Objective: To observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD). Methods: Eighty-three patients of VD were randomized on ratio of 2 : 1 into two groups, the 54 patients in the tr...Objective: To observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD). Methods: Eighty-three patients of VD were randomized on ratio of 2 : 1 into two groups, the 54 patients in the treated group were treated with YTC orally administered, 3 times a展开更多
BACKGROUND Crohn’s disease(CD)can affect the entire gastrointestinal tract.Proximal small bowel(SB)lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries.The assessment...BACKGROUND Crohn’s disease(CD)can affect the entire gastrointestinal tract.Proximal small bowel(SB)lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries.The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prognosis with potential therapeutic implications.Because of the weak correlation that exists between symptoms and endoscopic disease activity,the“treat-to-target”paradigm has been developed,and the associated treatment goal is to achieve and maintain deep remission,encompassing both clinical and endoscopic remission.Small bowel capsule endoscopy(SBCE)allows to visualize the mucosal surface of the entire SB.At that time,there is no recommendation regarding the use of SBCE during follow-up.AIM To investigate the impact of SBCE in a treat-to-target strategy in patients with CD.METHODS An electronic literature search was conducted in PubMed and Cochrane library using the following search terms:“capsule endoscopy”,in combination with“Crohn’s disease”and“treat-to-target”or synonyms.Two authors independently reviewed titles and abstracts identified by the search strategy after duplicates were removed.Following the initial screening of abstracts,all articles containing information about SBCE in the context of treat-to-target strategy in patients with CD were included.Full-text articles were retrieved,reference lists were screened manually to identify additional studies.RESULTS Forty-seven articles were included in this review.Two indexes are currently used to quantify disease activity using SBCE,and there is good correlation between them.SBCE was shown to be useful for disease reclassification in patients who are suspected of having or who are diagnosed with CD,with a significant incremental diagnostic yield compared to other diagnostic modalities.Nine studies also demonstrated that the mucosal healing can be evaluated by SBCE to monitor the effect of medical treatment in patients with CD.This review also demonstrated that SBCE can detect post-operative recurrence to a similar extent as ileocolonoscopy,and proximal SB lesions that are beyond the reach of the colonoscope in over half of the patients.CONCLUSION SBCE could be incorporated in the treat-to-target algorithm for patients with CD.Randomized controlled trials are required to confirm its usefulness and reliability in this indication.展开更多
Capsule endoscopy(CE) has proved to be an important non-invasive tool for diagnosis and monitoring Crohn's disease patients.It has the advantage of excellent visualization of digestive tract mucosa,a good tolerabi...Capsule endoscopy(CE) has proved to be an important non-invasive tool for diagnosis and monitoring Crohn's disease patients.It has the advantage of excellent visualization of digestive tract mucosa,a good tolerability and safety in well-selected patients.The risk of retention can be diminished by good selection of patients using imaging techniques and by the use of patency capsule.The aim of a capsule examination is not only an early diagnosis but also a very good stratification of prognosis,thus directing the treatment strategy for either a step up or top-down approach and also permitting the optimization of the treatment depending on the findings.When symptoms and biomarkers point to a change in the disease's activity we can either adjust the treatment directly as recommended in CALM study or choose in selected patients to visualize the digestive mucosa through a CE and take a decision afterwards.The appearance of the new capsule from Medtronicthe Pillcam Crohn's might be an important step forward in diagnosis,evaluating disease extent,the severity of the disease,prognosis,management in a treat to target approach,with treatment modifications according to the data from CE examination.Serial examinations in the same patient can be compared and a more objective evaluation of the lesions modification from one exam to another can be performed.We present the latest developments and current status and evidence that in selected patients capsule can be a tool in a treat to target approach.展开更多
Objective To observe the clinical effect and efficacy of Xiaozhi Capsule (XZC) ,a Chinese medicine preparation for tonifying Gan-Shen,invigorating Pi to dissipate dampness (TGSIPDD) on total cholesterol (TC) ,triglyce...Objective To observe the clinical effect and efficacy of Xiaozhi Capsule (XZC) ,a Chinese medicine preparation for tonifying Gan-Shen,invigorating Pi to dissipate dampness (TGSIPDD) on total cholesterol (TC) ,triglyceride (TG) ,high-density lipoprotein cholesterol (HDLC) ,low-density lipoprotein cholesterol (LDL-C) 。展开更多
There were 120 cases of mammary gland hyperplasia which were treated by using Chinese herbal medicine--Ru Zeng Nin capsule and obtained satisfied effect. It was proved benign disease by surgen hand check and puncture ...There were 120 cases of mammary gland hyperplasia which were treated by using Chinese herbal medicine--Ru Zeng Nin capsule and obtained satisfied effect. It was proved benign disease by surgen hand check and puncture cytology, then divided them into two groups randomly. One group was Ru Zeng Nin capsule, another one was comparing. It was observed the condition about pain? tenderness? swelling piece after taking capsule half a year. The results showed that effective rate was 97 8%, cure rate was 80%. From this, we Rnow that Ru Zeng Nin capsule has better treatment effect to treast pain? mammary gland hypprplasia and fiber hyperplasia symptom. This capsule has safe and taking eary characteristic, so it’s easy to spread and opply in the clinical.展开更多
文摘Objective: To observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD). Methods: Eighty-three patients of VD were randomized on ratio of 2 : 1 into two groups, the 54 patients in the treated group were treated with YTC orally administered, 3 times a
文摘BACKGROUND Crohn’s disease(CD)can affect the entire gastrointestinal tract.Proximal small bowel(SB)lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries.The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prognosis with potential therapeutic implications.Because of the weak correlation that exists between symptoms and endoscopic disease activity,the“treat-to-target”paradigm has been developed,and the associated treatment goal is to achieve and maintain deep remission,encompassing both clinical and endoscopic remission.Small bowel capsule endoscopy(SBCE)allows to visualize the mucosal surface of the entire SB.At that time,there is no recommendation regarding the use of SBCE during follow-up.AIM To investigate the impact of SBCE in a treat-to-target strategy in patients with CD.METHODS An electronic literature search was conducted in PubMed and Cochrane library using the following search terms:“capsule endoscopy”,in combination with“Crohn’s disease”and“treat-to-target”or synonyms.Two authors independently reviewed titles and abstracts identified by the search strategy after duplicates were removed.Following the initial screening of abstracts,all articles containing information about SBCE in the context of treat-to-target strategy in patients with CD were included.Full-text articles were retrieved,reference lists were screened manually to identify additional studies.RESULTS Forty-seven articles were included in this review.Two indexes are currently used to quantify disease activity using SBCE,and there is good correlation between them.SBCE was shown to be useful for disease reclassification in patients who are suspected of having or who are diagnosed with CD,with a significant incremental diagnostic yield compared to other diagnostic modalities.Nine studies also demonstrated that the mucosal healing can be evaluated by SBCE to monitor the effect of medical treatment in patients with CD.This review also demonstrated that SBCE can detect post-operative recurrence to a similar extent as ileocolonoscopy,and proximal SB lesions that are beyond the reach of the colonoscope in over half of the patients.CONCLUSION SBCE could be incorporated in the treat-to-target algorithm for patients with CD.Randomized controlled trials are required to confirm its usefulness and reliability in this indication.
文摘Capsule endoscopy(CE) has proved to be an important non-invasive tool for diagnosis and monitoring Crohn's disease patients.It has the advantage of excellent visualization of digestive tract mucosa,a good tolerability and safety in well-selected patients.The risk of retention can be diminished by good selection of patients using imaging techniques and by the use of patency capsule.The aim of a capsule examination is not only an early diagnosis but also a very good stratification of prognosis,thus directing the treatment strategy for either a step up or top-down approach and also permitting the optimization of the treatment depending on the findings.When symptoms and biomarkers point to a change in the disease's activity we can either adjust the treatment directly as recommended in CALM study or choose in selected patients to visualize the digestive mucosa through a CE and take a decision afterwards.The appearance of the new capsule from Medtronicthe Pillcam Crohn's might be an important step forward in diagnosis,evaluating disease extent,the severity of the disease,prognosis,management in a treat to target approach,with treatment modifications according to the data from CE examination.Serial examinations in the same patient can be compared and a more objective evaluation of the lesions modification from one exam to another can be performed.We present the latest developments and current status and evidence that in selected patients capsule can be a tool in a treat to target approach.
文摘Objective To observe the clinical effect and efficacy of Xiaozhi Capsule (XZC) ,a Chinese medicine preparation for tonifying Gan-Shen,invigorating Pi to dissipate dampness (TGSIPDD) on total cholesterol (TC) ,triglyceride (TG) ,high-density lipoprotein cholesterol (HDLC) ,low-density lipoprotein cholesterol (LDL-C) 。
文摘There were 120 cases of mammary gland hyperplasia which were treated by using Chinese herbal medicine--Ru Zeng Nin capsule and obtained satisfied effect. It was proved benign disease by surgen hand check and puncture cytology, then divided them into two groups randomly. One group was Ru Zeng Nin capsule, another one was comparing. It was observed the condition about pain? tenderness? swelling piece after taking capsule half a year. The results showed that effective rate was 97 8%, cure rate was 80%. From this, we Rnow that Ru Zeng Nin capsule has better treatment effect to treast pain? mammary gland hypprplasia and fiber hyperplasia symptom. This capsule has safe and taking eary characteristic, so it’s easy to spread and opply in the clinical.
