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On Georg Lukacs’ Idea of Totality in His Period of Pre-Marxism
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作者 CHEN Gaohua 《Journal of Philosophy Study》 2019年第3期166-170,共5页
After the publication of History and Class Consciousness, the concept of totality became an important role through Georg Lukacs’ development of thought. Yet, this concept changed with his thinking. Indeed, totality a... After the publication of History and Class Consciousness, the concept of totality became an important role through Georg Lukacs’ development of thought. Yet, this concept changed with his thinking. Indeed, totality as an idea had emerged in his critique of capitalist culture in his pre-Marxism;we can claim that the concept of totality as Marxist dialectics originated in that period. Thus, it is necessary to interpret his idea of totality in pre-Marxism in order to understand wholly the concept of totality. 展开更多
关键词 Georg LUKACS EXTENSIVE totality INTENSIVE totality BELIEF in totality
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Kosik's Dialectics of Concrete Totality
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作者 Denko Skalovski 《Journal of Philosophy Study》 2015年第6期273-281,共9页
Setting out from the categories of totality and histori(ci)sm in Kosik's Dialectics of the Concrete, we look at the relationship between theory and praxis: empty, abstract totality versus concrete, reified and ali... Setting out from the categories of totality and histori(ci)sm in Kosik's Dialectics of the Concrete, we look at the relationship between theory and praxis: empty, abstract totality versus concrete, reified and alienated practice (Lukacs, Habermas, Honneth); a bad totality, in which the real polydimensional subject is replaced by the one-dimensional, mythologized, fetishized, and economistically reduced "subject" of consummation (Marcuse, Baudrillard). The dialectics of concrete totality implies a marxistic critique of the ethical and juristic universalism, in the context of the "positive" side of globalization and political unilateralism, as a concrete, militant, hegemonistic, post-colonial, and neo-imperial practice (Apel, Habermas, Chomsky, Zinoviev); globalization as totali(tari)zation, the "last man," the "end of history," and the "end" of dialectics in its neo-liberal, eschatological, empty ideological "realization" (Hegel, Marx, Fukuyama, Arendt); the totality of the (invariable) being as a pseudo-concrete and pseudo-dialectical ontologistic speculation (Heidegger): A "return" to a concrete history and a return of the "positive" dialectics as a critical awareness, mind, and method in the discourse "game" of human's cognitive, creative, and practical powers. The assumption of Kosik's humanism is a synchrony of nature and history in the "absolute" totality of human's concrete existence (Lukacs, Goldmann, Adorno, Sartre, Kosik). 展开更多
关键词 totality history nature DIALECTICS CONCRETE GLOBALIZATION MORAL REIFICATION
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Surgical site soft tissue thickness as a predictor of complications following arthroplasty
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作者 Kevin A Wu Faheem Pottayil +2 位作者 Crystal Jing Ankit Choudhury Albert T Anastasio 《World Journal of Methodology》 2025年第2期62-73,共12页
Appreciation of soft-tissue thickness(STT)at surgical sites is an increasingly recognized aspect of arthroplasty procedures as it may potentially impacting postoperative outcomes.Recent research has focused on the pre... Appreciation of soft-tissue thickness(STT)at surgical sites is an increasingly recognized aspect of arthroplasty procedures as it may potentially impacting postoperative outcomes.Recent research has focused on the predictive value of preoperative STT measurements for complications following various forms of arthroplasty,particularly infections,across procedures such as total knee,hip,shoulder,and ankle replacements.Several studies have indicated that increased STT is associated with a higher risk of complications,including infection and wound healing issues.The assessment of STT before surgery could play a crucial role in identifying patients at a higher risk of complications and may be instru-mental in guiding preoperative planning to optimize outcomes in arthroplasty procedures.Standardized measurement techniques and further research are essential to enhance the reliability and clinical utility of STT assessment for arthro-plasty surgery. 展开更多
关键词 Soft-tissue thickness ARTHROPLASTY Surgical complications Total knee arthroplasty Total hip arthroplasty Total shoulder arthroplasty Total ankle arthroplasty Preoperative assessment Wound healing Infection risk
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Chyle leak following root of mesentery dissection in pancreaticoduodenectomy with inferior infracolic superior mesenteric artery first approach
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作者 Prabir Maharjan Sujan Regmee +5 位作者 Spandan D Adhikari Rabin Pahari Roshan Ghimire Dhiresh K Maharjan Suman K Shrestha Prabin B Thapa 《World Journal of Clinical Cases》 SCIE 2025年第8期8-14,共7页
BACKGROUND The root of mesentery dissection is one of the critical maneuvers,especially in borderline resectable pancreatic head cancer.Intra-abdominal chyle leak(CL)including chylous ascites may ensue in up to 10%of ... BACKGROUND The root of mesentery dissection is one of the critical maneuvers,especially in borderline resectable pancreatic head cancer.Intra-abdominal chyle leak(CL)including chylous ascites may ensue in up to 10%of patients after pancreatic resections.Globally recognized superior mesenteric artery(SMA)first approaches are invariably performed.The mesenteric dissection through the inferior infracolic approach has been discussed in this study emphasizing its post-operative impact on CL which is the cornerstone of this study.AIM To assess incidence,risk factors,clinical impact of CL following root of mesentery dissection,and the different treatment modalities.METHODS This is a retrospective study incorporating the patients who underwent dissection of the root of mesentery with inferior infracolic SMA first approach pancreat-oduodenectomy for the ventral body and uncinate mass of pancreas in the Department of Gastrointestinal and General Surgery of Kathmandu Medical College and Teaching Hospital from January 1,2021 to February 28,2024.Intraop-erative findings and postoperative outcomes were analyzed.RESULTS In three years,ten patients underwent root of mesentery dissection with inferior infracolic SMA first approach pancreatoduodenectomy.The mean age was 67.6 years with a male-to-female ratio of 4:5.CL was seen in four patients.With virtue of CL,Clavien-Dindo grade Ⅱ or higher morbidity was observed in four patients.Two patients had a hospital stay of more than 20 days with the former having a delayed gastric emptying and the latter with long-term total parenteral nutrition requirement.The mean operative time was 330 minutes.Curative resection was achieved in 100%of the patients.The mean duration of the intensive care unit and hospital stay were 2.55±1.45 days and 15.7±5.32 days,respectively.CONCLUSION Root of mesentery dissection with lymphadenectomy and vascular resection correlated with occurrence of CL.After complete curative resection,these were managed with total parenteral nutrition without adversely impacting outcome. 展开更多
关键词 Chyle leak Chylous ascites Clavien-Dindo Pancreatoduodenectomy Root of mesentery dissection Superior mesenteric artery first approach Total parenteral nutrition Uncinate mass Vascular resection Ventral body mass
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Current and future perspectives in the management and treatment of colorectal cancer
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作者 Sigfredo E Romero-Zoghbi Evita Krumina +1 位作者 Fernando López-Campos Felipe Couñago 《World Journal of Clinical Oncology》 2025年第2期9-17,共9页
In this editorial,we reviewed the article by Fadlallah et al that was recently published in the World Journal of Clinical Oncology.The article provided a comprehensive and in-depth view of the management and treatment... In this editorial,we reviewed the article by Fadlallah et al that was recently published in the World Journal of Clinical Oncology.The article provided a comprehensive and in-depth view of the management and treatment of colorectal cancer(CRC),one of the leading causes of cancer-related morbidity and mortality worldwide.The article analyzed the therapeutic modalities and their sequencing,focusing on total neoadjuvant therapy for locally advanced rectal cancer.It highlighted the role of immunotherapy in tumors with high microsatellite instability or deficient mismatch repair,addressing recent advances that have improved prognosis and therapeutic response in localized and metastatic CRC.Innovations in surgical techniques,advanced radiotherapy,and systemic agents targeting specific mutational profiles are also discussed,reflecting on how they revolutionized clinical management.Circulating tumor DNA has emerged as a promising tool for detecting minimal residual disease,prognosis,and therapeutic monitoring,solidifying its role in precision oncology.This review emphasized the importance of technological and therapeutic advancements in improving clinical outcomes and personalizing CRC treatment. 展开更多
关键词 Colorectal cancer Metastatic colorectal cancer Total neoadjuvant therapy CHEMORADIOTHERAPY Colon surgery Rectal surgery CHEMOTHERAPY IMMUNOTHERAPY
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Realism: The Debate on Typicality, Totality, and Agency-A'Case Study of The Comedy by Chen Yan
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作者 CHEN Peihao 《Frontiers of Literary Studies in China-Selected Publications from Chinese Universities》 2023年第1期68-85,共18页
The Comedy is another of Chen Yan's masterpieces of realism after The Backstage Clan and The Protagonist.The difference is that the portrayal of He Jiabei in The Comedy echoes the theoretical idea of"typical ... The Comedy is another of Chen Yan's masterpieces of realism after The Backstage Clan and The Protagonist.The difference is that the portrayal of He Jiabei in The Comedy echoes the theoretical idea of"typical characters under typical circumstances."Through studies on Chen Yan's writing in a tensive theoretical space of"typicality,"we find that he has applied several important"typical"theories to his novels.He Jiabei,as a"typical character under typical circumstances"no longer embodies the ideal value as did Yi Qin'e in The Protagonist.The function of this character regardsthe communication between individuals and thetimes,phenomenon and essence."Typical characters under typical circumstances"is a theory generated from an analysis of realism inseparable from the"totality"of the times and history.The focus of The Comedy,a novel based on this theory,has also shifted from creating characters with distinct traits toexploring the historical essence of theera of"comedy." 展开更多
关键词 Chen Yan The Comedy REALISM totality AGENCY
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The Literary Writing of a"World of Totality"A Revisit to Builders of a New Life
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作者 HE Guimei 《Frontiers of Literary Studies in China-Selected Publications from Chinese Universities》 2022年第2期199-253,共55页
Builders of a New Life(Chuangyeshi)is a novel that takes a deep dive into the essence of historical materialism and dialectical materialism.The novel creates a literary form of political metanarrative and presents the... Builders of a New Life(Chuangyeshi)is a novel that takes a deep dive into the essence of historical materialism and dialectical materialism.The novel creates a literary form of political metanarrative and presents the literary narrative of the rural cooperative movement in China within the framework of socialist revolution,through a plot with the connotation of documentary political economy.At the literary narrative level,Builders of a New Life develops the narrative through the subjective perspectives of numerous characters,which pushes the development of the plot forward and bridges the text world with external reality.The result is the creation of a world of general literature unifying thought,emotion and action,along with the development of a distinctive epic narrative form. 展开更多
关键词 Builders of a New Life Liu Qing world of totality socialist realism
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Analysis of the causes of primary revision after unicompartmental knee arthroplasty: A case series 被引量:3
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作者 Jin-Long Zhao Xiao Jin +5 位作者 He-Tao Huang Wei-Yi Yang Jia-Hui Li Ming-Hui Luo Jun Liu Jian-Ke Pan 《World Journal of Clinical Cases》 SCIE 2024年第9期1560-1568,共9页
BACKGROUND Unicompartmental knee arthroplasty(UKA)has great advantages in the treatment of unicompartmental knee osteoarthritis,but its revision rate is higher than that of total knee arthroplasty.AIM To summarize and... BACKGROUND Unicompartmental knee arthroplasty(UKA)has great advantages in the treatment of unicompartmental knee osteoarthritis,but its revision rate is higher than that of total knee arthroplasty.AIM To summarize and analyse the causes of revision after UKA.METHODS This is a retrospective case series study in which the reasons for the first revision after UKA are summarized.We analysed the clinical symptoms,medical histories,laboratory test results,imaging examination results and treatment processes of the patients who underwent revision and summarized the reasons for primary revision after UKA.RESULTS A total of 13 patients,including 3 males and 10 females,underwent revision surgery after UKA.The average age of the included patients was 67.62 years.The prosthesis was used for 3 d to 72 months.The main reasons for revision after UKA were improper suturing of the surgical opening(1 patient),osteophytes(2 patients),intra-articular loose bodies(2 patients),tibial prosthesis loosening(2 patients),rheumatoid arthritis(1 patient),gasket dislocation(3 patients),anterior cruciate ligament injury(1 patient),and medial collateral ligament injury with residual bone cement(1 patient).CONCLUSION The causes of primary revision after UKA were gasket dislocation,osteophytes,intra-articular loose bodies and tibial prosthesis loosening.Avoidance of these factors may greatly reduce the rate of revision after UKA,improve patient satisfaction and reduce medical burden. 展开更多
关键词 Unicompartmental knee arthroplasty Total knee arthroplasty CAUSES REVISION Case series
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Rehabilitation care for pain in elderly knee replacement patients 被引量:3
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作者 Li Liu Qiao-Zhen Guan Li-Fang Wang 《World Journal of Clinical Cases》 SCIE 2024年第4期721-728,共8页
BACKGROUND Total knee arthroplasty(TKA)is recognized as the most effective surgical intervention for relieving pain and improving joint mobility and deformity in patients with knee osteoarthritis and other synovial di... BACKGROUND Total knee arthroplasty(TKA)is recognized as the most effective surgical intervention for relieving pain and improving joint mobility and deformity in patients with knee osteoarthritis and other synovial diseases.The application of accelerated postoperative rehabilitation(enhanced recovery after surgery)has demonstrated its efficacy in improving patient outcomes,and early postoperative joint function exercise has become a key prognostic factor in knee replacement.The unexpected appearance of limb pain and swelling hindered the patient’s tendency for early mobilization,leading in prolonged hospitalization,delayed functional recovery and negative psychological responses.A retrospective analysis was conducted on a cohort of 116 patients who under-went TKA at our hospital between July 2019 and July 2021.The patients were divided into two groups:A control group(n=58)receiving programmatic nur-sing,and an observed group(n=58)receiving programmed nursing combined with a collaborative nursing model.A pain management team consisting of attending physicians,head nurses,and responsible nurses was established.Outcome measures included visual analogue scale(VAS)scores,activities of daily living(ADL)scale scores,and functional scores.The ADL scores of patients in both groups exhibited a continuous increase.However,there was no statistically significant difference in the ADL scores between the two groups at 48 h and the 7th d post-surgery(P>0.05).Upon reexamination at the 3rd mo,the observation group demonstrated higher ADL scores compared to the control group(67.48±14.69 vs 59.40±16.06,P<0.05).The VAS scores of both groups significantly decreased,with no significant difference observed between the groups at each time point(P>0.05).The functional status of patients in both groups exhibited a gradual increase prior to intervention and at the 1st,2nd,and 3rd month following discharge(P<0.05).There was no statistically significant difference in knee joint function scores between the two groups at the 1st month after discharge(47.52 vs 45.81,P>0.05).However,the knee joint function scores of patients in the observation group were significantly higher than those in the control group at the 2nd(59.38 vs 53.19,P<0.05)and 3rd month(71.92 vs 64.34,P<0.05)following discharge.CONCLUSION The utilization of programmed pain nursing in conjunction with collaborative nursing for out-of-hospital care of TKA patients has demonstrated favorable outcomes,encompassing pain reduction,enhanced prognosis,and improved nursing quality for patients. 展开更多
关键词 Programmed pain nursing Collaborative nursing Total knee arthroplasty
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Meta-analysis of factors influencing anterior knee pain after total knee arthroplasty 被引量:2
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作者 Hui Feng Ming-Li Feng +2 位作者 Jing-Bo Cheng Xiang Zhang Hai-Cheng Tao 《World Journal of Orthopedics》 2024年第2期180-191,共12页
BACKGROUND Total knee arthroplasty(TKA)is a mature procedure recommended for correcting knee osteoarthritis deformity,relieving pain,and restoring normal biomechanics.Although TKA is a successful and cost-effective pr... BACKGROUND Total knee arthroplasty(TKA)is a mature procedure recommended for correcting knee osteoarthritis deformity,relieving pain,and restoring normal biomechanics.Although TKA is a successful and cost-effective procedure,patient dissatisfaction is as high as 50%.Knee pain after TKA is a significant cause of patient dissatisfaction;the most common location for residual pain is the anterior region.Between 4%and 40%of patients have anterior knee pain(AKP).AIM To investigate the effect of various TKA procedures on postoperative AKP.METHODS We searched PubMed,EMBASE,and Cochrane from January 2000 to September 2022.Randomized controlled trials with one intervention in the experimental group and no corresponding intervention(or other interventions)in the control group were collected.Two researchers independently read the title and abstract of the studies,preliminarily screened the articles,and read the full text in detail according to the selection criteria.Conflicts were resolved by consultation with a third researcher.And relevant data from the included studies were extracted and analyzed using Review Manager 5.4 software.RESULTS There were 25 randomized controlled trials;13 were comparative studies with or without patellar resurfacing.The meta-analysis showed no significant difference between the experimental and control groups(P=0.61).Six studies were comparative studies of circumpatellar denervation vs non-denervation,divided into three subgroups for meta-analysis.The two-subgroup meta-analysis showed no significant difference between the experimental and the control groups(P=0.31,P=0.50).One subgroup meta-analysis showed a significant difference between the experimental and control groups(P=0.001).Two studies compared fixed-bearing TKA and mobile-bearing TKA;the results meta-analysis showed no significant difference between the experimental and control groups(P=0.630).Two studies compared lateral retinacular release vs non-release;the meta-analysis showed a significant difference between the experimental and control groups(P=0.002);two other studies compared other factors.CONCLUSION Patellar resurfacing,mobile-bearing TKA,and fixed-bearing TKA do not reduce the incidence of AKP.Lateral retinacular release can reduce AKP;however,whether circumpatellar denervation can reduce AKP is controversial. 展开更多
关键词 Total knee arthroplasty Anterior knee pain Knee osteoarthritis Interventions META-ANALYSIS
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Which approach of total hip arthroplasty is the best efficacy and least complication? 被引量:1
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作者 Lertkong Nitiwarangkul Natthapong Hongku +3 位作者 Oraluck Pattanaprateep Sasivimol Rattanasiri Patarawan Woratanarat Ammarin Thakkinstian 《World Journal of Orthopedics》 2024年第1期73-93,共21页
BACKGROUND Total hip arthroplasty is as an effective intervention to relieve pain and improve hip function.Approaches of the hip have been exhaustively explored about pros and cons.The efficacy and the complications o... BACKGROUND Total hip arthroplasty is as an effective intervention to relieve pain and improve hip function.Approaches of the hip have been exhaustively explored about pros and cons.The efficacy and the complications of hip approaches remains inconclusive.This study conducted an umbrella review to systematically appraise previous meta-analysis(MAs)including conventional posterior approach(PA),and minimally invasive surgeries as the lateral approach(LA),direct anterior approach(DAA),2-incisions method,mini-lateral approach and the newest technique direct superior approach(DSA)or supercapsular percutaneouslyassisted total hip(SuperPath).AIM To compare the efficacy and complications of hip approaches that have been published in all MAs and randomized controlled trials(RCTs).METHODS MAs were identified from MEDLINE and Scopus from inception until 2023.RCTs were then updated from the latest MA to September 2023.This study included studies which compared hip approaches and reported at least one outcome such as Harris Hip Score(HHS),dislocation,intra-operative fracture,wound compliData were independently selected,extracted and assessed by two reviewers.Network MA and cluster rank and surface under the cumulative ranking curve(SUCRA)were estimated for treatment efficacy and safety.RESULTS Finally,twenty-eight MAs(40 RCTs),and 13 RCTs were retrieved.In total 47 RCTs were included for reanalysis.The results of corrected covered area showed high degree(13.80%).Among 47 RCTs,most of the studies were low risk of bias in part of random process and outcome reporting,while other domains were medium to high risk of bias.DAA significantly provided higher HHS at three months than PA[pooled unstandardized mean difference(USMD):3.49,95%confidence interval(CI):0.98,6.00 with SUCRA:85.9],followed by DSA/SuperPath(USMD:1.57,95%CI:-1.55,4.69 with SUCRA:57.6).All approaches had indifferent dislocation and intraoperative fracture rates.SUCRA comparing early functional outcome and composite complications(dislocation,intra-operative fracture,wound complication,and nerve injury)found DAA was the best approach followed by DSA/SuperPath.CONCLUSION DSA/SuperPath had better earlier functional outcome than PA,but still could not overcome the result of DAA.This technique might be the other preferred option with acceptable complications. 展开更多
关键词 Total hip arthroplasty Total hip replacement APPROACH Supercapsular percutaneously-assisted total hip Harris Hip Score Intra-operative fracture
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Machine learning identifies the risk of complications after laparoscopic radical gastrectomy for gastric cancer 被引量:1
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作者 Qing-Qi Hong Su Yan +18 位作者 Yong-Liang Zhao Lin Fan Li Yang Wen-Bin Zhang Hao Liu He-Xin Lin Jian Zhang Zhi-Jian Ye Xian Shen Li-Sheng Cai Guo-Wei Zhang Jia-Ming Zhu Gang Ji Jin-Ping Chen Wei Wang Zheng-Rong Li Jing-Tao Zhu Guo-Xin Li Jun You 《World Journal of Gastroenterology》 SCIE CAS 2024年第1期79-90,共12页
BACKGROUND Laparoscopic radical gastrectomy is widely used,and perioperative complications have become a highly concerned issue.AIM To develop a predictive model for complications in laparoscopic radical gastrectomy f... BACKGROUND Laparoscopic radical gastrectomy is widely used,and perioperative complications have become a highly concerned issue.AIM To develop a predictive model for complications in laparoscopic radical gastrectomy for gastric cancer to better predict the likelihood of complications in gastric cancer patients within 30 days after surgery,guide perioperative treatment strategies for gastric cancer patients,and prevent serious complications.METHODS In total,998 patients who underwent laparoscopic radical gastrectomy for gastric cancer at 16 Chinese medical centers were included in the training group for the complication model,and 398 patients were included in the validation group.The clinicopathological data and 30-d postoperative complications of gastric cancer patients were collected.Three machine learning methods,lasso regression,random forest,and artificial neural networks,were used to construct postoperative complication prediction models for laparoscopic distal gastrectomy and laparoscopic total gastrectomy,and their prediction efficacy and accuracy were evaluated.RESULTS The constructed complication model,particularly the random forest model,could better predict serious complications in gastric cancer patients undergoing laparoscopic radical gastrectomy.It exhibited stable performance in external validation and is worthy of further promotion in more centers.CONCLUSION Using the risk factors identified in multicenter datasets,highly sensitive risk prediction models for complications following laparoscopic radical gastrectomy were established.We hope to facilitate the diagnosis and treatment of preoperative and postoperative decision-making by using these models. 展开更多
关键词 Gastric cancer Laparoscopic radical gastrectomy Postoperative complications Laparoscopic total gastrectomy
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Geophysical prediction of organic matter abundance in source rocks based on geochemical analysis:A case study of southwestern Bozhong Sag,Bohai Sea,China 被引量:1
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作者 Xiang Wang Guang-Di Liu +5 位作者 Xiao-Lin Wang Jin-Feng Ma Zhen-Liang Wang Fei-Long Wang Ze-Zhang Song Chang-Yu Fan 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期31-53,共23页
The Bozhong Sag is the largest petroliferous sag in the Bohai Bay Basin,and the source rocks of Paleogene Dongying and Shahejie Formations were buried deeply.Most of the drillings were located at the structural high,a... The Bozhong Sag is the largest petroliferous sag in the Bohai Bay Basin,and the source rocks of Paleogene Dongying and Shahejie Formations were buried deeply.Most of the drillings were located at the structural high,and there were few wells that met good quality source rocks,so it is difficult to evaluate the source rocks in the study area precisely by geochemical analysis only.Based on the Rock-Eval pyrolysis,total organic carbon(TOC)testing,the organic matter(OM)abundance of Paleogene source rocks in the southwestern Bozhong Sag were evaluated,including the lower of second member of Dongying Formation(E_(3)d2L),the third member of Dongying Formation(E_(3)d_(3)),the first and second members of Shahejie Formation(E_(2)s_(1+2)),the third member of Shahejie Formation(E_(2)s_(3)).The results indicate that the E_(2)s_(1+2)and E_(2)s_(3)have better hydrocarbon generative potentials with the highest OM abundance,the E_(3)d_(3)are of the second good quality,and the E_(3)d2L have poor to fair hydrocarbon generative potential.Furthermore,the well logs were applied to predict TOC and residual hydrocarbon generation potential(S_(2))based on the sedimentary facies classification,usingΔlogR,generalizedΔlogR,logging multiple linear regression and BP neural network methods.The various methods were compared,and the BP neural network method have relatively better prediction accuracy.Based on the pre-stack simultaneous inversion(P-wave impedance,P-wave velocity and density inversion results)and the post-stack seismic attributes,the three-dimensional(3D)seismic prediction of TOC and S_(2)was carried out.The results show that the seismic near well prediction results of TOC and S_(2)based on seismic multi-attributes analysis correspond well with the results of well logging methods,and the plane prediction results are identical with the sedimentary facies map in the study area.The TOC and S_(2)values of E_(2)s_(1+2)and E_(2)s_(3)are higher than those in E_(3)d_(3)and E_(3)d_(2)L,basically consistent with the geochemical analysis results.This method makes up the deficiency of geochemical methods,establishing the connection between geophysical information and geochemical data,and it is helpful to the 3D quantitative prediction and the evaluation of high-quality source rocks in the areas where the drillings are limited. 展开更多
关键词 Total organic carbon(TOC) Residual hydrocarbon generation potential(S_(2)) Geophysical prediction Seismic attribute Bozhong Sag Bohai Bay Basin
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Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway 被引量:1
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作者 Zitian Gao Gaorui Wang +6 位作者 Yujie Chen Wuke Yuan Jun Cai Aiping Feng Jie Fang Qi Xu Xiaojun Wu 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期414-420,共7页
Parkinson’s disease(PD)is a common neurodegenerative disorder with no cure.Astragalus membranaceus is used in Chinese culture as a food supplement to boost immunity.The present study aimed to explore the neuroprotect... Parkinson’s disease(PD)is a common neurodegenerative disorder with no cure.Astragalus membranaceus is used in Chinese culture as a food supplement to boost immunity.The present study aimed to explore the neuroprotective effects of total flavonoids extracted from A.membranaceus(TFA)and their protective mechanisms.TFA offered neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)in the mouse model of Parkinsonism,by improving behavior performance in the gait analysis and pole test,and inhibiting the decline of tyrosine hydroxylase(TH)positive neurons and TH protein expression in substantia nigra of mice.TFA also prevented 1-methyl-4-phenylpyridinium(MPP+)induced neurotoxicity in SHSY5Y cells,by increasing GSH and GSH/GSSG ratio,and reducing reactive oxygen species.In addition,the neuroprotective effects of TFA were associated with its ability to restore MPTP/MPP+induced downregulation of SLC7A11 and glutathione peroxidase 4(GPX-4).In conclusion,we demonstrated that TFA exerted significant neuroprotection against MPTP/MPP+induced neurodegeneration by inhibiting ferroptosis through the regulation of SLC7A11/GPX-4 axis,suggesting the use of TFA as a possible food supplement in the prevention of PD. 展开更多
关键词 Parkinson’s disease Total fl avonoids of Astragalus membranaceus Ferroptosis SLC7A11
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Blood metal concentrations and cardiac structure and function in total joint arthroplasty patients 被引量:1
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作者 Peter C Brennan Stephanie M Peterson +6 位作者 Thomas J O'Byrne Mariana L Laporta Cody C Wyles Paul J Jannetto Garvan C Kane Maria Vassilaki Hilal Maradit Kremers 《World Journal of Orthopedics》 2024年第8期773-782,共10页
BACKGROUND There is concern regarding potential long-term cardiotoxicity with systemic distribution of metals in total joint arthroplasty(TJA)patients.AIM To determine the association of commonly used implant metals w... BACKGROUND There is concern regarding potential long-term cardiotoxicity with systemic distribution of metals in total joint arthroplasty(TJA)patients.AIM To determine the association of commonly used implant metals with echocardiographic measures in TJA patients.METHODS The study comprised 110 TJA patients who had a recent history of high chromium,cobalt or titanium concentrations.Patients underwent two-dimensional,three-dimensional,Doppler and speckle-strain transthoracic echocardiography and a blood draw to measure metal concentrations.Age and sex-adjusted linear and logistic regression models were used to examine the association of metal concentrations(exposure)with echocardiographic measures(outcome).RESULTS Higher cobalt concentrations were associated with increased left ventricular end-diastolic volume(estimate 5.09;95%CI:0.02-10.17)as well as left atrial and right ventricular dilation,particularly in men but no changes in cardiac function.Higher titanium concentrations were associated with a reduction in left ventricle global longitudinal strain(estimate 0.38;95%CI:0.70 to 0.06)and cardiac index(estimate 0.08;95%CI,-0.15 to-0.01).CONCLUSION Elevated cobalt and titanium concentrations may be associated with structural and functional cardiac changes in some patients.Longitudinal studies are warranted to better understand the systemic effects of metals in TJA patients. 展开更多
关键词 Total joint arthroplasty METAL-ON-METAL CARDIOTOXICITY Heart failure ECHOCARDIOGRAPHY COBALT
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Dislocation of primary total hip arthroplasty:Analysis of risk factors and preventive options 被引量:1
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作者 Dario Regis Mattia Cason Bruno Magnan 《World Journal of Orthopedics》 2024年第6期501-511,共11页
Total hip arthroplasty(THA)is one of the most successful elective operations in orthopedic surgery for improving pain and functional disability in patients with end-stage joint disease.However,dislocation continues to... Total hip arthroplasty(THA)is one of the most successful elective operations in orthopedic surgery for improving pain and functional disability in patients with end-stage joint disease.However,dislocation continues to be a troublesome complication after THA,as it is a leading cause of revision and is associated with substantial social,health,and economic costs.It is a relatively rare,usually early occurrence that depends on both the patients’characteristics and the surgical aspects.The most recent and important finding is the special attention to be given preoperatively to spinopelvic mobility,which is closely related to the incidence of dislocation.Consequently,clinical and radiographic assessment of the lumbar spine is mandatory to identify an altered pelvic tilt that could suggest a different positioning of the cup.Lumbar spinal fusion is currently considered a risk factor for dislocation and revision regardless of whether it is performed prior to or after THA.Surgical options for its treatment and prevention include the use of prostheses with large diameter of femoral head size,dual mobility constructs,constrained liners,and modular neck stems. 展开更多
关键词 DISLOCATION Total hip arthroplasty Revision surgery REVIEW Risk factors COMPLICATION
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Predictive value of bilirubin and serum γ-glutamyltranspeptidase levels in type-2 diabetes mellitus patients with acute coronary syndrome 被引量:1
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作者 Jie Chen Wan-Chao Zhang +4 位作者 Xiao-Qiang Tang Ruo-Han Yin Tao Wang Xiao-Yu Wei Chang-Jie Pan 《World Journal of Diabetes》 SCIE 2024年第1期34-42,共9页
BACKGROUND Cardiovascular disease is a major complication of diabetes mellitus(DM).Type-2 DM(T2DM)is associated with an increased risk of cardiovascular events and mortality,while serum biomarkers may facilitate the p... BACKGROUND Cardiovascular disease is a major complication of diabetes mellitus(DM).Type-2 DM(T2DM)is associated with an increased risk of cardiovascular events and mortality,while serum biomarkers may facilitate the prediction of these outcomes.Early differential diagnosis of T2DM complicated with acute coronary syndrome(ACS)plays an important role in controlling disease progression and improving safety.AIM To investigate the correlation of serum bilirubin andγ-glutamyltranspeptidase(γ-GGT)with major adverse cardiovascular events(MACEs)in T2DM patients with ACS.METHODS The clinical data of inpatients from January 2022 to December 2022 were analyzed retrospectively.According to different conditions,they were divided into the T2DM complicated with ACS group(T2DM+ACS,n=96),simple T2DM group(T2DM,n=85),and simple ACS group(ACS,n=90).The clinical data and laboratory indices were compared among the three groups,and the correlations of serum total bilirubin(TBIL)levels and serumγ-GGT levels with other indices were discussed.T2DM+ACS patients received a 90-day follow-up after discharge and were divided into event(n=15)and nonevent(n=81)groups according to the occurrence of MACEs;Univariate and multivariate analyses were further used to screen the independent influencing factors of MACEs in patients.RESULTS The T2DM+ACS group showed higherγ-GGT,total cholesterol,low-density lipoprotein cholesterol(LDL-C)and glycosylated hemoglobin(HbA1c)and lower TBIL and high-density lipoprotein cholesterol levels than the T2DM and ACS groups(P<0.05).Based on univariate analysis,the event and nonevent groups were significantly different in age(t=3.3612,P=0.0011),TBIL level(t=3.0742,P=0.0028),γ-GGT level(t=2.6887,P=0.0085),LDL-C level(t=2.0816,P=0.0401),HbA1c level(t=2.7862,P=0.0065)and left ventricular ejection fraction(LEVF)levels(t=3.2047,P=0.0018).Multivariate logistic regression analysis further identified that TBIL level and LEVF level were protective factor for MACEs,and age andγ-GGT level were risk factors(P<0.05).CONCLUSION Serum TBIL levels are decreased andγ-GGT levels are increased in T2DM+ACS patients,and the two indices are significantly negatively correlated.TBIL andγ-GGT are independent influencing factors for MACEs in such patients. 展开更多
关键词 Acute coronary syndrome Type-2 diabetes mellitus Total bilirubin Major adverse cardiovascular events
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Performance Assessment of a Real PV System Connected to a Low-Voltage Grid 被引量:1
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作者 Gaber Magdy Mostafa Metwally +1 位作者 Adel A.Elbaset Esam Zaki 《Energy Engineering》 EI 2024年第1期13-26,共14页
The generation of photovoltaic(PV)solar energy is increasing continuously because it is renewable,unlimited,and clean energy.In the past,generation systems depended on non-renewable sources such as oil,coal,and gas.Th... The generation of photovoltaic(PV)solar energy is increasing continuously because it is renewable,unlimited,and clean energy.In the past,generation systems depended on non-renewable sources such as oil,coal,and gas.Therefore,this paper assesses the performance of a 51 kW PV solar power plant connected to a low-voltage grid to feed an administrative building in the 6th of October City,Egypt.The performance analysis of the considered grid-connected PV system is carried out using power system simulator for Engineering(PSS/E)software.Where the PSS/E program,monitors and uses the power analyzer that displays the parameters and measures some parameters such as current,voltage,total power,power factor,frequency,and current and voltage harmonics,the used inverter from the type of grid inverter for the considered system.The results conclude that when the maximum solar radiation is reached,the maximum current can be obtained from the solar panels,thus obtaining the maximum power and power factor.Decreasing total voltage harmonic distortion,a current harmonic distortion within permissible limits using active harmonic distortion because this type is fast in processing up to 300 microseconds.The connection between solar stations and the national grid makes the system more efficient. 展开更多
关键词 Low-voltage grid photovoltaic(PV)system total harmonic distortion grid-connected PV system
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Research Progress and Prospects of Total Factor Productivity in the Construction Industry 被引量:1
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作者 Chen WANG Shijie YU +2 位作者 Chenhao LIANG Lidan CAI Xiaohong XIONG 《Asian Agricultural Research》 2024年第7期39-41,共3页
The high-quality development of the construction industry fundamentally stems from the significant improvement of total factor productivity.Therefore,it is of crucial significance for promoting the development of the ... The high-quality development of the construction industry fundamentally stems from the significant improvement of total factor productivity.Therefore,it is of crucial significance for promoting the development of the construction industry to a higher level by scientifically and accurately measuring the total factor productivity of the construction industry and deeply analyzing the influencing factors behind it.Based on a comprehensive consideration of research methods and influencing factors,this paper systematically reviews the existing relevant literature on total factor productivity in the construction industry,aiming to reveal the current research development trend in this field and point out potential problems.This effort aims to provide a solid theoretical foundation and valuable reference for further in-depth research,and jointly promote the continuous progress and development of total factor productivity research in the construction industry. 展开更多
关键词 Construction industry Total factor productivity Research progress Influence factor Theoretical basis
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Assessment of International GNSS Service Global Ionosphere Map products over China region based on measurements from the Crustal Movement Observation Network of China 被引量:1
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作者 Jin Hu HaiBing Ruan +2 位作者 FuQing Huang ShengYang Gu XianKang Dou 《Earth and Planetary Physics》 EI CAS CSCD 2024年第2期400-407,共8页
The global ionosphere maps(GIM)provided by the International GNSS Service(IGS)are extensively utilized for ionospheric morphology monitoring,scientific research,and practical application.Assessing the credibility of G... The global ionosphere maps(GIM)provided by the International GNSS Service(IGS)are extensively utilized for ionospheric morphology monitoring,scientific research,and practical application.Assessing the credibility of GIM products in data-sparse regions is of paramount importance.In this study,measurements from the Crustal Movement Observation Network of China(CMONOC)are leveraged to evaluate the suitability of IGS-GIM products over China region in 2013-2014.The indices of mean error(ME),root mean square error(RMSE),and normalized RMSE(NRMSE)are then utilized to quantify the accuracy of IGS-GIM products.Results revealed distinct local time and latitudinal dependencies in IGS-GIM errors,with substantially high errors at nighttime(NRMSE:39%)and above 40°latitude(NRMSE:49%).Seasonal differences also emerged,with larger equinoctial deviations(NRMSE:33.5%)compared with summer(20%).A preliminary analysis implied that the irregular assimilation of sparse IGS observations,compounded by China’s distinct geomagnetic topology,may manifest as error variations.These results suggest that modeling based solely on IGS-GIM observations engenders inadequate representations across China and that a thorough examination would proffer the necessary foundation for advancing regional total electron content(TEC)constructions. 展开更多
关键词 International GNSS Service(IGS)Global Ionosphere Maps(GIM) Crustal Movement Observation Network of China(CMONOC) total electron content(TEC) data assessment
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