The three-dimensional teaching mode is an integrated teaching mode,which integrates teaching design,teaching methods,teaching resources and student learning.In the English classroom,the three-dimensional teaching mode...The three-dimensional teaching mode is an integrated teaching mode,which integrates teaching design,teaching methods,teaching resources and student learning.In the English classroom,the three-dimensional teaching mode is used to make the English learning class full of vitality and to improve the effect of English classroom teaching.展开更多
Purpose:Study the specific application effect of multi-dimensional and three-dimensional teaching in Geriatric Nursing teaching in the context of mass entrepreneurship and innovation.Methods:Respectively select 80 nur...Purpose:Study the specific application effect of multi-dimensional and three-dimensional teaching in Geriatric Nursing teaching in the context of mass entrepreneurship and innovation.Methods:Respectively select 80 nursing undergraduates of 2015 and 80 nursing undergraduates of 2014 in our school as the research object of the experimental group and the control group.In terms of Geriatric Nursing teaching,nursing students in the control group adopt traditional classroom teaching methods to carry out,while students in the experimental group adopt multi-dimensional and three-dimensional teaching in the context of mass entrepreneurship and innovation.Then observe and compare the geriatric nursing knowledge scoring as well as theory and practice assessment results in the two groups taught with different methods.Results:It's obvious that the scoring of nursing students in the experimental group is higher than those in the control group in respect of geriatric nursing knowledge,and statistical significance exists in the between-group differences(P<0.05).The nursing students in the experimental group perform obviously better than those in the control group in terms of the results of theory,practice and comprehensive assessment as well as total score,and statistical significance exists in the between-group differences(P<0.05).Conclusion:Implementing Geriatric Nursing teaching for higher education nursing undergraduates with multi-dimensional and three-dimensional teaching in the context of mass entrepreneurship and innovation can remarkably improve nursing students'cognitive level in geriatric nursing as well as their mastery degree of theoretical,practical and comprehensive knowledge.Thus,the multi-dimensional and three-dimensional teaching mode in the context of mass entrepreneurship and innovation makes 80 nursing undergraduates of 2015 in our school direct beneficiaries,which could be popularized and applied in medical colleges.展开更多
The paper discusses the application of three-dimensional textbook in English teaching. The three-dimensional textbook plays an incomparable function than the traditional textbook and thus has an extensive application ...The paper discusses the application of three-dimensional textbook in English teaching. The three-dimensional textbook plays an incomparable function than the traditional textbook and thus has an extensive application in the college English education. It demonstrates the application through the usage of the three-dimensional textbook in the real teaching and shows that excessive usage of sound and pictures or drawings may distract the attention of students. It raises several suggestions at the end.展开更多
The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model...The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model currently is mainly discussed. Meanwhile, the dynamic internal composition of the "three-dimensional teaching" is mainly introduced from its three stages and three principles, and also the three-dimensional teaching reform plan is supported and promoted based on two advantages.展开更多
By analyzing the dilemma encountered in practical teaching of new media advertising course in the digital economy era, this paper explores the teaching path of new media advertising course based on “three-dimensional...By analyzing the dilemma encountered in practical teaching of new media advertising course in the digital economy era, this paper explores the teaching path of new media advertising course based on “three-dimensional” practical teaching system, and believes that it is necessary to accurately determine talent training objectives, and construct the three dimensions of practical teaching, practical ability, and new media entrepreneurship and employment. Finally, the teaching countermeasures of practical teaching system based on three dimensions are put forward.展开更多
AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulati...AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulating the movement of the ocular and the extraocular muscles according to Sherrington’s law. The model with joint bearing was to ensure the flexibility and centripetal rotation of the simulated ball and stepper motor as the driving device. A programmable processor was used to control the motion amplitude of the stepper motor. The size of hole was set at the back of the simulated shell to limit the amount of eye movement. Afterwards, using a 5-point Likert scale, 7 experts evaluated the 3D electric ophthalmotrope’s simulation ability and precision, compared with the traditional anatomical model. In addition, the teaching effectiveness of the 3D electric ophthalmotrope was evaluated at in-class quiz and final exam in a randomized controlled trial. RESULTS: The 3D electric ophthalmotrope could be operated easily to demonstrate the eye movements with motion of different ocular muscles. The experts agreed that the 3D electric ophthalmotrope was different from the traditional model and was easier for students to understand every extraocular muscles’ movement in each evaluation index(P<0.05). Moreover, the results of teaching effectiveness showed that the 3D electric ophthalmotrope were significantly greater than the traditional model both at in-class quiz(P<0.01) and final exam(P<0.05). CONCLUSION: This novel 3D electric ophthalmotrope is better than the traditional model, which can be to improve the ophthalmology teaching effectiveness for students to understand the extraocular muscles’ movement.展开更多
Talent cultivation is the primary task of universities.Local general undergraduate colleges and universities should adhere to the basic guidelines of systematization,practicality and integration,continuously explore t...Talent cultivation is the primary task of universities.Local general undergraduate colleges and universities should adhere to the basic guidelines of systematization,practicality and integration,continuously explore the concept of"studentcentered"talent cultivation,and build a threedimensional practical teaching system from three aspects:strengthening the planning and design of the three-dimensional practical teaching system;building an internal and external practical teaching platform;and improving the evaluation and guarantee system of practical teaching quality.The system of practical teaching quality evaluation and guarantee is improved.In order to improve the cultivation ability of applied talents in all aspects.展开更多
Taking contents of Italian Renaissance gardens in the course Foreign Landscape Architecture History as an example,this paper introduces case teaching method and analyzes application of three-dimensional graphic analys...Taking contents of Italian Renaissance gardens in the course Foreign Landscape Architecture History as an example,this paper introduces case teaching method and analyzes application of three-dimensional graphic analysis method in case teaching in detail,aiming at typical cases of Italian Renaissance gardens,namely,Villa Medici,Fiesole and Villa d’Este,Tivoli.Three-dimensional graphic analysis can help students form intuitive feeling of terrain and space,further understand the typical gardening techniques of foreign gardens,so as to improve the teaching effect of landscape architecture history course.展开更多
It can be seen that it is of great practical signi? cance to evaluate practice teaching of tourism management specialty. Tourism management professional ability training objectives that is mainly refers to develop th...It can be seen that it is of great practical signi? cance to evaluate practice teaching of tourism management specialty. Tourism management professional ability training objectives that is mainly refers to develop the tourism, ecology, tourism economics, tourism planning and development, management of travel agencies, tour guides, hotel management and tourism scenic spot management expertise, has complete professional ability has a skilled job skills in tourism industry to cultivate specialized personnel with high quality. The new local colleges and universities as an important role in higher education, entrepreneurship education in the process of exploring the important role of the gradually emerging and to explore the development of the entrepreneurship education in new local colleges and universities will help to cultivate pioneering talents extensively. This paper analyzes the issue from the essential perspective that will improve the general quality of the education.展开更多
Based on the study of the application of three-dimensional laser scanning technology in ancient building surveying and mapping,this paper briefly describes the working principle and flow of three-dimensional laser sca...Based on the study of the application of three-dimensional laser scanning technology in ancient building surveying and mapping,this paper briefly describes the working principle and flow of three-dimensional laser scanning technology.Based on the practical application,this paper puts forward the discussion of related problems and matters needing attention.This has a certain reference significance for the study of new technology in surveying and mapping of ancient buildings.展开更多
Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transfo...Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transformation.This transformation is still ongoing.In order to explain this phenomenon,we establish a three-dimension analysis framework of"ECONOMIC BASE-INFORMATION TECHNOLOGY-CULTURE".All kinds of logics involved in them are closely linked,thus influencing each other.At the same time,these aspects constantly affect the historical trajectory of the evolution.Based on the above analysis framework,the paper uses the historical approach to expound the evolution path on teaching methods in China since ancient times and divides it into four stages.Combined with the practical problems and interview results,we rethink the present information teaching methods.In the end,some suggestions are put forward in order to promote the further development of education-related fields.展开更多
Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding throu...Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding through-thickness assumptions of the field variables are made,and the governing equations are two-dimensional,with the displacements and microrotations of the mid-plane as the unknowns.Once the deformation of the mid-plane is solved,a three-dimensional micropolar elastic field within the plate is generated,which is exact up to the second order except in the boundary region close to the plate edge.As an illustrative example,the bending of a clamped infinitely long plate caused by a uniformly distributed transverse force is analyzed and discussed in detail.展开更多
Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor ...Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor cells.This study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I collagen.It also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and migration.Finally,it compares two-dimensional(2D)and 3D cultures.For comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D model.Besides,the two models yielded significantly different cell morphologies.Finally,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D model.These results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture systems.The developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.展开更多
Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising ap...Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements.This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure.Here,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure.Furthermore,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical applications.The collective insights presented herein highlight the significance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.展开更多
BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional mul...BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.展开更多
Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and t...Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and the generation of new scars can make it very difficult for the impaired nervous system to restore its neural functionality.Traditional treatments can only alleviate secondary injuries but cannot fundamentally repair the spinal cord.Consequently,there is a critical need to develop new treatments to promote functional repair after spinal cord injury.Over recent years,there have been seve ral developments in the use of stem cell therapy for the treatment of spinal cord injury.Alongside significant developments in the field of tissue engineering,three-dimensional bioprinting technology has become a hot research topic due to its ability to accurately print complex structures.This led to the loading of three-dimensional bioprinting scaffolds which provided precise cell localization.These three-dimensional bioprinting scaffolds co uld repair damaged neural circuits and had the potential to repair the damaged spinal cord.In this review,we discuss the mechanisms underlying simple stem cell therapy,the application of different types of stem cells for the treatment of spinal cord injury,and the different manufa cturing methods for three-dimensional bioprinting scaffolds.In particular,we focus on the development of three-dimensional bioprinting scaffolds for the treatment of spinal cord injury.展开更多
ObjectiveThis study aimed to explore the applications of three-dimensional (3D) technology, including virtual reality, augmented reality (AR), and 3D printing system, in the field of medicine, particularly in renal in...ObjectiveThis study aimed to explore the applications of three-dimensional (3D) technology, including virtual reality, augmented reality (AR), and 3D printing system, in the field of medicine, particularly in renal interventions for cancer treatment.MethodsA specialized software transforms 2D medical images into precise 3D digital models, facilitating improved anatomical understanding and surgical planning. Patient-specific 3D printed anatomical models are utilized for preoperative planning, intraoperative guidance, and surgical education. AR technology enables the overlay of digital perceptions onto real-world surgical environments.ResultsPatient-specific 3D printed anatomical models have multiple applications, such as preoperative planning, intraoperative guidance, trainee education, and patient counseling. Virtual reality involves substituting the real world with a computer-generated 3D environment, while AR overlays digitally created perceptions onto the existing reality. The advances in 3D modeling technology have sparked considerable interest in their application to partial nephrectomy in the realm of renal cancer. 3D printing, also known as additive manufacturing, constructs 3D objects based on computer-aided design or digital 3D models. Utilizing 3D-printed preoperative renal models provides benefits for surgical planning, offering a more reliable assessment of the tumor's relationship with vital anatomical structures and enabling better preparation for procedures. AR technology allows surgeons to visualize patient-specific renal anatomical structures and their spatial relationships with surrounding organs by projecting CT/MRI images onto a live laparoscopic video. Incorporating patient-specific 3D digital models into healthcare enhances best practice, resulting in improved patient care, increased patient satisfaction, and cost saving for the healthcare system.展开更多
In recent years,notable progress has been achieved in both the hardware and algorithms of structured illumination microscopy(SIM).Nevertheless,the advancement of three-dimensional structured illumination microscopy(3D...In recent years,notable progress has been achieved in both the hardware and algorithms of structured illumination microscopy(SIM).Nevertheless,the advancement of three-dimensional structured illumination microscopy(3DSIM)has been impeded by challenges arising from the speed and intricacy of polarization modulation.We introduce a high-speed modulation 3DSIM system,leveraging the polarizationmaintaining and modulation capabilities of a digital micromirror device(DMD)in conjunction with an electrooptic modulator.The DMD-3DSIM system yields a twofold enhancement in both lateral(133 nm)and axial(300 nm)resolution compared to wide-field imaging and can acquire a data set comprising 29 sections of 1024 pixels×1024 pixels,with 15 ms exposure time and 6.75 s per volume.The versatility of the DMD-3DSIM approach was exemplified through the imaging of various specimens,including fluorescent beads,nuclear pores,microtubules,actin filaments,and mitochondria within cells,as well as plant and animal tissues.Notably,polarized 3DSIM elucidated the orientation of actin filaments.Furthermore,the implementation of diverse deconvolution algorithms further enhances 3D resolution.The DMD-based 3DSIM system presents a rapid and reliable methodology for investigating biomedical phenomena,boasting capabilities encompassing 3D superresolution,fast temporal resolution,and polarization imaging.展开更多
The migration of healthcare professionals,including nurses,is a global phenomenon.It is driven by various factors,including the pursuit of better opportunities,living conditions,and professional development,as well as...The migration of healthcare professionals,including nurses,is a global phenomenon.It is driven by various factors,including the pursuit of better opportunities,living conditions,and professional development,as well as political instability or conflict in their home countries.The World Health Organization(WHO)has noted that high-income countries often rely on foreign-trained nurses to fill gaps in their healthcare systems[1].For instance,as of 2021,over 40%(52 million)of all nurses in the United States(US)were expatriates[2].In the United Kingdom(UK),the percentage of expatriate nurses was even higher,reaching approximately 18%in 2021[3].Owing to globalization and migration,healthcare providers must possess cultural competence to deliver improved care[4,5].Culturally responsive teaching(CRT)is rooted in the idea that culture plays a vital role in shaping people’s behaviors,beliefs,values,and communication styles[6].Furthermore,these cultural factors influence patients’perspectives on health,illness,healing,and their preferences for care and communication[7].By recognizing and embracing these cultural differences,nurses can provide more effective and compassionate care to their diverse patient population[8].展开更多
A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and locat...A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and located on the vacuum chamber wall at toroidal positionsφof 126.4°and 272.6°,respectively,while one set was established previously atφ=65.50.Each set of SXR arrays consists of three arrays viewing the plasma poloidally,and hence can be used separately to obtain SXR images via the tomographic method.The sawtooth precursor oscillations are measured by T-SXRI,and the corresponding images of perturbative SXR signals are successfully reconstructed at these three toroidal positions,hence providing measurement of the 3D structure of precursor oscillations.The observed 3D structure is consistent with the helical structure of the m/n=1/1 mode.The experimental observation confirms that the T-SXRI system is able to observe 3D structures in the J-TEXT plasma.展开更多
文摘The three-dimensional teaching mode is an integrated teaching mode,which integrates teaching design,teaching methods,teaching resources and student learning.In the English classroom,the three-dimensional teaching mode is used to make the English learning class full of vitality and to improve the effect of English classroom teaching.
文摘Purpose:Study the specific application effect of multi-dimensional and three-dimensional teaching in Geriatric Nursing teaching in the context of mass entrepreneurship and innovation.Methods:Respectively select 80 nursing undergraduates of 2015 and 80 nursing undergraduates of 2014 in our school as the research object of the experimental group and the control group.In terms of Geriatric Nursing teaching,nursing students in the control group adopt traditional classroom teaching methods to carry out,while students in the experimental group adopt multi-dimensional and three-dimensional teaching in the context of mass entrepreneurship and innovation.Then observe and compare the geriatric nursing knowledge scoring as well as theory and practice assessment results in the two groups taught with different methods.Results:It's obvious that the scoring of nursing students in the experimental group is higher than those in the control group in respect of geriatric nursing knowledge,and statistical significance exists in the between-group differences(P<0.05).The nursing students in the experimental group perform obviously better than those in the control group in terms of the results of theory,practice and comprehensive assessment as well as total score,and statistical significance exists in the between-group differences(P<0.05).Conclusion:Implementing Geriatric Nursing teaching for higher education nursing undergraduates with multi-dimensional and three-dimensional teaching in the context of mass entrepreneurship and innovation can remarkably improve nursing students'cognitive level in geriatric nursing as well as their mastery degree of theoretical,practical and comprehensive knowledge.Thus,the multi-dimensional and three-dimensional teaching mode in the context of mass entrepreneurship and innovation makes 80 nursing undergraduates of 2015 in our school direct beneficiaries,which could be popularized and applied in medical colleges.
文摘The paper discusses the application of three-dimensional textbook in English teaching. The three-dimensional textbook plays an incomparable function than the traditional textbook and thus has an extensive application in the college English education. It demonstrates the application through the usage of the three-dimensional textbook in the real teaching and shows that excessive usage of sound and pictures or drawings may distract the attention of students. It raises several suggestions at the end.
文摘The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model currently is mainly discussed. Meanwhile, the dynamic internal composition of the "three-dimensional teaching" is mainly introduced from its three stages and three principles, and also the three-dimensional teaching reform plan is supported and promoted based on two advantages.
基金Sponsored by 2022 “Tourism Industry Economic Teaching Innovation Team” of Taishan University。
文摘By analyzing the dilemma encountered in practical teaching of new media advertising course in the digital economy era, this paper explores the teaching path of new media advertising course based on “three-dimensional” practical teaching system, and believes that it is necessary to accurately determine talent training objectives, and construct the three dimensions of practical teaching, practical ability, and new media entrepreneurship and employment. Finally, the teaching countermeasures of practical teaching system based on three dimensions are put forward.
基金Supported by the National Natural Science Foundation of China (No.30901655)Shaanxi Provincial Key Research and Development Program (No.2018SF-230)
文摘AIM: To develop a novel three-dimensional(3D) electric ophthalmotrope to improve the ophthalmology teaching effectiveness and evaluate the teaching value. METHODS: A 3D electric ophthalmotrope was designed by simulating the movement of the ocular and the extraocular muscles according to Sherrington’s law. The model with joint bearing was to ensure the flexibility and centripetal rotation of the simulated ball and stepper motor as the driving device. A programmable processor was used to control the motion amplitude of the stepper motor. The size of hole was set at the back of the simulated shell to limit the amount of eye movement. Afterwards, using a 5-point Likert scale, 7 experts evaluated the 3D electric ophthalmotrope’s simulation ability and precision, compared with the traditional anatomical model. In addition, the teaching effectiveness of the 3D electric ophthalmotrope was evaluated at in-class quiz and final exam in a randomized controlled trial. RESULTS: The 3D electric ophthalmotrope could be operated easily to demonstrate the eye movements with motion of different ocular muscles. The experts agreed that the 3D electric ophthalmotrope was different from the traditional model and was easier for students to understand every extraocular muscles’ movement in each evaluation index(P<0.05). Moreover, the results of teaching effectiveness showed that the 3D electric ophthalmotrope were significantly greater than the traditional model both at in-class quiz(P<0.01) and final exam(P<0.05). CONCLUSION: This novel 3D electric ophthalmotrope is better than the traditional model, which can be to improve the ophthalmology teaching effectiveness for students to understand the extraocular muscles’ movement.
文摘Talent cultivation is the primary task of universities.Local general undergraduate colleges and universities should adhere to the basic guidelines of systematization,practicality and integration,continuously explore the concept of"studentcentered"talent cultivation,and build a threedimensional practical teaching system from three aspects:strengthening the planning and design of the three-dimensional practical teaching system;building an internal and external practical teaching platform;and improving the evaluation and guarantee system of practical teaching quality.The system of practical teaching quality evaluation and guarantee is improved.In order to improve the cultivation ability of applied talents in all aspects.
基金Sponsored by Beijing Natural Science Foundation (8202017)。
文摘Taking contents of Italian Renaissance gardens in the course Foreign Landscape Architecture History as an example,this paper introduces case teaching method and analyzes application of three-dimensional graphic analysis method in case teaching in detail,aiming at typical cases of Italian Renaissance gardens,namely,Villa Medici,Fiesole and Villa d’Este,Tivoli.Three-dimensional graphic analysis can help students form intuitive feeling of terrain and space,further understand the typical gardening techniques of foreign gardens,so as to improve the teaching effect of landscape architecture history course.
文摘It can be seen that it is of great practical signi? cance to evaluate practice teaching of tourism management specialty. Tourism management professional ability training objectives that is mainly refers to develop the tourism, ecology, tourism economics, tourism planning and development, management of travel agencies, tour guides, hotel management and tourism scenic spot management expertise, has complete professional ability has a skilled job skills in tourism industry to cultivate specialized personnel with high quality. The new local colleges and universities as an important role in higher education, entrepreneurship education in the process of exploring the important role of the gradually emerging and to explore the development of the entrepreneurship education in new local colleges and universities will help to cultivate pioneering talents extensively. This paper analyzes the issue from the essential perspective that will improve the general quality of the education.
基金Jiangxi Social Science Planning Project:Research on the Activation of Traditional Villages in Jiangxi Province from the Perspective of Cultural Conservation:A Case Study of Fuhe River Basin(Grant No.17BJ16).
文摘Based on the study of the application of three-dimensional laser scanning technology in ancient building surveying and mapping,this paper briefly describes the working principle and flow of three-dimensional laser scanning technology.Based on the practical application,this paper puts forward the discussion of related problems and matters needing attention.This has a certain reference significance for the study of new technology in surveying and mapping of ancient buildings.
文摘Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transformation.This transformation is still ongoing.In order to explain this phenomenon,we establish a three-dimension analysis framework of"ECONOMIC BASE-INFORMATION TECHNOLOGY-CULTURE".All kinds of logics involved in them are closely linked,thus influencing each other.At the same time,these aspects constantly affect the historical trajectory of the evolution.Based on the above analysis framework,the paper uses the historical approach to expound the evolution path on teaching methods in China since ancient times and divides it into four stages.Combined with the practical problems and interview results,we rethink the present information teaching methods.In the end,some suggestions are put forward in order to promote the further development of education-related fields.
基金Project supported by the National Natural Science Foundation of China (No. 12072337)。
文摘Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding through-thickness assumptions of the field variables are made,and the governing equations are two-dimensional,with the displacements and microrotations of the mid-plane as the unknowns.Once the deformation of the mid-plane is solved,a three-dimensional micropolar elastic field within the plate is generated,which is exact up to the second order except in the boundary region close to the plate edge.As an illustrative example,the bending of a clamped infinitely long plate caused by a uniformly distributed transverse force is analyzed and discussed in detail.
基金supported by the National Natural Science Foundation of China (No. 52275291)the Fundamental Research Funds for the Central Universitiesthe Program for Innovation Team of Shaanxi Province,China (No. 2023-CX-TD-17)
文摘Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor cells.This study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I collagen.It also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and migration.Finally,it compares two-dimensional(2D)and 3D cultures.For comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D model.Besides,the two models yielded significantly different cell morphologies.Finally,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D model.These results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture systems.The developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.
基金This work was supported by grants fromthe Sichuan Science and Technology Program(2023NSFSC1877).
文摘Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements.This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure.Here,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure.Furthermore,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical applications.The collective insights presented herein highlight the significance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.
基金Supported by The Key Medical Specialty Nurturing Program of Foshan During The 14th Five-Year Plan Period,No.FSPY145205The Medical Research Project of Foshan Health Bureau,No.20230814A010024+1 种基金The Guangzhou Science and Technology Plan Project,No.202102010251the Guangdong Science and Technology Program,No.2017ZC0222.
文摘BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.
基金supported by the National Natural Science Foundation of China,No.82171380(to CD)Jiangsu Students’Platform for Innovation and Entrepreneurship Training Program,No.202110304098Y(to DJ)。
文摘Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and the generation of new scars can make it very difficult for the impaired nervous system to restore its neural functionality.Traditional treatments can only alleviate secondary injuries but cannot fundamentally repair the spinal cord.Consequently,there is a critical need to develop new treatments to promote functional repair after spinal cord injury.Over recent years,there have been seve ral developments in the use of stem cell therapy for the treatment of spinal cord injury.Alongside significant developments in the field of tissue engineering,three-dimensional bioprinting technology has become a hot research topic due to its ability to accurately print complex structures.This led to the loading of three-dimensional bioprinting scaffolds which provided precise cell localization.These three-dimensional bioprinting scaffolds co uld repair damaged neural circuits and had the potential to repair the damaged spinal cord.In this review,we discuss the mechanisms underlying simple stem cell therapy,the application of different types of stem cells for the treatment of spinal cord injury,and the different manufa cturing methods for three-dimensional bioprinting scaffolds.In particular,we focus on the development of three-dimensional bioprinting scaffolds for the treatment of spinal cord injury.
文摘ObjectiveThis study aimed to explore the applications of three-dimensional (3D) technology, including virtual reality, augmented reality (AR), and 3D printing system, in the field of medicine, particularly in renal interventions for cancer treatment.MethodsA specialized software transforms 2D medical images into precise 3D digital models, facilitating improved anatomical understanding and surgical planning. Patient-specific 3D printed anatomical models are utilized for preoperative planning, intraoperative guidance, and surgical education. AR technology enables the overlay of digital perceptions onto real-world surgical environments.ResultsPatient-specific 3D printed anatomical models have multiple applications, such as preoperative planning, intraoperative guidance, trainee education, and patient counseling. Virtual reality involves substituting the real world with a computer-generated 3D environment, while AR overlays digitally created perceptions onto the existing reality. The advances in 3D modeling technology have sparked considerable interest in their application to partial nephrectomy in the realm of renal cancer. 3D printing, also known as additive manufacturing, constructs 3D objects based on computer-aided design or digital 3D models. Utilizing 3D-printed preoperative renal models provides benefits for surgical planning, offering a more reliable assessment of the tumor's relationship with vital anatomical structures and enabling better preparation for procedures. AR technology allows surgeons to visualize patient-specific renal anatomical structures and their spatial relationships with surrounding organs by projecting CT/MRI images onto a live laparoscopic video. Incorporating patient-specific 3D digital models into healthcare enhances best practice, resulting in improved patient care, increased patient satisfaction, and cost saving for the healthcare system.
基金supported by the National Key R&D Program of China (Award No.2022YFC3401100)the National Natural Science Foundation of China。
文摘In recent years,notable progress has been achieved in both the hardware and algorithms of structured illumination microscopy(SIM).Nevertheless,the advancement of three-dimensional structured illumination microscopy(3DSIM)has been impeded by challenges arising from the speed and intricacy of polarization modulation.We introduce a high-speed modulation 3DSIM system,leveraging the polarizationmaintaining and modulation capabilities of a digital micromirror device(DMD)in conjunction with an electrooptic modulator.The DMD-3DSIM system yields a twofold enhancement in both lateral(133 nm)and axial(300 nm)resolution compared to wide-field imaging and can acquire a data set comprising 29 sections of 1024 pixels×1024 pixels,with 15 ms exposure time and 6.75 s per volume.The versatility of the DMD-3DSIM approach was exemplified through the imaging of various specimens,including fluorescent beads,nuclear pores,microtubules,actin filaments,and mitochondria within cells,as well as plant and animal tissues.Notably,polarized 3DSIM elucidated the orientation of actin filaments.Furthermore,the implementation of diverse deconvolution algorithms further enhances 3D resolution.The DMD-based 3DSIM system presents a rapid and reliable methodology for investigating biomedical phenomena,boasting capabilities encompassing 3D superresolution,fast temporal resolution,and polarization imaging.
文摘The migration of healthcare professionals,including nurses,is a global phenomenon.It is driven by various factors,including the pursuit of better opportunities,living conditions,and professional development,as well as political instability or conflict in their home countries.The World Health Organization(WHO)has noted that high-income countries often rely on foreign-trained nurses to fill gaps in their healthcare systems[1].For instance,as of 2021,over 40%(52 million)of all nurses in the United States(US)were expatriates[2].In the United Kingdom(UK),the percentage of expatriate nurses was even higher,reaching approximately 18%in 2021[3].Owing to globalization and migration,healthcare providers must possess cultural competence to deliver improved care[4,5].Culturally responsive teaching(CRT)is rooted in the idea that culture plays a vital role in shaping people’s behaviors,beliefs,values,and communication styles[6].Furthermore,these cultural factors influence patients’perspectives on health,illness,healing,and their preferences for care and communication[7].By recognizing and embracing these cultural differences,nurses can provide more effective and compassionate care to their diverse patient population[8].
基金supported by the National Magnetic Confinement Fusion Energy R&D Program of China(Nos.2018YFE0309100 and 2019YFE03010004)National Natural Science Foundation of China(No.51821005)。
文摘A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and located on the vacuum chamber wall at toroidal positionsφof 126.4°and 272.6°,respectively,while one set was established previously atφ=65.50.Each set of SXR arrays consists of three arrays viewing the plasma poloidally,and hence can be used separately to obtain SXR images via the tomographic method.The sawtooth precursor oscillations are measured by T-SXRI,and the corresponding images of perturbative SXR signals are successfully reconstructed at these three toroidal positions,hence providing measurement of the 3D structure of precursor oscillations.The observed 3D structure is consistent with the helical structure of the m/n=1/1 mode.The experimental observation confirms that the T-SXRI system is able to observe 3D structures in the J-TEXT plasma.