A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 sho...A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 μg/mL, respectively.展开更多
基金supported by National Natural Science Foundation of China(No.30860345)National Basic Research Program of China(No.2007CB116306+1 种基金National Nonprofit Institute Research Grant of CATAS-ITBB(No.ITBBZD200744)the Natural Science Foundation of Hainan(Nos.80671,30608).
文摘A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 μg/mL, respectively.
