model s... There are diverse products related to human buttocks, which need to be designed, manufactured and evaluated with 3D buttock model. The 3D buttock model used in present research field is just simple approximate model similar to human buttocks. The 3D buttock percentile model is highly desired in the ergonomics design and evaluation for these products. So far, there is no research on the percentile sizing system of human 3D buttock model. So the purpose of this paper is to develop a new method for building three-dimensional buttock percentile model in computer system. After scanning the 3D shape of buttocks, the cloud data of 3D points is imported into the reverse engineering software(Geomagic) for the reconstructing of the buttock surface model. Five characteristic dimensions of the buttock are measured through mark-points after models being imported into engineering software CATIA. A series of space points are obtained by the intersecting of the cutting slices and 3D buttock surface model, and then are ordered based on the sequence number of the horizontal and vertical slices. The 1st, 5th, 50 th, 95 th, 99 th percentile values of the five dimensions and the spatial coordinate values of the space points are obtained, and used to reconstruct percentile buttock models. This research proposes a establishing method of percentile sizing system of buttock 3D model based on the percentile values of the ischial tuberosities diameter, the distances from margin to ischial tuberosity and the space coordinates value of coordinate points, for establishing the Nth percentile 3D buttock model and every special buttock types model. The proposed method also serves as a useful guidance for the other 3D percentile models establishment for other part in human body with characteristic points. 展开更多
关键词 three-dimensional percentile buttock model point-cloud
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Modeling and validating three dimensional human normal cervix and cervical cancer tissues in vitro 被引量:1
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作者 Anna Karolina Zuk Xuesong Wen +2 位作者 Stephen Dilworth Dong Li Lucy Ghali 《The Journal of Biomedical Research》 CAS CSCD 2017年第3期240-247,共8页
The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and ca... The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and cancerous cervical tissue.Normal epithelial and immortalized cervical epithelial carcinoma cell lines were used to construct 3-D artificial normal cervical and cervical cancerous tissues.De-epidermised dermis(DED) was used as a scaffold for both models.Morphological analyses were conducted by using hematoxylin and eosin staining and characteristics of the models were studied by analyzing the expression of different structural cytokeratins and differential protein marker MAX dimerisation protein 1(Mad1) using immunohistochemical technique.Haematoxylin and eosin staining results showed that normal cervical tissue had multi epithelial layers while cancerous cervical tissue showed dysplastic changes.Immunohistochemistry staining revealed that for normal cervix model cytokeratin 10 was expressed in the upper stratified layer of the epithelium while cytokeratin 5 was expressed mainly in the middle and basal layer.Cytokeratin 19 was weakly expressed in a few basal cells.Cervical cancer model showed cytokeratin 19 expression in different epithelial layers and weak or no expression for cytokeratin 5 and cytokeratin 10.Madl expression was detected in some suprabasal cells.The 3-D in vitro models showed stratified epithelial layers and expressed the same types and patterns of differentiation marker proteins as seen in corresponding in vivo tissue in either normal cervical or cervical cancerous tissue.These findings imply that they can serve as functional normal and cervical cancer models. 展开更多
关键词 cervical cancer MAX dimerisation protein 1 CYTOKERATINS three dimensional in vitro models
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Simulation-Based Construction of Three-Dimensional Process Model for Punching Cartridge Cases 被引量:1
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作者 Zhifang Wei Yechang Hu +1 位作者 Wu Lyu Jianzhong Gao 《Journal of Beijing Institute of Technology》 EI CAS 2018年第2期276-284,共9页
A method of constructing three-dimensional process model for the punching cartridge cases is presented based on DEFORM simulation analysis. Using DEFORM software,the finite element simulation models for the punching a... A method of constructing three-dimensional process model for the punching cartridge cases is presented based on DEFORM simulation analysis. Using DEFORM software,the finite element simulation models for the punching and forming process of cartridge cases are established,and the corresponding simulation result model of each intermediate procedure is obtained by continuously performing the forming process simulation. The simulation model cannot annotate size and process information due to poor interface between DEFORM software and CAD software. Thus,a 3D annotation module is developed with secondary development technology of UG NX software. Consequently,the final process model with dimension and process information is obtained. Then,with the current 3D process management system,the 3D punching and forming process design of cartridge cases can be completed further. An example is also provided to illustrate that the relative error between the simulation process model and the physical model is less than 2%,which proves the validity and reliability of the proposed method in this study. 展开更多
关键词 punching three-dimensional process model finite element simulation three-dimensional annotation
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Construction and Analysis of Three-dimensional Graphic Model of Single-chain Fv Derived from an Anti-human Placental Acidic Isoferritin Monoclonal Antibody by Computer 被引量:3
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作者 周春 沈关心 +4 位作者 朱慧芬 杨静 张悦 冯健南 沈倍奋 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2000年第1期23-25,共3页
Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein... Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein-predicting computer algorithm on Silicon graphic computer station. The structure, surface static electricity and hydrophobicity of scFv were investigated. Computer graphic modelling indicated that all regions of scFv including the linker, variable regions of the heavy (VH) and light (VL) chains were suitable. The VH region and the VL region were involved in composing the 'hydrophobic pocket'. The linker was drifted away VH and VL regions. The complementarity determining regions (CDRs) of VH and VL regions surrounded the 'hydrophobic pocket'. This study provides a theory basis for improving antibody affinity, investigating antibody structure and analyzing the functions of VH and VL regions in antibody activity. 展开更多
关键词 placental acidic isoferritin single-chain Fv three-dimensional structure com- puter modelling
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Research on the Three-dimensional Modeling and Optimization of a Virtual Tower Crane Based on 3DS Max, Solidworks and EON Professional 被引量:2
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作者 HOU Xiao-ting LI Chang-hua 《International Journal of Plant Engineering and Management》 2013年第1期15-19,共5页
Three-dimensional modeling of virtual hoisting machinery is the critical works to structure the system of virtual construction, and the foundation to realize intelligent and interactive virtual hoisting. Aimed at enha... Three-dimensional modeling of virtual hoisting machinery is the critical works to structure the system of virtual construction, and the foundation to realize intelligent and interactive virtual hoisting. Aimed at enhancing the requests of image quality and stability of the virtual construction scene, taking a tower crane for example. We studied the technology of three-dimensional modeling and optimization of a virtual tower crane, and a method named two-stage model optimization was put forward. This depended on the modeling stage using Solidworks and 3DS Max and the performance optimization stage in EON. The practice of software development indicates that the proposed methods of three-dimensional modeling and optimization could satisfy the performance request of virtual construction system and be popularized to other virtual system. 展开更多
关键词 3DS Max SOLIDWORKS EON Professional virtual tower crane three-dimensional modeling andoptimization virtual construction
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Three-dimensional tidal current numerical model of the Oujiang Estuary 被引量:2
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作者 LI Mengguo LI Wendan 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2009年第3期17-25,共9页
The characteristics of three-dimensional (3-D) tidal current in the Oujiang Estuary are investigated according to in situ observations. The Oujiang Estuary has features of irregular coastline, complex topography, ma... The characteristics of three-dimensional (3-D) tidal current in the Oujiang Estuary are investigated according to in situ observations. The Oujiang Estuary has features of irregular coastline, complex topography, many islands, moveable boundary, and submerged dyke, therefore, σ 3-D numerical model oil an unstructured triangular grid has been degeloped. The σ coordinate transforination, the moveable boundary and submerged dyke treatment techniques were employed in the model so it is suitable for the tidal simulations in the Oujing Estuary with submerged dyke and moveable boundary problems. The model is evaluated with the in situ data, and the results show that the calculated water elevations at 19 stations and currents at 19 profiler stations are in good agreement with measured data both in magnitude and phase. This numerical model is applied to the 3-D tidal circulation simulations of experiments in stopping flow transport through the South Branch of the Oujiang Estuary, and the feasibility to cutoff the flow in the South Branch of the Oujiang Estuary is demonstrated by numerical simulation experiments. The developed numerical model simulated the 3-D tidal current circulations in complicated coastal and estuarine waters very well. 展开更多
关键词 Oujiang Estuary three-dimensional tidal current mathematical model numerical simulation triangular grid σ coordinate transformation
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Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling 被引量:7
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作者 Nipha Chaicharoenaudomrung Phongsakorn Kunhorm Parinya Noisa 《World Journal of Stem Cells》 SCIE 2019年第12期1065-1083,共19页
Three-dimensional(3D)culture systems are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than the monolayer cultures.In cancer and stem cell research,the natural cel... Three-dimensional(3D)culture systems are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than the monolayer cultures.In cancer and stem cell research,the natural cell characteristics and architectures are closely mimicked by the 3D cell models.Thus,the 3D cell cultures are promising and suitable systems for various proposes,ranging from disease modeling to drug target identification as well as potential therapeutic substances that may transform our lives.This review provides a comprehensive compendium of recent advancements in culturing cells,in particular cancer and stem cells,using 3D culture techniques.The major approaches highlighted here include cell spheroids,hydrogel embedding,bioreactors,scaffolds,and bioprinting.In addition,the progress of employing 3D cell culture systems as a platform for cancer and stem cell research was addressed,and the prominent studies of 3D cell culture systems were discussed. 展开更多
关键词 three-dimensional CULTURES CANCER Stem cells Disease modelING In VITRO screening PLATFORM
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