There were differences between real boundary and blast hole controlling boundary of irregular mined-out area in underground metal mines. There were errors in numerical analysis of stability for goaf, if it was analyze...There were differences between real boundary and blast hole controlling boundary of irregular mined-out area in underground metal mines. There were errors in numerical analysis of stability for goaf, if it was analyzed as regular 3D mined-out area and the influence of coupling stress-seepage-disturbance was not considered adequately. Taking a lead zinc mine as the background, the model was built by the coupling of Surpac and Midas-Gts based on the goaf model precisely measured by CMS.According to seepage stress fundamental equations based on the equivalent continuum mechanical and the theory about equivalent load of dynamic disturbance in deep-hole blasting, the stability of mined-out area under multi-field coupling of stress-seepage-dynamic disturbance was numerically analyzed. The results show that it is more consistent between the numerical analysis model based on the real model of irregular 3D shape goaf and the real situation, which could faithfully reappear the change rule of stress–strain about the surrounding rock under synthetic action of blasting dynamic loading and the seepage pressure. The mined-out area multi-field coupling formed by blasting excavation is stable. Based on combination of the advantages of the CMS,Surpac and Midas-Gts, and fully consideration of the effects of multi-field coupling, the accurate and effective way could be provided for numerical analysis of stability for mined-out area.展开更多
Dynamic analysis steps and general flow of fast lagrangian analysis of continua in 3 dimensions(FLAC3D) were discussed. Numerical simulation for influence of excavation and blasting vibration on stability of mined-out...Dynamic analysis steps and general flow of fast lagrangian analysis of continua in 3 dimensions(FLAC3D) were discussed. Numerical simulation for influence of excavation and blasting vibration on stability of mined-out area was carried out with FLAC3D. The whole analytical process was divided into two steps, including the static analysis and the dynamic analysis which were used to simulate the influence of excavation process and blasting vibration respectively. The results show that the shape of right upper boundary is extremely irregular after excavation, and stress concentration occurs at many places and higher tensile stress appears. The maximum tensile stress is higher than the tensile strength of rock mass, and surrounding rock of right roof will be damaged with tension fracture. The maximum displacement of surrounding rock is 4.75 mm after excavation. However, the maximum displacement increases to 5.47 mm after the blasting dynamic load is applied. And the covering area of plastic zones expands obviously, especially at the foot of right upper slope. The analytical results are in basic accordance with the observed results on the whole. Damage and disturbance on surrounding rock to some degree are caused by excavation, while blasting dynamic load increases the possibility of occurrence of dynamic instability and destruction further. So the effective supporting and vibration reducing measures should be taken during mining.展开更多
To identify the instability on large scale underground mined-out area in the metal mine effectively,the parameters of radial basis function were determined through clustering method and the improved fuzzy radial basis...To identify the instability on large scale underground mined-out area in the metal mine effectively,the parameters of radial basis function were determined through clustering method and the improved fuzzy radial basis function neural network(FRBFNN)model of instability identification model about large scale underground mined-out area in the metal mine was built.The improved FRBFNN model was trained and tested.The results show that the improved FRBFNN model has high training accuracy and generalization ability.Parameters such as pillar area ratio,filling level and the value of rock quality designation have strong influence on instability of large scale underground mined-out area.Correctness of analysis about the improved FRBFNN model was proved by the practical application results about instability discrimination of surrounding rock in large-scale underground mined-out area of a metal mine in south China.展开更多
The engineering and geological characteristics of a steep slope consisting of coal gangue, rock and soil medium in Huating coal mine have been comprehensively investigated. Owing to humid weather, heavy rainfall, vege...The engineering and geological characteristics of a steep slope consisting of coal gangue, rock and soil medium in Huating coal mine have been comprehensively investigated. Owing to humid weather, heavy rainfall, vegetation and porous characteristics of the soil and rock mass, the steep slope will be destabilized and induce mud-rock flow or derive hazard easily. Firstly, based on the classical slope reinforcement theory, some regularity between the shear and displacement in the destabilized zone of the slope with or without root strength contribution is presented. Then, based on the experimental and statistical analysis of root strength, hydrological characteristics and stability status, etc., some possible biotechnical techniques for reinforcement of the steep slope have been suggested. These methods are important for quantitative analysis of destabilization of the slope and design of the biotechnical reinforcement.展开更多
The surface subsidence is a common environmental hazard in mined-out area. Based on careful analysis of the regularity of surface subsidence in mined-out area, we proposed a new time function based on Harris curve mod...The surface subsidence is a common environmental hazard in mined-out area. Based on careful analysis of the regularity of surface subsidence in mined-out area, we proposed a new time function based on Harris curve model in consideration of the shortage of current surface subsidence time functions. By analyzing the characteristics of the new time function, we found that it could meet the dynamic process, the velocity change process and the acceleration change process during surface subsidence. Then its rationality had been verified through project cases. The results show that the proposed time function model can give a good reflection of the regularity of surface subsidence in mined-out area and can accurately predict surface subsidence. And the prediction data of the model are a little greater than measured data on condition of proper measured data quantity, which is safety in the engineering. This model provides a new method for the analysis of surface subsidence in mined-out area and reference for future prediction, and it is valuable to engineering application.展开更多
AIM: To further evaluate the relationship between BSA and the effects of lamivudine in a greater number of cases and over a longer period of observation than in our previous evaluation. METHODS: We evaluated 249 pat...AIM: To further evaluate the relationship between BSA and the effects of lamivudine in a greater number of cases and over a longer period of observation than in our previous evaluation. METHODS: We evaluated 249 patients with chronic hepatitis B. The effects of treatment for one year (n = 249), two years (n = 147), and three years (n = 72) were evaluated from the levels of serum ALT and HBVoDNA, as biological and virological effects (undetectable levels by PCR), respectively. Moreover, several variables that could influence the response to treatment, including ALT, albumin, bilirubin, platelet counts, BSA, HBVoDNA, and HBeAg were analyzed. RESULTS: For 1-year treatment, multivariate analysis revealed that BSA (P = 0.0002) was the only factor for the biological effect, and that ALT (P = 0.0017), HBV- DNA (P = 0.0004), and HBeAg (P = 0.0021) were independent factors for the virological effect. For 2-year treatment, multivariate analysis again showed that BSA (P = 0.0147) was the only factor for the biological effect, and that ALT (P = 0.0192) and HBeAg (P = 0.0428) were independent factors for the virological effect. For 3-year treatment, multivariate analysis, however, could not reveal BSA (P = 0.0730) as a factor for the normalization of ALT levels. CONCLUSION: BSA is a significant predictor for the normalizing the effect of lamivudine therapy on ALT for an initial 2-year period, suggesting that lamivudine dosage should be based on the individual BSA.展开更多
Through the Betula nigra afforestation test in the engineering treatment area of the Wuxi Section of the Daning River in Chongqing,the feasibility of arbor vegetation restoration in the comprehensive management of the...Through the Betula nigra afforestation test in the engineering treatment area of the Wuxi Section of the Daning River in Chongqing,the feasibility of arbor vegetation restoration in the comprehensive management of the engineering treatment areas of the Three Gorges Reservoir was explored.The results showed that:(1)before the flooding in the project area,the survival rate of B.nigra seedlings was high,over 95%,and(2)in 2021,after a water storage period,affected by factors such as seedling specifications,flood and flooding time,the survival rate of the seedlings planted in 2020 was low,and the one-year-old seedlings were greatly competed by weeds and grew less.Two-year-old B.nigra seedlings were replanted in 2021,and the survival rate of the B.nigra seedlings was 100%in 2022.Two-year-old B.nigra seedlings have strong adaptability and have little impact on the stability of the engineering treatment area,and can be used as afforestation tree species in engineering treatment areas of hydro-fluctuation zones.展开更多
Constructed wetlands (CWs) can achieve a high-quality wastewater treatment and a quality that meets the prescribed standard, defined by legislation on wastewater discharge. A limitation in the application of construct...Constructed wetlands (CWs) can achieve a high-quality wastewater treatment and a quality that meets the prescribed standard, defined by legislation on wastewater discharge. A limitation in the application of constructed wetlands (CWs) is the large area requirement, which limits their application. The subject matter of this research is to check the possibility of improving the efficiency of wastewater treatment and reducing the required area for constructed wetlands (CWs) by using an adequate substrate under the conditions found in Montenegro. In the described experiment, the constructed wetlands (CW) have a vertical flow system and play the role of a secondary wastewater treatment, receiving water from the existing WWTP in Podgorica after the primary treatment. These vertical flow systems reflect experience with the use of similar systems in Slovenija, Austria and Italy. Measurements to date show that the substrate plays an important role and that wastewater treatment efficacy varies significantly with respect to the type of substrate when used under the conditions available in Montenegro.展开更多
Effective landscape-scale fuel management strategies are essential for reducing wildfire risk in Mediterranean fire-prone areas.In this study,the minimum travel time(MTT)fire-spread algorithm as implemented in FlamMap...Effective landscape-scale fuel management strategies are essential for reducing wildfire risk in Mediterranean fire-prone areas.In this study,the minimum travel time(MTT)fire-spread algorithm as implemented in FlamMap was applied to assess the potential of alternative fuel treatments for lowering wildfire losses in a 5,740-ha study area in eastern Sardinia,Italy.Twenty-seven wildfires at 10-m resolution were simulated considering three wind speeds(15,18,and 21 km h-1)to compare fuel treatments:no treatment(NT),irrigated agroforestry areas with shrub clearing(T1),prescribed fire in eucalyptus stands(T2),and irrigated grasslands(T3).The simulations replicated a recent large wildfire that occurred in the study area(Orrìwildfire,2019)and considered the weather and fuel moisture conditions associated with this event.The average wildfire exposure outputs(burned area,probability of burning,conditional flame length,potential crown fire occurrence,and surfaces withflame lengths above 2.5 m)decreased after fuel treatments,compared to no treatment.T1 was the most effective strategy in mitigating wildfire hazards and provided the most significant performance for several wildfire exposure indicators.Treating only 0.5%of the study area(~30 ha)resulted in a decrease in all wildfire exposure metrics to~10%within the study area.In addition,the total surface characterized by high flame length(average>2.5 m)was the lowest in the T1 treatment.This study can help land and fire managers optimize fuel treatment opportunities and wildfire risk mitigation strategies in Mediterranean areas.展开更多
基金Project(2012BAK09B02-05)supported by the National"Twelfth Five"Science and Technology Support Program,ChinaProject(51274250)supported by the National Natural Science Foundation of China+2 种基金Project(2013zzts057)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(11KF02)supported by the Research Fund of the State Key Laboratory of Coal Resources and Mine safety,CUMT,ChinaProject(2012M511417)supported by China Postdoctoral Science Foundation
文摘There were differences between real boundary and blast hole controlling boundary of irregular mined-out area in underground metal mines. There were errors in numerical analysis of stability for goaf, if it was analyzed as regular 3D mined-out area and the influence of coupling stress-seepage-disturbance was not considered adequately. Taking a lead zinc mine as the background, the model was built by the coupling of Surpac and Midas-Gts based on the goaf model precisely measured by CMS.According to seepage stress fundamental equations based on the equivalent continuum mechanical and the theory about equivalent load of dynamic disturbance in deep-hole blasting, the stability of mined-out area under multi-field coupling of stress-seepage-dynamic disturbance was numerically analyzed. The results show that it is more consistent between the numerical analysis model based on the real model of irregular 3D shape goaf and the real situation, which could faithfully reappear the change rule of stress–strain about the surrounding rock under synthetic action of blasting dynamic loading and the seepage pressure. The mined-out area multi-field coupling formed by blasting excavation is stable. Based on combination of the advantages of the CMS,Surpac and Midas-Gts, and fully consideration of the effects of multi-field coupling, the accurate and effective way could be provided for numerical analysis of stability for mined-out area.
基金Project (50490272) supported by the National Natural Science Foundation of China project(NCET-05-0687) supportedby Programfor New Century Excellent Talents project (040109) supported bythe Doctor Degree Paper Innovation Engineering of CentralSouth University
文摘Dynamic analysis steps and general flow of fast lagrangian analysis of continua in 3 dimensions(FLAC3D) were discussed. Numerical simulation for influence of excavation and blasting vibration on stability of mined-out area was carried out with FLAC3D. The whole analytical process was divided into two steps, including the static analysis and the dynamic analysis which were used to simulate the influence of excavation process and blasting vibration respectively. The results show that the shape of right upper boundary is extremely irregular after excavation, and stress concentration occurs at many places and higher tensile stress appears. The maximum tensile stress is higher than the tensile strength of rock mass, and surrounding rock of right roof will be damaged with tension fracture. The maximum displacement of surrounding rock is 4.75 mm after excavation. However, the maximum displacement increases to 5.47 mm after the blasting dynamic load is applied. And the covering area of plastic zones expands obviously, especially at the foot of right upper slope. The analytical results are in basic accordance with the observed results on the whole. Damage and disturbance on surrounding rock to some degree are caused by excavation, while blasting dynamic load increases the possibility of occurrence of dynamic instability and destruction further. So the effective supporting and vibration reducing measures should be taken during mining.
基金financially supported by the National"Twelfth-Five-Year"Science&Technology Support Plan(No.2012BAK09B02-05)the National Natural Science Foundation of China(No.51274250)
文摘To identify the instability on large scale underground mined-out area in the metal mine effectively,the parameters of radial basis function were determined through clustering method and the improved fuzzy radial basis function neural network(FRBFNN)model of instability identification model about large scale underground mined-out area in the metal mine was built.The improved FRBFNN model was trained and tested.The results show that the improved FRBFNN model has high training accuracy and generalization ability.Parameters such as pillar area ratio,filling level and the value of rock quality designation have strong influence on instability of large scale underground mined-out area.Correctness of analysis about the improved FRBFNN model was proved by the practical application results about instability discrimination of surrounding rock in large-scale underground mined-out area of a metal mine in south China.
基金This work was financially supported by the National Natural Science Foundation of China (No. 10402033) and the Key Lab. Foun-dation of the Ministry of Education of China (No.04JS19).
文摘The engineering and geological characteristics of a steep slope consisting of coal gangue, rock and soil medium in Huating coal mine have been comprehensively investigated. Owing to humid weather, heavy rainfall, vegetation and porous characteristics of the soil and rock mass, the steep slope will be destabilized and induce mud-rock flow or derive hazard easily. Firstly, based on the classical slope reinforcement theory, some regularity between the shear and displacement in the destabilized zone of the slope with or without root strength contribution is presented. Then, based on the experimental and statistical analysis of root strength, hydrological characteristics and stability status, etc., some possible biotechnical techniques for reinforcement of the steep slope have been suggested. These methods are important for quantitative analysis of destabilization of the slope and design of the biotechnical reinforcement.
基金supported by the Key Program of the National Natural Science Foundation of China (No. 50334060)
文摘The surface subsidence is a common environmental hazard in mined-out area. Based on careful analysis of the regularity of surface subsidence in mined-out area, we proposed a new time function based on Harris curve model in consideration of the shortage of current surface subsidence time functions. By analyzing the characteristics of the new time function, we found that it could meet the dynamic process, the velocity change process and the acceleration change process during surface subsidence. Then its rationality had been verified through project cases. The results show that the proposed time function model can give a good reflection of the regularity of surface subsidence in mined-out area and can accurately predict surface subsidence. And the prediction data of the model are a little greater than measured data on condition of proper measured data quantity, which is safety in the engineering. This model provides a new method for the analysis of surface subsidence in mined-out area and reference for future prediction, and it is valuable to engineering application.
文摘AIM: To further evaluate the relationship between BSA and the effects of lamivudine in a greater number of cases and over a longer period of observation than in our previous evaluation. METHODS: We evaluated 249 patients with chronic hepatitis B. The effects of treatment for one year (n = 249), two years (n = 147), and three years (n = 72) were evaluated from the levels of serum ALT and HBVoDNA, as biological and virological effects (undetectable levels by PCR), respectively. Moreover, several variables that could influence the response to treatment, including ALT, albumin, bilirubin, platelet counts, BSA, HBVoDNA, and HBeAg were analyzed. RESULTS: For 1-year treatment, multivariate analysis revealed that BSA (P = 0.0002) was the only factor for the biological effect, and that ALT (P = 0.0017), HBV- DNA (P = 0.0004), and HBeAg (P = 0.0021) were independent factors for the virological effect. For 2-year treatment, multivariate analysis again showed that BSA (P = 0.0147) was the only factor for the biological effect, and that ALT (P = 0.0192) and HBeAg (P = 0.0428) were independent factors for the virological effect. For 3-year treatment, multivariate analysis, however, could not reveal BSA (P = 0.0730) as a factor for the normalization of ALT levels. CONCLUSION: BSA is a significant predictor for the normalizing the effect of lamivudine therapy on ALT for an initial 2-year period, suggesting that lamivudine dosage should be based on the individual BSA.
基金Supported by Chongqing Technology Innovation and Application Development General Project(cstc2019jscx-msxmX0335)。
文摘Through the Betula nigra afforestation test in the engineering treatment area of the Wuxi Section of the Daning River in Chongqing,the feasibility of arbor vegetation restoration in the comprehensive management of the engineering treatment areas of the Three Gorges Reservoir was explored.The results showed that:(1)before the flooding in the project area,the survival rate of B.nigra seedlings was high,over 95%,and(2)in 2021,after a water storage period,affected by factors such as seedling specifications,flood and flooding time,the survival rate of the seedlings planted in 2020 was low,and the one-year-old seedlings were greatly competed by weeds and grew less.Two-year-old B.nigra seedlings were replanted in 2021,and the survival rate of the B.nigra seedlings was 100%in 2022.Two-year-old B.nigra seedlings have strong adaptability and have little impact on the stability of the engineering treatment area,and can be used as afforestation tree species in engineering treatment areas of hydro-fluctuation zones.
文摘Constructed wetlands (CWs) can achieve a high-quality wastewater treatment and a quality that meets the prescribed standard, defined by legislation on wastewater discharge. A limitation in the application of constructed wetlands (CWs) is the large area requirement, which limits their application. The subject matter of this research is to check the possibility of improving the efficiency of wastewater treatment and reducing the required area for constructed wetlands (CWs) by using an adequate substrate under the conditions found in Montenegro. In the described experiment, the constructed wetlands (CW) have a vertical flow system and play the role of a secondary wastewater treatment, receiving water from the existing WWTP in Podgorica after the primary treatment. These vertical flow systems reflect experience with the use of similar systems in Slovenija, Austria and Italy. Measurements to date show that the substrate plays an important role and that wastewater treatment efficacy varies significantly with respect to the type of substrate when used under the conditions available in Montenegro.
基金funded by"MED-Star"(Grant No.E88H19000120007)“Med-Foreste”(grant no.B85I1900010007)+5 种基金“Med-Coopfi re”(Grant No.B81I1900010007)projectssupported by the European Union under the cross-border Programma Italia-Francia Marittimo 2014–2020the“FOE2019-Climate Change:risk mitigation for sustainable development”(Ministerial Decree no.856/19)projectfunded by the Italian Ministry of EducationUniversity and Research(MIUR)co-financed by the University of Sassari,Fondo di Ateneo per la Ricerca Scientifica(FAR)2020。
文摘Effective landscape-scale fuel management strategies are essential for reducing wildfire risk in Mediterranean fire-prone areas.In this study,the minimum travel time(MTT)fire-spread algorithm as implemented in FlamMap was applied to assess the potential of alternative fuel treatments for lowering wildfire losses in a 5,740-ha study area in eastern Sardinia,Italy.Twenty-seven wildfires at 10-m resolution were simulated considering three wind speeds(15,18,and 21 km h-1)to compare fuel treatments:no treatment(NT),irrigated agroforestry areas with shrub clearing(T1),prescribed fire in eucalyptus stands(T2),and irrigated grasslands(T3).The simulations replicated a recent large wildfire that occurred in the study area(Orrìwildfire,2019)and considered the weather and fuel moisture conditions associated with this event.The average wildfire exposure outputs(burned area,probability of burning,conditional flame length,potential crown fire occurrence,and surfaces withflame lengths above 2.5 m)decreased after fuel treatments,compared to no treatment.T1 was the most effective strategy in mitigating wildfire hazards and provided the most significant performance for several wildfire exposure indicators.Treating only 0.5%of the study area(~30 ha)resulted in a decrease in all wildfire exposure metrics to~10%within the study area.In addition,the total surface characterized by high flame length(average>2.5 m)was the lowest in the T1 treatment.This study can help land and fire managers optimize fuel treatment opportunities and wildfire risk mitigation strategies in Mediterranean areas.