Analysis of Technical Intelligence of Tumor Cell Therapy Based on Patent Map

Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent data in the field of tumor cell therapy in China,the patent map method was used to construct a scientific technical information analysis model.Then,the technical status of new drug research and development in this field was explored to identify technical opportunities.Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage.The technical innovation regions are mainly distributed in the east and innovative entities are enterprises.Technology hotspots are concentrated in areas such as A61P35,C12N5,and the patented technical efficacy is high.Besides,the technical research and development opportunities identified are closely related to the background in this field.To better promote the development of the industry,enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile,they should pay attention to technical efficacy analysis to identify more technical opportunities,thereby effectively guiding innovation strategic decisions.

Asymmetric image encryption algorithm based on a new three-dimensional improved logistic chaotic map

Based on some analyses of existing chaotic image encryption frameworks and a new designed three-dimensional improved logistic chaotic map(3D-ILM),an asymmetric image encryption algorithm using public-key Rivest–Shamir–Adleman(RSA)is presented in this paper.In the first stage,a new 3D-ILM is proposed to enhance the chaotic behavior considering analysis of time sequence,Lyapunov exponent,and Shannon entropy.In the second stage,combined with the public key RSA algorithm,a new key acquisition mathematical model(MKA)is constructed to obtain the initial keys for the 3D-ILM.Consequently,the key stream can be produced depending on the plain image for a higher security.Moreover,a novel process model(NPM)for the input of the 3D-ILM is built,which is built to improve the distribution uniformity of the chaotic sequence.In the third stage,to encrypt the plain image,a pre-process by exclusive OR(XOR)operation with a random matrix is applied.Then,the pre-processed image is performed by a permutation for rows,a downward modulo function for adjacent pixels,a permutation for columns,a forward direction XOR addition-modulo diffusion,and a backward direction XOR addition-modulo diffusion to achieve the final cipher image.Moreover,experiments show that the the proposed algorithm has a better performance.Especially,the number of pixels change rate(NPCR)is close to ideal case 99.6094%,with the unified average changing intensity(UACI)close to 33.4634%,and the information entropy(IE)close to 8.

Design and Realization of Block Level Augmented Reality Three-Dimensional Map

In response to the construction needs of “Real 3D China”, the system structure, functional framework, application direction and product form of block level augmented reality three-dimensional map is designed. Those provide references and ideas for the later large-scale production of augmented reality three-dimensional map. The augmented reality three-dimensional map is produced based on skyline software. Including the map browsing, measurement and analysis and so on, the basic function of three-dimensional map is realized. The special functional module including housing management, pipeline management and so on is developed combining the need of residential quarters development, that expands the application fields of augmented reality three-dimensional map. Those lay the groundwork for the application of augmented reality three-dimensional map. .

A modified method of discontinuity trace mapping using three-dimensional point clouds of rock mass surfaces

This paper presents an automated method for discontinuity trace mapping using three-dimensional point clouds of rock mass surfaces.Specifically,the method consists of five steps:(1)detection of trace feature points by normal tensor voting theory,(2)co ntraction of trace feature points,(3)connection of trace feature points,(4)linearization of trace segments,and(5)connection of trace segments.A sensitivity analysis was then conducted to identify the optimal parameters of the proposed method.Three field cases,a natural rock mass outcrop and two excavated rock tunnel surfaces,were analyzed using the proposed method to evaluate its validity and efficiency.The results show that the proposed method is more efficient and accurate than the traditional trace mapping method,and the efficiency enhancement is more robust as the number of feature points increases.

Three-dimensional computed tomography mapping of posterior malleolar fractures

BACKGROUND Posterior malleolar fractures have been reported to occur in<40%of ankle fractures.AIM To reveal the recurrent patterns and characteristics of posterior malleolar fractures by creating fracture maps of the posterior malleolar fractures through the use of computed tomography mapping.METHODS A consecutive series of posterior malleolar fractures was used to create threedimensional reconstruction images,which were oriented and superimposed to fit an ankle model template by both aligning specific biolandmarks and reducing reconstructed fracture fragments.Fracture lines were found and traced in order to generate an ankle fracture map.RESULTS This study involved 112 patients with a mean age of 49,comprising 32 pronationexternal rotation grade IV fractures and 80 supination-external rotation grade IV fractures according to the Lauge-Hansen classification system.Three-dimensional maps showed that the posterior ankle fracture fragments in the supinationexternal rotation grade IV group were relatively smaller than those in the pronation-external rotation grade IV group after posterior malleolus fracture.In addition,the distribution analyses on posterior malleolus fracture lines indicated that the supination-external rotation grade IV group tended to have higher linear density but more concentrated and orderly distribution fractures compared to the pronation-external rotation grade IV group.CONCLUSION Fracture maps revealed the fracture characteristics and recurrent patterns of posterior malleolar fractures,which might help to improve the understanding of ankle fracture as well as increase opportunities for follow-up research and aid clinical decision-making.

Application of Three-dimensional Laser Scanning Technology in the Teaching Practice of Surveying and Mapping of Ancient Buildings

Based on the study of the application of three-dimensional laser scanning technology in ancient building surveying and mapping,this paper briefly describes the working principle and flow of three-dimensional laser scanning technology.Based on the practical application,this paper puts forward the discussion of related problems and matters needing attention.This has a certain reference significance for the study of new technology in surveying and mapping of ancient buildings.

Balanced Functional Maps for Three-Dimensional Non-Rigid Shape Registration

Three-dimensional(3D)shape registration is a challenging problem,especially for shapes under non-rigid transformations.In this paper,a 3D non-rigid shape registration method is proposed,called balanced functional maps(BFM).The BFM algorithm generalizes the point-based correspondence to functions.By choosing the Laplace-Beltrami eigenfunctions as the function basis,the transformations between shapes can be represented by the functional map(FM)matrix.In addition,many constraints on shape registration,such as the feature descriptor,keypoint,and salient region correspondence,can be formulated linearly using the matrix.By bi-directionally searching for the nearest neighbors of points’indicator functions in the function space,the point-based correspondence can be derived from FMs.We conducted several experiments on the Topology and Orchestration Specification for Cloud Applications(TOSCA)dataset and the Shape Completion and Animation of People(SCAPE)dataset.Experimental results show that the proposed BFM algorithm is effective and has superior performance than the state-of-the-art methods on both datasets.

利用MapGIS编绘地质图的一些技巧

以数字化地质图为例,从数据输入、数据处理两方面入手,结合实践经验,详细阐述了运用MapGIS数字化地质图时的一些关键技术,主要包括图件的输入、分层矢量化的输入、图形编辑、误差校正,拓扑造面、地质面色的自动替换。

中国个人信息保护应用与技术进展研究——基于科学知识图谱视角

[目的/意义]大数据时代,公众对个人信息保护的需求日渐多维化,基于科学知识图谱视角分析近十年中国个人信息保护演化趋势与前沿热点有其必要性。[方法/过程]基于文献计量、突现检测、科学知识图谱等多种方式展开分析,以CSSCI和CSCD刊源分别表征应用与技术维度,梳理近十年国内个人信息保护研究的双维度发展趋势。[结果/结论]我国个人信息保护研究文献数量呈现阶段性增长模式;个人、机构的合作方式以内部学术交流、地域性联系为主,多学科交叉格局有待形成;在应用维度上以图情类主导、公共化、数字化为研究趋势;在技术维度上以计算机类主导、精细化、智能化为研究趋势。全民监督与数据共治成为应对大数据时代个人信息保护新挑战的可行之策。

GIS数字测绘技术在矿山地质测量工作中的应用

为实现矿山地质数字化测绘,保证矿山地质测量结果的精确性和可靠性,首先介绍GIS数字测绘技术定义和特性;其次,将三维GIS数字测绘技术、空间可视化技术、空间导向技术科学地应用于矿山地质测量工作中;最后,设计基于GIS的矿山地质测量信息系统。设计实践结果表明:基于GIS的矿山地质测量信息系统具有空间数据共享及时、地质信息测量精确等特点,为矿山地质测量工作开展提供重要的技术支持。希望通过这次研究,为相关人员提供有效的借鉴和参考。

地理实体与地形图数据一体化采集方法

分析了地理实体与地形图的建设内容和数据结构,从生产数据分类和模型设计、定制生产模板及相关实体化需求功能、资料利用、数据生产以及数据质检等技术流程方面进行探讨,研究了一整套可行的地理实体与地形图数据一体化采集方法。

DEM测绘精度评价及误差分析

探讨DEM测绘精度评价及误差分析的相关问题,本文通过对现有文献的分析,总结出了一系列解决方案,以提高DEM测绘的准确性和可靠性。通过本文的研究,可以更好地理解DEM测绘的技术原理和应用方法,为各行业提供更加精准的空间数据支持。

测绘技术在地质找矿领域的运用探析

在地质测绘与找矿领域中应用测绘技术,能够有效提高地质测量准确性,加快找矿效率,为工程项目的建设质量与安全提供可靠保障,切实降低工程成本投入。基于此,本文将以地质找矿行业为背景,围绕测绘技术应用展开研究,首先对测绘技术概念进行具体阐述,然后论述当下地质测绘中的关键问题,最后从几个方面出发,提出关于地质找矿领域中测绘技术的具体应用路径,旨在发挥技术应用价值,为地质测绘与找矿提供技术支撑,进一步提高地质找矿效率,以期为相关人士提供有效参考。

零部件测绘与CAD成图技术赛项与中职机械制图教学融合的研究

该文采用定性分析和案例研究的方法,探讨零部件测绘与CAD成图技术赛项与中等职业技术学校机械制图教学的融合方式,重点分析了CAD技术在现代机械制图教育中的应用及其对学生技能发展的影响及CAD技术在教学中的实际应用情况,阐述如何将竞赛中的先进测绘技术整合到课程教学中,以提高学生的实际操作能力和创新思维。研究结果旨在揭示中职机械制图教学与行业需求融合的可能性和有效路径,为提升学生的技术技能、创新能力和就业竞争力提供实际指导。

基于北斗定位技术的铁路企业公务用车管理系统

为加强铁路企业公务用车管理工作,更好地服务铁路运输生产,开发了基于北斗定位技术的铁路企业公务用车管理系统。在实现公务车辆和驾驶员台账集中管理、实行公务车辆配备/配属/租用业务统一管理的基础上,该系统设计了高效、灵活、合规的用车申请与合并派车处理流程,可自动判别和处理加油卡违规使用行为,提供基于电子地图服务的车辆定位及车辆运行监控功能。该系统已在中国铁路兰州局集团有限公司(简称:兰州局)试点应用,方便铁路局全体职工获取公务用车服务,有助于提高车辆利用率,提升了铁路企业公务用车规范化、数字化管理水平。

矿山井下测绘资料管理探讨

在矿山井下生产过程中,矿山井下测绘在保障均衡生产、合理开采地下资源以及确保采掘工程质量和安全生产等方面的作用至关重要。抓好矿山井下测绘管理工作,只有建立科学的管理体系,采取合理的操作流程,并加强对矿山井下测绘资料的收集、整理、分类和管理等方面的工作,才能真正提高矿山井下测绘工作的效率和质量,从而实现矿山井下生产的可持续发展。

新时期测绘地理信息与自然资源管理深度融合研究

随着科技的进步和社会的发展,测绘地理信息与自然资源管理在国家治理体系和生态文明建设中的地位日益凸显。新时期,如何推动测绘地理信息与自然资源管理的深度融合,提高自然资源管理效能,成为当前面临的重要课题。文章从政策法规、技术手段、管理体制等方面进行深入剖析,为测绘地理信息与自然资源管理的深度融合提供理论指导和实践借鉴。

MapInfo环境符号库扩充的技术途径和方法研究

分析了MapInfo符号库扩充原理及方法,结合地形图点、线、面符号的特点,给出一组符号制作的具体实例。同时对MapInfo文字符号的制作进行分析研究,提出将文字矢量化为图形后再加入MapInfo符号数据库中的方法,并通过具体实例验证了此方法的可行性。

Initial experience with circumferential pulmonary vein ablation guided by fusion of magnetic resonance imaging with three-dimensional electroanatomic mapping

Catheter ablation for the treatment of atrial fibrillation （AF） has been a focal target ofelectrophysiological study in recent years. Up to date, circumferential pulmonary vein ablation （CPVA） guided by three-dimensional （3-D） electreanatomic mapping （Carto, USA） has been one of the most favourable procedures for the treatment of AF. However, it is still difficult to acquire the detailed information on number, location, and branching pattern of all pulmonary veins （PVs） when the 3-D electroanatomic mapping system is used alone.

1000kt/a粒状DAP联产200kt/a粉状MAP扩能方案剖析

某 30 0kt/a(P2 O5计 )磷酸、40 0× 2kt/a重过磷酸钙 (TSP)装置 ,为适应市场需求 ,将一套 40 0kt/aTSP和 30 0kt/a磷酸装置采用传统的磷酸浓缩工艺 ,改造为 6 0 0kt/aDAP装置 ,试生产成功、基本达到设计能力后 ,拟利用仍闲置的 40 0kt/aTSP ,并扩建一套 30 0kt/a磷酸装置 ,实现磷酸铵产量翻番的目标。针对传统的磷酸浓缩工艺生产DAP受系统水平衡制约 ,要求浓磷酸中ω(P2 O5)≥ 48% ,浓缩系统加热器中列管易结垢 ,DAP装置中尾气洗涤系统的开车率也欠高 ,扩能方案拟采用传统的磷酸浓缩工艺与中和料浆浓缩工艺相结合的新工艺 ,实现主产粒状DAP、联产粉状MAP ,磷酸铵产量翻番。分析了利用该新工艺生产磷酸铵的优点 ,指出其在实现磷酸铵产量翻番中投资省、能耗低、操作稳定性高 ,并可消化利用本系统磷酸淤渣、含磷废渣 ,也为今后调整产品品种、进一步挖潜改造留有余地。