Objective The present study aimed to investigate the association of red meat usual intake with metabolic syndrome(Met S),and explore the contribution of red meat usual intake to serum ferritin.Methods Based on the dat...Objective The present study aimed to investigate the association of red meat usual intake with metabolic syndrome(Met S),and explore the contribution of red meat usual intake to serum ferritin.Methods Based on the data from the longitudinal China Health and Nutrition Survey(CHNS),2,797 healthy adults aged 18–75 years without hypertension,diabetes,and Met S were selected in 2009 as subjects and follow-up studies were carried out till 2015.We used the National Cancer Institute(NCI)method to estimate the usual intake of foods.Multivariable logistic regressions were performed to evaluate the association between red meat usual intake and the risk of Met S.Quantile regression analysis was used to study the relationship between red meat consumption and serum ferritin levels.Results After adjusting for potential confounders,red meat,and fresh red meat were positively associated with the risk of Met S(RR=1.41,95%CI:1.05–1.90 and RR=1.37,95%CI:1.02–1.85,respectively).These relationships showed increasing trend(P<0.05).The level of serum ferritin increased significantly with the number of Met S components(P<0.05).The quantile regression analysis showed that red meat and fresh red meat usual intake had a significant positive association with serum ferritin levels across the entire conditional serum ferritin distribution(P<0.05).Processed red meat did not exhibit a similar association.Conclusion Higher red meat usual intake was associated with an increased risk of Met S and elevated serum ferritin levels.展开更多
Background： In Padova and Vienna International Classification, the usual intestinal metaplasia （UIM） of the stomach, including complete and incomplete type, is defined as negative for dysplasia, and hyperproliferat...Background： In Padova and Vienna International Classification, the usual intestinal metaplasia （UIM） of the stomach, including complete and incomplete type, is defined as negative for dysplasia, and hyperproliferative intestinal metaplasia （HIM） as indefinite for dysplasia, but the biological characteristics of these two types of intestinal metaplasia （IM）remain to be studied. Objective： To investigate the biological differences between UIM, HIM and intestinal type gastric cancer （IGC）, a panel of biomarkers were detected. Methods： A total of 38 cases of IGC, 41 HIM and 56 UIM adjacent to gastric cancer were studied. Immunohistochemistry was used to detect the expressions of pS2, MUC2, MUC5AC, MUC6, Ki-67, EGFR, p53 and sulfo-Lewisa in UIM, HIM and IGC. Microsatellite instability （MSI） in UIM, HIM and IGC was detected by using Denaturing High Performance Liquid Chromatography （DHPLC）. Results： The pS2 antigen expression in UIM （78.6%） was significantly higher than in HIM and IGC （9.8%, 10.5%）, p〈0.01. The MUC6, sulfo-Lewisa and EGFR protein expressions were significant increased in HIM （24.4%, 82.9%, 48.7%） and IGC （34.2%, 75.0%, 42.1%） than in UIM （3.6%, 25.5%, 17.9%）, p〈0.01. A reversed pattern of expressions of MUC2 and MUC5AC was observed in UIM （96.4%, 50.0%） and HIM （82.9%, 36.6%） compared with IGC （52.6%, 13.2%）, p〈0.05; and the p53 gene expression was increased from UIM （1.8%） to HIM （19.5%） to IGC （57.9%）, p〈0.01. The Ki-67 labeling index was significantiy different among three lesions （UIM： 16%±6%, HIM： 45%±9%, IGC： 63%±10%, p〈0.01）. Conclusion： These findings suggest that there are different bio-characteristics among UIM, HIM and IGC, and HIM may have higher potential to progress to more advanced lesions in comparison with UIM.展开更多
It is shown that evolution characteristics of black hole(BH)parameters in the pure disk-accretion are determined uniquely by BH spin parameter aa_(*).Some unusual evolution characteristics of the parameters of BH accr...It is shown that evolution characteristics of black hole(BH)parameters in the pure disk-accretion are determined uniquely by BH spin parameter aa_(*).Some unusual evolution characteristics of the parameters of BH accretion disks,such as angular velocity,temperature and event horizon radius,are investigated in both thin and thick disk-accretion.And the corresponding turning points,a_(*)^(c),are derived.In addition,two characteristic functions describing the evolution of BH parameters are derived for thin and thick disks,respectively.展开更多
The usual fermion realizations of quantum algebra S1_(q)(2) defining higher-dimensional representations are built in this letter.Using them,we construct a usual fermion system with quantum group symmetry of S1_(q)(2) ...The usual fermion realizations of quantum algebra S1_(q)(2) defining higher-dimensional representations are built in this letter.Using them,we construct a usual fermion system with quantum group symmetry of S1_(q)(2) as a q-deformation of the pairing correlation model in many-body problems.Its energy spectra are exactly solved out from the representation theory of S1_(q)(2).展开更多
We study the superfluid behavior of a population imbalanced ultracold atomic Fermi gases with a short range attractive interaction in a one-dimensional(1D)optical lattice,using a pairing fluctuation theory.We show tha...We study the superfluid behavior of a population imbalanced ultracold atomic Fermi gases with a short range attractive interaction in a one-dimensional(1D)optical lattice,using a pairing fluctuation theory.We show that,besides widespread pseudogap phenomena and intermediate temperature superfluidity,the superfluid phase is readily destroyed except in a limited region of the parameter space.We find a new mechanism for pair hopping,assisted by the excessive majority fermions,in the presence of continuum-lattice mixing,which leads to an unusual constant Bose-Einstein condensate(BEC)asymptote for Tc that is independent of pairing strength.In result,on the BEC side of unitarity,superfluidity,when it exists,may be strongly enhanced by population imbalance.展开更多
An ultra-thin Co2MnSi(0.5 nm)/Mn Ga(1.5 nm) bilayer capped with Pt(5 nm) has been successfully grown by molecular-beam epitaxy.It is a potential candidate of synthetic antiferromagnets due to antiferromagnetic couplin...An ultra-thin Co2MnSi(0.5 nm)/Mn Ga(1.5 nm) bilayer capped with Pt(5 nm) has been successfully grown by molecular-beam epitaxy.It is a potential candidate of synthetic antiferromagnets due to antiferromagnetic coupling between Co2MnSi and MnGa,which is a promising skyrmion-racetrack-memory medium without skyrmion Hall effect after capping with a Pt layer.Unusual humps in transverse Hall resistance loops are clearly observed in the temperature range from 260 to 400 K.This anomaly is generally attributed to topological Hall effect,but other than that,we prove that non-uniform rotation of magnetic moments in the bilayer with magnetic field sweeping is also a possible mechanism contributed to the unusual hump.展开更多
Business as Usual （BaU） scenario in developing countries has been a debated issue in climate change negotiations. This paper analyzes different definitions of BaU and points out that the major difference among these...Business as Usual （BaU） scenario in developing countries has been a debated issue in climate change negotiations. This paper analyzes different definitions of BaU and points out that the major difference among these definitions is how to set the starting point of BaU projections, that is the so called base year. Some international institutions use current policy scenarios to project a BaU trajectory of developing countries. Such definition will lead to an underestimation of BaU emissions of developing countries and thus an underestimation of mitigation efforts. This paper concludes with a suggestion to use a without policy scenario with a clear base year as definition of BaU. Such a definition will set an objective benchmark to assess mitigation efforts of develonin countries.展开更多
When assessing food intake patterns in groups of individuals, a major problem is finding usual intake distribution. This study aimed at searching for a probability distribution to estimate the usual intake of nutrient...When assessing food intake patterns in groups of individuals, a major problem is finding usual intake distribution. This study aimed at searching for a probability distribution to estimate the usual intake of nutrients using data from a cross-sectional investigation on nutrition students from a public university in Sao Paulo state, Brazil. Data on 119 women aged 19 to 30 years old were used. All women answered a questionnaire about their lifestyle, diet and demographics. Food intake was evaluated from a non-consecutive three-day 24-hour food record. Different probability distributions were tested for vitamins C and E, panthotenic acid, folate, zinc, copper and calcium where data normalization was not possible. Empirical comparisons were performed, and inadequacy prevalence was calculated by comparing with the NRC method. It was concluded that if a more realistic distribution for usual intake is found, results can be more accurate as compared to those achieved by other methods.展开更多
Objective： To assess whether adherence to amiodarone monitoring differed pre- and post-amiodarone restriction template and implementation of the pharmacist-managed clinic. Design： This was a retrospective chart revi...Objective： To assess whether adherence to amiodarone monitoring differed pre- and post-amiodarone restriction template and implementation of the pharmacist-managed clinic. Design： This was a retrospective chart review study. Setting： A large, academically-affiliated Veteran Affairs Healthcare System providing primary and tertiary care. Patients： 580 patients were identified as having an active prescription for amiodarone for at least 60 days from January l, 2009 to August 31, 2013 and receiving primary care at the VAAHS （Veterans Affairs Ann Arbor Healthcare System）. Results： Nearly all patients had TSH and LFTs at baseline regardless of study group. Significant associations between baseline rates for CXR, ECG, PFT, and opbthalmologic exams were found, with higher rates in the clinic and template arms compared to usual care. Similar patterns for all monitoring outcome rates were also found for both the 6- and 12-month measures. Conclusions： Patients on amiodarone who are followed by a pharmacist-managed clinic or where a restricted ordering template was used had increased compliance with amiodarone monitoring guidelines compared to usual care. Use of a restricted template may be a reasonable option in place of a pharmacist-managed service.展开更多
Dear Editor,The problem of age estimation in amphibians and reptiles with annual fluctuations of growth pattern has been considered to be mostly solved since the skeletochronological method was introduced(Kleinenberg ...Dear Editor,The problem of age estimation in amphibians and reptiles with annual fluctuations of growth pattern has been considered to be mostly solved since the skeletochronological method was introduced(Kleinenberg and Smirina,1969).This method is based on counting the number of lines of arrested growth(LAGs)—cyclical growth marks that are usually formed annually and characterized by different optical aspects within the tubular bones.展开更多
One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan,reaching zero production in 2015.In response,the country started importing more fossil energy including coal,oil,and n...One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan,reaching zero production in 2015.In response,the country started importing more fossil energy including coal,oil,and natural gas to fill the energy gap.However,this led to a significant increase in carbon emissions,hindering the efforts to reduce its carbon footprint.In the current situation,Japan is actively working to balance its energy requirements with environmental considerations,including the utilization of hydrogen fuel.Therefore,this paper aims to explore the feasibility and implications of using hydrogen power plants as a means to reduce emissions,and this analysis will be conducted using the energy modeling of the MARKAL-TIMES Japan framework.The hydrogen scenario(HS)is assumed with the extensive integration of hydrogen into the power generation sector,supported by a hydrogen import scheme.Additionally,this scenario will be compared with the Business as Usual(BAU)scenario.The results showed that the generation capacities of the BAU and HS scenarios have significantly different primary energy supplies.The BAU scenario is highly dependent on fossil fuels,while the HS scenario integrates hydrogen contribution along with an increase in renewable energy,reaching a peak contribution of 2,160 PJ in 2050.In the HS scenario,the target of reducing CO_(2) emissions by 80%is achieved through significant hydrogen penetration.By 2050,the total CO_(2) emissions are estimated to be 939 million tons for the BAU scenario and 261 million tons for the Hydrogen scenario.In addition,the contribution of hydrogen to electricity generation is expected to be 153 TWh,smaller than PV and wind power.展开更多
基金funded by the Ministry of Finance of the People’s Republic of China[No.13103110700015005]Carolina Population Center[No.P2CHD050924,T32 HD007168]+1 种基金the University of North Carolina at Chapel Hill,the NIH[No.R01-HD30880,DK056350,R24 HD050924,and R01-HD38700]the NIH Fogarty International Center[No.D43TW009077,D43 TW007709].
文摘Objective The present study aimed to investigate the association of red meat usual intake with metabolic syndrome(Met S),and explore the contribution of red meat usual intake to serum ferritin.Methods Based on the data from the longitudinal China Health and Nutrition Survey(CHNS),2,797 healthy adults aged 18–75 years without hypertension,diabetes,and Met S were selected in 2009 as subjects and follow-up studies were carried out till 2015.We used the National Cancer Institute(NCI)method to estimate the usual intake of foods.Multivariable logistic regressions were performed to evaluate the association between red meat usual intake and the risk of Met S.Quantile regression analysis was used to study the relationship between red meat consumption and serum ferritin levels.Results After adjusting for potential confounders,red meat,and fresh red meat were positively associated with the risk of Met S(RR=1.41,95%CI:1.05–1.90 and RR=1.37,95%CI:1.02–1.85,respectively).These relationships showed increasing trend(P<0.05).The level of serum ferritin increased significantly with the number of Met S components(P<0.05).The quantile regression analysis showed that red meat and fresh red meat usual intake had a significant positive association with serum ferritin levels across the entire conditional serum ferritin distribution(P<0.05).Processed red meat did not exhibit a similar association.Conclusion Higher red meat usual intake was associated with an increased risk of Met S and elevated serum ferritin levels.
基金This work was supported by a Grant from the State Key Basic Research Program (G1998051203).
文摘Background： In Padova and Vienna International Classification, the usual intestinal metaplasia （UIM） of the stomach, including complete and incomplete type, is defined as negative for dysplasia, and hyperproliferative intestinal metaplasia （HIM） as indefinite for dysplasia, but the biological characteristics of these two types of intestinal metaplasia （IM）remain to be studied. Objective： To investigate the biological differences between UIM, HIM and intestinal type gastric cancer （IGC）, a panel of biomarkers were detected. Methods： A total of 38 cases of IGC, 41 HIM and 56 UIM adjacent to gastric cancer were studied. Immunohistochemistry was used to detect the expressions of pS2, MUC2, MUC5AC, MUC6, Ki-67, EGFR, p53 and sulfo-Lewisa in UIM, HIM and IGC. Microsatellite instability （MSI） in UIM, HIM and IGC was detected by using Denaturing High Performance Liquid Chromatography （DHPLC）. Results： The pS2 antigen expression in UIM （78.6%） was significantly higher than in HIM and IGC （9.8%, 10.5%）, p〈0.01. The MUC6, sulfo-Lewisa and EGFR protein expressions were significant increased in HIM （24.4%, 82.9%, 48.7%） and IGC （34.2%, 75.0%, 42.1%） than in UIM （3.6%, 25.5%, 17.9%）, p〈0.01. A reversed pattern of expressions of MUC2 and MUC5AC was observed in UIM （96.4%, 50.0%） and HIM （82.9%, 36.6%） compared with IGC （52.6%, 13.2%）, p〈0.05; and the p53 gene expression was increased from UIM （1.8%） to HIM （19.5%） to IGC （57.9%）, p〈0.01. The Ki-67 labeling index was significantiy different among three lesions （UIM： 16%±6%, HIM： 45%±9%, IGC： 63%±10%, p〈0.01）. Conclusion： These findings suggest that there are different bio-characteristics among UIM, HIM and IGC, and HIM may have higher potential to progress to more advanced lesions in comparison with UIM.
基金Supported by the National Natural Science Foundation of China under Grant No.19773005.
文摘It is shown that evolution characteristics of black hole(BH)parameters in the pure disk-accretion are determined uniquely by BH spin parameter aa_(*).Some unusual evolution characteristics of the parameters of BH accretion disks,such as angular velocity,temperature and event horizon radius,are investigated in both thin and thick disk-accretion.And the corresponding turning points,a_(*)^(c),are derived.In addition,two characteristic functions describing the evolution of BH parameters are derived for thin and thick disks,respectively.
基金Supported by the National Natural Science Foundation of China.
文摘The usual fermion realizations of quantum algebra S1_(q)(2) defining higher-dimensional representations are built in this letter.Using them,we construct a usual fermion system with quantum group symmetry of S1_(q)(2) as a q-deformation of the pairing correlation model in many-body problems.Its energy spectra are exactly solved out from the representation theory of S1_(q)(2).
基金National Natural Science Foundation of China(Grant Nos.11774309 and 11674283)Natural Science Foundation of Zhejiang Province of China(Grant No.LZ13A040001)。
文摘We study the superfluid behavior of a population imbalanced ultracold atomic Fermi gases with a short range attractive interaction in a one-dimensional(1D)optical lattice,using a pairing fluctuation theory.We show that,besides widespread pseudogap phenomena and intermediate temperature superfluidity,the superfluid phase is readily destroyed except in a limited region of the parameter space.We find a new mechanism for pair hopping,assisted by the excessive majority fermions,in the presence of continuum-lattice mixing,which leads to an unusual constant Bose-Einstein condensate(BEC)asymptote for Tc that is independent of pairing strength.In result,on the BEC side of unitarity,superfluidity,when it exists,may be strongly enhanced by population imbalance.
基金Supported by the National Program on Key Basic Research Project under Grant No.2018YFB0407601the Strategic Priority Research Program of the Chinese Academy of Sciences under Grant Nos.XDB44000000 and QYZDY-SSW-JSC015the National Natural Science Foundation of China under Grant Nos.11874349 and 11774339。
文摘An ultra-thin Co2MnSi(0.5 nm)/Mn Ga(1.5 nm) bilayer capped with Pt(5 nm) has been successfully grown by molecular-beam epitaxy.It is a potential candidate of synthetic antiferromagnets due to antiferromagnetic coupling between Co2MnSi and MnGa,which is a promising skyrmion-racetrack-memory medium without skyrmion Hall effect after capping with a Pt layer.Unusual humps in transverse Hall resistance loops are clearly observed in the temperature range from 260 to 400 K.This anomaly is generally attributed to topological Hall effect,but other than that,we prove that non-uniform rotation of magnetic moments in the bilayer with magnetic field sweeping is also a possible mechanism contributed to the unusual hump.
基金supported by Natural Science Foundation(No.71173131)National Program on Key BasicResearch Projects(No.2010CB95500)of China
文摘Business as Usual （BaU） scenario in developing countries has been a debated issue in climate change negotiations. This paper analyzes different definitions of BaU and points out that the major difference among these definitions is how to set the starting point of BaU projections, that is the so called base year. Some international institutions use current policy scenarios to project a BaU trajectory of developing countries. Such definition will lead to an underestimation of BaU emissions of developing countries and thus an underestimation of mitigation efforts. This paper concludes with a suggestion to use a without policy scenario with a clear base year as definition of BaU. Such a definition will set an objective benchmark to assess mitigation efforts of develonin countries.
文摘When assessing food intake patterns in groups of individuals, a major problem is finding usual intake distribution. This study aimed at searching for a probability distribution to estimate the usual intake of nutrients using data from a cross-sectional investigation on nutrition students from a public university in Sao Paulo state, Brazil. Data on 119 women aged 19 to 30 years old were used. All women answered a questionnaire about their lifestyle, diet and demographics. Food intake was evaluated from a non-consecutive three-day 24-hour food record. Different probability distributions were tested for vitamins C and E, panthotenic acid, folate, zinc, copper and calcium where data normalization was not possible. Empirical comparisons were performed, and inadequacy prevalence was calculated by comparing with the NRC method. It was concluded that if a more realistic distribution for usual intake is found, results can be more accurate as compared to those achieved by other methods.
文摘Objective： To assess whether adherence to amiodarone monitoring differed pre- and post-amiodarone restriction template and implementation of the pharmacist-managed clinic. Design： This was a retrospective chart review study. Setting： A large, academically-affiliated Veteran Affairs Healthcare System providing primary and tertiary care. Patients： 580 patients were identified as having an active prescription for amiodarone for at least 60 days from January l, 2009 to August 31, 2013 and receiving primary care at the VAAHS （Veterans Affairs Ann Arbor Healthcare System）. Results： Nearly all patients had TSH and LFTs at baseline regardless of study group. Significant associations between baseline rates for CXR, ECG, PFT, and opbthalmologic exams were found, with higher rates in the clinic and template arms compared to usual care. Similar patterns for all monitoring outcome rates were also found for both the 6- and 12-month measures. Conclusions： Patients on amiodarone who are followed by a pharmacist-managed clinic or where a restricted ordering template was used had increased compliance with amiodarone monitoring guidelines compared to usual care. Use of a restricted template may be a reasonable option in place of a pharmacist-managed service.
基金supported by the research project of Russian Science Foundation N 22-14-00227.
文摘Dear Editor,The problem of age estimation in amphibians and reptiles with annual fluctuations of growth pattern has been considered to be mostly solved since the skeletochronological method was introduced(Kleinenberg and Smirina,1969).This method is based on counting the number of lines of arrested growth(LAGs)—cyclical growth marks that are usually formed annually and characterized by different optical aspects within the tubular bones.
文摘One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan,reaching zero production in 2015.In response,the country started importing more fossil energy including coal,oil,and natural gas to fill the energy gap.However,this led to a significant increase in carbon emissions,hindering the efforts to reduce its carbon footprint.In the current situation,Japan is actively working to balance its energy requirements with environmental considerations,including the utilization of hydrogen fuel.Therefore,this paper aims to explore the feasibility and implications of using hydrogen power plants as a means to reduce emissions,and this analysis will be conducted using the energy modeling of the MARKAL-TIMES Japan framework.The hydrogen scenario(HS)is assumed with the extensive integration of hydrogen into the power generation sector,supported by a hydrogen import scheme.Additionally,this scenario will be compared with the Business as Usual(BAU)scenario.The results showed that the generation capacities of the BAU and HS scenarios have significantly different primary energy supplies.The BAU scenario is highly dependent on fossil fuels,while the HS scenario integrates hydrogen contribution along with an increase in renewable energy,reaching a peak contribution of 2,160 PJ in 2050.In the HS scenario,the target of reducing CO_(2) emissions by 80%is achieved through significant hydrogen penetration.By 2050,the total CO_(2) emissions are estimated to be 939 million tons for the BAU scenario and 261 million tons for the Hydrogen scenario.In addition,the contribution of hydrogen to electricity generation is expected to be 153 TWh,smaller than PV and wind power.
