Investigation of Hepatitis C Virus Infection Rate of Patients in a General Hospital

Objective To investigate the infection rate of hepatitis C virus among the ambulatory patients and in-patients of a tertiary teaching hospital,and study the demographic factors related to the prevalence of hepatitis C virus infection.Methods All patients tested for hepatitis C virus antibody from July 2008 to July 2009 in Peking Union Medical College Hospital were enrolled in this cross-sectional analysis.The prevalence of hepatitis C virus infection was compared according to age,gender,and departments,respectively.Among patients with positive serology hepatitis C virus marker,the positivity of hepatitis C virus RNA was analysed.Results Among 29 896 subjects included,the hepatitis C virus antibody of 494 patients were positive(1.7%).When patients were divided into 9 age groups,the age specific prevalence of hepatitis C virus antibody were0.2%,1.7%,1.2%,1.1%,1.5%,1.9%,2.6%,2.4%and 2%,respectively.The prevalence of hepatitis C virus antibody in non-surgical department and surgical department was 3%and 1%,respectively.The prevalence of hepatitis C virus antibody of males was higher than that of the females.Total of 194 patients with positive hepatitis C virus antibody were tested for hepatitis C virus RNA,the RNA level of 113 patients(58.2%)were higher than the low detection limit.Conclusions The prevalence of hepatitis C virus antibody was relatively high among patients of general tertiary hospital.Age group of 60-69,males and patients in non-surgical departments were factors associated with high rate of hepatitis C virus infection.

Influencing Factors and Mortality Prediction of Covid-19 Contact Infection Rate in China

Taking the COVID-19 data from 2020-1-23 to 3-21 days released by the China Health Protection Committee as the sample,the hospital remaining rate,mortality rate and cure rate are selected as covariates,and the contact infection rate is used as response variable to establish a high precision ADL model,results of return substitution show that the predicted value of contact infection rate almost coincides with the sample value,and shows three stages of change characteristics.After March 1,2020,the overall trend is downward,stable below 12%.Main influencing factors of contact infection rate are analyzed quantitatively.Based on this,the ARIMA(1,2,2)model is established to analyze and predict the mortality change trend.The results showed that the domestic COVID-19 mortality rate is stable near 4%after 2020-3-27.

Quantitative assessment of the infection rate of the entomophthoraceous fungus, Zoophthora anhuiensis against the green peach aphid Myzus persicae

A two-step method was developed to quantitatively assess the infection rate of the entomophthoraceous fungus, Zoophthora anhuiensis (Li) Humber, on the green peach aphid, Myzus persicae (Sulzer) .Firstly, a standard time-dose-mortality relationship, established by modeling data from bioassay 1 at varying conidial dosages (0.4- 10.4 conidia/mm^2) of Z. anhuiensis F97028, was used to yield an estimate of expected mortality probability at a given dosage. Secondly, bioassay 2 was conducted by simultaneously exposing six ≤4-day-old nymphal colonies to a shower of Z. anhuiensis conidia at each of four dosages (resulting from exposures of 0.3 - 8.0 min) . Subsequently, the colonies were separately immersed in a 0.1% chlorothalonil solution for 0.5 min to disinfect all surviving conidia on the host integument from 1 - 12 h after exposure under temperature treatments of 15 and 20℃, respectively. The infection rate during a specific period from the end of the exposure to the immersion was then estimated as the ratio of the observed mortality over the expected mortality probability at a particular dosage. The results showed that the infection of M. persicae from Z. anhuiensis was highly rapid with little difference between aphid colonies maintained at 15 and 20℃ before being immersed in the fungicidal solution after exposure. The first 6-hour period after exposure was most crucial to successful infection of the fungus with the infection rate greatly depending on conidial dosages. It took ≤ 1 h to infect > 50% of the aphids at a dosage of > 1.5 conida/mm^2 and > 90% at > 50 conidia/mm^2 .

Analysis of the Influence of Operating Room Nursing Care Management on the Incidence Rate of Nosocomial Infection in Orthopedic Surgery Patients

Objective:To analysis the influence of operating room nursing care management on the incidence rate of nosocomial infection in orthopedic surgery patients.Methodology:Fifty six orthopedic surgery patients who admitted into the hospital between January to December 2018 were enrolled into this study and randomly divided into two groups,which were the control group(under general management)and the observation group(under the operating room nursing care management).Further,the incidence rate of nosocomial infections,the incidence rate of irregular nursing care phenomena,the satisfaction score of nursing care management,and the quality of life score were observed and recorded.Result:The incidence rate of nosocomial infection,the incidence rate of irregular nursing care management,the satisfaction score of nursing care management,and the quality of life score of the observation group were compared to that of the control group,and the result showed P<0.05,indicates the statistical significance between the data indicators.Conclusion:The use of operating room nursing care management in patients with orthopedic surgery has shown a significant effect.

Prediction and rate of infections in diabetes mellitus patients with diabetes ketoacidosis in Penang, Malaysia

Study aimed to determine the rate and prediction of infection in diabetes mellitus patients ≥18 year, with diabetic ketoacidosis (DKA). Retrospective cohort study design was adopted to achieve the objectives. Universal sampling technique was employed for data collection among Diabetes ketoacidosis patients, over a period of 3 years (Jan 2008-Dec 2010). Statistical package for social sciences used to analyze data. Over a 3-year period, total of 967 admissions were identified. Of it, 112 (11.6%) with no infection, 679 (70.2%) with bacterial infection and 176 (18.2%) with presumed viral infection. The mean WBC for all the patients was 18,177 (±9431). 721 (74.6%) had leukocytosis, as defined by a WBC ≥ 15,000/mm3. WBC, differential, leukocytosis, as well as sex, temperature were not significant predictors (p > 0.05) of bacterial infection. There was significant (p < 0.05) difference of age between the 3 groups, age above 57 years have high rate of infection as compared to age below and equal 57 years. The infection rate in elderly patients with DKA was high and majority of them had lack of clinical evidence. Major bacterial infections with potential serious sequel were particularly common (33.3%), among every third patient being presumed to have serious consequences.

No Effects of Meteorological Factors on the SARS-CoV-2 Infection Fatality Rate

Objective Previous studies have shown that meteorological factors may increase COVID-19 mortality,likely due to the increased transmission of the virus.However,this could also be related to an increased infection fatality rate(IFR).We investigated the association between meteorological factors(temperature,humidity,solar irradiance,pressure,wind,precipitation,cloud coverage)and IFR across Spanish provinces(n=52)during the first wave of the pandemic(weeks 10–16 of 2020).Methods We estimated IFR as excess deaths(the gap between observed and expected deaths,considering COVID-19-unrelated deaths prevented by lockdown measures)divided by the number of infections(SARS-CoV-2 seropositive individuals plus excess deaths)and conducted Spearman correlations between meteorological factors and IFR across the provinces.Results We estimated 2,418,250 infections and 43,237 deaths.The IFR was 0.03%in<50-year-old,0.22%in 50–59-year-old,0.9%in 60–69-year-old,3.3%in 70–79-year-old,12.6%in 80–89-year-old,and26.5%in≥90-year-old.We did not find statistically significant relationships between meteorological factors and adjusted IFR.However,we found strong relationships between low temperature and unadjusted IFR,likely due to Spain’s colder provinces’aging population.Conclusion The association between meteorological factors and adjusted COVID-19 IFR is unclear.Neglecting age differences or ignoring COVID-19-unrelated deaths may severely bias COVID-19 epidemiological analyses.

Patterns of tsetse abundance and trypanosome infection rates among habitats of surveyed villages in Maasai steppe of northern Tanzania

Background:Changes of land cover modify the characteristics of habitat,host-vector interaction and consequently infection rates of disease causing agents.In this paper,we report variations in tsetse distribution patterns,abundance and infection rates in relation to habitat types and age in the Maasai Steppe of northern Tanzania.In Africa,Tsetse-transmitted trypanosomiasis negatively impacted human life where about 40 million people are at risk of contracting the disease with dramatic socio-economical consequences,for instance,loss of livestock,animal productivity,and manpower.Methods:We trapped tsetse flies in dry and wet seasons between October 2014 and May 2015 in selected habitats across four villages:Emboreet,Loiborsireet,Kimotorok and Oltukai adjacent to protected areas.Data collected include number and species of tsetse flies caught in baited traps,PCR identification of trypanosome species and extraction of monitored Normalized Difference Vegetation Index(NDVI)data from Moderate Resolution Imaging Spectrometer(MODIS).Results:Our findings demonstrate the variation of tsetse fly species abundance and infection rates among habitats in surveyed villages in relation to NDVI and host abundance.Results have shown higher tsetse fly abundance in Acacia-swampy ecotone and riverine habitats for Emboreet and other villages,respectively.Tsetse abundance was inconsistent among habitats in different villages.Emboreet was highly infested with Glossina swynnertoni(68%)in ecotone and swampy habitats followed by G.morsitans(28%)and G.pallidipes(4%)in riverine habitat.In the remaining villages,the dominant tsetse fly species by 95%was G.pallidipes in all habitats.Trypanosoma vivax was the most prevalent species in all infected flies(95%)with few observations of co-infections(with T.congolense or T.brucei).Conclusions:The findings of this study provide a framework to mapping hotspots of tsetse infestation and trypanosomiasis infection and enhance the communities to plan for effective control of trypanosomiasis.

Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in Prevention and Control of Multi-drug Resistance Infection

Objective Contact precautions,especially the initiation of isolation,are important measures to prevent and control multidrug-resistant organisms(MDROs).However,the implementation in clinical practice remains weak.This study aimed to analyze the impact of multidisciplinary collaborative intervention on isolation implementation in multidrug-resistant infection,and determine the factors that affect the implementation of isolation measures.Methods A multidisciplinary collaborative intervention related to isolation was conducted at a teaching tertiary hospital in central China on November 1,2018.The information of 1338 patients with MDRO infection and colonization at 10 months before and after the intervention was collected.Then,the issuance of isolation orders was retrospectively analyzed.Univariate analysis and multivariate logistic regression analysis were performed to analyze the factors that affected the isolation implementation.Results The overall issuance rate of isolation orders was 61.21%,which increased from 33.12%to 75.88%(P<0.001)after the implementation of the multidisciplinary collaborative intervention.The intervention(P<0.001,OR=0.166)was a promoting factor for the issuance of isolation orders,in addition to the length of stay(P=0.004,OR=0.991),department(P=0.004),and microorganism(P=0.038).Conclusion The isolation implementation remains far lower than policy standards.Multidisciplinary collaborative interventions can effectively improve the compliance to isolation measures implemented by doctors,thereby promoting the standardized management of MDROs,and providing reference for further improving the quality of hospital infection management.

Risk factors and strategy for surgical incision infection in department of abdominal surgery

Objective To study the risk factors of surgical wound infection among the patients in department of abodominal surgery. Methods The factors on surgical wound infection were investigated by retrospective study. The diagnosis standard was based on Diagnosis Standard of Hospital Infection published by Ministry of Health.

2016—2020年武汉市医院感染横断面调查结果趋势研究

目的 了解武汉市医疗机构医院感染和社区感染现状,分析医院感染的流行趋势与管理重点。方法 采用病历调查和床旁调查相结合的方法,按照全国医院感染监控管理培训基地制定的全国医院感染横断面调查表进行调查,分析2016、2018、2020年的调查数据。结果 2016、2018、2020年武汉市医院感染现患率分别为2.66%、2.21%、1.85%,社区感染现患率分别为17.81%、17.82%、16.29%,均呈下降趋势(均P<0.05)。医院感染现患率较高的科室为综合重症监护病房(ICU)、血液病科(组)、神经外科、胸外科、儿科新生儿组;社区感染现患率较高的科室为儿科非新生组、呼吸科(组)、感染病科(组)、综合ICU、儿科新生儿组。医院感染、社区感染感染部位均以下呼吸道为主,其中2016、2018、2020年术后下呼吸道医院感染构成比分别为12.85%、18.39%、22.09%。2016、2018、2020年手术部位医院感染现患率分别为0.99%、0.82%、0.69%。医院感染、社区感染病原体均以革兰阴性菌为主。结论 2016、2018、2020年武汉市医疗机构医院感染管理取得了较好的成效,但综合ICU、下呼吸道医院感染等问题仍需在后期工作中强化改进。

北京地区育龄男性与女性TORCH感染情况回顾分析

目的 回顾分析近2016年7月至2022年12月来我院就诊人群的TORCH感染情况,为本地区优生优育工作提供数据参考。方法 利用酶联免疫吸附实验检测男性和非妊娠期女性血清中TORCH各病原体IgG抗体和IgM抗体的阳性情况,对数据进行处理分析。结果 进行TORCH检测的人群,女性人数远高于男性人数;男性和女性之间TOX、RV、CMV和HSV的IgM抗体阳性率均存在差异,男性和女性之间TOX和HSV的所有感染模式存在差异,且所有差异均表现为女性的抗体阳性率高于男性的抗体阳性率;男性RV和CMV的IgM抗体阳性率在不同的季节存在差异,女性的TOX、RV、CMV和HSV-1的IgM抗体阳性率在不同的季节存在差异;男、女性HSV-1和HSV-2抗体IgM阳性率在各季节均存在差异,且男、女性HSV-2的所有感染模式在各个季节中也完全不同;在合并感染中,男、女性的IgG抗体阳性率均以RV+CMV、RV+HSV-1、CMV+HSV-1和RV+CMV+HSV-1为主,且女性的抗体阳性率高于男性,在IgM抗体的阳性率分析中,女性主要以HSV-1+HSV-2为主,男性主要以RV+HSV-1为主,其女性的抗体阳性率也远高于男性。结论 本地区TORCH感染人群主要为女性,TORCH感染的病原体有季节性差异,可针对此特点进行预防;建议增加育龄男性检测TORCH相关项目,可有助于夫妇备孕期感染的预防。

产妇及新生儿单核细胞增生李斯特菌感染情况分析

目的探讨该院单核细胞增生李斯特菌(简称单增李斯特菌)感染发病情况及预防治疗措施。方法回顾性选取2012-2021年该院检出的单增李斯特菌阳性病例为研究对象,统计分析其科室分布、发病及抗感染治疗情况。结果检出的阳性病例为产妇及其分娩新生儿。产科出院患者单增李斯特菌感染率为7.63/100000,分娩新生儿单增李斯特菌感染率为4.68/100000。全院产妇、新生儿单增李斯特菌感染率为5.32/100000。感染产妇分娩新生儿死亡率与正常分娩产妇的新生儿死亡率比较,差异有统计学意义(P<0.05)。经验性抗感染治疗,产妇用药选择针对单核李斯特菌敏感的青霉素类抗菌药物的病例数远少于新生儿,二者比较差异有统计学意义(P<0.05)。结论产妇单增李斯特菌感染率虽低,但危害大,经验性抗感染治疗应首选对单增李斯特菌敏感的抗菌药物。

郑州地区土源性线虫感染监测检验结果分析

目的调查分析郑州地区土源性线虫感染率及流行特征情况,为制定防治措施提供参考。方法于2016—2022年对郑州登封市、管城回族区、上街区、中原区、金水区、二七区、惠济区、航空港区、新密市设置监测点进行监测,每个地区根据东、南、西、北、中划分为5个行政村,通过整群抽样方法每个行政村抽取3周岁以上的常住居民(外来居民住满1年以上、本地居民住满6个月及以上)至少200人,每个监测点至少1000人作为研究对象。所有监测对象采集粪便样本约30 g,利用改良加藤厚涂片法(一粪两检)检测土源性线虫虫卵情况,计算出土源性线虫感染情况,3~9周岁的儿童通过透明胶纸肛拭法增加蛲虫检测,分析土源性线虫感染各年感染情况及各虫卵感染情况,以及各人群土源性线虫感染情况。结果郑州共调查10437人,检出土源性线虫感染共32人,感染率为0.31%(32/10437),其中蛔虫3例,感染率为0.03%(3/10437),蛲虫29例,感染率为0.28%(29/10437),无钩虫、鞭虫感染。2016年土源性线虫感染率最高为1.33%(14/1052),2017年、2019年与2020年均未检出感染者,土源性线虫不同年份间感染率对比差异显著(χ^(2)=51.807,P<0.001)。登封市土源性线虫感染率最高1.33%(14/1052),管城回族区、中原区、金水区、二七区、惠济区、航空港区均未检出感染者,土源性线虫不同地区间感染率对比差异显著(χ^(2)=63.263,P<0.001)。男性土源性线虫感染率为0.20%(10/4947),女性感染率为0.40%(22/5490),土源性线虫不同性别间感染率对比无明显差异(χ^(2)=3.357,P=0.067);3~9岁年龄组土源性线虫感染率最高0.72%(11/1535),20~49岁年龄组感染率最低0.07%(1/1369),土源性线虫不同年龄组间感染率对比差异显著(χ^(2)=20.416,P=0.001);农民土源性线虫感染率最高0.52%(13/2478),医务人员及其他职业感染率最低0.14%(3/2091),土源性线虫不同职业间感染率对比无明显差异(χ^(2)=7.148,P=0.128);文盲/半文盲土源性线虫感染率最高0.80%(7/875),大专及以上学历人群感染率最低0.14%(4/2822),土源性线虫不同文化程度间感染率对比差异显著(χ^(2)=24.007,P<0.001)。结论蛲虫为郑州市地区土源性线虫病虫种,登封市为重点地区,女性、3~9岁儿童、农民、文盲/半文盲为高危人群,应加强郑州市重点地区及高危人群土源性线虫病防治管理。

可控负压吸引下输尿管软镜钬激光碎石术治疗肾结石合并尿路感染的疗效分析

目的 分析肾结石且伴有尿路感染患者应用可控负压吸引下输尿管软镜钬激光碎石术治疗的临床效果。方法 80例肾结石合并尿路感染患者,将样本经随机法分为实验组和对照组,每组40例。对照组患者接受常压输尿管软镜钬激光碎石术治疗,实验组患者接受可控负压吸引下输尿管软镜钬激光碎石术治疗。比较两组患者术后住院时间、术后血尿时间、手术时间、术后结石清除率及术后感染发生情况。结果 实验组患者的术后住院时间(2.55±1.45)d、术后血尿时间(1.13±0.56)d、手术时间(42.30±4.24)min明显短于对照组的(4.00±2.35)d、(2.20±0.65)d、(63.03±6.33)min(P<0.05)。实验组患者的术后感染发生率为12.5%(5/40),相比于对照组的40.0%(16/40)低(P<0.05),手术更安全、可靠。实验组患者的术后结石清除率97.5%(39/40)显著高于对照组的82.5%(33/40)(P<0.05),术后残石率更低。结论 可控负压吸引下输尿管软镜钬激光碎石术应用于肾结石合并尿路感染治疗中,能够有效缩短住院时间及手术时间,提高术后结石清除率,降低患者术后发热发生率,安全有效。

突发事件下的封闭空间情绪传播模型研究

为避免突发事件中复杂情绪在封闭空间内无序发酵引发衍生灾害,探索封闭空间的情绪传播规律,基于情绪自发传播模型SISa,考虑封闭空间个体情绪的差异性、群体极化现象、特殊情绪交互方式以及危急情景下的动态感染率,分别改进主体情绪状态、情绪转移路径、交互模式与感染率,提出1种适用于封闭空间的情绪传播模型SE 4Sa,并以武汉地铁2号线为例完成数值仿真与敏感性分析。研究结果表明:情绪自发转移过程对限制负面情绪累积起到关键作用,且情绪极化现象使系统危险性大幅增长;缩减个体情绪感知域使系统稳定时间缩短90.6%、高唤醒负面情绪占比下降27.4%;突发事件下的动态感染率更符合封闭空间情绪传播特性。研究结果可为突发事件下封闭空间的群体行为和群体情绪规律研究提供理论支持。

2021—2023年邹城市土源性线虫病监测结果分析

目的:了解邹城市土源性线虫病感染现状,掌握其流行规律及影响因素,为相关部门制定防治策略提供科学依据。方法:2021—2023年选取邹城市常住居民3165人作为研究对象,每年收集常住居民的粪便样本,采用改良加藤厚涂片法检验。结果:在3165名常住居民中,检出土源性线虫病感染16人,总感染率为0.51%,其中鞭虫、蛔虫和蛲虫感染率分别为0.03%、0.03%和0.44%;不同年份土源性线虫病感染率比较,差异有统计学意义(χ^(2)=9.002,P<0.05);2021—2023年邹城市不同性别、不同年龄段、不同职业、不同文化程度人群土源性线虫病感染率比较,差异无统计学意义(P>0.05)。结论:邹城市已达到土源性线虫病传播控制与阻断标准,应加大健康教育宣传,提高人群对土源性线虫病的认识程度,开展重点人群驱虫防治工作,降低人群感染率,加强无害化厕所管理。完善人民健康促进政策,把保障人民健康放在优先发展的战略位置,从而进一步巩固阻断土源性线虫病防治成果。

公民器官捐献供体质量对肝移植术后受体生存率的影响

目的探讨心脏死亡器官捐献(donation after cardiac death,DCD)供体质量对肝移植术后受体生存率的影响。方法回顾性分析2018年1月至2021年1月解放军总医院第三医学中心DCD肝移植手术患者100例,移植术后进行为期1年的随访调查,观察肝移植受者的生存状态,对相关危险因素加以分析。结果100例肝移植受者术后1年病死率为3%(3/100),其死亡因素与供体冷缺血时间、供体脂肪肝、术中出血量、供体白蛋白及总胆红素水平、肝细胞水肿密切相关(P<0.05)。多因素Logistic回归分析发现,供体冷缺血时间≥840 min、脂肪肝是影响肝移植受者生存状态的独立危险因素(P<0.05)。肝移植术后感染率为26%(26/100),其肝移植术后感染率与受体肝功能Child-Pugh评分、术前血红蛋白水平、血小板计数、术中输血量、术后重症监护病房(intensive care unit,ICU)留观时间密切相关(P<0.05)。结论DCD供体质量对肝移植术后受体生存率具有显著影响,供体冷缺血时间、供体脂肪肝对肝移植术后受体生存状态具有重要影响。

NEUT、ESR、Gal-3水平与感染性心内膜炎患者临床预后的关系

目的探讨中性粒细胞计数(neutrophil count,NEUT)、红细胞沉降率(erythrocyte sedimentation rate,ESR)、半乳糖凝集素-3(galectin-3,Gal-3)水平与感染性心内膜炎(infective endocarditis,IE)患者临床预后的关系。方法选取2021年2月至2023年4月商洛市中心医院收治的88例IE患者,其中男49例,女39例,平均年龄46.20岁,心功能分级Ⅱ~Ⅲ级54例、Ⅳ级34例。随访1年,根据预后结果,将患者分为预后良好组(54例)和预后不良组(34例)。单因素分析患者的临床资料和实验室指标等,然后通过多因素logistic回归分析IE患者预后不良的危险因素。受试者操作特征曲线(ROC)评估NEUT、ESR和Gal-3水平对IE患者预后不良的预测能力。采用t检验、χ^(2)检验。结果预后不良组与预后良好组心功能分级、Pitt评分、治疗前NEUT水平、治疗2周后NEUT、ESR和Gal-3水平比较,差异均有统计学意义(均P<0.05)。多因素logistic回归分析结果显示,心功能分级为Ⅳ级、Pitt评分≥2分及治疗2周后高NEUT、ESR和Gal-3水平是IE患者预后不良的独立危险因素(均P<0.05)。治疗2周后NEUT、ESR和Gal-3水平及三者联合预测IE患者预后不良的曲线下面积(AUC)分别为0.912、0.949、0.905和0.985。结论NEUT、ESR、Gal-3水平在IE患者中具有重要的临床预测价值。高水平的NEUT、ESR和Gal-3与IE患者的不良预后密切相关,可以作为独立的不良预后风险因素,能够为临床提供更精准的风险评估和治疗决策支持。

输尿管结石伴感染患者不同手术治疗时机的选择及作用分析

分析体外冲击波碎石(extracorporeal shock wave lithotripsy,ESWL)治疗无效的输尿管结石伴感染患者不同手术治疗时机的选择及其具体作用。选取2021年1月—2023年6月贵州省瓮安县人民医院经ESWL治疗无效的82例输尿管结石伴感染患者为研究对象,将患者按照不同手术治疗时机以及患者病情进行分组,分为两组,每组各41例。观察组患者在ESWL治疗无效后立即行逆行经尿道输尿管镜碎石取石术(ureteroscopic lithotripsy,URL)治疗,对照组患者在ESWL治疗无效后7天行URL治疗,比较两组患者治疗效果。结果显示,观察组患者治疗总有效率和结石清除率高于对照组(P<0.05),并发症总发生率低于对照组(P<0.05);术后,观察组患者IPSS评分低于对照组(P<0.05),血清学指标和生活质量评分优于对照组(P<0.05);观察组患者临床症状消失时间短于对照组(P<0.05)。研究发现,对ESWL治疗无效的输尿管结石伴感染患者立即行URL治疗,可提高结石清除率,减少术后并发症,改善患者前列腺症状和生活质量,缩短患者临床症状消失时间,优化患者血清学指标。