A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to d...A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to describe the viscosity function with a structural parameter λ which varies according to differ- ent kinetic orders of particle aggregation and segregation. The transient stress response is obtained by solving an instantaneous Maxwell model with an assumed shear modulus function G of the same form as the viscosity function η. Accuracy of the proposed model is verified experimentally with the results obtained for two oil (creosote)/water emulsions. The model that gives the best fit of experimental data appears to be the one with kinetic orders n = m = 2.展开更多
To decrease thermal stress during laser metal deposition shaping(LMDS)process,it is of great importance to learn the transient thermal stress distribution regularities.Based on the“element life and death”technique o...To decrease thermal stress during laser metal deposition shaping(LMDS)process,it is of great importance to learn the transient thermal stress distribution regularities.Based on the“element life and death”technique of finite element analy- sis(FEA),a three-dimensional multi-track and multi-layer numerical simulation model for LMDS is developed with ANSYS parametric design language(APDL)for the first time,in which long-edge parallel reciprocating scanning paths is introduced. Through the model,detailed simulations of thermal stress during whole metal cladding process are conducted,the generation and distribution regularities of thermal stress are also discussed in detail.Using the same process parameters,the simulation results show good agreement with the features of samples which fabricated by LMDS.展开更多
BACKGROUND: Restraint stress is a typical psychophysiological stressor. Simulating the early passion and difficulty in walking of patients after attack of stroke meets onset features.OBJECTIVE: To evaluate the effec...BACKGROUND: Restraint stress is a typical psychophysiological stressor. Simulating the early passion and difficulty in walking of patients after attack of stroke meets onset features.OBJECTIVE: To evaluate the effect of restraint stress on depression-like behaviors in rats after transient focal cerebral ischemic injury, and to investigate the feasibility for its being as modeling method of depression model after stroke.DESIGN: A randomized controlled animal experiment.SETTING: Department of Clinical Medicine, Faculty of Aerospace Medicine of the Fourth Military Medical University of Chinese PLA.MATERIALS: Forty-eight male Sprague-Dawley rats, weighing 240 - 270 g, provided by the Experimental Animal Center of the Fourth Military Medical University of Chinese PLA were used in the current study.METHODS: The experiments were carried out in the Faculty of Aerospace Medicine of the Fourth Military Medical University of Chinese PLA between August 2005 and August 2006. ①Experiment intervention: The rats were randomized into middle cerebral artery occlusion-reperfusion (MCAO) +stress group, simple MCAO group, sham-operation + stress group and simple sham-operation group, with 12 rats in each group.Rats in the first two groups were developed into cerebral ischemia/reperfusion models by suture-occluded method. Rats in the MCAO+stress group were modeled and restraint stress scheme was performed. At week 5 after modeling, the rats were placed in self-made restraining tubes, 2 hours/time, once a day, for 2 successive weeks. The common carotid artery, external and internal carotid arteries of rats in the latter two groups were exposed. The stress way of sham-operation+ stress group was the same as that of MCAO+ stress group. ②The neurological status grading and motor performance evaluation (screen test, rota-rod test and balance beam test) were conducted in rats with simple sham-operation group and MCAO group before, 1st and 28^th days after modeling. Depression-like behavior test was performed in the rats of each group by sucrose preference test and open field test at the end of the experiment.MAIN OUTCOME MEASURES: Changes of depression-like behaviors of rats in each group.RESULTS: Forty-eight rats were involved in the experiment. Two rats with meningeal irritation sign were excluded from simple MCAO group, and one rat in the MCAO+stress group died of some unclear causes during the experiments. The other 45 rats entered the stage of finial analysis. ① Depression-like behavior assessment results: The rats in the MCAO+ stress group had a significantly decreased preference for sucrose solution, crossing and rearing scores, and increased immobility duration after the 14-day restraint stress,compared with those in other three groups (all P〈0.05). ②The neurological status grading and motor performance evaluation: There were significant differences in the two indexes of rats in the simple MCAO group before, 1^st and 28^th days after modeling (P〈0.01), while there was no significant difference before and 28^th days after modeling (P〉0.05). There were no significant changes in sham-operation group at each time point (P〉0.05).CONCLUSION: After being exerted restraint stress, the rats with transient focal ischemic injury may show obvious depression-like behaviors. Therefore, restraint stress can be used as a novel animal modeling method for further studying biological mechanism in central nervous system of post-stroke depression animals.展开更多
The incorrect deduction of equations in the research works devoted to the studies of transient stress in cylindrically orthotropic tubes and done by Kardomateas (Journal of Applied Mechanics, 1989, 1990) leads to the ...The incorrect deduction of equations in the research works devoted to the studies of transient stress in cylindrically orthotropic tubes and done by Kardomateas (Journal of Applied Mechanics, 1989, 1990) leads to the wrong results. The errata (1991) correct the deduction error, but do not give the right numerical results. All errors are corrected, and the Mathematica is adopted to solve the large argument problem for Bessel function. A theoretical solution of the transient thermal stresses in tubes with uniform form is presented, and a numerical example is studied.展开更多
BACKGROUND Early prediction of transient ischemic attack (TIA) has important clinical value. To date, systematic studies on clinical, biochemical, and imaging indicators related to carotid atherosclerosis have been ca...BACKGROUND Early prediction of transient ischemic attack (TIA) has important clinical value. To date, systematic studies on clinical, biochemical, and imaging indicators related to carotid atherosclerosis have been carried out to predict the occurrence of TIA. However, their prediction accuracy is limited. AIM To explore the role of combining wall shear stress (WSS) with conventional predictive indicators in improving the accuracy of TIA prediction. METHODS A total of 250 patients with atherosclerosis who underwent carotid ultrasonography at Naval Military Medical University Affiliated Gongli Hospital were recruited. Plaque location, plaque properties, stenosis rate, peak systolic velocity, and end diastolic velocity were measured and recorded. The WSS distribution map of the proximal and distal ends of the plaque shoulder was drawn using the shear stress quantitative analysis software, and the average values of WSS were recorded. The laboratory indicators of the subjects were recorded. The patients were followed for 4 years. Patients with TIA were included in a TIA group and the remaining patients were included in a control group. The clinical data, laboratory indicators, and ultrasound characteristics of the two groups were analyzed. Survival curves were plotted by the Kaplan-Meier method. Receiver operating characteristic curves were established to evaluate the accuracy of potential indicators in predicting TIA. Logistic regression model was used to establish combined prediction, and the accuracy of combined predictive indicators for TIA was explored.RESULTS The intraclass correlation coefficients of the WSS between the proximal and distal ends of the plaque shoulder were 0.976 and 0.993, respectively, which indicated an excellent agreement. At the end of the follow-up, 30 patients suffered TIA (TIA group) and 204 patients did not (control group). Hypertension (P = 0.037), diabetes (P = 0.026), homocysteine (Hcy)(P = 0.022), fasting blood glucose (P = 0.034), plaque properties (P = 0.000), luminal stenosis rate (P = 0.000), and proximal end WSS (P = 0.000) were independent influencing factors for TIA during follow-up. The accuracy of each indicator for predicting TIA individually was not high (area under the curve [AUC]< 0.9). The accuracy of the combined indicator including WSS (AUC = 0.944) was significantly higher than that of the combined indicator without WSS (AUC = 0.856) in predicting TIA (z = 2.177, P = 0.030). The sensitivity and specificity of the combined indicator including WSS were 86.67% and 92.16%, respectively. CONCLUSION WSS at plaque surface combined with hypertension, diabetes, Hcy, blood glucose, plaque properties, and stenosis rate can significantly improve the accuracy of predicting TIA.展开更多
An analytical solution is obtained for transient torsional vibration of a finite hollow cylinder with initial axial stress. The cylinder is subjected to dynamic shearing stress at the internal surface and is fixed at ...An analytical solution is obtained for transient torsional vibration of a finite hollow cylinder with initial axial stress. The cylinder is subjected to dynamic shearing stress at the internal surface and is fixed at the external surface. The basic equations are presented and the solution is obtained by means of Fourier series expansion technique and the separation of variables method. The effects of the initial stress on the natural frequencies and transient torsional responses are presented and discussed.展开更多
Based on the situation of welding thermal conduction and thermo-elasto-platicity research, this paper explores some problems in this field. First, the boundary element method for nonlinear problems is improved by line...Based on the situation of welding thermal conduction and thermo-elasto-platicity research, this paper explores some problems in this field. First, the boundary element method for nonlinear problems is improved by linearization of nonlinear problems and used in welding thermal conduction analysis. Second, the thermo-elasto-plastic finite element method is used for the welding stress calculation, in which the phase transformation is considered by the 'equivalent linear expansion coefficient method'. The comparison of the calculated results with experimental data shows that the methods provided in this paper are available.展开更多
基于移相控制的双有源桥串联谐振变换器(dual-bridge series resonant converter,DBSRC)在传输功率的快速调控过程中,移相角将发生较大的阶跃变化,导致谐振腔出现大幅度长时间的振荡过程,不仅严重恶化了变换器的动态性能,电路元件也会...基于移相控制的双有源桥串联谐振变换器(dual-bridge series resonant converter,DBSRC)在传输功率的快速调控过程中,移相角将发生较大的阶跃变化,导致谐振腔出现大幅度长时间的振荡过程,不仅严重恶化了变换器的动态性能,电路元件也会面临严重的过电压和过电流风险。该文首先基于基波分析法推导DBSRC暂态过程的通用计算模型,分析暂态过程中的振荡特性,精确估算暂态过程中的谐振电压峰值、谐振电流峰值以及暂态过渡时间,评估暂态过程中的过电压与过电流程度。基于暂态过程计算模型,提出一种振荡的抑制方法,使变换器在一个开关周期后能够到达新的稳定状态,有效地避免了过电压与过电流的风险,并且大幅改善了闭环控制的动态特性。最后,通过仿真与实验结果验证理论分析和所提出的控制方法。展开更多
The transient finite element technique is applied, and a transient heat conduction model of wet brake friction disk is established. For obtaining the accurate heat flow density mathematic model and avoiding possibly i...The transient finite element technique is applied, and a transient heat conduction model of wet brake friction disk is established. For obtaining the accurate heat flow density mathematic model and avoiding possibly instable thermoelastic stress produced by the non uniform contact pressure of friction pair, a test method is applied to collect accurate contact pressure between the dual sheet steel and friction disk in the combining process. And then the heat-flow density and transient ther mo mechanical coupling simulation are analyzed. At the same time all possible boundary conditions are considered, such as the heat generation, heat conduction problem, relation between friction and contact, variation in load and heat change problem etc. The simulation results show that the me chanical model of thermo mechanical coupling can express well the dynamic characteristics of fric tion disk, and gives perfect reference for more study on thermoelastic distortion of brake friction pairs.展开更多
文摘A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to describe the viscosity function with a structural parameter λ which varies according to differ- ent kinetic orders of particle aggregation and segregation. The transient stress response is obtained by solving an instantaneous Maxwell model with an assumed shear modulus function G of the same form as the viscosity function η. Accuracy of the proposed model is verified experimentally with the results obtained for two oil (creosote)/water emulsions. The model that gives the best fit of experimental data appears to be the one with kinetic orders n = m = 2.
文摘To decrease thermal stress during laser metal deposition shaping(LMDS)process,it is of great importance to learn the transient thermal stress distribution regularities.Based on the“element life and death”technique of finite element analy- sis(FEA),a three-dimensional multi-track and multi-layer numerical simulation model for LMDS is developed with ANSYS parametric design language(APDL)for the first time,in which long-edge parallel reciprocating scanning paths is introduced. Through the model,detailed simulations of thermal stress during whole metal cladding process are conducted,the generation and distribution regularities of thermal stress are also discussed in detail.Using the same process parameters,the simulation results show good agreement with the features of samples which fabricated by LMDS.
文摘BACKGROUND: Restraint stress is a typical psychophysiological stressor. Simulating the early passion and difficulty in walking of patients after attack of stroke meets onset features.OBJECTIVE: To evaluate the effect of restraint stress on depression-like behaviors in rats after transient focal cerebral ischemic injury, and to investigate the feasibility for its being as modeling method of depression model after stroke.DESIGN: A randomized controlled animal experiment.SETTING: Department of Clinical Medicine, Faculty of Aerospace Medicine of the Fourth Military Medical University of Chinese PLA.MATERIALS: Forty-eight male Sprague-Dawley rats, weighing 240 - 270 g, provided by the Experimental Animal Center of the Fourth Military Medical University of Chinese PLA were used in the current study.METHODS: The experiments were carried out in the Faculty of Aerospace Medicine of the Fourth Military Medical University of Chinese PLA between August 2005 and August 2006. ①Experiment intervention: The rats were randomized into middle cerebral artery occlusion-reperfusion (MCAO) +stress group, simple MCAO group, sham-operation + stress group and simple sham-operation group, with 12 rats in each group.Rats in the first two groups were developed into cerebral ischemia/reperfusion models by suture-occluded method. Rats in the MCAO+stress group were modeled and restraint stress scheme was performed. At week 5 after modeling, the rats were placed in self-made restraining tubes, 2 hours/time, once a day, for 2 successive weeks. The common carotid artery, external and internal carotid arteries of rats in the latter two groups were exposed. The stress way of sham-operation+ stress group was the same as that of MCAO+ stress group. ②The neurological status grading and motor performance evaluation (screen test, rota-rod test and balance beam test) were conducted in rats with simple sham-operation group and MCAO group before, 1st and 28^th days after modeling. Depression-like behavior test was performed in the rats of each group by sucrose preference test and open field test at the end of the experiment.MAIN OUTCOME MEASURES: Changes of depression-like behaviors of rats in each group.RESULTS: Forty-eight rats were involved in the experiment. Two rats with meningeal irritation sign were excluded from simple MCAO group, and one rat in the MCAO+stress group died of some unclear causes during the experiments. The other 45 rats entered the stage of finial analysis. ① Depression-like behavior assessment results: The rats in the MCAO+ stress group had a significantly decreased preference for sucrose solution, crossing and rearing scores, and increased immobility duration after the 14-day restraint stress,compared with those in other three groups (all P〈0.05). ②The neurological status grading and motor performance evaluation: There were significant differences in the two indexes of rats in the simple MCAO group before, 1^st and 28^th days after modeling (P〈0.01), while there was no significant difference before and 28^th days after modeling (P〉0.05). There were no significant changes in sham-operation group at each time point (P〉0.05).CONCLUSION: After being exerted restraint stress, the rats with transient focal ischemic injury may show obvious depression-like behaviors. Therefore, restraint stress can be used as a novel animal modeling method for further studying biological mechanism in central nervous system of post-stroke depression animals.
文摘The incorrect deduction of equations in the research works devoted to the studies of transient stress in cylindrically orthotropic tubes and done by Kardomateas (Journal of Applied Mechanics, 1989, 1990) leads to the wrong results. The errata (1991) correct the deduction error, but do not give the right numerical results. All errors are corrected, and the Mathematica is adopted to solve the large argument problem for Bessel function. A theoretical solution of the transient thermal stresses in tubes with uniform form is presented, and a numerical example is studied.
基金Supported by Shanghai Health and Family Planning Commission,No.201440051Shanghai Pudong New Area Health and Family Planning Commission,No.PW2016A-19
文摘BACKGROUND Early prediction of transient ischemic attack (TIA) has important clinical value. To date, systematic studies on clinical, biochemical, and imaging indicators related to carotid atherosclerosis have been carried out to predict the occurrence of TIA. However, their prediction accuracy is limited. AIM To explore the role of combining wall shear stress (WSS) with conventional predictive indicators in improving the accuracy of TIA prediction. METHODS A total of 250 patients with atherosclerosis who underwent carotid ultrasonography at Naval Military Medical University Affiliated Gongli Hospital were recruited. Plaque location, plaque properties, stenosis rate, peak systolic velocity, and end diastolic velocity were measured and recorded. The WSS distribution map of the proximal and distal ends of the plaque shoulder was drawn using the shear stress quantitative analysis software, and the average values of WSS were recorded. The laboratory indicators of the subjects were recorded. The patients were followed for 4 years. Patients with TIA were included in a TIA group and the remaining patients were included in a control group. The clinical data, laboratory indicators, and ultrasound characteristics of the two groups were analyzed. Survival curves were plotted by the Kaplan-Meier method. Receiver operating characteristic curves were established to evaluate the accuracy of potential indicators in predicting TIA. Logistic regression model was used to establish combined prediction, and the accuracy of combined predictive indicators for TIA was explored.RESULTS The intraclass correlation coefficients of the WSS between the proximal and distal ends of the plaque shoulder were 0.976 and 0.993, respectively, which indicated an excellent agreement. At the end of the follow-up, 30 patients suffered TIA (TIA group) and 204 patients did not (control group). Hypertension (P = 0.037), diabetes (P = 0.026), homocysteine (Hcy)(P = 0.022), fasting blood glucose (P = 0.034), plaque properties (P = 0.000), luminal stenosis rate (P = 0.000), and proximal end WSS (P = 0.000) were independent influencing factors for TIA during follow-up. The accuracy of each indicator for predicting TIA individually was not high (area under the curve [AUC]< 0.9). The accuracy of the combined indicator including WSS (AUC = 0.944) was significantly higher than that of the combined indicator without WSS (AUC = 0.856) in predicting TIA (z = 2.177, P = 0.030). The sensitivity and specificity of the combined indicator including WSS were 86.67% and 92.16%, respectively. CONCLUSION WSS at plaque surface combined with hypertension, diabetes, Hcy, blood glucose, plaque properties, and stenosis rate can significantly improve the accuracy of predicting TIA.
基金supported by the National Natural Science Foundation of China(Nos.10872179 and 10725210)the Zhejiang Provincial Natural Science Foundation of China(No.Y7080298) and the Zijin Plan of Zhejiang University.
文摘An analytical solution is obtained for transient torsional vibration of a finite hollow cylinder with initial axial stress. The cylinder is subjected to dynamic shearing stress at the internal surface and is fixed at the external surface. The basic equations are presented and the solution is obtained by means of Fourier series expansion technique and the separation of variables method. The effects of the initial stress on the natural frequencies and transient torsional responses are presented and discussed.
文摘Based on the situation of welding thermal conduction and thermo-elasto-platicity research, this paper explores some problems in this field. First, the boundary element method for nonlinear problems is improved by linearization of nonlinear problems and used in welding thermal conduction analysis. Second, the thermo-elasto-plastic finite element method is used for the welding stress calculation, in which the phase transformation is considered by the 'equivalent linear expansion coefficient method'. The comparison of the calculated results with experimental data shows that the methods provided in this paper are available.
文摘基于移相控制的双有源桥串联谐振变换器(dual-bridge series resonant converter,DBSRC)在传输功率的快速调控过程中,移相角将发生较大的阶跃变化,导致谐振腔出现大幅度长时间的振荡过程,不仅严重恶化了变换器的动态性能,电路元件也会面临严重的过电压和过电流风险。该文首先基于基波分析法推导DBSRC暂态过程的通用计算模型,分析暂态过程中的振荡特性,精确估算暂态过程中的谐振电压峰值、谐振电流峰值以及暂态过渡时间,评估暂态过程中的过电压与过电流程度。基于暂态过程计算模型,提出一种振荡的抑制方法,使变换器在一个开关周期后能够到达新的稳定状态,有效地避免了过电压与过电流的风险,并且大幅改善了闭环控制的动态特性。最后,通过仿真与实验结果验证理论分析和所提出的控制方法。
基金Supported by the National Basic Research Program of China("973"Program)(613002)
文摘The transient finite element technique is applied, and a transient heat conduction model of wet brake friction disk is established. For obtaining the accurate heat flow density mathematic model and avoiding possibly instable thermoelastic stress produced by the non uniform contact pressure of friction pair, a test method is applied to collect accurate contact pressure between the dual sheet steel and friction disk in the combining process. And then the heat-flow density and transient ther mo mechanical coupling simulation are analyzed. At the same time all possible boundary conditions are considered, such as the heat generation, heat conduction problem, relation between friction and contact, variation in load and heat change problem etc. The simulation results show that the me chanical model of thermo mechanical coupling can express well the dynamic characteristics of fric tion disk, and gives perfect reference for more study on thermoelastic distortion of brake friction pairs.