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Molecular mechanism and research progress of traditional Chinese medicine in the treatment of prostate cancer
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作者 Hai-Luo Wang Ruo-Ran Zhang +7 位作者 Hao Wang Peng Xu Jing-Kai Wang Bo Chen Hao Xu Deng Pan Yu-Yang Ma Kun Pang 《Traditional Medicine Research》 2025年第1期62-72,共11页
Prostate cancer(PCa)is one of the most common malignant tumors in the male genitourinary system,ranking second in incidence worldwide.Traditional Chinese medicine(TCM),as an important component of complementary and al... Prostate cancer(PCa)is one of the most common malignant tumors in the male genitourinary system,ranking second in incidence worldwide.Traditional Chinese medicine(TCM),as an important component of complementary and alternative medicine,shows unique advantages in cancer treatment.Chinese herbal medicine is usually composed of multiple ingredients and involves multiple signaling pathways,which showed function of inducing apoptosis of cancer cells,arresting the cell cycle,inhibiting invasion and metastasis,reducing drug resistance,and regulating immune function.Physical therapy is also an important treatment of TCM.Currently,Physical therapy such as acupuncture or Tai Chi and Qigong are gaining increased recognition in the management of PCa,particularly in addressing issues like urinary incontinence and bone metastasis-related pain.This article reviews the TCM treatment and therapy of PCa,in order to provide new research avenues and treatment options for the treatment of PCa with TCM and improve the quality of life of patients. 展开更多
关键词 traditional Chinese medicine prostate cancer Chinese herbal medicine physical therapy
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An interpretability model for syndrome differentiation of HBV-ACLF in traditional Chinese medicine using small-sample imbalanced data
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作者 ZHOU Zhan PENG Qinghua +3 位作者 XIAO Xiaoxia ZOU Beiji LIU Bin GUO Shuixia 《Digital Chinese Medicine》 CAS CSCD 2024年第2期137-147,共11页
Objective Clinical medical record data associated with hepatitis B-related acute-on-chronic liver failure(HBV-ACLF)generally have small sample sizes and a class imbalance.However,most machine learning models are desig... Objective Clinical medical record data associated with hepatitis B-related acute-on-chronic liver failure(HBV-ACLF)generally have small sample sizes and a class imbalance.However,most machine learning models are designed based on balanced data and lack interpretability.This study aimed to propose a traditional Chinese medicine(TCM)diagnostic model for HBV-ACLF based on the TCM syndrome differentiation and treatment theory,which is clinically interpretable and highly accurate.Methods We collected medical records from 261 patients diagnosed with HBV-ACLF,including three syndromes:Yang jaundice(214 cases),Yang-Yin jaundice(41 cases),and Yin jaundice(6 cases).To avoid overfitting of the machine learning model,we excluded the cases of Yin jaundice.After data standardization and cleaning,we obtained 255 relevant medical records of Yang jaundice and Yang-Yin jaundice.To address the class imbalance issue,we employed the oversampling method and five machine learning methods,including logistic regression(LR),support vector machine(SVM),decision tree(DT),random forest(RF),and extreme gradient boosting(XGBoost)to construct the syndrome diagnosis models.This study used precision,F1 score,the area under the receiver operating characteristic(ROC)curve(AUC),and accuracy as model evaluation metrics.The model with the best classification performance was selected to extract the diagnostic rule,and its clinical significance was thoroughly analyzed.Furthermore,we proposed a novel multiple-round stable rule extraction(MRSRE)method to obtain a stable rule set of features that can exhibit the model’s clinical interpretability.Results The precision of the five machine learning models built using oversampled balanced data exceeded 0.90.Among these models,the accuracy of RF classification of syndrome types was 0.92,and the mean F1 scores of the two categories of Yang jaundice and Yang-Yin jaundice were 0.93 and 0.94,respectively.Additionally,the AUC was 0.98.The extraction rules of the RF syndrome differentiation model based on the MRSRE method revealed that the common features of Yang jaundice and Yang-Yin jaundice were wiry pulse,yellowing of the urine,skin,and eyes,normal tongue body,healthy sublingual vessel,nausea,oil loathing,and poor appetite.The main features of Yang jaundice were a red tongue body and thickened sublingual vessels,whereas those of Yang-Yin jaundice were a dark tongue body,pale white tongue body,white tongue coating,lack of strength,slippery pulse,light red tongue body,slimy tongue coating,and abdominal distension.This is aligned with the classifications made by TCM experts based on TCM syndrome differentiation and treatment theory.Conclusion Our model can be utilized for differentiating HBV-ACLF syndromes,which has the potential to be applied to generate other clinically interpretable models with high accuracy on clinical data characterized by small sample sizes and a class imbalance. 展开更多
关键词 traditional Chinese medicine(TCM) Hepatitis B-related acute-on-chronic liver failure(HBV-ACLF) Imbalanced data Random forest(RF) interpretABILITY
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Interpretation of the Spatial Form of Chengdu Plain's Traditional Towns from the Vernacular Perspective 被引量:1
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作者 LIU Yongli SHEN Zhongwei 《Journal of Landscape Research》 2017年第1期15-18,共4页
In recent years,with the rapid development of urbanization in our country,academic circles have paid more attentions to and made fruitful achievements on the research of vernacular settlement. On this basis,this paper... In recent years,with the rapid development of urbanization in our country,academic circles have paid more attentions to and made fruitful achievements on the research of vernacular settlement. On this basis,this paper took Chengdu Plain's traditional town spatial morphology as the research object to interpret its spatial form through its composition elements and characteristics which are influenced by nature,history,culture and other factors. And then,it took Jiezi ancient town as an example to analyze the renewal of its spatial form so as to inherit the vernacular culture and promote the conservation of cultural heritage and sustainable development of traditional town in the course of constructing urban cities with Chinese characteristics. 展开更多
关键词 Vernacular settlement Chengdu Plain traditional town Spatial form
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American Patients’ Understanding of Traditional Chinese Medicine in the Late 19^(th) Century: An Interpretation of Letters from The Science of Oriental Medicine 被引量:2
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作者 Yu-Qing Qi Hong Zheng Shan Liu 《Chinese Medicine and Culture》 2021年第3期158-164,共7页
This study explores American patients’understanding of traditional Chinese medicine(TCM)in the late 19^(th) century by referring to letters from American patients recorded in The Science of Oriental Medicine,written ... This study explores American patients’understanding of traditional Chinese medicine(TCM)in the late 19^(th) century by referring to letters from American patients recorded in The Science of Oriental Medicine,written by Tan Fuyuan(谭富园),a Chinese medicine doctor working in the United States in the late Qing dynasty.Identifying a focus on significant effects,pulse diagnosis,herbal teas,dietary control,and long-term treatment,the results also discussed the differences between TCM and Western medicine in simple terms to show that the“ideological”spread of TCM was based on its curative effect.However,the“theoretical”spread of TCM requires more of intercultural exchanges. 展开更多
关键词 American patients Tan Fuyuan(谭富园) traditional Chinese medicine
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A Dialogue with the Ancient and Reflection on the Interpretation of History of Bianque and Traditional Chinese Medicine 被引量:1
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作者 Fu Youfeng(Beijing Hospital of Traditional Chinese Medicine Attached to Capital Medical University, Beijing 100010) 《工程科学(英文版)》 2007年第1期18-31,共14页
Based on the description of epidemic diseases in the chapter of “The Story of Bianque” in Records of Historian, the author has analyzed and explored the truthfulness of its background data and the possibility of the... Based on the description of epidemic diseases in the chapter of “The Story of Bianque” in Records of Historian, the author has analyzed and explored the truthfulness of its background data and the possibility of the plague spreading at that time from both macro and micro angles. The symptoms of plague including chills formation of some doctrines in Traditional Chinese Medicine (TCM) such as exopathic heat disease doctrine, internal injury of spleen and stomach doctrine and epidemic febrile disease doctrine. The course of exogenous phenomena, the author has explored the effect on the initial medical theory, primitive religion and culture due to the spreading of epidemic diseases from the angles of epidemiology, the theory of images and figures, originated from epidemic diseases was proposed. The author also put forward some opinions on the relationship between epidemic diseases spreading and traditional education of TCM, sustained development of TCM. 展开更多
关键词 Bianque HISTORY of traditionAL CHINESE MEDICINE PLAGUE FEBRILE disease acupuncture and moxibustion basic theory of traditionAL CHINESE MEDICINE
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Interpretation of Gastronomic Traditions within Tourism
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作者 Valerie Isabel Elss Giovanni Buono Johannes Treu 《Journal of Tourism and Hospitality Management》 2020年第2期60-67,共8页
This article presents a current EU project on the interpretation of Gastronomic European cultural heritage.Europe’s cultural heritage is highly diverse.This is by no means limited to museums,theatres,or castles;gastr... This article presents a current EU project on the interpretation of Gastronomic European cultural heritage.Europe’s cultural heritage is highly diverse.This is by no means limited to museums,theatres,or castles;gastronomic traditions are also part of Europe’s cultural heritage.As an essential part of the collective European memory,it is essential to preserve this diversity.From an economic perspective,the preservation of cultural heritage is a crucial task for the future.Within the EU,more than 300,000 people work in the cultural heritage sector;in addition,there are about 7.8 million jobs in the EU that correlate indirectly with cultural heritage(e.g.,tourism).How could gastronomic traditions be used to support a sustainable tourisms development? 展开更多
关键词 sustainable tourism cultural heritage methods of interpretation gastronomic traditions social identity
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Promotion of Standardization and Internalization of Traditional Chinese Medicine:Interpretation of Chapters in the 13^(th) Five-Year Special Project for Scientific Innovation of Traditional Chinese Medicine
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《中西医结合护理(中英文)》 2017年第6期1-6,共6页
Traditional Chinese medicine(TCM) contains profound scientific connotation and has great potential in guiding the future development of bioscience,thus becoming the Chinese Treasure of Ancient Science and the Key to O... Traditional Chinese medicine(TCM) contains profound scientific connotation and has great potential in guiding the future development of bioscience,thus becoming the Chinese Treasure of Ancient Science and the Key to Open the Treasury of Chinese Civilization. 13^(th) Five-Year Special Project for Scientific Innovation of Traditional Chinese Medicine has proposed to promote the standardization and internalization of TCM,including implementation of TCM standardized action,establishment of TCM standard system to complete system and adapt development requirements,establishment of a standard system for TCM that can complete system and meets the requirement of development to capture the advantages in international standardization competition,so as to seize the leadership and discourse power in the establishment of TCM international standardization;to promote the implementing great scientific TCM plan to accelerate the international registration of brand-name and high-quality TCM,expedite TCM service and products entering into international main markets of medicines and heath care,propel the scientific cooperation and application of TCM in various countries along One Belt and One Road(B & R),and create Chinese standards and brands,so as to promote the TCM moving towards the whole world. 展开更多
关键词 traditional Chinese medicine standardization INTERNATIONALIZATION
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Struggling Between Tradition and Modernity: A Feminist Interpretation of Yu Opera China Women
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作者 LIU Kang 《Sino-US English Teaching》 2019年第7期315-320,共6页
Yu Opera China Women (some translated it into Our Company)(2000) has been well received by audiences for its simple folk description, vivid characters, touching story lines, stunning stage backgrounds, and exquisite s... Yu Opera China Women (some translated it into Our Company)(2000) has been well received by audiences for its simple folk description, vivid characters, touching story lines, stunning stage backgrounds, and exquisite stage performances. The opera describes a story of Xiangxiang and Huanhuan, mother-in-law and daughter-in-law, two generations of women in the reform and opening up years in the 20th century in China. These Chinese women try to break the shackles of fate, with the strength to overcome hardships, work hard to gain wealth, and be brave to pursue true love, so it has a strong sense of feminism. However, rooted in the deep traditional Chinese culture, Xiangxiang and Huanhuan are always struggling between tradition and modernity and they make difficult choices along with the awakening of women’s consciousness. 展开更多
关键词 China WOMEN FEMINISM tradition STRUGGLE modernity
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The Ambiguous Boundary between Buildings and Environment: Exploring the Interpretation of Traditional Aesthetic in Contemporary Japanese Architecture
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作者 Perona Jiang 《Open Journal of Civil Engineering》 CAS 2022年第3期415-437,共23页
At present, nature is becoming more and more important in people’s mind. It is a very popular way to combine nature and humanity in architecture. Japanese architects have deep research and attainments in this respect... At present, nature is becoming more and more important in people’s mind. It is a very popular way to combine nature and humanity in architecture. Japanese architects have deep research and attainments in this respect, and combined with Japan’s unique humanistic care characteristics, can make the whole architectural style more lifelike. This paper will analyze the architectural style of Japan from several aspects and put forward its own views. 展开更多
关键词 Japanese Architecture Harmony between Humans and Nature traditional Aesthetics
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Interpretation and Application of Traditional Chinese Architectural Elements "Brick and Tile" in the Modem Interior Design Context
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作者 Hao ZHANG Xue WU 《International Journal of Technology Management》 2014年第4期122-124,共3页
Brick and tile were originally the building components for meeting a certain function, and have been widely applied to the field of the interior design today through designer' s unique understanding and constant desi... Brick and tile were originally the building components for meeting a certain function, and have been widely applied to the field of the interior design today through designer' s unique understanding and constant design thinking, so that they are developed into the symbolic signs with the characteristics of traditional Chinese culture. However, "function is converted to symbolic sign" as a model of thinking is a reflection and return of the traditional culture to the spirit of the times, and it carries forward the essence of the nation. 展开更多
关键词 Brick and Tile Function SIGN traditional Culture
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Five commonly used traditional Chinese medicine formulas in the treatment of ulcerative colitis:A network meta-analysis 被引量:2
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作者 Zhi-Hui Zhao Yi-Hang Dong +5 位作者 Xin-Qi Jiang Jing Wang Wan-Li Qin Zhang-Yi Liu Xiao-Qing Zhang Yu-Jie Wei 《World Journal of Clinical Cases》 SCIE 2024年第22期5067-5082,共16页
BACKGROUND Currently,traditional Chinese medicine(TCM)formulas are commonly being used as adjunctive therapy for ulcerative colitis in China.Network meta-analysis,a quantitative and comprehensive analytical method,can... BACKGROUND Currently,traditional Chinese medicine(TCM)formulas are commonly being used as adjunctive therapy for ulcerative colitis in China.Network meta-analysis,a quantitative and comprehensive analytical method,can systematically compare the effects of different adjunctive treatment options for ulcerative colitis,providing scientific evidence for clinical decision-making.AIM To evaluate the clinical efficacy and safety of commonly used TCM for the treatment of ulcerative colitis(UC)in clinical practice through a network metaanalysis.METHODS Clinical randomized controlled trials of these TCM formulas used for the adjuvant treatment of UC were searched from the establishment of the databases to July 1,2022.Studies that met the inclusion criteria were screened and evaluated for literature quality and risk of bias according to the Cochrane 5.1 standard.The methodological quality of the studies was assessed using ReviewManager(RevMan)5.4,and a funnel plot was constructed to test for publication bias.ADDIS 1.16 statistical software was used to perform statistical analysis of the treatment measures and derive the network relationship and ranking diagrams of the various intervention measures.RESULTS A total of 64 randomized controlled trials involving 5456 patients with UC were included in this study.The adjuvant treatment of UC using five TCM formulations was able to improve the clinical outcome of the patients.Adjuvant treatment with Baitouweng decoction(BTWT)showed a significant effect[mean difference=36.22,95%confidence interval(CI):7.63 to 65.76].For the reduction of tumor necrosis factor in patients with UC,adjunctive therapy with BTWT(mean difference=−9.55,95%CI:−17.89 to−1.41),Shenlingbaizhu powder[SLBZS;odds ratio(OR)=0.19,95%CI:0.08 to 0.39],and Shaoyao decoction(OR=−23.02,95%CI:−33.64 to−13.14)was effective.Shaoyao decoction was more effective than BTWT(OR=0.12,95%CI:0.03 to 0.39),SLBZS(OR=0.19,95%CI:0.08 to 0.39),and Xi Lei powder(OR=0.34,95%CI:0.13 to 0.81)in reducing tumor necrosis factor and the recurrence rate of UC.CONCLUSION TCM combined with mesalazine is more effective than mesalazine alone in the treatment of UC. 展开更多
关键词 Network meta-analysis traditional Chinese medicine Ulcerative colitis MESALAZINE TREATMENT
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Systems Theory-Driven Framework for AI Integration into the Holistic Material Basis Research of Traditional Chinese Medicine 被引量:1
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作者 Jingqi Zeng Xiaobin Jia 《Engineering》 SCIE EI CAS CSCD 2024年第9期28-50,共23页
This paper introduces a systems theory-driven framework to integration artificial intelligence(AI)into traditional Chinese medicine(TCM)research,enhancing the understanding of TCM’s holistic material basis while adhe... This paper introduces a systems theory-driven framework to integration artificial intelligence(AI)into traditional Chinese medicine(TCM)research,enhancing the understanding of TCM’s holistic material basis while adhering to evidence-based principles.Utilizing the System Function Decoding Model(SFDM),the research progresses through define,quantify,infer,and validate phases to systematically explore TCM’s material basis.It employs a dual analytical approach that combines top-down,systems theory-guided perspectives with bottom-up,elements-structure-function methodologies,provides comprehensive insights into TCM’s holistic material basis.Moreover,the research examines AI’s role in quantitative assessment and predictive analysis of TCM’s material components,proposing two specific AIdriven technical applications.This interdisciplinary effort underscores AI’s potential to enhance our understanding of TCM’s holistic material basis and establishes a foundation for future research at the intersection of traditional wisdom and modern technology. 展开更多
关键词 Artificial intelligence Systems theory traditional Chinese medicine Material basis BOTTOM-UP
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Knee osteoarthritis:A review of animal models and intervention of traditional Chinese medicine 被引量:1
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作者 Xuyu Song Ying Liu +5 位作者 Siyi Chen Lei Zhang Huijie Zhang Xianhui Shen Hang Du Rong Sun 《Animal Models and Experimental Medicine》 CAS CSCD 2024年第2期114-126,共13页
Background:Knee osteoarthritis(KOA)characterized by degeneration of knee cartilage and subsequent bone hyperplasia is a prevalent joint condition primarily affecting aging adults.The pathophysiology of KOA remains poo... Background:Knee osteoarthritis(KOA)characterized by degeneration of knee cartilage and subsequent bone hyperplasia is a prevalent joint condition primarily affecting aging adults.The pathophysiology of KOA remains poorly understood,as it involves complex mechanisms that result in the same outcome.Consequently,researchers are interested in studying KOA and require appropriate animal models for basic research.Chinese herbal compounds,which consist of multiple herbs with diverse pharmacological properties,possess characteristics such as multicomponent,multipathway,and multitarget effects.The potential benefits in the treatment of KOA continue to attract attention.Purpose:This study aims to provide a comprehensive overview of the advantages,limitations,and specific considerations in selecting different species and methods for KOA animal models.This will help researchers make informed decisions when choosing an animal model.Methods:Online academic databases(e.g.,PubMed,Google Scholar,Web of Science,and CNKI)were searched using the search terms“knee osteoarthritis,”“animal models,”“traditional Chinese medicine,”and their combinations,primarily including KOA studies published from 2010 to 2023.Results:Based on literature retrieval,this review provides a comprehensive overview of the methods of establishing KOA animal models;introduces the current status of advantages and disadvantages of various animal models,including mice,rats,rabbits,dogs,and sheep/goats;and presents the current status of methods used to establish KOA animal models.Conclusion:This study provides a review of the animal models used in recent KOA research,discusses the common modeling methods,and emphasizes the role of traditional Chinese medicine compounds in the treatment of KOA. 展开更多
关键词 animal models knee osteoarthritis system review traditional Chinese medicine
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Exploring the transformative impact of traditional Chinese medicine on depression:Insights from animal models 被引量:1
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作者 Yan Yang Yan-Kun Chen Meng-Zhou Xie 《World Journal of Psychiatry》 SCIE 2024年第5期607-623,共17页
Depression,a prevalent and complex mental health condition,presents a significant global health burden.Depression is one of the most frequent mental disorders;deaths from it account for 14.3%of people worldwide.In rec... Depression,a prevalent and complex mental health condition,presents a significant global health burden.Depression is one of the most frequent mental disorders;deaths from it account for 14.3%of people worldwide.In recent years,the integration of complementary and alternative medicine,including traditional Chinese medicine(TCM),has gained attention as a potential avenue for addressing depression.This comprehensive review critically assesses the efficacy of TCM interventions in alleviating depressive symptoms.An in-depth look at different research studies,clinical trials,and meta-analyses is used in this review to look into how TCM practices like herbal formulations,acupuncture,and mindbody practices work.The review looks at the quality of the evidence,the rigor of the methods,and any possible flaws in the current studies.This gives us an idea of where TCM stands right now in terms of treating depression.This comprehensive review aims to assess the efficacy of TCM interventions in alleviating depressive symptoms.In order to learn more about their possible healing effects,the study also looks into how different types of TCM work,such as herbal formulas,acupuncture,and mind-body practices. 展开更多
关键词 traditional Chinese medicine DEPRESSION EFFICACY Treatment Holistic approach
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Research progress on insomnia treated by traditional Chinese medicine and acupuncture based on microbial-gut-brain axis theory 被引量:1
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作者 Li-Min Pan Zhi-Bo Hong Rui-Qian Guan 《World Journal of Clinical Cases》 SCIE 2024年第18期3314-3320,共7页
Insomnia,as one of the emotional diseases,has been increasing in recent years,which has a great impact on people's life and work.Therefore,researchers are eager to find a more perfect treatment.The microbiome-gut-... Insomnia,as one of the emotional diseases,has been increasing in recent years,which has a great impact on people's life and work.Therefore,researchers are eager to find a more perfect treatment.The microbiome-gut-brain axis is a new theory that has gradually become popular abroad in recent years and has a profound impact in the field of insomnia.In recent years,traditional Chinese medicine(TCM)has played an increasingly important role in the treatment of insomnia,especially acupuncture and Chinese herbal medicine.It is the main method of TCM in the treatment of insomnia.This paper mainly reviews the combination degree of"microorganism-gut-brain axis"theory with TCM and acupuncture under the system of TCM.To explore the mechanism of TCM and acupuncture in the treatment of insomnia under the guidance of"microorganismgut-brain axis"theory,in order to provide a new idea for the diagnosis and treatment of insomnia. 展开更多
关键词 INSOMNIA Microorganism Intestine-brain axis traditional Chinese medicine Acupuncture and moxibustion
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Problem identification and revitalization strategies for the recovery and reconstruction of traditional villages in the Ms 6.8 Luding Earthquake 被引量:1
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作者 HUANG Chao QIU Jian +3 位作者 LIU Chun JIANG Rui ZHAO Chuanrong ZHANG Yi 《Journal of Mountain Science》 SCIE CSCD 2024年第2期361-379,共19页
Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarize... Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural heritage.Through a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction process.Traditional villages face the risk of declining or even loss of heritage value.In order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional villages.The research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process. 展开更多
关键词 Seismic hazard Decision making traditional village Cultural heritage protection Post-earthquake recovery and reconstruction Revitalization strategy
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Advances in the treatment of diabetic peripheral neuropathy by modulating gut microbiota with traditional Chinese medicine 被引量:1
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作者 Ye-Yao Li Rui-Qian Guan +2 位作者 Zhi-Bo Hong Yao-Lei Wang Li-Min Pan 《World Journal of Diabetes》 SCIE 2024年第8期1712-1716,共5页
Diabetic peripheral neuropathy(DPN)is one of the strongest risk factors for diabetic foot ulcers(neuropathic ulcerations)and the existing ulcers may further deteriorate due to the damage to sensory neurons.Moreover,th... Diabetic peripheral neuropathy(DPN)is one of the strongest risk factors for diabetic foot ulcers(neuropathic ulcerations)and the existing ulcers may further deteriorate due to the damage to sensory neurons.Moreover,the resulting numbness in the limbs causes difficulty in discovering these ulcerations in a short time.DPN is associated with gut microbiota dysbiosis.Traditional Chinese medicine(TCM)compounds such as Shenqi Dihuang Decoction,Huangkui Capsules and Qidi Tangshen Granules can reduce the clinical symptoms of diabetic nephropathy by modulating gut microbiota.The current review discusses whether TCM compounds can reduce the risk of DPN by improving gut microbiota. 展开更多
关键词 DIABETES Peripheral neuropathy traditional Chinese medicine Gut microbiota Diabetic foot ulcer TREATMENT
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Application of multidisciplinary team-based integrated traditional Chinese medicine and Western medicine in rotator cuff injury patients undergoing arthroscopic surgery 被引量:1
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作者 Di-Ping Cao Lei Yin +1 位作者 Yi-Fei Wang Bing-Li Liu 《World Journal of Clinical Cases》 SCIE 2024年第19期3767-3775,共9页
BACKGROUND Arthroscopic rotator cuff repair is a common surgical treatment for rotator cuff injuries(RCIs).Although this procedure has certain clinical advantages,it requires rehabilitation management interventions to... BACKGROUND Arthroscopic rotator cuff repair is a common surgical treatment for rotator cuff injuries(RCIs).Although this procedure has certain clinical advantages,it requires rehabilitation management interventions to ensure therapeutic efficacy.AIM To investigate the effect of integrated traditional Chinese medicine and Western medicine(TCM-WM)under the multidisciplinary team(MDT)model on the postoperative recovery of patients undergoing arthroscopic surgery for RCIs.METHODS This study enrolled 100 patients who underwent arthroscopic rotator cuff repair for RCIs at the Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine between June 2021 and May 2024.They were divided into a control group(n=48)that received routine rehabilitation treatment and an experimental group(n=52)that received TCM-WM under the MDT model(e.g.,acupuncture,TCM traumatology and orthopedics,and rehabilitation).The results of the Constant–Murley Shoulder Score(CMS),Visual Analogue Scale(VAS),Shoulder Pain and Disability Index(SPADI),muscular strength evaluation,and shoulder range of motion(ROM)assessments were analyzed.RESULTS After treatment,the experimental group showed significantly higher CMS scores in terms of pain,functional activity,shoulder joint mobility,and muscular strength than the baseline and those of the control group.The experimental group also exhibited significantly lower VAS and SPADI scores than the baseline and those of the control group.In addition,the experimental group showed significantly enhanced muscular strength(forward flexor and external and internal rotator muscles)and shoulder ROM(forward flexion,abduction,and lateral abduction)after treatment compared with the control group.CONCLUSION TCM-WM under the MDT model improved shoulder joint function,relieved postoperative pain,promoted postoperative functional recovery,and facilitated the recovery of muscular strength and shoulder ROM in patients with RCIs who underwent arthroscopic rotator cuff repair. 展开更多
关键词 Multidisciplinary team model Integrated traditional Chinese medicine and Western medicine Rotator cuff injury ARTHROSCOPY Arthroscopic surgery
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Intelligent geochemical interpretation of mass chromatograms:Based on convolution neural network
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作者 Kai-Ming Su Jun-Gang Lu +2 位作者 Jian Yu Zi-Xing Lu Shi-Jia Chen 《Petroleum Science》 SCIE EI CAS CSCD 2024年第2期752-764,共13页
Gas chromatography-mass spectrometry(GC-MS)is an extremely important analytical technique that is widely used in organic geochemistry.It is the only approach to capture biomarker features of organic matter and provide... Gas chromatography-mass spectrometry(GC-MS)is an extremely important analytical technique that is widely used in organic geochemistry.It is the only approach to capture biomarker features of organic matter and provides the key evidence for oil-source correlation and thermal maturity determination.However,the conventional way of processing and interpreting the mass chromatogram is both timeconsuming and labor-intensive,which increases the research cost and restrains extensive applications of this method.To overcome this limitation,a correlation model is developed based on the convolution neural network(CNN)to link the mass chromatogram and biomarker features of samples from the Triassic Yanchang Formation,Ordos Basin,China.In this way,the mass chromatogram can be automatically interpreted.This research first performs dimensionality reduction for 15 biomarker parameters via the factor analysis and then quantifies the biomarker features using two indexes(i.e.MI and PMI)that represent the organic matter thermal maturity and parent material type,respectively.Subsequently,training,interpretation,and validation are performed multiple times using different CNN models to optimize the model structure and hyper-parameter setting,with the mass chromatogram used as the input and the obtained MI and PMI values for supervision(label).The optimized model presents high accuracy in automatically interpreting the mass chromatogram,with R2values typically above 0.85 and0.80 for the thermal maturity and parent material interpretation results,respectively.The significance of this research is twofold:(i)developing an efficient technique for geochemical research;(ii)more importantly,demonstrating the potential of artificial intelligence in organic geochemistry and providing vital references for future related studies. 展开更多
关键词 Organic geochemistry BIOMARKER Mass chromatographic analysis Automated interpretation Convolution neural network Machine learning
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An improved deep dilated convolutional neural network for seismic facies interpretation
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作者 Na-Xia Yang Guo-Fa Li +2 位作者 Ting-Hui Li Dong-Feng Zhao Wei-Wei Gu 《Petroleum Science》 SCIE EI CAS CSCD 2024年第3期1569-1583,共15页
With the successful application and breakthrough of deep learning technology in image segmentation,there has been continuous development in the field of seismic facies interpretation using convolutional neural network... With the successful application and breakthrough of deep learning technology in image segmentation,there has been continuous development in the field of seismic facies interpretation using convolutional neural networks.These intelligent and automated methods significantly reduce manual labor,particularly in the laborious task of manually labeling seismic facies.However,the extensive demand for training data imposes limitations on their wider application.To overcome this challenge,we adopt the UNet architecture as the foundational network structure for seismic facies classification,which has demonstrated effective segmentation results even with small-sample training data.Additionally,we integrate spatial pyramid pooling and dilated convolution modules into the network architecture to enhance the perception of spatial information across a broader range.The seismic facies classification test on the public data from the F3 block verifies the superior performance of our proposed improved network structure in delineating seismic facies boundaries.Comparative analysis against the traditional UNet model reveals that our method achieves more accurate predictive classification results,as evidenced by various evaluation metrics for image segmentation.Obviously,the classification accuracy reaches an impressive 96%.Furthermore,the results of seismic facies classification in the seismic slice dimension provide further confirmation of the superior performance of our proposed method,which accurately defines the range of different seismic facies.This approach holds significant potential for analyzing geological patterns and extracting valuable depositional information. 展开更多
关键词 Seismic facies interpretation Dilated convolution Spatial pyramid pooling Internal feature maps Compound loss function
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