Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mi...Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;展开更多
BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street whe...BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street where the mosque is located,a name literally meaning Ox Street.The millennium mosque dates back to 996 and is the oldest and at 6,000 square meters,the largest of all the mosques in Beijing.The spacious prayer hall can easily accommodatel,000展开更多
文摘Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;
文摘BEIJING visitors or residents looking to spend down time in a tranquil setting can opt for the Niujie Mosque and its surrounds -a charming and often overlooked part of the capital. Niujie is the name of the street where the mosque is located,a name literally meaning Ox Street.The millennium mosque dates back to 996 and is the oldest and at 6,000 square meters,the largest of all the mosques in Beijing.The spacious prayer hall can easily accommodatel,000
