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Protective and Regenerative Efficacy of a Plant Oil-Based Day and Night Cream: Investigated by a Novel Approach to Reveal the Impact of Blue Light Irradiation on Epidermal Barrier Integrity and Lipid Matrix
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作者 Dorothee Dähnhardt Stephan Dähnhardt-Pfeiffer +4 位作者 Isabel Simon Dana Ditgen Inge Holland Dörte Segger Peter Staib 《Journal of Cosmetics, Dermatological Sciences and Applications》 2024年第3期227-241,共15页
In recent years, the harmful effects of blue light (400 - 500 nm) as a component of visible light (400 - 700 nm) have increasingly gained attention of science, industry, and consumers. To date, only a few in vivo test... In recent years, the harmful effects of blue light (400 - 500 nm) as a component of visible light (400 - 700 nm) have increasingly gained attention of science, industry, and consumers. To date, only a few in vivo test methods for measuring the effects of blue light on the skin have been described. A direct measurement method that can detect the immediate effects of blue light on the epidermal permeability barrier (EPB) is still lacking. In this study, we present a new methodological approach that can be used to investigate both the protective and regenerative effects of cosmetic products on the EPB after blue light irradiation. In a study with 14 female volunteers, it was investigated whether the regular application of an O/W emulsion (day cream) can strengthen and protect the epidermal barrier against damaging blue light radiation of 60 J/cm2 (protective study design) and also whether a disruption of the epidermal barrier caused by blue light radiation is restored faster and better by the regular application of another O/W emulsion (night cream) than in product-untreated skin (regenerative study design). The two O/W emulsions are different in plant oil, active ingredient composition and texture. The seven-day treatment with the day cream initially led to a significant increase in the normalized lipid lamellae length in the intercellular space, whereas the irradiation with blue light after 24 hours led to a significant decrease in the lipid lamellae length in the untreated test area, but not in the area previously treated with the product. Regarding the regenerative study design, a two-day treatment with the night cream was able to restore a blue-light-induced decrease in lipid lamellae length in the intercellular space. In summary, with the study designs presented here, the protective and regenerative effect of two cosmetic products could be demonstrated for the first time on the integrity of the EPB after blue light irradiation and the data showed that the Lipbarvis® method is suitable for investigating the damaging effects of blue light on the EPB in vivo. 展开更多
关键词 Skin Care Blue light Irradiation Skin barrier Intercellular Lipid Lamellae Electron Microscopy
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Formation and Gas Barrier Characteristics of Polysilazane-Derived Silica Coatings Formed by Excimer Light Irradiation on PET Films with Vacuum Evaporated Silica Coatings 被引量:1
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作者 Tomoji Ohishi Yoshimi Yamazaki 《Materials Sciences and Applications》 2017年第1期1-14,共14页
The effects of excimer light irradiation on polysilazane coatings formed on PET films with vacuum-evaporated SiO2 coatings and the effects of these coatings on gas barrier characteristics have been investigated. The t... The effects of excimer light irradiation on polysilazane coatings formed on PET films with vacuum-evaporated SiO2 coatings and the effects of these coatings on gas barrier characteristics have been investigated. The temperature during light irradiation has a large effect on the coating’s molecular structure and gas barrier characteristics. When irradiation was performed at 100℃, the polysilazane coating transformed into a silica coating, and a compact silica coating at a much lower temperature than with heat treatment alone was produced. Surface irregularities in the vapor-deposited silica coating were smoothed out by the formation of a polysilazane coating, which was transformed into a compact silica coating when irradiated with light, resulting in a significant improvement in the gas barrier characteristics. The water vapor permeability of the thin coating irradiated with excimer light at 100℃ showed only 0.04 g/m2&bull;day (40℃, 90% RH). According to the results of investigation of temperature variation of water-vapor permeability, it is inferred that the developed film has an excellent gas barrier value, namely, 4.90 × 10–4 g/m2&bull;day at 25℃. This gas barrier coated PET film is transparent and flexible, and can be used in the fabrication of flexible electronics. Also, the proposed fabrication method effectively provides a simple low-cost and low-temperature fabrication technique without the need for high vacuum facility. 展开更多
关键词 POLYSILAZANE Photo-Irradiation EXCIMER light Gas barrier CHARACTERISTICS PET Film Flexible Electronics
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Improved carrier injection and confinement in InGaN light-emitting diodes containing GaN/AlGaN/GaN triangular barriers 被引量:2
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作者 Li-Wen Cheng Jian Ma +9 位作者 Chang-Rui Cao Zuo-Zheng Xu Tian Lan Jin-Peng Yang Hai-Tao Chen Hong-Yan Yu Shu-Dong Wul Shun Yao Xiang-Hua Zeng Zai-Quan Xu 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第8期48-52,共5页
In this study, an InGaN lighting-emitting diode (LED) containing GaN/A1GaN/GaN triangular barriers is proposed and investigated numerically. The simulation results of output performance, carrier concentration, and r... In this study, an InGaN lighting-emitting diode (LED) containing GaN/A1GaN/GaN triangular barriers is proposed and investigated numerically. The simulation results of output performance, carrier concentration, and radiative recombination rate indicate that the proposed LED has a higher output power and an internal quantum efficiency, and a lower efficiency droop than the LED containing conventional GaN or A1GaN barriers. These improvements mainly arise from the modified energy bands, which is evidenced by analyzing the LED energy band diagram and electrostatic field near the active region. The modified energy bands effectively improve carrier injection and confinement, which significantly reduces electron leakage and increases the rate of radiative recombination in the quantum wells. 展开更多
关键词 lighting-emitting diode gallium nitride efficiency droop triangular barrier
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Efficiency enhancement of an InGaN light-emitting diode with a p-AlGaN/GaN superlattice last quantum barrier 被引量:1
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作者 熊建勇 赵芳 +6 位作者 范广涵 许毅钦 刘小平 宋晶晶 丁彬彬 张涛 郑树文 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第11期656-660,共5页
In this study, the efficiency droop of an InGaN light-emitting diode (LED) is reduced slgnlncanUy oy using a p-AlGaN/GaN superlattice last quantum barrier. The reduction in efficiency droop is mainly caused by the d... In this study, the efficiency droop of an InGaN light-emitting diode (LED) is reduced slgnlncanUy oy using a p-AlGaN/GaN superlattice last quantum barrier. The reduction in efficiency droop is mainly caused by the decrease of electron current leakage and the increase of hole injection efficiency, which is revealed by investigating the light currents, internal quantum efficiencies, energy band diagrams, carrier concentrations, carrier current densities, and radiative recombination efficiencies of three LED structures with the advanced physical model of semiconductor device (APSYS). 展开更多
关键词 light-emitting diodes p-AlGaN/GaN superlattice last quantum barrier efficiency droop
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Improvement of the carrier distribution with GaN/InGa N/AlGaN/InGaN/GaN composition-graded barrier for InGaN-based blue light-emitting diode 被引量:1
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作者 Min Guo Zhi-You Guo +2 位作者 Jing Huang Yang Liu Shun-Yu Yao 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第2期499-504,共6页
In Ga N light-emitting diodes(LEDs) with Ga N/In Ga N/Al Ga N/In Ga N/Ga N composition-graded barriers are proposed to replace the sixth and the middle five Ga N barriers under the condition of removing the electron... In Ga N light-emitting diodes(LEDs) with Ga N/In Ga N/Al Ga N/In Ga N/Ga N composition-graded barriers are proposed to replace the sixth and the middle five Ga N barriers under the condition of removing the electron blocking layer(EBL)and studied numerically in this paper. Simulation results show that the specially designed barrier in the sixth barrier is able to modulate the distributions of the holes and electrons in quantum well which is adjacent to the specially designed barrier. Concretely speaking, the new barrier could enhance both the electron and hole concentration remarkably in the previous well and reduce the hole concentration for the latter one to some extent along the growth direction. What is more,a phenomenon, i.e., a better carrier distribution in all the wells, just appears with the adoption of the new barriers in the middle five barriers, resulting in a much higher light output power and a lower efficiency droop than those in a conventional LED structure. 展开更多
关键词 composition-graded barriers light-emitting diodes carrier distribution
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Improved efficiency droop characteristics in an InGaN/GaN light-emitting diode with a novel designed last barrier structure
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作者 王天虎 徐进良 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第12期550-555,共6页
In this study, the characteristics of nitride-based light-emitting diodes with different last barrier structures are analysed numerically. The energy band diagrams, electrostatic field near the last quantum barrier, c... In this study, the characteristics of nitride-based light-emitting diodes with different last barrier structures are analysed numerically. The energy band diagrams, electrostatic field near the last quantum barrier, carrier concentration in the quantum well, internal quantum efficiency, and light output power are systematically investigated. The simulation results show that the efficiency droop is markedly improved and the output power is greatly enhanced when the conventional GaN last barrier is replaced by an AlGaN barrier with Al composition graded linearly from 0 to 15% in the growth direction. These improvements are attributed to enhanced efficiencies of electron confinement and hole injection caused by the lower polarization effect at the last-barrier/electron blocking layer interface when the graded Al composition last barrier is used. 展开更多
关键词 light-emitting diodes internal quantum efficiency efficiency droop last barrier
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Droop improvement in blue InGaN light-emitting diodes with GaN/InGaN superlattice barriers
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作者 童金辉 赵璧君 +7 位作者 王幸福 陈鑫 任志伟 李丹伟 卓祥景 章俊 易翰翔 李述体 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第6期651-655,共5页
GaN/InGaN superlattice barriers are used in InGaN-based light-emitting diodes (LEDs). The electrostatic field in the quantum wells, electron hole wavefunction overlap, carrier concentration, spontaneous emission spe... GaN/InGaN superlattice barriers are used in InGaN-based light-emitting diodes (LEDs). The electrostatic field in the quantum wells, electron hole wavefunction overlap, carrier concentration, spontaneous emission spectrum, light-current performance curve, and internal quantum efficiency are numerically investigated using the APSYS simulation software. It is found that the structure with GaN/InGaN superlattice barriers shows improved light output power, and lower current leakage and efficiency droop. According to our numerical simulation and analysis, these improvements in the electrical and optical characteristics are mainly attributed to the alleviation of the electrostatic field in the active region. 展开更多
关键词 GaN-based light-emitting diodes GaN/InGaN superlattice barriers electrostatic field
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Efficiency enhancement of InGaN based blue light emitting diodes with InGaN/GaN multilayer barriers
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作者 童金辉 李述体 +6 位作者 卢太平 刘超 王海龙 仵乐娟 赵璧君 王幸福 陈鑫 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第11期528-532,共5页
The advantages of InGaN based light-emitting diodes with InGaN/GaN multilayer barriers are studied. It is found that the structure with InGaN/GaN multilayer barriers shows improved light output power, lower current le... The advantages of InGaN based light-emitting diodes with InGaN/GaN multilayer barriers are studied. It is found that the structure with InGaN/GaN multilayer barriers shows improved light output power, lower current leakage, and less efficiency droop over its conventional InGaN/GaN counterparts. Based on the numerical simulation and analysis, these improvements on the electrical and the optical characteristics are mainly attributed to the alleviation of the electrostatic field in the quantum wells (QWs) when the InGaN/GaN multilayer barriers are used. 展开更多
关键词 GaN based light-emitting diode InGaN/GaN multilayer barriers electrostatic field
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Space Flight, Astronautics and Light Barrier
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作者 SongJian 《工程科学(英文版)》 2005年第2期1-9,共9页
Amazing achievements and accomplishments of space science and technologies in the past half-century have profoundly affected all disciplines of natural science and engineering. By the end of 20(th) Century, man or man... Amazing achievements and accomplishments of space science and technologies in the past half-century have profoundly affected all disciplines of natural science and engineering. By the end of 20(th) Century, man or man-made spacecrafts landed, or approached and surveyed all planets of solar system and their moons except Pluto. Biologists believe that life may emerge and evolve wherever liquid water exists. No liquid water is ever found yet on all planets and their moons in Solar System except for our Earth. Our mother planet turned out to be the only life-supporting oasis within 4 light years of the Milky Way. It is suggested in this article that time has come for science and engineering communities to study and prepare interstellar flight of manned or unmanned spacecrafts beyond Solar System. Four issues are to be addressed as prerequisite for such flight, namely, detailed survey of nearby space beyond Solar System, design of nuclear fusion rocket engine, long-sustainable on-board life-supporting system and breakthrough of the light barrier. 展开更多
关键词 空间探测 航天学 光栅 星际飞行
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强脉冲光联合类人胶原蛋白敷料治疗面部色素沉着的疗效及相关测评指标变化评析
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作者 马云鹏 王艳玲 +1 位作者 李艳 韩朋 《中国美容医学》 CAS 2024年第10期54-57,共4页
目的:探究强脉冲光联合类人胶原蛋白敷料治疗面部色素沉着的疗效以及对VISIA系统色素沉着评分和表皮油脂量、TEWL的影响。方法:选取从2021年1月-2022年6月在笔者医院收治的100例女性面部色素沉着患者,将所有患者按随机数字表法分配为对... 目的:探究强脉冲光联合类人胶原蛋白敷料治疗面部色素沉着的疗效以及对VISIA系统色素沉着评分和表皮油脂量、TEWL的影响。方法:选取从2021年1月-2022年6月在笔者医院收治的100例女性面部色素沉着患者,将所有患者按随机数字表法分配为对照组(n=50)、观察组(n=50),对照组使用强脉冲光治疗,观察组在对照组的基础上联合类人胶原蛋白敷料治疗;比较两组患者的疗效、VISIA系统色素沉着评分、皮肤屏障功能:包括表皮含水量、表皮油脂含量和经皮水分丢失量(TEWL)、SAS、DLQI评分的变化情况和不良反应的发生情况。结果:观察组患者治疗后总有效率(88.00%,44/50)高于对照组(P<0.05);与治疗前相比,治疗后观察组和对照组的VISIA系统色素沉着评分、TEWL、SAS、DLQI评分显著降低,表皮含水量、表皮油脂含量显著升高(P<0.05),治疗后与对照组相比,观察组的VISIA系统色素沉着评分、TEWL、SAS、DLQI评分显著降低,表皮含水量、表皮油脂含量显著升高(P<0.05);不良反应发生率,观察组和对照组比较,差异无统计学意义(P>0.05)。结论:强脉冲光联合类人胶原蛋白敷料治疗面部色素沉着的效果显著,可以促进色素沉着消退,改善皮肤屏障功能,改善患者生活质量和心理状态,且安全性较高。 展开更多
关键词 强脉冲光 类人胶原蛋白敷料 经皮水分丢失量 色素沉着 皮肤屏障功能
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DPL联合注射用透明质酸钠复合溶液在面部年轻化治疗中的应用 被引量:1
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作者 常晓丹 王玲艳 +3 位作者 郭独一 李芬芬 张佳钰 潘靖 《中国美容医学》 CAS 2024年第2期77-81,共5页
目的:探究精准脉冲光(Delicate pulse light,DPL)联合注射用透明质酸钠复合溶液改善面部年轻化的应用效果。方法:纳入2022年7月-2023年1月在北京积水潭医院皮肤科门诊就诊的女性就医者60例,随机分为对照组(予以DPL治疗,n=30)和观察组(予... 目的:探究精准脉冲光(Delicate pulse light,DPL)联合注射用透明质酸钠复合溶液改善面部年轻化的应用效果。方法:纳入2022年7月-2023年1月在北京积水潭医院皮肤科门诊就诊的女性就医者60例,随机分为对照组(予以DPL治疗,n=30)和观察组(予以DPL联合透明质酸钠复合溶液注射治疗,n=30)。连续治疗3个月,比较两组治疗前后面部肤质、皮肤屏障功能改善情况以及治疗中不良反应发生情况。结果:治疗后,两组就医者表面色素、红区、皱纹、毛孔、紫外线色斑、卟啉、棕色斑数据均下降,且观察组低于对照组(P<0.05)。治疗后,两组皮肤含水量、油脂含量均上升,且观察组高于对照组(P<0.05),两组表皮水分丢失量(Trans epidermal water loss,TEWL)均下降,且观察组低于对照组(P<0.05)。治疗后,观察组总有效率为100.00%,高于对照组的86.67%(P<0.05)。观察组不良反应总发生率为23.33%,高于对照组的13.33%,差异无统计学意义(P>0.05)。结论:DPL联合透明质酸钠复合溶液注射治疗用于面部年轻化治疗中可改善面部肤质情况,增强皮肤屏障功能,具有较高的疗效,且安全性较高。 展开更多
关键词 精准脉冲光 注射用透明质酸钠 面部年轻化 皮肤屏障功能
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Al组分阶梯型渐变电子阻挡层深紫外LED性能研究
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作者 陈颖 黄丽莹 +2 位作者 张悦 冯镜如 钟伟 《赣南师范大学学报》 2024年第3期85-89,共5页
为减少电子泄漏改善发光性能,本文基于深紫外发光二极管(LED)提出了一种Al组分阶梯型渐变电子阻挡层(EBL)结构.通过数值研究,对比分析了不同EBL结构对深紫外LED发光性能的影响规律.结果表明,相较于传统EBL结构的深紫外LED(样品A),Al组... 为减少电子泄漏改善发光性能,本文基于深紫外发光二极管(LED)提出了一种Al组分阶梯型渐变电子阻挡层(EBL)结构.通过数值研究,对比分析了不同EBL结构对深紫外LED发光性能的影响规律.结果表明,相较于传统EBL结构的深紫外LED(样品A),Al组分阶梯型渐变EBL结构的深紫外LED(样品B、样品C)最大内量子效率(IQE)分别提高了7.9%、14.2%,光输出功率(LOP)在200 mA下分别提升了73.3%、80.1%.这是因为Al组分阶梯型渐变EBL结构有效改善了EBL处极化效应引起的电场强度,进而减少了电子泄漏. 展开更多
关键词 深紫外LED 极化效应 电子泄漏 电子阻挡层 光输出功率
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不同线宽电流阻挡层的GaN基LED芯片光电特性研究
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作者 田媛 刘叶锋 +2 位作者 陈晓冰 王忠东 闫晓密 《传感器与微系统》 CSCD 北大核心 2024年第10期38-41,共4页
发光二极管(LED)由于具有低功耗、小体积、宽光谱范围等优点,被广泛应用于可见光通信、光电医疗、快速无损检测等微系统领域。为了进一步提高LED的发光效率,在图形化蓝宝石衬底上制备了具有不同线宽电流阻挡层(CBL)的氮化镓(GaN)基LED,... 发光二极管(LED)由于具有低功耗、小体积、宽光谱范围等优点,被广泛应用于可见光通信、光电医疗、快速无损检测等微系统领域。为了进一步提高LED的发光效率,在图形化蓝宝石衬底上制备了具有不同线宽电流阻挡层(CBL)的氮化镓(GaN)基LED,并研究其光电特性。结果表明,在120mA测试电流作用下,由于CBL的插入增大了有源层有效光发射区域的电流密度,减少了p电极(p-pad)下的寄生光吸收,LED芯片的辐射功率与光电转换效率随着CBL线宽的增加而单调增加,在CBL线宽设计为13μm时,辐射功率与光电转换效率达到最大;正向电压(VF)随着CBL线宽的增加略有增加,表明绝缘的CBL层增大串联电阻。本文为CBL线宽的选择提供了新思路,可有效提高LED的发光效率。 展开更多
关键词 发光二极管 电流阻挡层 氮化镓 发光效率
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超晶格电子阻挡层周期数对AlGaN基深紫外发光二极管性能的影响
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作者 刘举 曹一伟 +4 位作者 吕全江 杨天鹏 米亭亭 王小文 刘军林 《物理学报》 SCIE EI CAS CSCD 北大核心 2024年第12期393-401,共9页
在AlGaN基深紫外发光二极管(DUV-LEDs)中设计了具有不同周期数的超晶格电子阻挡层(SL-EBL)结构,研究了SL-EBL周期数对DUV-LEDs发光效率、I-V特性、可靠性及有源区载流子复合机制的影响.研究结果表明,随着SL-EBL的周期数增加,DUV-LEDs的... 在AlGaN基深紫外发光二极管(DUV-LEDs)中设计了具有不同周期数的超晶格电子阻挡层(SL-EBL)结构,研究了SL-EBL周期数对DUV-LEDs发光效率、I-V特性、可靠性及有源区载流子复合机制的影响.研究结果表明,随着SL-EBL的周期数增加,DUV-LEDs的光输出功率(LOP)、外量子效率(EQE)和电光转换效率(WPE)均呈先上升后下降的趋势,同时泄漏电流减小,可靠性提升.当周期数为7时(厚度为28 nm),DUV-LEDs裸芯的EQE和WPE均达到最大值,在7.5 mA注入电流下分别为3.5%和3.2%.能带模拟结果证明了增加SL-EBL周期数可以有效提升电子势垒高度,而几乎不改变空穴势垒高度.然而,当SL-EBL超过一定厚度时,抑制了空穴向有源区的注入,导致EQE和WPE随SL-EBL周期数变化出现拐点.研究了SL-EBL周期数对DUV-LEDs载流子复合机制的影响,发现增加SL-EBL周期数可以有效地降低有源区内载流子非辐射复合. 展开更多
关键词 深紫外发光二极管 电子阻挡层 可靠性 外量子效率
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强脉冲光联合红黄光治疗面部敏感性皮肤的疗效及对皮肤屏障功能的影响
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作者 王瑞丽 李姗姗 +1 位作者 王晓云 王丽 《中国美容医学》 CAS 2024年第11期44-48,共5页
目的:探讨强脉冲光联合红黄光对面部敏感性皮肤改善效果及对皮肤屏障的修复作用。方法:选取医院2022年1月-2023年1月收治的80例面部敏感性皮肤患者作为研究对象。将80例患者随机化分为对照组(n=40)和观察组(n=40)。对照组采用强脉冲光治... 目的:探讨强脉冲光联合红黄光对面部敏感性皮肤改善效果及对皮肤屏障的修复作用。方法:选取医院2022年1月-2023年1月收治的80例面部敏感性皮肤患者作为研究对象。将80例患者随机化分为对照组(n=40)和观察组(n=40)。对照组采用强脉冲光治疗,观察组采用强脉冲光联合红黄光治疗,比较两组患者干预前、干预后4周皮肤敏感指数、皮肤屏障功能、皮肤状态参数、疗效及治疗过程中的不良反应。结果:较干预前,干预后4周两组患者皮肤敏感指数均有下降(P<0.05),且观察组相较于对照组更低(P<0.05)。较干预前,干预后4周两组患者皮肤经皮水分散失值(TEWL)指数、pH值均降低(P<0.05),且观察组相较于对照组更低(P<0.05)。较干预前,干预后4周两组患者红斑面积、红斑参数、凹陷指数各项参数值均降低(P<0.05),且观察组相较于对照组更低(P<0.05)。干预后4周,观察组患者总疗效高于对照组(P<0.05)。治疗过程中两组患者的不良反应相比较无统计学意义(P>0.05)。结论:相比于单独应用强脉冲光治疗,应用强脉冲光联合红黄光治疗,对于面部敏感性皮肤患者而言,更有利于缓解皮肤敏感指数、增强皮肤屏障功能、改善皮肤状态、疗效更显著且不会增加不良反应,安全性较高,适合在临床推广使用。 展开更多
关键词 强脉冲光 红黄光 面部 敏感性皮肤 皮肤屏障 皮肤敏感指数
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通过诱导载流子的V坑传输提升GaN基绿光LED的空穴注入效率
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作者 张东皓 杨东锴 +2 位作者 徐畅 刘信佑 包立君 《发光学报》 EI CAS CSCD 北大核心 2024年第5期800-808,共9页
为了提升GaN基多量子阱LED的空穴注入效率,设计了具有不同最后势垒层结构的GaN基多量子阱外延结构,并将其制备为绿光mini-LED发光芯片,利用低温电致发光光谱、电流电压特性测试对其载流子传输机制进行了研究。结果表明,在采用AlGaN或GaN... 为了提升GaN基多量子阱LED的空穴注入效率,设计了具有不同最后势垒层结构的GaN基多量子阱外延结构,并将其制备为绿光mini-LED发光芯片,利用低温电致发光光谱、电流电压特性测试对其载流子传输机制进行了研究。结果表明,在采用AlGaN或GaN/AlN最后势垒层的样品中,有更多载流子可以传输到深层量子阱,空穴注入效率获得提升。本文对这一现象中的载流子运输机制以及V坑缺陷在其中所起的作用进行了研究,发现这种提升主要来自空穴V坑注入比例的增大。实验还发现,过大的V坑注入比例也会造成非辐射复合率上升,从而抑制了AlGaN最后势垒层样品的电光转换效率。 展开更多
关键词 发光二极管 最后势垒层 空穴注入 INGAN/GAN多量子阱 V坑
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荆防方加减联合红黄光及rb-bFGF凝胶治疗面部糖皮质激素依赖性皮炎疗效分析
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作者 张义 赵树梅 +2 位作者 刘欢 丁言旭 徐莉 《中国美容医学》 CAS 2024年第8期88-91,共4页
目的:探讨荆防方加减联合红黄光及重组牛碱性成纤维细胞生长因子(rb-bFGF)凝胶治疗面部糖皮质激素依赖性皮炎(Facial corticosteroid addictive dermatitis,FCAD)的效果。方法:根据治疗方法不同将2022年2月-2023年8月笔者医院的90例FCA... 目的:探讨荆防方加减联合红黄光及重组牛碱性成纤维细胞生长因子(rb-bFGF)凝胶治疗面部糖皮质激素依赖性皮炎(Facial corticosteroid addictive dermatitis,FCAD)的效果。方法:根据治疗方法不同将2022年2月-2023年8月笔者医院的90例FCAD患者分为对照组和观察组,各45例。对照组使用红黄光照射治疗,观察组同时使用荆防方治疗。对比两组的临床疗效、症状评分、皮肤屏障功能、血清炎症因子水平、不良反应。结果:观察组的有效率(91.11%)高于对照组(73.33%)(P<0.05),观察组治疗后潮红、瘙痒、干燥脱屑、灼热疼痛的症状评分均低于对照组(P<0.05),观察组治疗后的皮脂含量、皮肤角质层含水量(Cuticle water conten,WCSC)高于对照组,经皮肤水分流失量(Transcutaneous water loss,TEWL)低于对照组(P<0.05),观察组治疗后的干扰素-γ(INF-γ)、免疫球蛋白-E(IgE)、白细胞介素-4(IL-4)水平均低于对照组(P<0.05),两组不良反应比较,差异无统计学意义(P>0.05)。结论:荆防方加减联合红黄光及rb-bFGF凝胶治疗FCAD的效果显著,能够减轻患者的症状,提高皮肤屏障功能,改善炎症状态。 展开更多
关键词 荆防方 LED红光 LED黄光 面部糖皮质激素依赖性皮炎 皮肤屏障功能
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背界面纳米光子结构提高透明导电氧化物基超薄Cu(In, Ga)Se_(2)太阳能电池电学性能的理论探究
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作者 李航瑜 宋浩 +2 位作者 涂野 裴寒宁 殷官超 《硅酸盐通报》 CAS 北大核心 2024年第8期3063-3070,3088,共9页
透明导电氧化物(TCO)基超薄Cu(In, Ga)Se_(2)(CIGSe)太阳能电池具有建筑光伏一体化的潜力,然而由于背肖特基结的存在,其增大背复合速率S_b在提高空穴传输的同时也增加了光生电子背复合,从而抑制了其性能的提高。本文使用1D-SCAPS软件对... 透明导电氧化物(TCO)基超薄Cu(In, Ga)Se_(2)(CIGSe)太阳能电池具有建筑光伏一体化的潜力,然而由于背肖特基结的存在,其增大背复合速率S_b在提高空穴传输的同时也增加了光生电子背复合,从而抑制了其性能的提高。本文使用1D-SCAPS软件对背界面纳米光子结构(NPs)如何提高电池的性能进行理论探究,结果表明,背界面NPs的引入产生了复杂的电学效应。一方面,NPs本身不吸收光能,从而降低了背界面附近的有效光吸收体积,导致背界面光生载流子浓度降低,光生电子的背复合显著降低;另一方面,NPs的引入增加了吸收层厚度,导致空间电荷区(SCR)远离背界面,降低了其对光生电子的收集效率,增加了背复合。在高背复合速率(S_(b)=1.0×10^(7)cm·s^(-1))下,光生载流子浓度降低产生的背复合降低大于SCR移动产生的背复合增加,因此总体的背复合降低。与此同时,背复合的降低还缓解了高S_b时的光生电子损耗,从而解除了随S_b增大而增加的背复合对电池性能的抑制。这些发现为设计和优化TCO基超薄CIGSe太阳能电池提供了参考。 展开更多
关键词 TCO基超薄CIGSe太阳能电池 纳米光子结构 肖特基势垒 光捕获 背复合 透明导电氧化物
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强脉冲光联合重组贻贝粘蛋白水凝胶敷料治疗面部激素依赖性皮炎的疗效及对皮肤屏障功能指标的影响分析
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作者 姜海娟 佟欣 《中国实用医药》 2024年第16期70-73,共4页
目的观察强脉冲光联合重组贻贝粘蛋白水凝胶敷料治疗面部激素依赖性皮炎患者的临床疗效及对皮肤屏障功能的影响。方法纳入72例面部激素依赖性皮炎患者作为观察对象,随机分为观察组(37例)和对照组(35例)。观察组使用强脉冲光联合重组贻... 目的观察强脉冲光联合重组贻贝粘蛋白水凝胶敷料治疗面部激素依赖性皮炎患者的临床疗效及对皮肤屏障功能的影响。方法纳入72例面部激素依赖性皮炎患者作为观察对象,随机分为观察组(37例)和对照组(35例)。观察组使用强脉冲光联合重组贻贝粘蛋白水凝胶敷料治疗,对照组使用强脉冲光治疗。比较两组患者皮肤屏障功能(皮肤油脂含量、皮肤含水量、经表皮水分丢失量),面部自觉症状和面部客观体征评分,临床疗效和安全性。结果治疗后,两组患者皮肤油脂含量、皮肤含水量、经表皮水分丢失量较治疗前明显改善,且观察组患者皮肤油脂含量(115.53±9.23)μg/cm^(2)和皮肤含水量(35.55±4.48)%较对照组患者的(102.77±8.26)μg/cm^(2)、(28.85±3.76)%更高,经表皮水分丢失量(13.82±2.29)g/(cm^(2)·h)较对照组患者的(17.78±3.57)g/(cm^(2)·h)更低,差异有统计学意义(P<0.05)。治疗后,两组患者的面部自觉症状评分和面部客观体征评分较治疗前显著降低,且观察组患者面部自觉症状评分(1.02±0.30)分和面部客观体征评分(3.10±1.15)分较对照组患者的(4.45±1.11)、(7.89±1.22)分更低,差异有统计学意义(P<0.05)。治疗后,观察组患者的痊愈率48.65%、总有效率91.89%均较对照组患者的22.86%、71.43%更高,差异有统计学意义(P<0.05)。观察组患者的不良事件发生率5.41%较对照组患者的22.86%更低,差异有统计学意义(P<0.05)。结论强脉冲光联合重组贻贝粘蛋白水凝胶敷料可有效改善面部激素依赖性皮炎患者临床症状,对皮肤屏障功能指标具有改善作用,安全有效,值得临床推广使用。 展开更多
关键词 重组贻贝粘蛋白水凝胶敷料 强脉冲光 面部激素依赖性皮炎 皮肤屏障功能
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强脉冲光联合Q开关1064 nm Nd:YAG激光治疗黄褐斑的临床观察
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作者 施华兰 黄旻华 邓园 《中国医疗美容》 2024年第7期12-15,共4页
目的探究强脉冲光与Q开关1064 nm Nd:YAG激光联合治疗黄褐斑的治疗效果。方法选取2022年8月至2023年8月苏州市吴中人民医院收治的120例黄褐斑患者,依据治疗方式不同分为强脉冲光组(n=38)、Q开关1064 nm Nd:YAG激光组(n=41)与联合治疗组(... 目的探究强脉冲光与Q开关1064 nm Nd:YAG激光联合治疗黄褐斑的治疗效果。方法选取2022年8月至2023年8月苏州市吴中人民医院收治的120例黄褐斑患者,依据治疗方式不同分为强脉冲光组(n=38)、Q开关1064 nm Nd:YAG激光组(n=41)与联合治疗组(n=41),参考黄褐斑面积与严重指数评分评估疗效,对比治疗前后激光扫描共聚焦显微镜图像特征及皮肤屏障指标。结果联合治疗组治疗总有效率(97.56%)高于强脉冲光组(84.21%)与Q开关1064 nm Nd:YAG激光组(80.49%),差异有统计学意义(P<0.05);治疗后联合治疗组表皮颗粒层含量、棘层含量、基底层色素颗粒层含量、TEWL显著低于强脉冲光组与Q开关1064 nm Nd:YAG激光组,角质层含水量、皮脂含量高于强脉冲光组与Q开关1064 nm Nd:YAG激光组,上述结果差异均有统计学意义(P<0.05)。结论强脉冲光与Q开关1064 nm Nd:YAG激光联合治疗黄褐斑疗效显著高于单一治疗,可改善皮肤屏障功能,临床应用价值较高,值得借鉴。 展开更多
关键词 黄褐斑 强脉冲光 Q开关1064 nm Nd:YAG激光 皮肤屏障
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