COVID-19 is known for its magical infectivity,fast transmission and high death toll based on the large number of infected people.From the perspective of the clinical manifestation,autopsy examination and pathophysiolo...COVID-19 is known for its magical infectivity,fast transmission and high death toll based on the large number of infected people.From the perspective of the clinical manifestation,autopsy examination and pathophysiology,the essence of COVID-19 should be viewed as a sepsis induced by viral infection,and has the essential characteristics as sepsis induced by other pathogens.Therefore,in addition to etiological and supportive treatment,immunomodulatory therapy is also appropriate to severe COVID-19.Although there is still a lack of consensus on immunotherapy for sepsis so far,relatively rich experiences have been accumulated in the past decades,which will help us in the treatment of severe COVID-19.This article will elaborate immunotherapy of sepsis,though it may not be consistent.展开更多
文摘COVID-19 is known for its magical infectivity,fast transmission and high death toll based on the large number of infected people.From the perspective of the clinical manifestation,autopsy examination and pathophysiology,the essence of COVID-19 should be viewed as a sepsis induced by viral infection,and has the essential characteristics as sepsis induced by other pathogens.Therefore,in addition to etiological and supportive treatment,immunomodulatory therapy is also appropriate to severe COVID-19.Although there is still a lack of consensus on immunotherapy for sepsis so far,relatively rich experiences have been accumulated in the past decades,which will help us in the treatment of severe COVID-19.This article will elaborate immunotherapy of sepsis,though it may not be consistent.